Yijun Zhang
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View article: Vertebral artery occlusion mediated cerebellar and spinal cord infarction: A case report
Vertebral artery occlusion mediated cerebellar and spinal cord infarction: A case report Open
Rationale: This case report describes a rare instance of concurrent acute cerebellar and spinal cord infarction caused by right vertebral artery occlusion, providing dynamic angiographic visualization of the collateral circulation. Patient…
View article: Previous Antiplatelet Therapy on Ticagrelor-Aspirin and Clopidogrel-Aspirin Efficacy in Intracranial Artery Stenosis
Previous Antiplatelet Therapy on Ticagrelor-Aspirin and Clopidogrel-Aspirin Efficacy in Intracranial Artery Stenosis Open
Background and Purpose This study aims to investigate the effects of previous antiplatelet therapy on the efficacy and safety of ticagrelor-aspirin versus clopidogrel-aspirin among patients with and without intracranial artery stenosis (IC…
View article: RIMA-SVG versus Ao-SVG in coronary artery bypass grafting: protocol for a prospective, randomised, double-blind, non-inferiority and single-centre trial
RIMA-SVG versus Ao-SVG in coronary artery bypass grafting: protocol for a prospective, randomised, double-blind, non-inferiority and single-centre trial Open
Introduction Coronary artery bypass grafting (CABG) is a standard treatment for coronary artery disease, particularly in patients with multivessel disease. Connecting the saphenous vein graft (SVG) to the right internal mammary artery (RIM…
View article: The Impact of Riblet Walls on the Structure of Liquid–Solid Two-Phase Turbulent Flow: Streak Structures and Burst Events
The Impact of Riblet Walls on the Structure of Liquid–Solid Two-Phase Turbulent Flow: Streak Structures and Burst Events Open
This study employs Particle Image Velocimetry (PIV) technology to investigate the statistical properties and flow structures of the turbulent boundary layer over smooth walls and riblet walls with yaw angles of 0, ±30° in both clear water …
View article: Sex-specific association between body roundness index and cognitive impairment among hospitalized middle-aged and elderly patients with type 2 diabetes in China: a cross-sectional analysis
Sex-specific association between body roundness index and cognitive impairment among hospitalized middle-aged and elderly patients with type 2 diabetes in China: a cross-sectional analysis Open
Our findings suggest that BRI was as effective predictor of CI and showed superior predictive accuracy in women than men. In clinical practice, BRI could be used to assess CI among middle-aged and elderly individuals with T2D.
View article: Visualization of research trend of neoadjuvant chemotherapy for breast cancer treatment: a bibliometric analysis
Visualization of research trend of neoadjuvant chemotherapy for breast cancer treatment: a bibliometric analysis Open
This study presents a bibliometric analysis on NAC for breast cancer, highlighting research trends, influential studies, and collaborative networks. This data analysis highlights key research gaps in NAC for breast cancer, including limite…
View article: Influencing factors of chemotherapy-related cognitive impairment in patients with breast cancer
Influencing factors of chemotherapy-related cognitive impairment in patients with breast cancer Open
Introduction: The chemotherapy-related cognitive impairment is common, but the influencing factors and effective intervention measures are not well known. Objective: To investigate the changes of cognitive function in breast cancer patient…
View article: RC48-ADC monotherapy or in combination with immunotherapy for locally advanced or metastatic urothelial carcinoma with HER2 low and null expression: a multicenter, real-world, retrospective study
RC48-ADC monotherapy or in combination with immunotherapy for locally advanced or metastatic urothelial carcinoma with HER2 low and null expression: a multicenter, real-world, retrospective study Open
RC48-ADC demonstrated favorable efficacy and manageable safety in la/mUC patients with HER2 low and null expression in real-world settings. Prospective studies with large sample size are warranted to validate this finding.
View article: Structural characteristics of uniform momentum zones in turbulent boundary layers for Reynolds number below 1000
Structural characteristics of uniform momentum zones in turbulent boundary layers for Reynolds number below 1000 Open
This study experimentally investigates the structural evolution of uniform momentum zones (UMZs) in a fully developed planar turbulent boundary layer. The friction Reynolds number (Reτ) in the detection region ranges up to 1000. Instantane…
View article: Association between HALP (hemoglobin, albumin, lymphocyte, and platelet) score and poor outcomes in acute ischemic stroke patients with type 2 diabetes mellitus: a study from the Third China National Stroke Registry
Association between HALP (hemoglobin, albumin, lymphocyte, and platelet) score and poor outcomes in acute ischemic stroke patients with type 2 diabetes mellitus: a study from the Third China National Stroke Registry Open
Background The combined index (HALP) of hemoglobin, albumin, lymphocytes, and platelets is considered a novel scoring system that reflects systemic inflammation and nutritional status. This study aimed to investigate the relationship betwe…
View article: Resilience Development Among Adult Patients With De Novo Acute Leukemia: A Qualitative Study
Resilience Development Among Adult Patients With De Novo Acute Leukemia: A Qualitative Study Open
Objective This study aimed to explore the development process of psychological resilience among adult patients with de novo acute leukemia. Methods This study utilized a descriptive qualitative approach, employing a purposeful sampling met…
View article: J-shaped relationship of serum neurofilament light chain with urinary albumin excretion in US adults: NHANES 2013–2014
J-shaped relationship of serum neurofilament light chain with urinary albumin excretion in US adults: NHANES 2013–2014 Open
The study found a J-shaped curve linking sNfL and uACR in American adults, with a turning point around log(sNfL) 2.928 pg/mL.
View article: Monocyte Chemoattractant Protein‐1, Inflammatory Biomarkers, and Prognosis of Patients With Ischemic Stroke or Transient Ischemic Attack: Fndings From a Nationwide Registry Study
Monocyte Chemoattractant Protein‐1, Inflammatory Biomarkers, and Prognosis of Patients With Ischemic Stroke or Transient Ischemic Attack: Fndings From a Nationwide Registry Study Open
Background Recent Mendelian randomization and meta‐analysis highlight the relevance of MCP‐1 (monocyte chemoattractant protein‐1) in stroke. We aimed to investigate the associations between MCP‐1 and clinical outcomes in patients with isch…
View article: Correlation Analysis of Multi-Scale Ictal EEG Signals in Juvenile Myoclonic Epilepsy
Correlation Analysis of Multi-Scale Ictal EEG Signals in Juvenile Myoclonic Epilepsy Open
Background: To explore the time-frequency structure and cross-scale coupling of electroencephalography (EEG) signals during seizure in juvenile myoclonic epilepsy (JME), correlations between different leads, as well as dynamic evolution in…
View article: Wavelet Entropy Analysis of Electroencephalogram Signals During Wake and Different Sleep Stages in Patients with Insomnia Disorder
Wavelet Entropy Analysis of Electroencephalogram Signals During Wake and Different Sleep Stages in Patients with Insomnia Disorder Open
Wavelet entropy can reflect the changes in the complexity of EEG signals during wake and different sleep stages in patients with insomnia disorder, which provides a new method and insights about understanding of pathophysiological mechanis…
View article: Low-Density Lipoprotein Cholesterol to Triglyceride Ratio and Clinical Outcomes after Acute Ischaemic Stroke or Transient Ischaemic Attack
Low-Density Lipoprotein Cholesterol to Triglyceride Ratio and Clinical Outcomes after Acute Ischaemic Stroke or Transient Ischaemic Attack Open
LDL-C/TG ratio was associated with the risk of stroke recurrence, composite vascular events, death and poor functional outcome in patients with AIS or TIA.
View article: Quantification of eosinophilic area and its potential molecular feature in clear cell renal cell carcinoma
Quantification of eosinophilic area and its potential molecular feature in clear cell renal cell carcinoma Open
Objective Previous studies have acknowledged the presence of eosinophilic cytoplasm in clear cell renal cell carcinoma, yet the precise quantification method and potential molecular attributes in clear cell renal cell carcinoma remain elus…
View article: Roles of general and central adiposity in cardiometabolic multimorbidity: revisiting the obesity paradox using a multistate model
Roles of general and central adiposity in cardiometabolic multimorbidity: revisiting the obesity paradox using a multistate model Open
Objective The objective of this study was to evaluate the associations of general and central obesity with risk of first cardiometabolic disease (FCMD), cardiometabolic multimorbidity (CMM), and death. Methods A total of 86,169 participant…
View article: Cardiovascular health and life expectancy with and without cardiovascular disease in the middle-aged and elderly Chinese population
Cardiovascular health and life expectancy with and without cardiovascular disease in the middle-aged and elderly Chinese population Open
Background High cardiovascular health (CVH) was associated with lower risk of cardiovascular disease (CVD) and longer life expectancy. However, whether life years lived without CVD could increase faster than or at least at the same pace as…
View article: Magnitude and time course of insulin resistance accumulation with the risk of cardiovascular disease: an 11-years cohort study
Magnitude and time course of insulin resistance accumulation with the risk of cardiovascular disease: an 11-years cohort study Open
Background The risk of cardiovascular disease (CVD) depended on the magnitude and exposure duration of insulin resistance (IR). This study aimed to investigate the associations of cumulative metabolic score for IR (cumMETS-IR) with inciden…
View article: Baseline and longitudinal cardiovascular health using Life’s Essential 8 metrics with the risk of incident hypertension
Baseline and longitudinal cardiovascular health using Life’s Essential 8 metrics with the risk of incident hypertension Open
A higher CVH score assessed by new LE8 is associated with a lower risk of subsequent hypertension, especially young adults and women.
View article: Efficacy and safety of perampanel as early add-on therapy in Chinese patients with focal-onset seizures: a multicenter, open-label, single-arm study
Efficacy and safety of perampanel as early add-on therapy in Chinese patients with focal-onset seizures: a multicenter, open-label, single-arm study Open
Background No interventional study has been conducted in China to assess efficacy and safety of perampanel in treating Chinese patients with epilepsy, nor has there been any study on perampanel early add-on therapy in China. This intervent…
View article: The impact of serum acid, arterial stiffness, and hypertension as a mediating factor: A cohort study
The impact of serum acid, arterial stiffness, and hypertension as a mediating factor: A cohort study Open
Our study indicates that SUA was positively associated with the risk of arterial stiffness and its progression, especially in women. The association was mainly mediated through hypertension.
View article: Association between cumulative atherogenic index of plasma exposure and risk of myocardial infarction in the general population
Association between cumulative atherogenic index of plasma exposure and risk of myocardial infarction in the general population Open
Background Atherogenic index of plasma (AIP) has been confirmed as a novel marker for myocardial infarction (MI), but few evidence on the long-term AIP and MI risk in general populations. We thus aimed to evaluate the relationships of cumu…