Yi‐Ting Shen
YOU?
Author Swipe
View article: Lineage Tracing Reveals a Shared Cellular Origin for Supraclavicular Brown and Inguinal Beige Adipocytes
Lineage Tracing Reveals a Shared Cellular Origin for Supraclavicular Brown and Inguinal Beige Adipocytes Open
Summary The metabolic importance of brown adipose tissue (BAT) has been recognized, but the origins of BAT, particularly supraclavicular BAT (scBAT), are less clear. Here, we traced the origin of scBAT to Mef2c-anterior heart field (AHF)-m…
View article: Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway
Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway Open
Background The clinical application of recombinant tissue plasminogen activator (rt-PA) is significantly constrained by hemorrhagic transformation (HT), a common and severe complication following thrombolysis for ischemic stroke. Notably, …
View article: AutoComPose: Automatic Generation of Pose Transition Descriptions for Composed Pose Retrieval Using Multimodal LLMs
AutoComPose: Automatic Generation of Pose Transition Descriptions for Composed Pose Retrieval Using Multimodal LLMs Open
Composed pose retrieval (CPR) enables users to search for human poses by specifying a reference pose and a transition description, but progress in this field is hindered by the scarcity and inconsistency of annotated pose transitions. Exis…
View article: A conditional denoising VAE-based framework for antimicrobial peptides generation with preserving desirable properties
A conditional denoising VAE-based framework for antimicrobial peptides generation with preserving desirable properties Open
Motivation The widespread use of antibiotics has led to the emergence of resistant pathogens. Antimicrobial peptides (AMPs) combat bacterial infections by disrupting the integrity of cell membranes, making it challenging for bacteria to de…
View article: EgoFall: Real-time Privacy-Preserving Fall Risk Assessment with a Single On-Body Tracking Camera
EgoFall: Real-time Privacy-Preserving Fall Risk Assessment with a Single On-Body Tracking Camera Open
Falls are a leading cause of injury among older adults, with research indicating that they often fall due to certain individual biomechanical factors. Therefore, real-time individual fall risk assessment is essential for designing more eff…
View article: Approaches to Monkeypox Outbreak Control：A Focus on Technology and Innovation
Approaches to Monkeypox Outbreak Control：A Focus on Technology and Innovation Open
The global outbreak of the monkeypox virus (MPXV) has necessitated the urgent identification of effective strategies for outbreak control. This essay focuses on the role of technology and innovation in addressing monkeypox outbreaks, aimin…
View article: Electroacupuncture extends the time window of thrombolytic therapy in rats by reducing disruptions of blood–brain barrier and inhibiting GSDMD-mediated pyroptosis
Electroacupuncture extends the time window of thrombolytic therapy in rats by reducing disruptions of blood–brain barrier and inhibiting GSDMD-mediated pyroptosis Open
EA may be a promising therapeutic approach for extending the thrombolytic therapy window by protecting the BBB and inhibiting GSDMD-mediated pyroptosis.
View article: SynPlay: Large-Scale Synthetic Human Data with Real-World Diversity for Aerial-View Perception
SynPlay: Large-Scale Synthetic Human Data with Real-World Diversity for Aerial-View Perception Open
We introduce SynPlay, a large-scale synthetic human dataset purpose-built for advancing multi-perspective human localization, with a predominant focus on aerial-view perception. SynPlay departs from traditional synthetic datasets by addres…
View article: Tissue Culture Response and In Vitro Plant Regeneration of Malus ‘Baiyun’ (a New Cultivar of Ornamental Crabapple)
Tissue Culture Response and In Vitro Plant Regeneration of Malus ‘Baiyun’ (a New Cultivar of Ornamental Crabapple) Open
Malus ‘Baiyun’ (registration no. 20210210), a new crabapple cultivar, was registered in 2021 by the Nanjing Forestry Unversity. However, the difficult rooting has greatly limited the production of high-quality M. ‘Baiyun’ in industrializat…
View article: Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition
Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition Open
Human noroviruses (HuNoVs) are a diverse group of RNA viruses that cause endemic and pandemic acute viral gastroenteritis. Previously, we reported that many HuNoV strains require bile or bile acid (BA) to infect human jejunal intestinal en…
View article: Diversifying Human Pose in Synthetic Data for Aerial-view Human Detection
Diversifying Human Pose in Synthetic Data for Aerial-view Human Detection Open
Synthetic data generation has emerged as a promising solution to the data scarcity issue in aerial-view human detection. However, creating datasets that accurately reflect varying real-world human appearances, particularly diverse poses, r…
View article: Exploring the Impact of Synthetic Data for Aerial-view Human Detection
Exploring the Impact of Synthetic Data for Aerial-view Human Detection Open
Aerial-view human detection has a large demand for large-scale data to capture more diverse human appearances compared to ground-view human detection. Therefore, synthetic data can be a good resource to expand data, but the domain gap with…
View article: Efficacy and safety of ultrasound-assisted wound debridement in the treatment of diabetic foot ulcers: a systematic review and meta-analysis of 11 randomized controlled trials
Efficacy and safety of ultrasound-assisted wound debridement in the treatment of diabetic foot ulcers: a systematic review and meta-analysis of 11 randomized controlled trials Open
Objective Research data suggests that ultrasound-assisted wound debridement (UAWD) can effectively promote the healing of diabetic foot ulcers (DFU). However, existing research is not consistent with this viewpoint. Therefore, we conducted…
View article: MEMO: dataset and methods for robust multimodal retinal image registration with large or small vessel density differences
MEMO: dataset and methods for robust multimodal retinal image registration with large or small vessel density differences Open
The measurement of retinal blood flow (RBF) in capillaries can provide a powerful biomarker for the early diagnosis and treatment of ocular diseases. However, no single modality can determine capillary flowrates with high precision. Combin…
View article: Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition
Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition Open
Human noroviruses (HuNoVs) are a diverse group of RNA viruses that cause both endemic and pandemic acute viral gastroenteritis. Previously we reported that many strains of HuNoV require bile or bile acid (BA) to infect human jejunal intest…
View article: ShellCollect: A Framework for Smart Precision Shellfish Harvesting Using Data Collection Path Planning
ShellCollect: A Framework for Smart Precision Shellfish Harvesting Using Data Collection Path Planning Open
Shellfish aquaculture significantly contributes to the coastal economy of the United States. However, the current primary and most productive harvesting method for on-bottom shellfish farming—dredging with tow dredges —is highly inefficien…
View article: MEMO: Dataset and Methods for Robust Multimodal Retinal Image Registration with Large or Small Vessel Density Differences
MEMO: Dataset and Methods for Robust Multimodal Retinal Image Registration with Large or Small Vessel Density Differences Open
The measurement of retinal blood flow (RBF) in capillaries can provide a powerful biomarker for the early diagnosis and treatment of ocular diseases. However, no single modality can determine capillary flowrates with high precision. Combin…
View article: Transcriptome Dynamics during Spike Differentiation of Wheat Reveal Amazing Changes in Cell Wall Metabolic Regulators
Transcriptome Dynamics during Spike Differentiation of Wheat Reveal Amazing Changes in Cell Wall Metabolic Regulators Open
Coordinated cell proliferation and differentiation result in the complex structure of the inflorescence in wheat. It exhibits unique differentiation patterns and structural changes at different stages, which have attracted the attention of…
View article: A Surprising Diversity of Xyloglucan Endotransglucosylase/Hydrolase in Wheat: New in Sight to the Roles in Drought Tolerance
A Surprising Diversity of Xyloglucan Endotransglucosylase/Hydrolase in Wheat: New in Sight to the Roles in Drought Tolerance Open
Drought has become a major limiting factor for wheat productivity, and its negative impact on crop growth is anticipated to increase with climate deterioration in arid areas. Xyloglucan endoglycosylases/hydrolases (XTHs) are involved in co…
View article: Archangel: A Hybrid UAV-Based Human Detection Benchmark With Position and Pose Metadata
Archangel: A Hybrid UAV-Based Human Detection Benchmark With Position and Pose Metadata Open
Learning to detect objects, such as humans, in imagery captured by an unmanned aerial vehicle (UAV) usually suffers from tremendous variations caused by the UAV’s position towards the objects. In addition, existing UAV-based benchmark data…
View article: Controllable mitochondrial aggregation and fusion by a programmable DNA binder
Controllable mitochondrial aggregation and fusion by a programmable DNA binder Open
DNA nano-binder has been designed as the artificial controller for the aggregation and fusion of mitochondria in living cells.
View article: Progressive Transformation Learning for Leveraging Virtual Images in Training
Progressive Transformation Learning for Leveraging Virtual Images in Training Open
To effectively interrogate UAV-based images for detecting objects of interest, such as humans, it is essential to acquire large-scale UAV-based datasets that include human instances with various poses captured from widely varying viewing a…
View article: Controllable mitochondrial aggregation and fusion by a programmable DNA binder
Controllable mitochondrial aggregation and fusion by a programmable DNA binder Open
DNA nanodevices have been feasibly applied for various chemo-biological applications, but their functions as precise regulators of intracellular organelles are still limited. Here, we report a synthetic DNA binder that can artificially ind…
View article: Archangel: A Hybrid UAV-based Human Detection Benchmark with Position and Pose Metadata
Archangel: A Hybrid UAV-based Human Detection Benchmark with Position and Pose Metadata Open
Learning to detect objects, such as humans, in imagery captured by an unmanned aerial vehicle (UAV) usually suffers from tremendous variations caused by the UAV's position towards the objects. In addition, existing UAV-based benchmark data…
View article: Decreased accuracy of erythrocyte sedimentation rate in diagnosing osteomyelitis in diabetic foot infection patients with severe renal impairment: A retrospective cross-sectional study
Decreased accuracy of erythrocyte sedimentation rate in diagnosing osteomyelitis in diabetic foot infection patients with severe renal impairment: A retrospective cross-sectional study Open
Background Rapid diagnosis and treatment of diabetic foot osteomyelitis (DFO) could reduce the risk of amputation and death in patients with diabetic foot infection (DFI). Erythrocyte sedimentation rate (ESR) is considered the most useful …
View article: Comparative Characterization of CpCDPK1 and CpCDPK9, Two Potential Drug Targets Against Cryptosporidiosis
Comparative Characterization of CpCDPK1 and CpCDPK9, Two Potential Drug Targets Against Cryptosporidiosis Open
As the invasion, egress, and growth of Cryptosporidium spp. are regulated by the calcium ion, calcium-dependent protein kinases (CDPKs) are considered potential drug targets against these pathogens. In this study, we expressed CpCDPK1 of C…
View article: Hsa_circ_0024093 accelerates VSMC proliferation via miR-4677-3p/miR-889-3p/USP9X/YAP1 axis in in vitro model of lower extremity ASO
Hsa_circ_0024093 accelerates VSMC proliferation via miR-4677-3p/miR-889-3p/USP9X/YAP1 axis in in vitro model of lower extremity ASO Open
View article: What Synthesis is Missing: Depth Adaptation Integrated with Weak Supervision for Indoor Scene Parsing
What Synthesis is Missing: Depth Adaptation Integrated with Weak Supervision for Indoor Scene Parsing Open
Scene Parsing is a crucial step to enable autonomous systems to understand and interact with their surroundings. Supervised deep learning methods have made great progress in solving scene parsing problems, however, come at the cost of labo…
View article: Qingre Baidu mixture‑induced effect of AI‑2 on Staphylococcus�aureus and Pseudomonas�aeruginosa biofilms in chronic and refractory wounds
Qingre Baidu mixture‑induced effect of AI‑2 on Staphylococcus�aureus and Pseudomonas�aeruginosa biofilms in chronic and refractory wounds Open
The present study aimed to investigate the effect of the traditional Chinese medicine Qingre Baidu mixture (QBM) on the regulation of various parameters, including the morphology of bacterial biofilms, the bacterial density sensing system,…
View article: An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example
An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example Open
This study provided a new integrated strategy to identify new targets of bioactive compounds and reveal their molecular mechanisms of action.