Isabel Elaine Allen
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View article: General Health and Mental Health Locus of Control in a Diverse Sample of Latino San Franciscans Attending a Community‐Based Primary Care Clinic
General Health and Mental Health Locus of Control in a Diverse Sample of Latino San Franciscans Attending a Community‐Based Primary Care Clinic Open
Background A more integrated approach to mental and brain health across the lifespan is needed. Understanding how individuals in a specific community perceive control over their health outcomes may provide insights for multidimensional and…
View article: Tablet‐based cognitive assessment in a multisite study of early‐onset AD: association with pen‐and‐paper tests and PET measures of amyloid and tau
Tablet‐based cognitive assessment in a multisite study of early‐onset AD: association with pen‐and‐paper tests and PET measures of amyloid and tau Open
Background People living with early‐onset Alzheimer's disease (EOAD) are often misdiagnosed or experience delays in diagnoses due to their young age of onset, non‐amnestic presentation, and rapid clinical progression. Brief digital cogniti…
View article: Musical rhythm production associates with cognitive functioning in healthy older adults
Musical rhythm production associates with cognitive functioning in healthy older adults Open
Background Music‐based interventions associate with improvements in cognitive and social outcomes in older adults living with and without dementia. Understanding age‐related alterations of rhythm performance in older adults is necessary to…
View article: Cross‐linguistic characterization of speech and language profiles of English, Chinese, and Italian Primary Progressive Aphasia patients: a data‐driven approach
Cross‐linguistic characterization of speech and language profiles of English, Chinese, and Italian Primary Progressive Aphasia patients: a data‐driven approach Open
Background Speech and language profile of Primary Progressive Aphasia (PPA) has primarily been described based on English‐speaking cohorts. However, the potential influence of language typology in the clinical manifestation of PPA remains …
View article: Digits Across Languages: The Role of Lexical and Numerical Characteristics in Digit Span Performance Across Fourteen Languages
Digits Across Languages: The Role of Lexical and Numerical Characteristics in Digit Span Performance Across Fourteen Languages Open
Background The digit span task, a measure of auditory verbal short‐term and working memory, is widely used globally. Emerging research has revealed variations in digit span performance across languages among young adults; however, studies …
View article: Neuropathological comorbidities in Frontotemporal Lobar Degeneration: Implications for Diagnosis
Neuropathological comorbidities in Frontotemporal Lobar Degeneration: Implications for Diagnosis Open
Background Frontotemporal lobar degeneration (FTLD) is an umbrella term encompassing neurodegenerative diseases that either feature tau, TDP‐43, or FET inclusions. As FTLD is associated with a younger age of onset, there has been less focu…
View article: Does Bilingualism Have a Protective Effect on Cognitive Reserve Amongst FTD Variants?
Does Bilingualism Have a Protective Effect on Cognitive Reserve Amongst FTD Variants? Open
Background Prior research studies report conflicting evidence regarding the role of bilingualism as a protective factor in cognitive reserve. While it is known that Behavioral Variant Frontotemporal Dementia (bvFTD) and Primary Progressive…
View article: Deciphering Dyslexia Phenotypes in Chinese Language Users with Primary Progressive Aphasia
Deciphering Dyslexia Phenotypes in Chinese Language Users with Primary Progressive Aphasia Open
Background The diverse typology of languages often precipitates distinct language‐specific symptomatologies. While dyslexia and dysgrahia are included in the diagnostic criteria of Primary Progressive Aphasia (PPA), the descriptions predom…
View article: Feasibility and Determinants of Performance for a Tablet‐based Cognitive Assessment Tool in Rural and Urban Southeast Nigeria
Feasibility and Determinants of Performance for a Tablet‐based Cognitive Assessment Tool in Rural and Urban Southeast Nigeria Open
Background Cognitive assessment ideally is a critical element of clinical evaluations for individuals with dementia and Alzheimer's disease in Primary Health Care (PHC) settings. To examine the feasibility and demographic determinants of p…
View article: Development and suitability of neuropsychological assessment batteries among seniors in Tanzania: Clinical and research implications of the Tanzania 2022 Population and Housing Census
Development and suitability of neuropsychological assessment batteries among seniors in Tanzania: Clinical and research implications of the Tanzania 2022 Population and Housing Census Open
Background Currently, dementia affects over 57 million people across the world and over two‐thirds live in low‐and‐middle‐income countries (LMICs) where over 75% (28.5million) remains undiagnosed. The identification of dementia using valid…
View article: Tablet‐based Cognitive Assessment Tool (TabCAT) in a multisite study of early‐onset Alzheimer's disease
Tablet‐based Cognitive Assessment Tool (TabCAT) in a multisite study of early‐onset Alzheimer's disease Open
INTRODUCTION Brief digital cognitive measures may be a valuable and scalable alternative to traditional tests for improving early detection and disease monitoring in patients with early‐onset Alzheimer's disease (EOAD). METHODS We examined…
View article: Corrigendum to ‘Volatile pyrethroid spatial repellents for preventing mosquito bites: a systematic review and meta-analysis’ EBioMedicine Volatile pyrethroid spatial repellents for preventing mosquito bites: a systematic review and meta-analysis 119 (2025) 105891/10.1016/j.ebiom.2025.105891 Sep: 119: 105891
Corrigendum to ‘Volatile pyrethroid spatial repellents for preventing mosquito bites: a systematic review and meta-analysis’ EBioMedicine Volatile pyrethroid spatial repellents for preventing mosquito bites: a systematic review and meta-analysis 119 (2025) 105891/10.1016/j.ebiom.2025.105891 Sep: 119: 105891 Open
The authors regret that there was an error for the affiliation of Arissara Pongsiri and Alongkot Ponlawat. This has been corrected to their affiliation at the Department of Entomology, Armed Forces Research Institute of Medical Sciences (A…
View article: Lab tests can be used to predict phosphatidylethanol-measured high-risk alcohol use among people with HIV: a proof-of-concept using machine learning
Lab tests can be used to predict phosphatidylethanol-measured high-risk alcohol use among people with HIV: a proof-of-concept using machine learning Open
Background Unhealthy alcohol use is prevalent among persons with HIV (PWH) and is associated with adverse outcomes, but is underestimated partly due to use of self-reported measures prone to underreporting. Phosphatidylethanol (PEth) is a …
View article: Effects of dance interventions on brain health for older adults with cognitive impairment: an umbrella review
Effects of dance interventions on brain health for older adults with cognitive impairment: an umbrella review Open
Dementia is increasing globally, expected to affect 153 million people by 2050. Dance is an emerging non-pharmacological evidence-based intervention, that integrates artistic, aesthetic, and physical exercise domains. This umbrella review …
View article: Speaking in Tones: The role of lexical tones in Chinese-speaking Primary Progressive Aphasia
Speaking in Tones: The role of lexical tones in Chinese-speaking Primary Progressive Aphasia Open
Two-thirds of the world’s languages, including Mandarin and Cantonese, employ pitch variation to convey meaning (lexical tone). Existing diagnostic frameworks for primary progressive aphasia (PPA) have been developed for English speakers, …
View article: Burden of psychiatric disease inversely correlates with Alzheimer's age at onset
Burden of psychiatric disease inversely correlates with Alzheimer's age at onset Open
INTRODUCTION Depression is regarded as a risk factor for Alzheimer's disease (AD). Associations between AD and other psychiatric disorders are less clear. METHODS We screened 1,500 AD UCSF Memory and Aging Center patients for prevalence of…
View article: The return home model: design and implementation of a geriatric home-care model for long-term care eligible older adults
The return home model: design and implementation of a geriatric home-care model for long-term care eligible older adults Open
Background Most older adults prefer to “age in place” within their communities. This preference cannot always be honored and dependent older adults may transfer to a long-term care facility. The Return Home is an Israel Ministry of Health …
View article: Alcohol interventions for persons with HIV: Meta-analysis of randomized controlled trials using phosphatidylethanol and self-report
Alcohol interventions for persons with HIV: Meta-analysis of randomized controlled trials using phosphatidylethanol and self-report Open
Results confirm prior findings of significant efficacy of alcohol interventions for PWH. Effect sizes were small across measurements, while heterogeneity was high when using self-report alone. Combined PEth/self-report is a useful primary …
View article: Neurodevelopment and neural environment inform Alzheimer's disease age at onset and phenotype
Neurodevelopment and neural environment inform Alzheimer's disease age at onset and phenotype Open
INTRODUCTION Risk factors associated with sporadic non‐amnestic and early‐onset Alzheimer's disease (AD) remain underexamined. METHODS We investigated a large, clinically heterogeneous, AD cohort for frequencies of established risk factors…
View article: Comorbidities associated with a clinically-recognized delirium diagnosis in the hospital using real world data
Comorbidities associated with a clinically-recognized delirium diagnosis in the hospital using real world data Open
Background Delirium is a mental condition defined as fluctuating disturbances in attention, awareness, and cognition. It is often seen in older, hospitalized patients and is currently hard to predict, with long- and short-term outcomes bei…
View article: Evaluating administrative measures of school quality as mediators of the relationship between attending a segregated school and cognitive function among older Black individuals: the STAR study
Evaluating administrative measures of school quality as mediators of the relationship between attending a segregated school and cognitive function among older Black individuals: the STAR study Open
Research highlights school segregation's impact on cognitive aging for older Black adults, yet the mediating role of school quality—reflecting systemic (dis)investment in segregated schools—remains unexplored. This study included 726 commu…
View article: Parkinson's disease associated with <i>LRRK2</i> -R1441C mutation: Characterization and comparison with other <i>LRRK2</i> mutations
Parkinson's disease associated with <i>LRRK2</i> -R1441C mutation: Characterization and comparison with other <i>LRRK2</i> mutations Open
Mutations in the leucine-rich repeat kinase 2 ( LRRK2 ) gene associate with familial and sporadic Parkinson's disease (PD). While various LRRK2 allelic variants have been studied, characteristics of R1441C carriers remain underexplored. We…
View article: Comorbid Urolithiasis Significantly Increases Utilization Across Healthcare Settings for Individuals With Spina Bifida
Comorbid Urolithiasis Significantly Increases Utilization Across Healthcare Settings for Individuals With Spina Bifida Open
Urolithiasis in individuals with SB disproportionately increases healthcare utilization. Increasing comorbidity is associated with increased risk of encounters for SB-Stone patients, further amplifying the vulnerability of this patient pop…
View article: Figure S5 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018
Figure S5 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018 Open
Findings for racial segregation
View article: Data from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018
Data from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018 Open
Background:Residential segregation limits the access to resources, primarily because of disinvestment. This study evaluated the association between residential segregation and colorectal cancer screening in the United States and whether fi…
View article: Table S1 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018
Table S1 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018 Open
Estimates of main analysis
View article: Figure S1 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018
Figure S1 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018 Open
Maps showing distribution of ICE measures in the US