Explanipedia

Racial disparities in the cause of death among patients with lung cancer in the United States Open

Zhao Yong-sheng, Gu‐Ha Alai, Hang Long, Chuan Zhong, Yi‐Dan Lin · 2025

Our findings reveal persistent racial disparities among lung cancer patients, providing a theoretical basis for interventions to eliminate health disparities.

Machine learning model for predicting tertiary lymphoid structures and treatment response in triple-negative breast cancer Open

Yi‐Dan Lin, Yushuai Yu, Qing Wang, Kaiyan Huang, Shuai Guo , et al. · 2025

The Long Noncoding RNA LINC02820 Promotes Tumor Growth and Metastasis Through Regulating MYH9 Expression in Esophageal Squamous Cell Carcinoma Open

Xiaomin Xu, Xinru Mao, Wenrong Liu, Yue Ming, Tingting Zhang , et al. · 2025

Long noncoding RNAs (lncRNAs) play important roles in tumorigenesis, but their biological functions and mechanisms in esophageal squamous cell carcinoma (ESCC) remain poorly understood. In this study, we employed high‐throughput sequencing…

Short-term outcomes of enhanced recovery after surgery protocol in robotic-assisted McKeown esophagectomy for esophageal cancer: a single-center retrospective cohort study Open

Xia Xu, Jiajun Xiong, Zhijie Xu, Zhi Hu, Gu‐Ha Alai , et al. · 2023

Background This study aimed to evaluate the short-term outcomes of enhanced recovery after surgery (ERAS) protocol in perioperative robotic-assisted McKeown esophagectomy (RAME) among esophageal cancer patients. Methods For this retrospect…

[Mediating effect of self-efficacy on self-management ability and self-management behavior in patients with type 2 diabetes mellitus]. Open

Xi Zhang, Yi‐Dan Lin, Yong Jiang, L C Zhang, Mingqing Dong , et al. · 2023

Self-efficacy enhanced the effect of self-management ability on the behavior of the patients with type 2 diabetes, and this positive effect was more significant for the patients with shorter disease course. Targeted health education should…

Role of Lower Esophageal Squamous Cell Carcinoma Margin Location on Abdominal Lymph Node Metastasis Risk Open

Xia Zhong, Xue-Hua Tu, Gu‐Ha Alai, Ze‐Guo Zhuo, Peng Yao , et al. · 2023

Background: Different sites of esophageal cancer are accompanied by different regional lymph node metastasis (LNM) risks. We aimed to investigate the impact of a lower tumor margin on abdominal LNM risk. Methods: We enrolled patients who u…

Perioperative and oncological outcomes of uniportal versus three-port thoracoscopic segmentectomy for lung cancer: a propensity score matching analysis Open

Jian Zhou, Quan Zheng, Qiang Pu, Jiandong Mei, Lin Ma , et al. · 2023

Uniportal video-assisted thoracoscopic segmentectomy is proven to be safe and feasible, and the perioperative outcomes and oncological results were similar between the uniportal and three-port regimens.

Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery Open

Bin Jiang, Qunyou Tan, Bo Deng, Longyong Mei, Yi‐Dan Lin , et al. · 2022

Background The aim of this study was to evaluate the safety and effectiveness of robot‐assisted thymectomy (RAT) in large anterior mediastinal tumors (AMTs) (size ≥6 cm) compared with video‐assisted thymectomy (VAT) and open surgery. Metho…

Whether the start time of elective lung surgery impacts perioperative outcomes and cost? Open

Gu‐Ha Alai, Jianrong Hu, Zhijie Xu, Peng Yao, Xia Zhong , et al. · 2022

Background Fatigue and the long work hours of surgeons have attracted increasing concern in recent years. We aimed to explore whether starting time was associated with perioperative outcomes and cost for elective lung surgery. Methods A re…

Surgical Treatment for Esophageal Leiomyoma: 13 Years of Experience in a High-Volume Tertiary Hospital Open

Gu‐Ha Alai, Jianrong Hu, Yao Peng, Yi‐Dan Lin · 2022

Background Esophageal leiomyoma is the most common benign tumor in the esophagus. Thoracotomy and thoracoscopy are both elective for esophageal leiomyoma enucleation. This study aimed at presenting surgical experience in our center and exp…

Case Report: Not a Mediastinal Mass! a Ruptured Giant Coronary Aneurysm That Occurred in a Young Man Open

Peng Yao, Cheng Shen, Zhi-Jie Xu, Yi‐Dan Lin · 2022

Introduction Coronary artery aneurysm (CAA) is a localized coronary artery dilatation that exceeds 1. 5 times the diameter of a standard adjacent segment or the largest coronary vessel. When the expansion is > 2 cm, it is called a “gian…

Prognostic value of node skip metastasis on esophageal cancer: A systematic review and meta-analysis Open

Gu‐Ha Alai, Zhijie Xu, Peng Yao, Xia Zhong, Yucheng Wang , et al. · 2022

The association between NSM and prognosis of esophageal cancer remains controversial, though several studies have been conducted drawing their own conclusion. Therefore, we firstly carried out this meta-analysis aiming to explore the assoc…

Outcomes of lung-surgery patients suffered perioperative COVID-19: A systematic review of case series Open

Gu‐Ha Alai, Ning-Ying Ding, Yi‐Dan Lin · 2022

Coronavirus disease 2019 has spread widely all over the world since December 2019.It is known that lung is mainly targeting organ of the disease. however, outcome of lung-surgery patients who suffered Coronavirus disease 2019 remains uncle…

Whether Start Time of Elective Lung Surgery Impacts Perioperative Outcomes and Cost? Open

Gu‐Ha Alai, Jianrong Hu, Zhijie Xu, Peng Yao, Xia Zhong , et al. · 2021

Background Fatigue and long work hours of surgeons attracts increasing concerns in recent years. In clinical practice, most patients prefer to receiving surgery in the morning. So, we aimed to explore whether starting time is associated wi…

The Chinese consensus for surgical treatment of traumatic rib fractures 2021 (C-STTRF 2021) Open

Lingwen Kong, Guang-Bin Huang, Yunfeng Yi, Dingyuan Du, Xiangjun Bai , et al. · 2021

Pretreatment-assisted robot intrathoracic layered anastomosis: our exploration in Ivor-Lewis esophagectomy Open

Zhijie Xu, Ze‐Guo Zhuo, Tie-Niu Song, Gang Li, Gu‐Ha Alai , et al. · 2021

PRILA further visualizes and streamlines the process of minimal invasive intrathoracic EGA, thus ensuring the precise anastomosis. It could be considered as a feasible alternative for intrathoracic EGA in MIILE.

Safety profile of preoperative administration of low-molecular-weight heparin on minimally invasive lung cancer surgery: a randomized controlled trial Open

Gu‐Ha Alai, Ze‐Guo Zhuo, Gang Li, Tie-Niu Song, Zhijie Xu , et al. · 2021

Background Venous thromboembolism remains a common but preventable complication for cancerous lung surgical patients. Current guidelines recommend thromboprophylaxis for lung patients at high risk of thrombosis, while a consensus about spe…

Corrigendum to ‘Role of nodal skip metastasis in patients with mid-thoracic oesophageal squamous cell carcinoma: a propensity score matching study’ Open

Zhijie Xu, Ze‐Guo Zhuo, Tie-Niu Song, Gu‐Ha Alai, Xu Shen , et al. · 2021

Is the routine placement of a feeding jejunostomy during esophagectomy worthwhile?—a systematic review and meta-analysis Open

Xu Shen, Ze‐Guo Zhuo, Gang Li, Gu‐Ha Alai, Tie-Niu Song , et al. · 2021

The non-selective placement of a FJT during esophagectomy provides few benefits to the patients and may even increase the risk of postoperative complications. Therefore, an intraoperative FJT should be selectively prescribed, but not routi…

From McKeown to Ivor Lewis, the learning curve for thoracic lymphadenectomy over the first 100 robotic esophagectomy cases: a retrospective study Open

Ze‐Guo Zhuo, Gang Li, Tie-Niu Song, Gu‐Ha Alai, Xu Shen , et al. · 2021

Twenty-three cases were needed for an experienced surgical team to improve thoracic lymphadenectomy results using McKeown RAMIE. There was another learning phase during the transition from McKeown to Ivor Lewis esophagectomy. Importantly, …

Reply to Zhang <i>et al</i> Open

Zhijie Xu, Yi‐Dan Lin · 2021

Role of nodal skip metastasis in patients with mid-thoracic oesophageal squamous cell carcinoma: a propensity score matching study Open

Zhijie Xu, Ze‐Guo Zhuo, Tie-Niu Song, Gu‐Ha Alai, Xu Shen , et al. · 2020

OBJECTIVES Nodal skip metastasis (NSM) is a common phenomenon in mid-thoracic oesophageal squamous cell carcinoma (MT-OSCC); however, the prognostic implications of NSM in patients with MT-OSCC remain unclear. METHODS This retrospective st…

Predictors for the clinical benefit of anti-PD-1/PD-L1 therapy in advanced gastroesophageal cancer: a meta-analysis of clinical trials Open

Ze‐Guo Zhuo, Han‐Yu Deng, Tie-Niu Song, Gu‐Ha Alai, Xu Shen , et al. · 2020

The expression level of PD-L1, MSI, and ECOG performance status could be the predictors of achieving clinical benefit from anti-PD-1/anti-PD-L1 therapy in advanced gastroesophageal cancer.

The efficacy of ischemic conditioning in the prevention of gastroesophageal anastomotic complications: a meta-analysis Open

Ze‐Guo Zhuo, Xu Shen, Tie-Niu Song, Zhijie Xu, Gu‐Ha Alai , et al. · 2020

This meta-analysis proved that ischemic conditioning is a safe intervention that could reduce anastomotic complications effectively. Future randomized controlled clinical trials are needed to provide high-level evidence on this topic.

Fixed in the neck or pushed back into the thorax?—Impact of cervical anastomosis position on anastomosis healing Open

Jun Luo, Ze‐Guo Zhuo, Yunke Zhu, Han‐Yu Deng, Tie-Niu Song , et al. · 2020

The cervical anastomosis fixation, anastomosis mode, and hypertension are independent risk factors of gastroesophageal cervical anastomotic leakage.

Preoperative dilated esophagus is associated with a high risk of intrathoracic anastomotic leakage for patients with esophageal cancer Open

Ze‐Guo Zhuo, Gang Li, Han‐Yu Deng, Jun Luo, Gu‐Ha Alai , et al. · 2020

Patients with an IMPD over 1.79 mm are facing a higher risk of intrathoracic anastomosis leakage when applying the 25 mm circular stapler. Larger circular stapler or hand-sewn would be the better choice for these patients.

International expert consensus on the management of bleeding during VATS lung surgery Open

Lunxu Liu, Jiandong Mei, Jie He, Todd L. Demmy, Shugeng Gao , et al. · 2019

Intraoperative bleeding is the most crucial safety concern of video-assisted thoracic surgery (VATS) for a major pulmonary resection. Despite the advances in surgical techniques and devices, intraoperative bleeding is still not rare and re…

Ergonomic thoracic port design for video-assisted thoracoscopic minimally invasive esophagectomy and lymphadenectomy: a preliminary pilot study Open

Han‐Yu Deng, Xi Zheng, Gu‐Ha Alai, Ze‐Guo Zhuo, Gang Li , et al. · 2019

Our novel thoracoscopic port design and procedures of lymphadenectomy was proved to be feasible and ergonomic, which could be easily mastered by most of the thoracic surgeons.

Could Tumor Spread Through Air Spaces Identify Distinct Subgroup With Poor Prognosis in Lung Pleomorphic Carcinoma? Open

Tie-Niu Song, Yi‐Dan Lin · 2019

Application of full lateral decubitus position with cephalic parallel approach in robotic-assisted minimally invasive esophagectomy Open

Yunke Zhu, Lin Ma, Lunxu Liu, Yi‐Dan Lin · 2019

The newly designed full lateral position with cephalic-parallel approach, which makes the procedure highly convenient, is technically feasible for RAMIE.

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