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View article: Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction
Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction Open
Current treatment options for head and neck squamous cell carcinoma (HNSCC) are limited. Aspartate aminotransaminase (GOT1) plays an important role in cancer development but its role in HNSCC remains unknown. We combined proteomics and met…
View article: Direct Detection of Leptophobic Dark Matter with Electronic Collective Excitations
Direct Detection of Leptophobic Dark Matter with Electronic Collective Excitations Open
Some new-generation dark matter detection experiments are primarily designed to search for the dark matter-electron interactions, but they can also be utilized to probe models in which dark matter couples exclusively to nucleon via the qua…
View article: LAD-RAG: Layout-aware Dynamic RAG for Visually-Rich Document Understanding
LAD-RAG: Layout-aware Dynamic RAG for Visually-Rich Document Understanding Open
Question answering over visually rich documents (VRDs) requires reasoning not only over isolated content but also over documents' structural organization and cross-page dependencies. However, conventional retrieval-augmented generation (RA…
View article: Revisiting Multivariate Time Series Forecasting with Missing Values
Revisiting Multivariate Time Series Forecasting with Missing Values Open
Missing values are common in real-world time series, and multivariate time series forecasting with missing values (MTSF-M) has become a crucial area of research for ensuring reliable predictions. To address the challenge of missing data, c…
View article: Comprehensive evaluation of critical-size calvarial defect in athymic rat model
Comprehensive evaluation of critical-size calvarial defect in athymic rat model Open
The critical size defect (CSD), which defines the threshold beyond which spontaneous healing fails, serves as a foundational tool in bone regeneration research. This study investigated calvarial CSDs in an athymic rat model to refine the d…
View article: TheInterplayofStructuralStiffnessandMechanicalVibrationsinMulti-LevelConstructions
TheInterplayofStructuralStiffnessandMechanicalVibrationsinMulti-LevelConstructions Open
This paper explores the structural dynamics and vibration of a model can be used in varying types of structures. Structural dynamics has a wide range of applications like civil engineering, mechanical engineering, transportation, aerospace…
View article: MuseRAG++: A Deep Retrieval-Augmented Generation Framework for Semantic Interaction and Multi-Modal Reasoning in Virtual Museums
MuseRAG++: A Deep Retrieval-Augmented Generation Framework for Semantic Interaction and Multi-Modal Reasoning in Virtual Museums Open
Virtual museums offer new opportunities for cultural heritage engagement by enabling interactive and personalized experiences beyond physical constraints. However, existing dialogue systems struggle to provide semantically adaptive, factua…
View article: Elucidating the mechanism of dibutyl phthalate on Alzheimer's disease through network toxicology, molecular docking and validation in mouse neuroblastoma cells
Elucidating the mechanism of dibutyl phthalate on Alzheimer's disease through network toxicology, molecular docking and validation in mouse neuroblastoma cells Open
Dibutyl phthalate (DBP), a widely used plasticizer, has been suggested to be neurotoxic. We aim to explore possible molecular mechanisms of DBP on Alzheimer's disease (AD) using a combined approach of network toxicology, molecular docking …
View article: The impact of prepregnancy overweight and obesity on newborn glucose-lipid metabolism: An observational study
The impact of prepregnancy overweight and obesity on newborn glucose-lipid metabolism: An observational study Open
This study seeks to explore the association between maternal prepregnancy excessive weight and metabolic changes in glucose and lipids during early gestation, with a particular focus on its implications for neonatal metabolic health. The r…
View article: Synergistic catalytic mechanism and performance regulation strategies between nanoparticles/clusters and single-atom sites
Synergistic catalytic mechanism and performance regulation strategies between nanoparticles/clusters and single-atom sites Open
In recent years, nanoparticle/cluster catalysts and single-atom catalysts (SACs) have achieved remarkable advancements in catalytic applications, particularly in the energy and environmental sectors. SACs excel in catalysis through atomica…
View article: Seamless finer-resolution soil moisture from the synergistic merging of the FengYun-3 satellite series
Seamless finer-resolution soil moisture from the synergistic merging of the FengYun-3 satellite series Open
In the last years, more satellites with microwave imagers have been launched, making more observations available to obtain soil moisture estimates globally. China's endeavour has resulted in the launch of the FengYun (FY) passive microwave…
View article: Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress
Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress Open
Prenatal environmental stress damages fetal testicular development, leading to male infertility. However, the precise mechanisms underlying the impact of gestational environmental stress on fetal testicular development require further inve…
View article: Why does India still face challenges in addressing national development issues despite nearly seven decades of democratization?
Why does India still face challenges in addressing national development issues despite nearly seven decades of democratization? Open
India's seven-decade-long democratic journey has sustained political stability yet struggled to resolve persistent governance challenges, including economic disparities and gender inequality. This study employs a postcolonial framework and…
View article: Modulatory effects of polyherbal mixture on the immuno-antioxidant capacity and intestinal health of chicks infected with Escherichia coli O78
Modulatory effects of polyherbal mixture on the immuno-antioxidant capacity and intestinal health of chicks infected with Escherichia coli O78 Open
View article: The association between occupational noise exposure and hearing loss among petrochemical enterprise workers in Hainan, South China
The association between occupational noise exposure and hearing loss among petrochemical enterprise workers in Hainan, South China Open
To investigate the current situation of hearing loss and the associations of occupational noise exposure with hearing loss in petrochemical enterprise workers. This was a cross-sectional study that employed cluster sampling methods, and 95…
View article: Author response: Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study
Author response: Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study Open
View article: Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study
Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study Open
Background: Biological aging exhibits heterogeneity across multi-organ systems. However, it remains unclear how is lifestyle associated with overall and organ-specific aging and which factors contribute most in Southwest China. Methods: Th…
View article: An Enhanced Local Optimization Algorithm for GNSS Shadow Matching in Mobile Phones
An Enhanced Local Optimization Algorithm for GNSS Shadow Matching in Mobile Phones Open
In the context of mobile phones, the local optimal global navigation satellite systems (GNSS) shadow matching algorithm, which is based on the urban three-dimensional model, can effectively reduce the error of GNSS pseudo-range single-poin…
View article: Changes in drinking levels and metabolic dysfunction-associated steatotic liver disease: a longitudinal study from the China multi-ethnic cohort study
Changes in drinking levels and metabolic dysfunction-associated steatotic liver disease: a longitudinal study from the China multi-ethnic cohort study Open
In the less developed regions of China, sustained moderate drinking was associated with the risk of MASLD compared with sustained non-drinking. Increased drinking showed a trend towards a higher risk of MASLD. This study can inform drinkin…
View article: Parity considerations in the number of overlined parts and non-overlined parts
Parity considerations in the number of overlined parts and non-overlined parts Open
Recently, Chen, He, Hu and Xie considered the number of non-overlined (resp. overlined) parts of size greater than or equal to the size of the smallest overlined (resp. non-overlined) part in an overpartition. In this article, we will stud…
View article: Fast and Intelligent Proportional–Integral–Derivative (PID) Attitude Control of Quadrotor and Dual-Rotor Coaxial Unmanned Aerial Vehicles (UAVs) Based on All-True Composite Motion
Fast and Intelligent Proportional–Integral–Derivative (PID) Attitude Control of Quadrotor and Dual-Rotor Coaxial Unmanned Aerial Vehicles (UAVs) Based on All-True Composite Motion Open
The construction of a six-degree-of-freedom (6-DOF) model for the composite motion of the actual mechanical structure (defined as an all-true composite motion model) of unmanned aerial vehicles (UAVs) is a prerequisite for achieving stable…
View article: Production of protons and light nuclei in <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>Au</mml:mi><mml:mo>+</mml:mo><mml:mi>Au</mml:mi></mml:math> collisions at <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>N</mml:mi><mml:mi>N</mml:mi></mml:mrow></mml:msub></mml:msqrt><mml:mspace width="0.16em"/><mml:mo>=</mml:mo><mml:mspace width="0.16em"/><mml:mn>3</mml:mn></mml:mrow></mml:math> GeV with the STAR detector
Production of protons and light nuclei in collisions at GeV with the STAR detector Open
We report the systematic measurement of protons and light nuclei production in Au +Au collisions at $\\sqrt{s{NN}}$ = 3GeV by the STAR experiment at the Relativistic Heavy Ion Collider (RHIC). The transverse momentum (pT) spectr…
View article: Author response: Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study
Author response: Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study Open
View article: Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study
Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study Open
Background Biological aging exhibits heterogeneity across multi organ systems. However, it remains unclear how is lifestyle associated with overall and organ-specific aging and which factors contribute most in Southwest China. Objective To…
View article: First results of a newly-built hard-X-ray/soft-Gamma spectrometer imaging system: on the aspect of plasma disruptions
First results of a newly-built hard-X-ray/soft-Gamma spectrometer imaging system: on the aspect of plasma disruptions Open
A new Hard X-ray and soft gamma-ray spectrometer imaging System (HXS) has been built for the 2-Dimensional measurements of plasma emitted photons on the Experimental Advanced Superconducting Tokamak (EAST). The system uses a 2-D Cadmium Zi…
View article: Design and Experimentation of the Millet Combine Harvester Header
Design and Experimentation of the Millet Combine Harvester Header Open
To address the issue of header loss in millet combine harvesters, a double-chain millet harvester header was designed based on the principles of contact mechanics and tribology. Key component parameters of the header were determined, with …
View article: Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study
Lifestyles and their relative contribution to biological aging across multiple-organ systems: Change analysis from the China Multi-Ethnic Cohort study Open
Background: Biological aging exhibits heterogeneity across multi-organ systems. However, it remains unclear how is lifestyle associated with overall and organ-specific aging and which factors contribute most in Southwest China. Methods: Th…
View article: Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study
Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study Open
Background Biological aging exhibits heterogeneity across multi organ systems. However, it remains unclear how is lifestyle associated with overall and organ-specific aging and which factors contribute most in Southwest China. Objective To…
View article: Multi-level Monte-Carlo Gradient Methods for Stochastic Optimization with Biased Oracles
Multi-level Monte-Carlo Gradient Methods for Stochastic Optimization with Biased Oracles Open
We consider stochastic optimization when one only has access to biased stochastic oracles of the objective and the gradient, and obtaining stochastic gradients with low biases comes at high costs. This setting captures various optimization…
View article: Plin4 exacerbates cadmium-decreased testosterone level via inducing ferroptosis in testicular Leydig cells
Plin4 exacerbates cadmium-decreased testosterone level via inducing ferroptosis in testicular Leydig cells Open