Ying Jiang
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View article: Elevated Antibacterial Activity with Decreased Cytotoxicity of a Polygalacturonic + Caprylic Acid Wound Ointment Compared with Hypochlorous Acid in a Three-Dimensional Wound Biofilm Model
Elevated Antibacterial Activity with Decreased Cytotoxicity of a Polygalacturonic + Caprylic Acid Wound Ointment Compared with Hypochlorous Acid in a Three-Dimensional Wound Biofilm Model Open
Introduction: Natural, plant-based agents are alternatives to antibiotics and antiseptics in treating bacterially colonized wounds and potentially offer an antimicrobial activity without cytotoxicity. In this study, we used a three-dimensi…
View article: Impact of Teduglutide on Pediatric Short Bowel Syndrome: Protocol for a Systematic Review and Trial Sequential Meta-Analysis
Impact of Teduglutide on Pediatric Short Bowel Syndrome: Protocol for a Systematic Review and Trial Sequential Meta-Analysis Open
Background Although studies have evaluated the safety and efficacy of GLP drugs in adult patients with short bowel syndrome, pediatric applications remain contentious due to developmental divergences in drug response and safety profiles. T…
View article: The Effect of Academic Organizational Climate Perception on Knowledge Sharing Behavior of Postgraduate Students in Universities in Jiangxi Province, China
The Effect of Academic Organizational Climate Perception on Knowledge Sharing Behavior of Postgraduate Students in Universities in Jiangxi Province, China Open
This study, grounded in Self-Determination Theory, investigated the mechanism through which the perception of academic organizational climate from postgraduate student influences their knowledge sharing behavior, particularly paying attent…
View article: Fosaprepitant for the prevention of multiple-day cisplatin chemotherapy-induced nausea and vomiting: a prospective randomized controlled study
Fosaprepitant for the prevention of multiple-day cisplatin chemotherapy-induced nausea and vomiting: a prospective randomized controlled study Open
View article: ROS confer resistance to 3TC in p53 mutant colorectal cancer by promoting autophagy and ER stress
ROS confer resistance to 3TC in p53 mutant colorectal cancer by promoting autophagy and ER stress Open
Colorectal cancer (CRC) is among the most frequently diagnosed cancers globally. Lamivudine (3 TC), a nucleoside reverse transcriptase inhibitor (NRTI) commonly used for treating Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HB…
View article: Risk factors for catheter-related bloodstream infections in a high-risk cancer patient population
Risk factors for catheter-related bloodstream infections in a high-risk cancer patient population Open
To identify risk factors for catheter-related bloodstream infections (CRBSI) in cancer patients, we compared 200 CRBSI cases to 400 controls. Neutropenia, transplants, multiple catheters, blood products, and basilic/cephalic PICCs increase…
View article: Outcomes and Risk Factors for Influenza and Respiratory Syncytial Virus Lower Respiratory Tract Infections and Mortality in Patients With Lymphoma or Multiple Myeloma: A 7-Year Retrospective Cohort Study
Outcomes and Risk Factors for Influenza and Respiratory Syncytial Virus Lower Respiratory Tract Infections and Mortality in Patients With Lymphoma or Multiple Myeloma: A 7-Year Retrospective Cohort Study Open
Background Respiratory viral infection (RVI) is a significant complication in patients with hematologic malignancies. While risk factors of lower respiratory tract infections (LRIs) and mortality have been studied in allogeneic hematopoiet…
View article: Organization Capital, Digital Transformation and Executives’ Excess compensation
Organization Capital, Digital Transformation and Executives’ Excess compensation Open
This study explores the relationship between organizational capital and executive excess compensation, alongside the moderating role of digital transformation on this relationship. Using a dataset from China covering the period from 2011 t…
View article: The Antifungal Activity of a Polygalacturonic and Caprylic Acid Ointment in an In Vitro, Three-Dimensional Wound Biofilm Model
The Antifungal Activity of a Polygalacturonic and Caprylic Acid Ointment in an In Vitro, Three-Dimensional Wound Biofilm Model Open
Candida colonization and biofilms are significant contributors to impaired wound healing. Consequently, improved treatments are needed to eradicate Candida biofilms in wounds. Wounds present complex biofilm extracellular matrix environment…
View article: Decreased Frequency and Improved Outcomes in Invasive Aspergillosis Caused by Aspergillus terreus After the Introduction of Anti-Mold Azole Agents: A 30-Year Study at a Tertiary Cancer Center
Decreased Frequency and Improved Outcomes in Invasive Aspergillosis Caused by Aspergillus terreus After the Introduction of Anti-Mold Azole Agents: A 30-Year Study at a Tertiary Cancer Center Open
Invasive aspergillosis (IA) is a significant cause of morbidity and mortality in patients with hematological malignancy (HM) and hematopoietic stem cell transplant (HSCT) recipients. Aspergillus terreus is associated with worse outcomes th…
View article: P-1045. Decreasing Frequency of Invasive Aspergillus due to <i>Aspergillus terreus</i> Coinciding with the Introduction of Anti-Mold Azole Prophylaxis: A 30 Year Study of Invasive Aspergillosis at a Tertiary Cancer Center
P-1045. Decreasing Frequency of Invasive Aspergillus due to <i>Aspergillus terreus</i> Coinciding with the Introduction of Anti-Mold Azole Prophylaxis: A 30 Year Study of Invasive Aspergillosis at a Tertiary Cancer Center Open
Background Invasive aspergillosis (IA) is a significant cause of morbidity and mortality in patients with haematological malignancy (HM) patients and hematopoietic stem cell transplant (HSCT) recipients. A. terreus is well known to be more…
View article: P-1895. Outpatient Parenteral Antimicrobial Therapy Multidisciplinary Partnership Reduces Readmissions and Emergency Center Visits in a Comprehensive Cancer Center
P-1895. Outpatient Parenteral Antimicrobial Therapy Multidisciplinary Partnership Reduces Readmissions and Emergency Center Visits in a Comprehensive Cancer Center Open
Background Outpatient parenteral antimicrobial therapy (OPAT) programs have reduced readmissions without impacting emergency center (EC) visits. Our initial pilot OPAT program improved laboratory monitoring without decreasing readmissions …
View article: P-226. Assessing the Risk Factors for Catheter Related Bloodstream Infections (CRBSI) among Cancer Patients with Long Term Central Venous Catheters (LCVC) for Implementing Preventive Interventions
P-226. Assessing the Risk Factors for Catheter Related Bloodstream Infections (CRBSI) among Cancer Patients with Long Term Central Venous Catheters (LCVC) for Implementing Preventive Interventions Open
Background Catheter Related Bloodstream Infection (CRBSI) remains a leading cause of morbidity, mortality, and escalating costs in cancer patients with LCVC despite advancements in medical care and the implementation of BSI bundle. Several…
View article: P-1069. Comparative Antibacterial Activity of Hypochlorous and Polygalacturonic + Caprylic Acids in an <i>In Vitro</i> Wound Biofilm Model
P-1069. Comparative Antibacterial Activity of Hypochlorous and Polygalacturonic + Caprylic Acids in an <i>In Vitro</i> Wound Biofilm Model Open
Background Therapeutic agents which impart minimal inflammatory responses are needed to disinfect microbially contaminated chronic wounds. Polygalacturonic + caprylic (PG+CAP) and hypochlorous (HOCl) acids have been shown to be well tolera…
View article: P-1068. Inhibitory Effect of EDTA on Metallo β-Lactamase Producing Gram-Negative Pathogens Recovered from Cancer Patients with Bloodstream Infections
P-1068. Inhibitory Effect of EDTA on Metallo β-Lactamase Producing Gram-Negative Pathogens Recovered from Cancer Patients with Bloodstream Infections Open
Background The spread of metallo β-lactamase (Mβ-L) producing Gram negative pathogens is an important worldwide medical problem. It presents the broadest-spectrum β-lactam resistance of all carbapenemase-producing organisms leaving few rem…
View article: P-1114. Comparative in vitro Microbiologic Study of Two Plant-Based Wound Ointments
P-1114. Comparative in vitro Microbiologic Study of Two Plant-Based Wound Ointments Open
Background Plant-based wound ointments can provide antimicrobial prophylaxis without the inflammation and cytotoxicity associated with common antiseptic ointments that can inhibit closure of chronic wounds. Inula Viscosa (IV) is a plant wi…
View article: 297. Comparative In Vitro Microbiologic Activity of Two Antimicrobial Intravenous Connectors
297. Comparative In Vitro Microbiologic Activity of Two Antimicrobial Intravenous Connectors Open
Background Intravenous (IV) connectors are ubiquitous access junctions in vascular access circuits. In accessing IV connectors (IVCs) for infusions, they become vulnerable to microbial contamination and colonization. Antimicrobial IVCs are…
View article: Clinical analysis of different intestinal reconstruction methods after primary cytoreductive surgery combined with rectal resection for advanced ovarian cancer
Clinical analysis of different intestinal reconstruction methods after primary cytoreductive surgery combined with rectal resection for advanced ovarian cancer Open
Objective To compare different intestinal reconstruction methods after intestinal resection for advanced ovarian malignancy. Methods Retrospective data of patients with advanced ovarian malignancy were collected and then assigned into thre…
View article: Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study
Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study Open
View article: Maternal serum Numb in the first trimester of pregnancy as a biomarker for early prediction of pre‐eclampsia: A prospective cohort study
Maternal serum Numb in the first trimester of pregnancy as a biomarker for early prediction of pre‐eclampsia: A prospective cohort study Open
Objective Early identification of women at risk of developing pre‐eclampsia is beneficial as it allows for timely intervention strategies. This study aimed to evaluate the potential of serum Numb in the first trimester as a biomarker for e…
View article: Dietary Inflammatory Index is intensity-dependently associated with the Bone Mineral Density at the Lumbar Spine: A Cross- Sectional NHANES Study from 2007 to 2020
Dietary Inflammatory Index is intensity-dependently associated with the Bone Mineral Density at the Lumbar Spine: A Cross- Sectional NHANES Study from 2007 to 2020 Open
Background Bone mineral density (BMD) is a tool to assess bone health. Dietary inflammation index (DII) is an index to reflect the inflammatory effect of a diet. Even though the association between DII and BMD have been extensively studied…
View article: Procalcitonin Level Monitoring in Antibiotic De-Escalation and Stewardship Program for Patients with Cancer and Febrile Neutropenia
Procalcitonin Level Monitoring in Antibiotic De-Escalation and Stewardship Program for Patients with Cancer and Febrile Neutropenia Open
Objective: Serial procalcitonin (PCT) monitoring has been adopted to supplement clinical judgement and help guide antibiotic therapy as part of antimicrobial stewardship programs. PCT levels peak 24 to 48 h after infection onset and declin…
View article: Cytomegaloviral Infections in Recipients of Chimeric Antigen Receptor T-Cell Therapy: An Observational Study With Focus on Oncologic Outcomes
Cytomegaloviral Infections in Recipients of Chimeric Antigen Receptor T-Cell Therapy: An Observational Study With Focus on Oncologic Outcomes Open
Background Patients with B-cell lymphoma and acute lymphoblastic leukemia (ALL) who receive chimeric antigen receptor T-cell (CAR-T) therapy may experience clinically significant cytomegalovirus infection (CS-CMVi). However, risk factors f…
View article: Predicting COVID 19–Associated Pulmonary Aspergillosis Risk in Low- and Middle-Income Countries: A Matched Case-Control Study
Predicting COVID 19–Associated Pulmonary Aspergillosis Risk in Low- and Middle-Income Countries: A Matched Case-Control Study Open
Background Coronavirus disease 2019 (COVID-19)–associated pulmonary aspergillosis (CAPA) is a life-threatening fungal infection. Studies focusing on CAPA in low- and middle-income countries are limited. Methods This retrospective matched c…
View article: A prospective randomized controlled clinical trial investigating the efficacy of low-dose olanzapine in preventing nausea and vomiting associated with oxaliplatin-based and irinotecan-based chemotherapy
A prospective randomized controlled clinical trial investigating the efficacy of low-dose olanzapine in preventing nausea and vomiting associated with oxaliplatin-based and irinotecan-based chemotherapy Open
View article: The modern face of esophageal candidiasis in an oncology center: Correlating clinical manifestations, endoscopic grade, and pathological data in 323 contemporary cancer patients
The modern face of esophageal candidiasis in an oncology center: Correlating clinical manifestations, endoscopic grade, and pathological data in 323 contemporary cancer patients Open
EC was predominantly encountered in patients with solid tumors. One-third of EC patients were asymptomatic, challenging traditional symptom-based diagnosis. The development of integrated clinicopathological scoring systems could further gu…
View article: <i>In vitro</i> activity of cefepime/taniborbactam and comparator agents against Gram-negative bacterial bloodstream pathogens recovered from patients with cancer
<i>In vitro</i> activity of cefepime/taniborbactam and comparator agents against Gram-negative bacterial bloodstream pathogens recovered from patients with cancer Open
Background Taniborbactam is a β-lactamase inhibitor that, when combined with cefepime, may offer a potential treatment option for patients with serious and resistant Gram-negative bacterial (GNB) pathogens. Objectives This study evaluated …
View article: Comparing Molnupiravir to Nirmatrelvir/Ritonavir (Paxlovid) in the Treatment of Mild-to-Moderate COVID-19 in Immunocompromised Cancer Patients
Comparing Molnupiravir to Nirmatrelvir/Ritonavir (Paxlovid) in the Treatment of Mild-to-Moderate COVID-19 in Immunocompromised Cancer Patients Open
Background: Nirmatrelvir/Ritonavir has been shown to reduce the risk of COVID-19 progression by 88% compared to placebo, while Molnupiravir reduced it by 31%. However, these two agents have not been compared head-to-head. We therefore comp…
View article: Adjunct Terbinafine in Patients With Leukemia and Invasive Fusariosis With Skin Lesions: Discordance Between Responses of Skin Lesions and Systemic Outcomes
Adjunct Terbinafine in Patients With Leukemia and Invasive Fusariosis With Skin Lesions: Discordance Between Responses of Skin Lesions and Systemic Outcomes Open
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View article: VR-GS: A Physical Dynamics-Aware Interactive Gaussian Splatting System in Virtual Reality
VR-GS: A Physical Dynamics-Aware Interactive Gaussian Splatting System in Virtual Reality Open
As consumer Virtual Reality (VR) and Mixed Reality (MR) technologies gain momentum, there's a growing focus on the development of engagements with 3D virtual content. Unfortunately, traditional techniques for content creation, editing, and…