Explanipedia

Verification of cuproptosis-related diagnostic model associated with immune infiltration in rheumatoid arthritis Open

Mingyang Jiang, Kaicheng Liu, Shenyi Lu, Yue Qiu, Xiaochong Zou , et al. · 2023

Background Rheumatoid arthritis (RA) is a chronic autoimmune disease closely related to inflammation. Cuproptosis is a newly discovered unique type of cell death, and it has been found that it may play an essential role in the occurrence a…

Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1 Open

Mingyang Jiang, Yiji Jike, Kaicheng Liu, Fu Gan, Ke Zhang , et al. · 2023

Consensus Clustering and Survival-Related Genes of Cuproptosis in Cutaneous Melanoma Open

Wentao Qin, Fu Gan, Yiji Jike, Mingyang Jiang, Ang Li · 2023

As a highly malignant tumor, the morbidity and mortality of cutaneous melanoma (CM) are increasing year by year. A novel type of cell death connected to mitochondrial metabolism is called cuproptosis. Cuproptosis regulates tumor biological…

Identification of Potential Therapeutic Target Genes in Osteoarthritis Open

Yang Hu, Yinteng Wu, Fu Gan, Mingyang Jiang, Dongxu Chen , et al. · 2022

Objective. Osteoarthritis (OA), also known as joint failure, is characterized by joint pain and, in severe cases, can lead to loss of joint function in patients. Immune-related genes and immune cell infiltration play a crucial role in OA d…

A Risk-Scoring Model Based on Evaluation of Ferroptosis-Related Genes in Osteosarcoma Open

Mingyang Jiang, Zifan Wang, Xiaoyu He, Yang Hu, Mingjing Xie , et al. · 2022

Background. Osteosarcoma (OS) is a bone malignancy frequently seen in pediatrics and has high mortality and incidence. Ferroptosis is an important cell death process in regulating the apoptosis and invasion of tumor cells, so constructing …

Risk score model of autophagy-related genes in osteosarcoma Open

Mingyang Jiang, Dalang Fang, Xiaoyu He, Jie Huang, Yang Hu , et al. · 2022

We constructed a risk score model related to autophagy of OS, explored the diagnostic value of ARGs, and present possible therapeutic targets.

[Retracted] Verification of Ferroptosis Subcluster‐Associated Genes Related to Osteosarcoma and Exploration of Immune Targeted Therapy Open

Mingyang Jiang, Yiji Jike, Fu Gan, Jia Li, Yang Hu , et al. · 2022

Background . Despite tremendous advances in treating osteosarcoma (OS), the survival rates of patients have failed to improve dramatically over the past decades. Ferroptosis, a newly discovered iron‐dependent type of regulated cell death, …

Risk score model of autophagy-related genes in osteosarcoma Open

Wentao Qin, Mingyang Jiang, Yang Hu, Mingjing Xie, Yiji Jike , et al. · 2021

Background Osteosarcoma (OS) is the most common primary malignancy in children and adolescents, with a high mortality and disability rate. Autophagy plays an important role in the regulation of apoptosis, invasion and metastasis of tumor c…

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