Yikai Xu
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View article: Multimodal radiopathomics approach for predictions of prognosis and immunotherapy response in patients with gastric cancer: a multicohort retrospective study
Multimodal radiopathomics approach for predictions of prognosis and immunotherapy response in patients with gastric cancer: a multicohort retrospective study Open
Background: Current TNM staging systems insufficiently predict individual prognosis and chemotherapy response in gastric cancer (GC). We aimed to develop and validate a radiopathomics signature (RPS) integrating computed tomography (CT) an…
View article: Research on TOFD testing technique for nickel-based alloy piping in reactor coolant systems of nuclear power plants
Research on TOFD testing technique for nickel-based alloy piping in reactor coolant systems of nuclear power plants Open
As existing nuclear power plants in China gradually transition from the RSEM standards to the ASME standards, additional in-service inspection items have been introduced, including nickel-based alloy tubing and welds in the reactor coolant…
View article: Histogram analysis of multiple mathematical diffusion-weighted imaging models for preoperative prediction of Ki-67 expression in hepatocellular carcinoma
Histogram analysis of multiple mathematical diffusion-weighted imaging models for preoperative prediction of Ki-67 expression in hepatocellular carcinoma Open
Objective To explore whether a combination of clinico-radiological factors and histogram parameters based on monoexponential, biexponential, and stretched exponential models derived from the whole-tumor volume on diffusion-weighted imaging…
View article: Ultra-low dose dual-layer detector spectral CT for pulmonary nodule screening: image quality and diagnostic performance
Ultra-low dose dual-layer detector spectral CT for pulmonary nodule screening: image quality and diagnostic performance Open
Objectives To investigate the image quality and diagnostic performance with ultra-low dose dual-layer detector spectral CT (DLSCT) by various reconstruction techniques for evaluation of pulmonary nodules. Materials and methods Between Apri…
View article: Diffusion-T2 correlated spectroscopy imaging to explore possible placental composition changes over gestation
Diffusion-T2 correlated spectroscopy imaging to explore possible placental composition changes over gestation Open
Background Placenta plays a vital role for fetal growth and development during pregnancy. Currently, antenatal noninvasive imaging techniques to directly evaluate placental function remains challenge. Diffusion-T2 correlated spectroscopy i…
View article: Analysis of the risk factors of the radiation-induced encephalopathy in nasopharyngeal carcinoma: A retrospective cohort study
Analysis of the risk factors of the radiation-induced encephalopathy in nasopharyngeal carcinoma: A retrospective cohort study Open
To analyze the related factors of radiation-induced encephalopathy in nasopharyngeal carcinoma (NPC) to identify the risk factors and their clinical significance. This retrospective cohort study included 707 NPC patients. They had undergon…
View article: Non-invasive tumor microenvironment evaluation and treatment response prediction in gastric cancer using deep learning radiomics
Non-invasive tumor microenvironment evaluation and treatment response prediction in gastric cancer using deep learning radiomics Open
The tumor microenvironment (TME) plays a critical role in disease progression and is a key determinant of therapeutic response in cancer patients. Here, we propose a noninvasive approach to predict the TME status from radiological images b…
View article: [Three-dimensional pseudo-continuous arterial spin labeling for evaluation of cerebral hemodynamic changes after revascularization in adult patients with moyamoya disease].
[Three-dimensional pseudo-continuous arterial spin labeling for evaluation of cerebral hemodynamic changes after revascularization in adult patients with moyamoya disease]. Open
3D-pCASL is an valuable means for noninvasive monitoring of hemodynamic changes after revascularization in adult patients with moyamoya disease without the use of contrast agent.
View article: Facile Synthesis of Weakly Ferromagnetic Organogadolinium Macrochelates‐Based T<sub>1</sub>‐Weighted Magnetic Resonance Imaging Contrast Agents
Facile Synthesis of Weakly Ferromagnetic Organogadolinium Macrochelates‐Based T<sub>1</sub>‐Weighted Magnetic Resonance Imaging Contrast Agents Open
To surmount the major concerns of commercial small molecule Gd chelates and reported Gd‐based contrast agents (GBCAs) for magnetic resonance imaging (MRI), a new concept of organogadolinium macrochelates (OGMCs) constructed from the coordi…
View article: 1284 Biology-guided deep learning predicts prognosis and cancer immunotherapy response
1284 Biology-guided deep learning predicts prognosis and cancer immunotherapy response Open
Background Substantial progress has been made in using deep learning for cancer detection and diagnosis in medical images.1-10 However, a significant hurdle for clinical translation of current data-driven deep learning models is…
View article: Biodegradable and biocompatible exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging of tumors
Biodegradable and biocompatible exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging of tumors Open
View article: Comparative study of diffuse midline glioma and glioblastoma: Magnetic Resonance Imaging (MRI) in the characteristics and demography
Comparative study of diffuse midline glioma and glioblastoma: Magnetic Resonance Imaging (MRI) in the characteristics and demography Open
Introduction: Diffuse midline glioma and glioblastoma are classified as grade IV CNS tumors (WHO). The entity ‘diffuse midline glioma, H3 K27 mutant’ was introduced in the 4th revised edition of the 2016 WHO classification of brain tumors;…
View article: Association of Habitual Glucosamine Use with Risk of Dementia: Prospective Study in UK Biobank
Association of Habitual Glucosamine Use with Risk of Dementia: Prospective Study in UK Biobank Open
View article: Evaluation of microvascular invasion of hepatocellular carcinoma using whole-lesion histogram analysis with the stretched-exponential diffusion model
Evaluation of microvascular invasion of hepatocellular carcinoma using whole-lesion histogram analysis with the stretched-exponential diffusion model Open
Objectives: To evaluate the potential role of histogram analysis of stretched exponential model (SEM) through whole-tumor volume for preoperative prediction of microvascular invasion (MVI) in single hepatocellular carcinoma (HCC). Methods:…
View article: A fully automatic artificial intelligence–based CT image analysis system for accurate detection, diagnosis, and quantitative severity evaluation of pulmonary tuberculosis
A fully automatic artificial intelligence–based CT image analysis system for accurate detection, diagnosis, and quantitative severity evaluation of pulmonary tuberculosis Open
View article: Cross-Cultural Adaptation and Validation of the Emotional Inhibition Scale in a Chinese Cancer Sample
Cross-Cultural Adaptation and Validation of the Emotional Inhibition Scale in a Chinese Cancer Sample Open
The Emotional Inhibition Scale (EIS) is a brief measure based on a four-factor model with documented validity in a mood disorder sample that may be useful for assessing emotional inhibition in patient populations, such as individuals with …
View article: An Optimized Integrin α6-Targeted Magnetic Resonance Probe for Molecular Imaging of Hepatocellular Carcinoma in Mice
An Optimized Integrin α6-Targeted Magnetic Resonance Probe for Molecular Imaging of Hepatocellular Carcinoma in Mice Open
These findings suggest the potential application of this integrin α6-targeted MR probe for the detection of HCC, particularly for small HCC.
View article: Preoperative Gadoxetic Acid-Enhanced MRI Based Nomogram Improves Prediction of Early HCC Recurrence After Ablation Therapy
Preoperative Gadoxetic Acid-Enhanced MRI Based Nomogram Improves Prediction of Early HCC Recurrence After Ablation Therapy Open
Purpose This study aimed to identify preoperative gadoxetic acid-enhanced MRI features and establish a nomogram for predicting early recurrence (≤ 2 years) of hepatocellular carcinoma (HCC) after ablation therapy. Methods A total of 160 pa…
View article: A Fully Automatic AI-based CT Image Analysis System for Accurate Detection, Diagnosis, and Quantitative Severity Evaluation of Pulmonary Tuberculosis
A Fully Automatic AI-based CT Image Analysis System for Accurate Detection, Diagnosis, and Quantitative Severity Evaluation of Pulmonary Tuberculosis Open
Background: Accurate and rapid diagnosis of pulmonary tuberculosis (TB) plays a crucial role in timely prevention and appropriate medical treatment to the disease. This study aims to develop and evaluate an artificial intelligence (AI)-bas…
View article: Cycle-Consistent Generative Adversarial Network: Effect on Radiation Dose Reduction and Image Quality Improvement in Ultralow-Dose CT for Evaluation of Pulmonary Tuberculosis
Cycle-Consistent Generative Adversarial Network: Effect on Radiation Dose Reduction and Image Quality Improvement in Ultralow-Dose CT for Evaluation of Pulmonary Tuberculosis Open
The optimized CycleGAN technique may allow the synthesis of diagnostically acceptable images from ULDCT of the chest for the evaluation of pulmonary tuberculosis.
View article: Meta-analysis of the Value of Cardiac Nuclear Magnetic Resonance in the Diagnosis of Viral Myocarditis
Meta-analysis of the Value of Cardiac Nuclear Magnetic Resonance in the Diagnosis of Viral Myocarditis Open
To evaluate the diagnostic value of cardiac magnetic resonance imaging (MRI) in viral myocarditis by meta-analysis.PubMed, EMbase, Cochrane, Web of Science, China National Knowledge Infrastructure (CNKI, China) Wanfang Databases were searc…
View article: Residual convolutional neural network for predicting response of transarterial chemoembolization in hepatocellular carcinoma from CT imaging
Residual convolutional neural network for predicting response of transarterial chemoembolization in hepatocellular carcinoma from CT imaging Open
View article: Overexpression of LIMD2 promotes the progression of non‑small cell lung cancer
Overexpression of LIMD2 promotes the progression of non‑small cell lung cancer Open
LIM domain containing 2 (LIMD2) is a small LIM-only protein that has been demonstrated to promote tumor progression; however, the expression and function of LIMD2 in non-small cell lung cancer (NSCLC) has not previously been reported. In t…
View article: RETRACTED ARTICLE: Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy
RETRACTED ARTICLE: Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy Open
Background It is very difficult to predict the early response to NAC only on the basis of change in tumor size. ADC value derived from DWI promises to be a valuable parameter for evaluating the early response to treatment. This study aims …
View article: Radiomics signature of computed tomography imaging for prediction of survival and chemotherapeutic benefits in gastric cancer
Radiomics signature of computed tomography imaging for prediction of survival and chemotherapeutic benefits in gastric cancer Open
View article: A radiomics nomogram for preoperative prediction of microvascular invasion risk in hepatitis B virus-related hepatocellular carcinoma
A radiomics nomogram for preoperative prediction of microvascular invasion risk in hepatitis B virus-related hepatocellular carcinoma Open
The radiomics nomogram, as a noninvasive preoperative prediction method, shows a favorable predictive accuracy for MVI status in patients with HBV-related HCC.
View article: Morphology-adaptive total variation for the reconstruction of quantitative susceptibility map from the magnetic resonance imaging phase
Morphology-adaptive total variation for the reconstruction of quantitative susceptibility map from the magnetic resonance imaging phase Open
Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging technique that quantifies the magnetic susceptibility distribution within biological tissues. QSM calculates the underlying magnetic susceptibility by deconvolving t…
View article: Radiomic Signature of Computed Tomography Imaging for Prediction of Survival and Chemotherapeutic Benefits in Gastric Cancer
Radiomic Signature of Computed Tomography Imaging for Prediction of Survival and Chemotherapeutic Benefits in Gastric Cancer Open
View article: Progress in Magnetic Resonance Thoracic Ductography
Progress in Magnetic Resonance Thoracic Ductography Open
Intra The thoracic duct is the largest lymphatic vessel in the
body and is divided into many types based on its variable
morphology and anatomical position. However, it is hard to
be imaged because of its spindly structure and cov…
View article: Multifunctional superparamagnetic nanoparticles conjugated with fluorescein-labeled designed ankyrin repeat protein as an efficient HER2-targeted probe in breast cancer
Multifunctional superparamagnetic nanoparticles conjugated with fluorescein-labeled designed ankyrin repeat protein as an efficient HER2-targeted probe in breast cancer Open
Based on the discordance of human epidermal growth factor receptor-2 (HER2) expression between primary and metastatic/recurrent breast cancer, HER2 molecular imaging, which had potential to systemically assess and dynamically monitor HER2 …