Yilong Zhang
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View article: Assessing Effects of Riboflavin/ <scp>UV</scp> ‐A Cross‐Linking on Aqueous Outflow Facility, Corneal Biomechanics and Their Association With Intraocular Pressure
Assessing Effects of Riboflavin/ <span>UV</span> ‐A Cross‐Linking on Aqueous Outflow Facility, Corneal Biomechanics and Their Association With Intraocular Pressure Open
Riboflavin/UV‐A corneal collagen cross‐linking (CXL) is a standard treatment for early‐stage keratoconus. However, quantitative CXL outcomes remain limited. This study evaluated CXL effects on outflow facility and corneal biomechanics at i…
View article: Quantitative Characterization of Undulation Patterns and Regional Features of the Oral Basement Membrane Zone Using Optical Coherence Tomography
Quantitative Characterization of Undulation Patterns and Regional Features of the Oral Basement Membrane Zone Using Optical Coherence Tomography Open
Alterations in the undulation pattern of the basement membrane zone (BMZ) reflect early pathological changes in oral squamous cell carcinoma (OSCC). Optical coherence tomography (OCT) provides real‐time, high‐resolution, in vivo three‐dime…
View article: Cost-effectiveness of brexpiprazole for the treatment of major depressive disorder in Japan
Cost-effectiveness of brexpiprazole for the treatment of major depressive disorder in Japan Open
Brexpiprazole, especially when initiated early, was a cost-effective adjunctive treatment for patients with MDD and a history of inadequate response to SSRI/SNRI.
View article: Assessment of minimum clinically important difference in symptoms and functionality of Japanese patients with major depressive disorder following inadequate response to antidepressants: a post hoc analysis of the long-term study of brexpiprazole augmentation therapy in Japanese patients with major depressive disorder
Assessment of minimum clinically important difference in symptoms and functionality of Japanese patients with major depressive disorder following inadequate response to antidepressants: a post hoc analysis of the long-term study of brexpiprazole augmentation therapy in Japanese patients with major depressive disorder Open
Background and objectives The aim of this study was to apply the minimum clinically important difference (MCID) concept to clinical results for Japanese patients with major depressive disorder following inadequate response to antidepressan…
View article: Zinc Oxide Nanoparticle Loaded L-Carnosine Biofunctionalized Polyacrylonitrile Nanofibrous Wound Dressing for Post-Surgical Treatment of Melanoma
Zinc Oxide Nanoparticle Loaded L-Carnosine Biofunctionalized Polyacrylonitrile Nanofibrous Wound Dressing for Post-Surgical Treatment of Melanoma Open
Nanofibrous dressing materials with an antitumor function can potentially inhibit recurrence of melanoma following the surgical excision of skin tumors. In this study, hydrolyzed polyacrylonitrile (hPAN) nanofibers biofunctionalized with L…
View article: Characterizing Viscoelasticity of Corneal Stromal Models Using Non-Contact Air-Pulse Optical Coherence Elastography (OCE) and Validating Using Ramp–Hold Relaxation Testing
Characterizing Viscoelasticity of Corneal Stromal Models Using Non-Contact Air-Pulse Optical Coherence Elastography (OCE) and Validating Using Ramp–Hold Relaxation Testing Open
Corneal biomechanical properties are closely related to the cornea’s physiological and pathological conditions, primarily determined by the stromal layer. However, little is known about the influence of corneal cell interaction on the visc…
View article: Simulation study of competitive adsorption of CH4/CO2 and CH4/N2 in anthracite coal
Simulation study of competitive adsorption of CH4/CO2 and CH4/N2 in anthracite coal Open
View article: Cost-Effectiveness Study of Difamilast 1% for the Treatment of Atopic Dermatitis in Adult Japanese Patients
Cost-Effectiveness Study of Difamilast 1% for the Treatment of Atopic Dermatitis in Adult Japanese Patients Open
The results suggest that difamilast 1% is a more cost-effective treatment option compared with delgocitinib 0.5% in Japanese adult patients with moderate-to-severe AD and compared with placebo in adult patients with all-severity AD from a …
View article: VP-net: an end-to-end deep learning network for elastic wave velocity prediction in human skin in vivo using optical coherence elastography
VP-net: an end-to-end deep learning network for elastic wave velocity prediction in human skin in vivo using optical coherence elastography Open
Introduction Acne vulgaris, one of the most common skin conditions, affects up to 85% of late adolescents, currently no universally accepted assessment system. The biomechanical properties of skin provide valuable information for the asses…
View article: Performance Evaluation of Routing Algorithm in Satellite Self-Organizing Network on OMNeT++ Platform
Performance Evaluation of Routing Algorithm in Satellite Self-Organizing Network on OMNeT++ Platform Open
Self-organizing networks of small satellites have gradually gained attention in recent years. However, self-organizing networks of small satellites have high topological change frequency, large transmission delay, and complex communication…
View article: Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Difamilast 1% and Delgocitinib 0.5% in Patients with Moderate-to-Severe Atopic Dermatitis
Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Difamilast 1% and Delgocitinib 0.5% in Patients with Moderate-to-Severe Atopic Dermatitis Open
View article: Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography
Characterizing Biomechanics of Limbal Niche Using Vibrational Optical Coherence Elastography Open
The limbal niche is an adult source of epithelial stem cells which regenerate the cornea epithelium. The architecture and biomechanical properties of the limbus have previously been demonstrated to change due to aging and disease. This stu…
View article: Quantitative assessment of the oral microvasculature using optical coherence tomography angiography
Quantitative assessment of the oral microvasculature using optical coherence tomography angiography Open
Introduction Early diagnosis of oral squamous cell carcinoma can greatly improve treatment success rate and patient survival. Although Optical Coherence Tomography (OCT) based Angiography (OCTA) is a promising in vivo technique in oral ima…
View article: Quantitative Optimization of Handheld Probe External Pressure on Dermatological Microvasculature Using Optical Coherence Tomography-Based Angiography
Quantitative Optimization of Handheld Probe External Pressure on Dermatological Microvasculature Using Optical Coherence Tomography-Based Angiography Open
Optical Coherence Tomography (OCT)-based angiography (OCTA) is a high-resolution, high-speed, and non-invasive imaging method that can provide vascular mapping of subcutaneous tissue up to approximately 2 mm. In dermatology applications of…
View article: Robust Ultrafast Projection Pipeline for Structural and Angiography Imaging of Fourier-Domain Optical Coherence Tomography
Robust Ultrafast Projection Pipeline for Structural and Angiography Imaging of Fourier-Domain Optical Coherence Tomography Open
The current methods to generate projections for structural and angiography imaging of Fourier-Domain optical coherence tomography (FD-OCT) are significantly slow for prediagnosis improvement, prognosis, real-time surgery guidance, treatmen…
View article: Effects of Excitation Angle on Air-Puff-Stimulated Surface Acoustic Wave-Based Optical Coherence Elastography (SAW-OCE)
Effects of Excitation Angle on Air-Puff-Stimulated Surface Acoustic Wave-Based Optical Coherence Elastography (SAW-OCE) Open
Increased stiffness of tissues has been recognised as a diagnostic feature of pathologies. Tissue stiffness characterisation usually involves the detection of tissue response from mechanical stimulation. Air-puff optical coherence elastogr…
View article: Macro-meso damage characteristics of coal body under different pressure relief conditions
Macro-meso damage characteristics of coal body under different pressure relief conditions Open
View article: VET: Vasculature Extraction Transformer for Single-Scan Optical Coherence Tomography Angiography
VET: Vasculature Extraction Transformer for Single-Scan Optical Coherence Tomography Angiography Open
Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality for analyzing skin microvasculature, enabling non-invasive diagnosis and treatment monitoring. Traditional OCTA algorithms necessitate at least two-repeated…
View article: Brown Sequard syndrome in a patient with Klippel-Feil syndrome following minor trauma: a case report and literature review
Brown Sequard syndrome in a patient with Klippel-Feil syndrome following minor trauma: a case report and literature review Open
Background There are some cases of Klippel-Feil syndrome with spinal cord injury in clinical work. However, there is no literature report on Brown-Sequard syndrome after trauma. We report a case of Brown-Sequard syndrome following minor tr…
View article: Causal relationship between sarcopenia and osteoarthritis: a bi-directional two-sample mendelian randomized study
Causal relationship between sarcopenia and osteoarthritis: a bi-directional two-sample mendelian randomized study Open
Background Previous studies have shown that osteoarthritis (OA) and sarcopenia (SP) are closely related to each other, but the causal relationships between them have not been established. The aim of this study was to investigate the causal…
View article: Deep-Learning-based Vasculature Extraction for Single-Scan Optical Coherence Tomography Angiography
Deep-Learning-based Vasculature Extraction for Single-Scan Optical Coherence Tomography Angiography Open
Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that extends the functionality of OCT by extracting moving red blood cell signals from surrounding static biological tissues. OCTA has emerged as a valuable…
View article: Supplementary Figure 1 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer
Supplementary Figure 1 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer Open
Supplementary Figure 1. Goodness-of-Fit Plots for the Pharmacokinetic Model
View article: Data from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer
Data from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer Open
Purpose: Rilotumumab is an investigational, fully human monoclonal antibody to hepatocyte growth factor. In a randomized phase II study, trends toward improved survival were observed with rilotumumab (7.5 or 15 mg/kg) plus epirubici…
View article: Supplementary Figure 2 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer
Supplementary Figure 2 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer Open
Supplementary Figure 2. Goodness-of-Fit Plots for the Tumor Growth Model
View article: Supplementary Figure 1 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer
Supplementary Figure 1 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer Open
Supplementary Figure 1. Goodness-of-Fit Plots for the Pharmacokinetic Model
View article: Supplementary Figure 2 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer
Supplementary Figure 2 from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer Open
Supplementary Figure 2. Goodness-of-Fit Plots for the Tumor Growth Model
View article: Data from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer
Data from Rilotumumab Exposure–Response Relationship in Patients with Advanced or Metastatic Gastric Cancer Open
Purpose: Rilotumumab is an investigational, fully human monoclonal antibody to hepatocyte growth factor. In a randomized phase II study, trends toward improved survival were observed with rilotumumab (7.5 or 15 mg/kg) plus epirubici…
View article: Knockdown of lncRNA NKILA suppresses sevoflurane-induced neuronal cell injury partially by targeting miR-205-5p/ELAVL1 axis
Knockdown of lncRNA NKILA suppresses sevoflurane-induced neuronal cell injury partially by targeting miR-205-5p/ELAVL1 axis Open
Sevoflurane (Sev) is a wildly used volatile anesthetic agent that induces neurotoxicity. Long non-coding RNAs (lncRNAs) have been demonstrated to be involved in Sev-induced neuronal injury. Here, we investigated the role of NF-kappaB-inter…
View article: Additional file 1 of Causal relationship between sarcopenia and osteoarthritis: a bi-directional two-sample mendelian randomized study
Additional file 1 of Causal relationship between sarcopenia and osteoarthritis: a bi-directional two-sample mendelian randomized study Open
Additional file 1: Table S1. The selected SNPs in the analysis of GS-KOA; Table S2. The selected SNPs in the analysis of GS-HOA; Table S3. The selected SNPs in the analysis of GS-TKR; Table S4. The selected SNPs in the analysis of GS-THR; …
View article: Asymmetries and relationships between muscle strength, proprioception, biomechanics, and postural stability in patients with unilateral knee osteoarthritis
Asymmetries and relationships between muscle strength, proprioception, biomechanics, and postural stability in patients with unilateral knee osteoarthritis Open
Background: The pathological mechanism of knee osteoarthritis (KOA) is unknown. KOA degeneration may be associated with changes in muscle strength, proprioception, biomechanics, and postural stability. Objective: This study aimed to assess…