Yimei Jiang
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View article: Mendelian randomization analysis of free cholesterol in VLDL subfractions and the risk of colorectal cancer
Mendelian randomization analysis of free cholesterol in VLDL subfractions and the risk of colorectal cancer Open
View article: Multi-omics profiling of metastatic colorectal cancer reveals the transcriptional network of focal adhesion and immune suppression and the role of p-RPS6
Multi-omics profiling of metastatic colorectal cancer reveals the transcriptional network of focal adhesion and immune suppression and the role of p-RPS6 Open
We identified the key transcriptome network in mCRC and confirmed the important role for RPS6 phosphorylation in mCRC. Our study suggested that the features of mCRC tumors were not driven by gene mutations. We revealed the EMT feature and …
View article: Long-term outcomes of single-incision laparoscopic surgery for colorectal cancer, a single-center, open-label, randomized controlled trial
Long-term outcomes of single-incision laparoscopic surgery for colorectal cancer, a single-center, open-label, randomized controlled trial Open
Background: The efficacy of single-incision laparoscopic surgery (SILS) for colorectal cancer remains controversial due to uncertainties regarding long-term outcomes. This study aimed to compare the 5-year outcomes of SILS and conventional…
View article: Intervention for disease-based students improving perceived physical literacy in university required physical education： PBL model
Intervention for disease-based students improving perceived physical literacy in university required physical education： PBL model Open
体育素养的发展对个体的长期健康至关重要，其素质可以描述为一个人愿意运用运动的潜力来提升生活质量的动机和能力。高校体育课程是培养体育素养的关键，有必要帮助因疾病无法参与剧烈运动的学生参与体育活动，促进心理健康。本研究以体育素养基本策略为基础，运用PBL教学模式，对在必修体育课上学习疾病的大学生进行为期10周的课程干预。结果显示，干预组在10周后体育素养得分和体育学习兴趣得分显著高于遵循传统课程模式的对照组，虽然有所提高，但差异不具有统计学意义。本研究的课程干预方案不仅为高校体…
View article: Integrating the Memory Support Intervention into the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C): can improving memory for treatment in midlife and older adults improve patient outcomes? Study protocol for a randomized controlled trial
Integrating the Memory Support Intervention into the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C): can improving memory for treatment in midlife and older adults improve patient outcomes? Study protocol for a randomized controlled trial Open
View article: Editorial: Identification of potential therapeutic targets for the tumor microenvironment of gastrointestinal tumor
Editorial: Identification of potential therapeutic targets for the tumor microenvironment of gastrointestinal tumor Open
Editorial: Identification of potential therapeutic targets for the tumor microenvironment of gastrointestinal tumor
View article: Single-Incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer (SILCS): Long-Term Outcomes of an Open-Label, Non-Inferiority, Randomised Controlled Trial
Single-Incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer (SILCS): Long-Term Outcomes of an Open-Label, Non-Inferiority, Randomised Controlled Trial Open
View article: The genomic and immune landscapes of gastric cancer and their correlations with <scp>HER2</scp> amplification and <scp>PD‐L1</scp> expression
The genomic and immune landscapes of gastric cancer and their correlations with <span>HER2</span> amplification and <span>PD‐L1</span> expression Open
Background Anti‐PD1/PD‐L1 antibody plus human epidermal growth factor receptor 2 (HER2) antibody and chemotherapy have become the new first‐line therapy for HER2 overexpression‐positive advanced gastric cancers (GC), suggesting that HER2 a…
View article: Editorial: The role of angiogenesis and immune response in tumor microenvironment of solid tumor
Editorial: The role of angiogenesis and immune response in tumor microenvironment of solid tumor Open
EDITORIAL article Front. Immunol., 18 April 2023Sec. Cancer Immunity and Immunotherapy Volume 14 - 2023 | https://doi.org/10.3389/fimmu.2023.1195390
View article: Supplementary Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis
Supplementary Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis Open
Roles of PRPS1 and PRPS1 in cell cycle progression and some of experimental verifications are included in this file.
View article: Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis
Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis Open
Nucleotide supply is essential for DNA replication in proliferating cells, including cancer cells. Ribose-phosphate diphosphokinase 1 (PRPS1) is a key enzyme to produce the consensus precursor of nucleotide synthesis. PRPS1 participates in…
View article: Supplementary Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis
Supplementary Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis Open
Roles of PRPS1 and PRPS1 in cell cycle progression and some of experimental verifications are included in this file.
View article: Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis
Data from Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis Open
Nucleotide supply is essential for DNA replication in proliferating cells, including cancer cells. Ribose-phosphate diphosphokinase 1 (PRPS1) is a key enzyme to produce the consensus precursor of nucleotide synthesis. PRPS1 participates in…
View article: VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19
VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19 Open
Among adults with mild-to-moderate Covid-19 who were at risk for progression, VV116 was noninferior to nirmatrelvir-ritonavir with respect to the time to sustained clinical recovery, with fewer safety concerns. (Funded by Vigonvita Life Sc…
View article: Cancer stem cell-like cells-derived exosomal lncRNA CDKN2B-AS1 promotes biological characteristics in thyroid cancer via miR-122-5p/P4HA1 axis
Cancer stem cell-like cells-derived exosomal lncRNA CDKN2B-AS1 promotes biological characteristics in thyroid cancer via miR-122-5p/P4HA1 axis Open
View article: Oncologic outcomes of single-incision laparoscopic surgery versus conventional laparoscopic surgery for colorectal cancer (CSILS): study protocol for a multicentre, prospective, open-label, noninferiority, randomized controlled trial
Oncologic outcomes of single-incision laparoscopic surgery versus conventional laparoscopic surgery for colorectal cancer (CSILS): study protocol for a multicentre, prospective, open-label, noninferiority, randomized controlled trial Open
Background In most previous studies, single-incision laparoscopic surgery (SILS) for colorectal cancer (CRC) was feasible and safe in the short term. However, long-term oncologic outcomes remain uncertain, as only a few studies contained l…
View article: AFF4 Predicts the Prognosis of Colorectal Cancer Patients and Suppresses Colorectal Cancer Metastasis via Promoting CDH1 Expression
AFF4 Predicts the Prognosis of Colorectal Cancer Patients and Suppresses Colorectal Cancer Metastasis via Promoting CDH1 Expression Open
Introduction AF4/FMR2 family member 4 (AFF4) is a core component of super elongation complex (SEC) and regulates the transcription elongation of many genes. AFF4 depletion or amplification is associated with multiple cancers, but its role …
View article: Comparative Effectiveness of Enhanced Recovery After Surgery Program Combined With Single-Incision Laparoscopic Surgery in Colorectal Cancer Surgery: A Retrospective Analysis
Comparative Effectiveness of Enhanced Recovery After Surgery Program Combined With Single-Incision Laparoscopic Surgery in Colorectal Cancer Surgery: A Retrospective Analysis Open
Background Recently, enhanced recovery after surgery (ERAS) has been widely used in the perioperative management of colorectal cancer (CRC). This study aimed to evaluate the safety and feasibility of ERAS combined with single-incision lapa…
View article: Short-Term Outcomes of Single-Incision Laparoscopic Surgery for Colorectal Cancer: A Single-Center, Open-Label, Non-Inferiority, Randomized Clinical Trial
Short-Term Outcomes of Single-Incision Laparoscopic Surgery for Colorectal Cancer: A Single-Center, Open-Label, Non-Inferiority, Randomized Clinical Trial Open
Objective To date, well-designed randomized controlled trials examining the safety, efficacy, and long-term outcomes of single-incision laparoscopic surgery (SILS) for colorectal cancer are scarce. The aim of the current study was to compa…
View article: Pure transvaginal natural orifice transluminal endoscopic surgery right hemicolectomy for colon cancer: A case report
Pure transvaginal natural orifice transluminal endoscopic surgery right hemicolectomy for colon cancer: A case report Open
vNOTES right hemicolectomy, performed by well-experienced surgeons, overcomes the technical challenges of pure NOTES and may be feasible for colon cancer.
View article: Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods
Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods Open
View article: Exosomal miR-200c-3p negatively regulates the migration and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC)
Exosomal miR-200c-3p negatively regulates the migration and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC) Open
View article: Additional file 1 of Exosomal miR-200c-3p negatively regulates the migraion and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC)
Additional file 1 of Exosomal miR-200c-3p negatively regulates the migraion and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC) Open
Additional file 1: Table S1. Full list of differentially expressed exosomal miRNAs after LPS stimulation in HCT-116 cells.
View article: Additional file 1 of Exosomal miR-200c-3p negatively regulates the migration and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC)
Additional file 1 of Exosomal miR-200c-3p negatively regulates the migration and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC) Open
Additional file 1: Table S1. Full list of differentially expressed exosomal miRNAs after LPS stimulation in HCT-116 cells.
View article: Additional file 1 of Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods
Additional file 1 of Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods Open
Additional file 1.
View article: Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis
Cell-Cycle–Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis Open
Nucleotide supply is essential for DNA replication in proliferating cells, including cancer cells. Ribose-phosphate diphosphokinase 1 (PRPS1) is a key enzyme to produce the consensus precursor of nucleotide synthesis. PRPS1 participates in…
View article: ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet‐derived growth factor BB
ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet‐derived growth factor BB Open
ETS transcription factors play important roles in tumor cell invasion, differentiation and angiogenesis. In this study, we initially demonstrated that ETS translocation variant 5 (ETV5) is abnormally upregulated in colorectal cancer (CRC),…
View article: Art Design Specialty Teaching Reform based on the Practice Skills Contest Platform
Art Design Specialty Teaching Reform based on the Practice Skills Contest Platform Open
Art design practice skills competition is important carrier of cultivating the ability of practical application to encourage, promote and practice for students majoring in art design class.Based on the platform of the testing standard, in …
View article: Impact of adherence to GOLD guidelines on 6-minute walk distance, MRC dyspnea scale score, lung function decline, quality of life, and quality-adjusted life years in a Shanghai suburb
Impact of adherence to GOLD guidelines on 6-minute walk distance, MRC dyspnea scale score, lung function decline, quality of life, and quality-adjusted life years in a Shanghai suburb Open
We performed a 1-year cluster-randomized field trial to assess the effect of standardized management of chronic obstructive pulmonary disease (COPD) on lung function and quality of life (QOL) measures in patients in China. We used the Glob…