Explanipedia

Forty years of fertility transition in Hong Kong Open

Yawen Bai, Paul Yip, B Li, Kam Pui Wat, Eddy Lam , et al. · 2025

WP-MOD: A multi-omics and taxonomy database for woody plants Open

Qi Wang, Shaoxuan Luo, Yixiang Yang, Yawen Bai, Jun-Rong Wei , et al. · 2025

Woody plants, including trees, shrubs, and woody vines, are vital components of terrestrial ecosystems and are critical for maintaining biodiversity, regulating climate, and supporting human livelihoods. Over the past decade, the accumulat…

ANAgdb: a multi-omics and taxonomy database for ANA-grade Open

Zhonglong Guo, Shaoxuan Luo, Qi Wang, Yixiang Yang, Yawen Bai , et al. · 2024

By integrating the comprehensive resources and tools, ANAgdb aims to significantly advance research in phylogenomics and taxonomic studies, providing a robust platform for researchers to explore the genetic and morphological diversities of…

Structural basis for linker histone H5–nucleosome binding and chromatin fiber compaction Open

Wenyan Li, Jie Hu, Feng Song, Juan Yu, Xin Peng , et al. · 2024

Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4 Open

Bing‐Rui Zhou, Hanqiao Feng, Furong Huang, Iris Zhu, Stephanie Portillo‐Ledesma , et al. · 2024

The Complete Mitogenomes of Two Species of Snakehead Fish (Perciformes: Channidae): Genome Characterization and Phylogenetic Analysis Open

Tangjun Xu, Wenwen Zhang, Yao Li, Jiachen Wang, Yawen Bai , et al. · 2024

Channidae (snakehead fish) is a family of medium-to-large freshwater carnivorous fish and contain the genus, Channa. Here, the complete mitogenomes of two Channa fish were determined and comparatively analyzed with the mitogenomes of 16 ot…

The cysteine-rich domain in CENP-A chaperone Scm3HJURP ensures centromere targeting and kinetochore integrity Open

H. Diego Folco, Hua Xiao, David Wheeler, Hanqiao Feng, Yawen Bai , et al. · 2023

Centromeric chromatin plays a crucial role in kinetochore assembly and chromosome segregation. Centromeres are specified through the loading of the histone H3 variant CENP-A by the conserved chaperone Scm3/HJURP. The N-terminus of Scm3/HJU…

The human LIN28B nucleosome is inherently pre-positioned for efficient binding of multiple OCT4s without H3 K27 acetylation Open

Tengfei Lian, R. Guan, Bing‐Rui Zhou, Yawen Bai · 2023

Pioneer transcription factors possess the unique ability to access DNA within tightly packed chromatin structures, playing pivotal roles in cell differentiation and reprogramming. However, their precise mechanism for recognizing nucleosome…

Structural mechanism of synergistic targeting of the<i>CX3CR1</i>nucleosome by PU.1 and C/EBP⍺ Open

Tengfei Lian, R. Guan, Bing‐Rui Zhou, Yawen Bai · 2023

Pioneer transcription factors are vital for cell fate changes. PU.1 and C/EBP⍺ work together to regulate hematopoietic stem cell differentiation. However, how they recognize in vivo nucleosomal DNA targets remain elusive. Here we report th…

Structural mechanism of LIN28B nucleosome targeting by OCT4 Open

R. Guan, Tengfei Lian, Bing‐Rui Zhou, David Wheeler, Yawen Bai · 2023

MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain Open

Dustin C. Becht, Brianna J. Klein, Akinori Kanai, Suk Min Jang, Khan L. Cox , et al. · 2023

16-Channel Wavelength Division Multiplexers Based on Subwavelength Grating Open

Yawen Bai, Lin Wang, Lei Zhang, Pengfei Wang, Bo Peng · 2023

Wavelength Division Multiplexing (WDM) plays an important role in optical interconnection. In this paper, a 16-channel WDM device is designed on a Silicon-On-Insulator (SOI) substrate by using a sub-wavelength grating (SWG) structure, whic…

Structural mechanism of<i>LIN28B</i>nucleosome targeting by OCT4 for pluripotency Open

R. Guan, Tengfei Lian, Bing‐Rui Zhou, Yawen Bai · 2023

SUMMARY Pioneer transcription factors are essential for cell fate changes by targeting closed chromatin. OCT4 is a crucial pioneer factor that can induce cell reprogramming. However, the structural basis of how pioneer factors recognize th…

Structural Mechanism of TAF-Iβ Chaperone Function on Linker Histone H1.10 Open

Haniqao Feng, Bing‐Rui Zhou, Charles D. Schwieters, Yawen Bai · 2022

Identification and validation of glomerulotubular crosstalk genes mediating IgA nephropathy by integrated bioinformatics Open

Yawen Bai, Yajing Li, Yali Xi, Chunjie Ma · 2022

Structural Mechanism of Taf-I B Chaperone Function on Linker Histone H1.10 Open

Hanqiao Feng, Bing‐Rui Zhou, Charles D. Schwieters, Yawen Bai · 2022

Additional file 1 of Identification and validation of glomerulotubular crosstalk genes mediating IgA nephropathy by integrated bioinformatics Open

Yawen Bai, Yajing Li, Yali Xi, Chunjie Ma · 2022

Additional file 1.

Identification and Validation of Glomerulotubular Crosstalk Genes Mediating IgA Nephropathy by Integrated Bioinformatics Open

Yawen Bai, Yajing Li, Yali Xi, Chunjie Ma · 2021

BackgroundIgA nephropathy (IgAN), which has been reported as the most prevalent glomerulonephritis globally, is the major contributor to end-stage renal illness. This bioinformatics study aimed to explore glomeruli-tubulointerstitial cross…

Preparation of scFv stabilized chromatosomes for single-particle cryo-EM structure determination Open

Bing‐Rui Zhou, Yawen Bai · 2021

Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation Open

R. Guan, Tengfei Lian, Bing‐Rui Zhou, Emily M. He, Carl Wu , et al. · 2021

Editorial Board Open

Lila M. Gierasch, F. Peter Guengerich, Alex Toker, C.J. Goodman, Ruma Banerjee , et al. · 2020

Editorial Board Open

Lila M. Gierasch, F. Peter Guengerich, Alex Toker, C.J. Goodman, Ruma Banerjee , et al. · 2020

Editorial Board Open