Yimou Lin
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View article: Immune-related adverse events are a potent predictor of post-transplant rejection in HCC: a multicentre retrospective cohort study
Immune-related adverse events are a potent predictor of post-transplant rejection in HCC: a multicentre retrospective cohort study Open
Background Immune checkpoint inhibitors (ICIs) enable successful hepatocellular carcinoma (HCC) downstaging or bridging for liver transplantation (LT) but increase allograft rejection risk. Although immune-related adverse events (irAEs) re…
View article: Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort study
Development and validation of a novel prognostic model to predict 1-year post-transplant mortality for acute-on-chronic hepatitis B liver failure: a nationwide, multicentre, cohort study Open
View article: Development and Validation of A Novel Prognostic Model to Predict 1-Year Post-Transplant Mortality for Acute-on-Chronic Hepatitis B Liver Failure: A Nationwide, Multicenter, Cohort Study
Development and Validation of A Novel Prognostic Model to Predict 1-Year Post-Transplant Mortality for Acute-on-Chronic Hepatitis B Liver Failure: A Nationwide, Multicenter, Cohort Study Open
View article: An integrated proteomics and metabolomics approach to assess graft quality and predict early allograft dysfunction after liver transplantation: a retrospective cohort study
An integrated proteomics and metabolomics approach to assess graft quality and predict early allograft dysfunction after liver transplantation: a retrospective cohort study Open
Background: Early allograft dysfunction (EAD) is a common complication after liver transplantation (LT) and is associated with poor prognosis. Graft itself plays a major role in the development of EAD. We aimed to reveal the EAD-specific m…
View article: Development and validation of a nomogram model for predicting chronic kidney disease after liver transplantation: a multi-center retrospective study
Development and validation of a nomogram model for predicting chronic kidney disease after liver transplantation: a multi-center retrospective study Open
View article: Serum Exosome-Derived piRNAs Could Be Promising Biomarkers for HCC Diagnosis
Serum Exosome-Derived piRNAs Could Be Promising Biomarkers for HCC Diagnosis Open
piRNAs enriched the components of serum exosomes from HCC and could serve as promising biomarkers for HCC diagnosis.
View article: Immunotherapy for hepatocellular carcinoma recurrence after liver transplantation, can we harness the power of immune checkpoint inhibitors?
Immunotherapy for hepatocellular carcinoma recurrence after liver transplantation, can we harness the power of immune checkpoint inhibitors? Open
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death globally and liver transplantation (LT) can serve as the best curative treatment option. However, HCC recurrence after LT remains the major obstacle to the…
View article: Assessing Donor Liver Quality and Restoring Graft Function in the Era of Extended Criteria Donors
Assessing Donor Liver Quality and Restoring Graft Function in the Era of Extended Criteria Donors Open
Liver transplantation (LT) is the final treatment option for patients with end-stage liver disease. The increasing donor shortage results in the wide usage of grafts from extended criteria donors across the world. Using such grafts is asso…
View article: Primary nonfunction following liver transplantation: Learning of graft metabolites and building a predictive model
Primary nonfunction following liver transplantation: Learning of graft metabolites and building a predictive model Open
Dear Editor, Primary nonfunction (PNF) is defined as the need for emergent re-transplant when a graft never presented any evidence of initial function following liver transplantation (LT) after excluding other causes such as acute cellular…
View article: Decoding the single-cell landscape and intercellular crosstalk in the transplanted liver: a 4-dimension mouse model
Decoding the single-cell landscape and intercellular crosstalk in the transplanted liver: a 4-dimension mouse model Open
Graft remodeling after transplantation maintains graft functionality and determines graft survival. However, a comprehensive understanding of cellular diversity and interplay during graft remodeling remains to be fully characterized. In th…
View article: Nomogram to predict primary non-response to infliximab in patients with Crohn’s disease: a multicenter study
Nomogram to predict primary non-response to infliximab in patients with Crohn’s disease: a multicenter study Open
Background Infliximab (IFX) is effective at inducing and maintaining clinical remission and mucosal healing in patients with Crohn’s disease (CD); however, 9%–40% of patients do not respond to primary IFX treatment. This study aimed to con…