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View article: Differences in milk microbiota between healthy cows and those with recurring Klebsiella mastitis
Differences in milk microbiota between healthy cows and those with recurring Klebsiella mastitis Open
Klebsiella spp. infections are an important cause of severe clinical mastitis and recurrent infections, resulting in a poor response to antimicrobial agents and causing substantial economic impacts on the dairy industry. Therefore, investi…
View article: Bovine milk-derived extracellular vesicles reduce oxidative stress and ferroptosis induced by Klebsiella pneumoniae in bovine mammary epithelial cells
Bovine milk-derived extracellular vesicles reduce oxidative stress and ferroptosis induced by Klebsiella pneumoniae in bovine mammary epithelial cells Open
Background Ferroptosis is characterized by increased production of reactive oxygen species (ROS) and membrane lipid peroxidation that can exacerbate inflammatory damage. Extracellular vesicles (EVs) isolated from bovine milk have many biol…
View article: Colostrum-derived extracellular vesicles: potential multifunctional nanomedicine for alleviating mastitis
Colostrum-derived extracellular vesicles: potential multifunctional nanomedicine for alleviating mastitis Open
Bovine mastitis is an infectious disease that causes substantial economic losses to the dairy industry worldwide. Current antibiotic therapy faces issues of antibiotic misuse and antimicrobial resistance, which has aroused concerns for bot…
View article: Antimicrobial Resistance and Use on Chinese Dairy Farms: Awareness and Opinions Regarding Selective Treatments of Farm Managers
Antimicrobial Resistance and Use on Chinese Dairy Farms: Awareness and Opinions Regarding Selective Treatments of Farm Managers Open
Background: In China’s expanding dairy industry, a lack of oversight regarding antimicrobial use and increasing antimicrobial resistance are evident. Selective treatments of dairy cows for clinical mastitis or dry cow therapy are proposed …
View article: Differences in milk microbiota between healthy cows and cows with recurring<i>Klebsiella</i>mastitis
Differences in milk microbiota between healthy cows and cows with recurring<i>Klebsiella</i>mastitis Open
Klebsiella spp. infections continue to have a significant economic impact on the dairy industry, being an important cause of severe clinical mastitis, recurrent infections, and demonstrating poor response to antimicrobials. It is, therefor…
View article: Emerging role of extracellular vesicles in veterinary practice: novel opportunities and potential challenges
Emerging role of extracellular vesicles in veterinary practice: novel opportunities and potential challenges Open
Extracellular vesicles are nanoscale vesicles that transport signals between cells, mediating both physiological and pathological processes. EVs facilitate conserved intercellular communication. By transferring bioactive molecules between …
View article: Comparative genomic analyses of Klebsiella pneumoniae K57 capsule serotypes isolated from bovine mastitis in China
Comparative genomic analyses of Klebsiella pneumoniae K57 capsule serotypes isolated from bovine mastitis in China Open
Klebsiella pneumoniae can cause severe clinical mastitis in dairy cows, with K. pneumoniae type K57 (K57-KP) being the most common capsular serotype. To identify virulence factors and antimicrobial-resistance (AMR) genes of K57-KP with var…