Yao Xue
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View article: Policy-Driven Investments in a Downturn: The Role and Potential of ARH REITs in China's Housing Market Transition
Policy-Driven Investments in a Downturn: The Role and Potential of ARH REITs in China's Housing Market Transition Open
As China's real estate sector contends with a significant downturn, Affordable Rental Housing (ARH) REITs are gaining prominence as a pivotal financial innovation. These instruments are designed to channel private capital into addressing t…
View article: Hyaluronan catabolism supports the peritoneal disseminated metastasis of cancer through the glucuronic acid pathway
Hyaluronan catabolism supports the peritoneal disseminated metastasis of cancer through the glucuronic acid pathway Open
When disseminated into the peritoneal cavity at the very early stage, cancer cells must adapt to the glucose- and oxygen-limited environment in peritoneal fluid. To investigate the molecular mechanisms enabling this adaptation, we conducte…
View article: 1274 IL-18BP inhibition elicits adaptive checkpoint expression and enables novel immune-checkpoint inhibitor (ICI) combinations in colon cancer
1274 IL-18BP inhibition elicits adaptive checkpoint expression and enables novel immune-checkpoint inhibitor (ICI) combinations in colon cancer Open
View article: Breast cancer cell-derived adrenomedullin confers cancer-associated adipose remodeling through the cAMP/Creb1/Zeb1 axis
Breast cancer cell-derived adrenomedullin confers cancer-associated adipose remodeling through the cAMP/Creb1/Zeb1 axis Open
View article: Rapidly progressing after umbilical cord blood transplantation in a boy with acute myeloid leukemia with KAT6A::EP300 fusion transcript
Rapidly progressing after umbilical cord blood transplantation in a boy with acute myeloid leukemia with KAT6A::EP300 fusion transcript Open
View article: Persistent global inequality in eye injury burden: a secondary analysis of the 2021 global burden of disease study (1990–2021)
Persistent global inequality in eye injury burden: a secondary analysis of the 2021 global burden of disease study (1990–2021) Open
Objectives Eye injury poses a significant challenge to the global burden of blindness. Using the Global Burden of Disease (GBD) database, this study aims to comprehensively assess the latest global burden of eye injury and examine its rela…
View article: Parotid Lymph Node Metastasis Prediction of Nasopharyngeal Carcinoma Based on Ultrasound Radiomics Analysis
Parotid Lymph Node Metastasis Prediction of Nasopharyngeal Carcinoma Based on Ultrasound Radiomics Analysis Open
The combined model using ultrasound radiomics has clinical utility in identifying useful US features and enhancing the diagnostic accuracy of ultrasound for detecting PLNM in patients with NPC.
View article: Oxidative stress-induced ZEB1 acetylation drives a hybrid epithelial-mesenchymal phenotype and promotes lung metastasis in triple-negative breast cancer
Oxidative stress-induced ZEB1 acetylation drives a hybrid epithelial-mesenchymal phenotype and promotes lung metastasis in triple-negative breast cancer Open
View article: Durable Molecular Remission in TCF3::HLF-Positive Pediatric B-ALL Using Post-Transplant Azacitidine, DLI and Blinatumomab
Durable Molecular Remission in TCF3::HLF-Positive Pediatric B-ALL Using Post-Transplant Azacitidine, DLI and Blinatumomab Open
Background: TCF3::HLF-positive B-cell acute lymphoblastic leukemia (B-ALL) is a rare, aggressive pediatric cancer characterized by chemotherapy resistance and high relapse rates following hematopoietic stem cell transplantation (HSCT), lea…
View article: SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma
SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma Open
BACKGROUND Metabolic dysregulation is considered a significant hallmark of hepatocellular carcinoma (HCC). SAC3 domain containing 1 (SAC3D1) functions in the cell cycle, and its expression is upregulated in various cancers. It is known tha…
View article: Self-consistency and congruence, perceived social support, and psychological resilience as predictors of professional identity of male nursing students among consecutive secondary and higher vocational education
Self-consistency and congruence, perceived social support, and psychological resilience as predictors of professional identity of male nursing students among consecutive secondary and higher vocational education Open
Objective Considering the traditional female nature of the nursing field, male nursing students often experience a strong urge to leave the profession. A robust professional identity (PI) is crucial for male nurses, as it can alleviate pro…
View article: Shared chromatin remodeling mutations drive concurrent rhabdomyosarcoma and leukemia in a pediatric patient
Shared chromatin remodeling mutations drive concurrent rhabdomyosarcoma and leukemia in a pediatric patient Open
The co-occurrence of rhabdomyosarcoma (RMS) and B-cell acute lymphoblastic leukemia (B-ALL) has been rarely reported, and the shared molecular drivers remain unidentified. This case report describes a pediatric patient diagnosed with both …
View article: The analysis of 5-ALA-PDT-induced cell death in ovarian cancer cells
The analysis of 5-ALA-PDT-induced cell death in ovarian cancer cells Open
View article: Pediatric Mixed Phenotype Acute Leukemia With <i>ETV6</i>::<i>ARNT</i> Fusion Gene Successfully Treated by Allogeneic Hematopoietic Stem Cell Transplantation
Pediatric Mixed Phenotype Acute Leukemia With <i>ETV6</i>::<i>ARNT</i> Fusion Gene Successfully Treated by Allogeneic Hematopoietic Stem Cell Transplantation Open
View article: Multiplexing and massive parallel sequencing of targeted DNA methylation to predict chronological age
Multiplexing and massive parallel sequencing of targeted DNA methylation to predict chronological age Open
Estimation of chronological age is particularly informative in forensic contexts. Assessment of DNA methylation status allows for the prediction of age, though the accuracy may vary across models. In this study, we started with a carefully…
View article: Global, regional, and national burden of children and adolescents with acute lymphoblastic leukemia from 1990 to 2021: a systematic analysis for the global burden of disease study 2021
Global, regional, and national burden of children and adolescents with acute lymphoblastic leukemia from 1990 to 2021: a systematic analysis for the global burden of disease study 2021 Open
Background Acute lymphoblastic leukemia (ALL) is a common cancer in children and adolescents, severely affecting their survival and health. With the discovery of new drugs and improved treatment options, the survival rate of ALL in childre…
View article: A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults
A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults Open
Objective This study aims to investigate the potential association between serum 25(OH)D levels and the risk of hyperlipidemia in adults through a prospective cohort study conducted in Zhejiang Province. Methods Baseline surveys and follow…
View article: <scp>CD312</scp> Promotes Paediatric Acute Lymphoblastic Leukaemia Through <scp>GNA15</scp>‐Mediated Non‐Classical <scp>GPCR</scp> Signalling Pathway
<span>CD312</span> Promotes Paediatric Acute Lymphoblastic Leukaemia Through <span>GNA15</span>‐Mediated Non‐Classical <span>GPCR</span> Signalling Pathway Open
The bone marrow‐infiltrated immune microenvironment plays a crucial role in blood system diseases, such as leukaemia. In this study, we aimed to investigate the critical role of the immune microenvironment in the onset and progression of c…
View article: PYCR1 promotes liver cancer cell growth and metastasis by regulating IRS1 expression through lactylation modification
PYCR1 promotes liver cancer cell growth and metastasis by regulating IRS1 expression through lactylation modification Open
Background Liver cancer (LC) is among the deadliest cancers worldwide, with existing treatments showing limited efficacy. This study aimed to elucidate the role and underlying mechanisms of pyrroline‐5‐carboxylate reductase 1 (PYCR1) as a …
View article: Graphical Abstract: Angew. Chem. Int. Ed. 21/2024
Graphical Abstract: Angew. Chem. Int. Ed. 21/2024 Open
Metal-Organic FrameworksIn their Research Article (e202319177), Lei Li, Qiang Xu et al. report a metal-organic framework-derived Zr/Ti bimetallic oxide solid solution anchored with Au nanoparticles through crystal engineering and derivatio…
View article: Gross motor skills and development of emotional understanding of children aged 3–6 years: Executive function as a mediator
Gross motor skills and development of emotional understanding of children aged 3–6 years: Executive function as a mediator Open
We investigated the relationship between the object control and emotional understanding of children aged 3 to 6 years, and the underlying mechanisms of its action. Using cluster sampling, we assessed the object control, inhibitory control,…
View article: Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China
Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China Open
The outcomes of children with acute lymphoblastic leukemia (ALL) have been incrementally improved with risk-directed chemotherapy but therapy responses remain heterogeneous. Parameters with added prognostic values are warranted to refine t…
View article: Prognostic model based on telomere-related genes predicts the risk of oral squamous cell carcinoma
Prognostic model based on telomere-related genes predicts the risk of oral squamous cell carcinoma Open
View article: Aligning the Cord Blood–Bone Marrow Differences and the Post-transplantation Clinical Manifestations by Single-Cell RNA-Seq
Aligning the Cord Blood–Bone Marrow Differences and the Post-transplantation Clinical Manifestations by Single-Cell RNA-Seq Open
Cord blood (CB) transplantation is a promising treatment for hematologic malignancies due to its strong graft-versus-leukemia effect and a low incidence of graft-versus-host disease. However, the risk of infection caused by delayed engraft…
View article: Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia
Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia Open
Acute lymphoblastic leukemia (ALL) is the most common malignant hematological diseases in children. An immunosuppressive microenvironment, particularly regulatory T cell (Treg) infiltration, has been documented to be highly associated with…
View article: [The efficacy and safety of CLAG-M/I regimen for relapsed or refractory acute myeloid leukemia in children].
[The efficacy and safety of CLAG-M/I regimen for relapsed or refractory acute myeloid leukemia in children]. Open
View article: A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer
A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer Open
View article: Mechanism of circADD2 as ceRNA in Childhood Acute Lymphoblastic Leukemia
Mechanism of circADD2 as ceRNA in Childhood Acute Lymphoblastic Leukemia Open
Background: Acute lymphocytic leukemia (ALL) is the most common malignant tumor in children. Increasing evidence suggests that circular RNAs (circRNAs) play critical regulatory roles in tumor biology. However, the expression patterns and r…
View article: Clinical characteristics of tumor lysis syndrome in childhood acute lymphoblastic leukemia
Clinical characteristics of tumor lysis syndrome in childhood acute lymphoblastic leukemia Open
View article: A Four-Immune Gene Prognostic Risk Model for Colorectal Adenocarcinoma Based on the TCGA&nbsp;and Immport Data Sets
A Four-Immune Gene Prognostic Risk Model for Colorectal Adenocarcinoma Based on the TCGA and Immport Data Sets Open
BackgroundAs one of the hot spots in oncology field, immune research provides new ideas for the diagnosis and treatment of tumors. Different histological types of colorectal cancer are different. Adenocarcinoma, as the type with the highes…