Yingjiang Xu
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View article: Cold-induced hepatocyte-derived exosomes activate brown adipose thermogenesis via miR-293-5p-mediated transcriptional reprogramming
Cold-induced hepatocyte-derived exosomes activate brown adipose thermogenesis via miR-293-5p-mediated transcriptional reprogramming Open
View article: Spontaneous renal artery dissection leading to multiple organ dysfunction syndrome and eventual death: A case report
Spontaneous renal artery dissection leading to multiple organ dysfunction syndrome and eventual death: A case report Open
Rationale: Spontaneous renal artery dissection (SRAD) is a rare vascular emergency with high mortality. Early diagnosis remains challenging due to nonspecific clinical manifestations. This case highlights diagnostic and therapeutic dilemma…
View article: New perspectives on polycystic ovary syndrome: hypothalamic-sympathetic-adipose tissue interaction
New perspectives on polycystic ovary syndrome: hypothalamic-sympathetic-adipose tissue interaction Open
View article: Correction: Lin et al. Huafengdan Inhibits Glioblastoma Cell Growth and Mobility by Acting on PLAU and CAV1 Targets. Pharmaceuticals 2025, 18, 428
Correction: Lin et al. Huafengdan Inhibits Glioblastoma Cell Growth and Mobility by Acting on PLAU and CAV1 Targets. Pharmaceuticals 2025, 18, 428 Open
In the original publication [...]
View article: Multi-omics analysis and experiments uncover the link between cancer intrinsic drivers, stemness, and immunotherapy in ovarian cancer with validation in a pan-cancer census
Multi-omics analysis and experiments uncover the link between cancer intrinsic drivers, stemness, and immunotherapy in ovarian cancer with validation in a pan-cancer census Open
Background Although immune checkpoint inhibitors (ICIs) represent a substantial breakthrough in cancer treatment, it is crucial to acknowledge that their efficacy is limited to a subset of patients. The heterogeneity and stemness of cancer…
View article: Metabolic disorders in polycystic ovary syndrome: from gut microbiota biodiversity to clinical intervention
Metabolic disorders in polycystic ovary syndrome: from gut microbiota biodiversity to clinical intervention Open
Polycystic ovary syndrome (PCOS) is a prevalent gynecologic endocrine disorder characterized by menstrual irregularities, elevated androgen levels, and ovulatory dysfunction. Its etiology is multifactorial. Emerging evidence indicates that…
View article: Cold-Induced Hepatocyte-Derived Exosomes Activate Brown Adipose Thermogenesis via miR-293-5p-Mediated Transcriptional Reprogramming
Cold-Induced Hepatocyte-Derived Exosomes Activate Brown Adipose Thermogenesis via miR-293-5p-Mediated Transcriptional Reprogramming Open
The liver-adipose axis serves as a fundamental regulatory network governing systemic lipid homeostasis, with hepatic-derived signals orchestrating adipose tissue plasticity through multimodal mechanisms. Comprehensive elucidation of these …
View article: Huafengdan Inhibits Glioblastoma Cell Growth and Mobility by Acting on PLAU and CAV1 Targets
Huafengdan Inhibits Glioblastoma Cell Growth and Mobility by Acting on PLAU and CAV1 Targets Open
Background: Glioblastoma (GBM) is considered a clinically refractory malignant tumor due to its high recurrence and malignancy, invasiveness, and poor prognosis. The ethnomedicine Huafengdan (HFD) is prepared using several Chinese herbs by…
View article: Coronary heart disease with pulmonary embolism: A case report
Coronary heart disease with pulmonary embolism: A case report Open
BACKGROUND Coronary heart disease (CHD) and pulmonary embolism (PE) are thrombotic diseases. Patients with CHD and PE are common in clinical practice. However, the clinical diagnosis of PE is challenging due to overlapping primary symptoms…
View article: Multi-omics analysis and experiments uncover the function of cancer stemness in ovarian cancer and establish a machine learning-based model for predicting immunotherapy responses
Multi-omics analysis and experiments uncover the function of cancer stemness in ovarian cancer and establish a machine learning-based model for predicting immunotherapy responses Open
Background The heterogeneity of cancer makes it challenging to predict its response to immunotherapy, highlighting the need to find reliable biomarkers for assessment. The sophisticated role of cancer stemness in mediating resistance to im…
View article: Multi-omics decipher the immune microenvironment and unveil therapeutic strategies for postoperative ovarian cancer patients
Multi-omics decipher the immune microenvironment and unveil therapeutic strategies for postoperative ovarian cancer patients Open
This study provides a novel PCD model and nomogram that can effectively predict the clinical prognosis and drug sensitivity of OC patients post-surgery.
View article: Integrated analysis and experiments uncover the function of disulfidptosis in predicting immunotherapy effectiveness and delineating immune landscapes in uterine corpus endometrial carcinoma
Integrated analysis and experiments uncover the function of disulfidptosis in predicting immunotherapy effectiveness and delineating immune landscapes in uterine corpus endometrial carcinoma Open
Introduction Recently, a novel type of metabolic-regulated cell demise titled disulfidptosis has been discovered. Studies have demonstrated its importance in immune responses against cancer and its impact on the proliferation of cancer cel…
View article: Semaglutide Alleviates Ovary Inflammation via the AMPK/SIRT1/NF‑κB Signaling Pathway in Polycystic Ovary Syndrome Mice
Semaglutide Alleviates Ovary Inflammation via the AMPK/SIRT1/NF‑κB Signaling Pathway in Polycystic Ovary Syndrome Mice Open
Semaglutide alleviates ovarian inflammation via the AMPK/SIRT1/NF‑κB signaling pathway in PCOS mice.
View article: Coronary heart disease with pulmonary embolism: a case report
Coronary heart disease with pulmonary embolism: a case report Open
Background: Coronary heart disease and pulmonary embolism are both thrombotic diseases, and now, patients with coronary heart disease and pulmonary embolism are not uncommon in clinical practice. However, there are some challenges in clini…
View article: A new step-wise surgical technique of knapsack-like uterine compression sutures for intractable postpartum hemorrhage in cesarean section
A new step-wise surgical technique of knapsack-like uterine compression sutures for intractable postpartum hemorrhage in cesarean section Open
Background Intractable postpartum hemorrhage (PPH) during cesarean section has been a significant concern for obstetricians. We aimed to explore the effectiveness and safety of a new type of uterine compression suture, the step-wise surgic…
View article: Glycosylation-Related Genes predict prognosis in Hepatocellular carcinoma
Glycosylation-Related Genes predict prognosis in Hepatocellular carcinoma Open
(1) Background： Hepatocellular carcinoma (HCC) remains a significant challenge in the field of oncology despite improvements in diagnosis and treatment with surgical resection, liver transplantation, and various local therapies. Advanced H…
View article: Preliminary application of three-dimensional venography and fusion navigation technique in May-Thurner syndrome
Preliminary application of three-dimensional venography and fusion navigation technique in May-Thurner syndrome Open
3D venography and its fusion navigation technique can improve prediction of the coverage area of the stent. Its use can also shorten the procedure time and reduce the contrast agent dose and radiation exposure, making it a valuable tool fo…
View article: Evaluation of 3-dimensional rotational venography for the diagnosis of non-thrombotic iliac venous lesion
Evaluation of 3-dimensional rotational venography for the diagnosis of non-thrombotic iliac venous lesion Open
Background The purpose of this study was to determine the technical feasibility and safety of 3D rotational venography (3D-RV) in the diagnosis of non-thrombotic iliac vein lesions compared with traditional 2D-digital subtraction angiograp…
View article: Computed tomography-guided 125 I radioactive-seed implantation therapy for skull metastasis from hepatocellular carcinoma
Computed tomography-guided 125 I radioactive-seed implantation therapy for skull metastasis from hepatocellular carcinoma Open
View article: Robot-assisted retroperitoneal approach to retrieve inferior vena cava filter
Robot-assisted retroperitoneal approach to retrieve inferior vena cava filter Open
View article: Overwork Death of Chinese Physicians under High-Intensity Pressure, 2007-2018
Overwork Death of Chinese Physicians under High-Intensity Pressure, 2007-2018 Open
Background: To summarize the cases of physicians overwork death between Jan 2007 and Dec 2018, the tragedy merits the attention of the authorities and policy-makers to increase their efforts to reduce death among physicians in China. Metho…