Yingting Pang
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View article: Locomotor Hyperactivity in the Early-Stage Alzheimer’s Disease-like Pathology of APP/PS1 Mice: Associated with Impaired Polarization of Astrocyte Aquaporin 4
Locomotor Hyperactivity in the Early-Stage Alzheimer’s Disease-like Pathology of APP/PS1 Mice: Associated with Impaired Polarization of Astrocyte Aquaporin 4 Open
Non-cognitive behavioral and psychological symptoms often occur in Alzheimer's disease (AD) patients and mouse models, although the exact neuropathological mechanism remains elusive. Here, we report hyperactivity with significant inter-ind…
View article: Pulmonary B Lymphocytes Ameliorate Alzheimer's Disease-Like Neuropathology
Pulmonary B Lymphocytes Ameliorate Alzheimer's Disease-Like Neuropathology Open
Increasing evidences reveal that the peripheral immune system is involved in the pathogenesis of Alzheimer's disease (AD). Here, we report that pulmonary B lymphocytes mitigate beta-Amyloid (Aβ) pathology in 5xFAD mice. The proportion of B…
View article: A water-reward task assay for evaluating mouse mutualistic cooperative behavior
A water-reward task assay for evaluating mouse mutualistic cooperative behavior Open
Social cooperation is fundamentally important for group animals but rarely studied with mice because of their natural aggressiveness. In the present work, we induced pairs of mice to develop a mutualistic cooperative behavior in a non-divi…
View article: Early growth response 2 regulates mouse cooperative behavior
Early growth response 2 regulates mouse cooperative behavior Open
Social cooperation is essential to animals’ physical health and psychological state. However, the underlying molecular and neurobiological mechanisms remain poorly understood. Here, we established a novel model for systematically evaluatin…
View article: Pulmonary B cells ameliorate Alzheimer’s disease-like neuropathology
Pulmonary B cells ameliorate Alzheimer’s disease-like neuropathology Open
Increasing evidence shows that the peripheral immune system is involved in the pathogenesis of Alzheimer’s disease (AD). Here, we report that pulmonary B cells mitigate beta-Amyloid (Aβ) pathology in 5xFAD mice. The proportion of B cells r…