Yingyi Guo
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View article: Association of lipid accumulation product, visceral adiposity index and endometriosis: A cross-sectional study from the 1999–2006 NHANES
Association of lipid accumulation product, visceral adiposity index and endometriosis: A cross-sectional study from the 1999–2006 NHANES Open
Introduction: Endometriosis (EMS) is a common gynaecological disorder linked to metabolic disturbances. However, evidence on the associations between lipid accumulation product (LAP) and visceral adiposity index (VAI) with the risk of EMS …
View article: Comparison of the in vitro activities and resistance mechanisms against imipenem–relebactam and ceftazidime–avibactam in clinical KPC-producing Klebsiella pneumoniae isolated in China
Comparison of the in vitro activities and resistance mechanisms against imipenem–relebactam and ceftazidime–avibactam in clinical KPC-producing Klebsiella pneumoniae isolated in China Open
View article: Overexpression of KPC contributes to ceftazidime-avibactam heteroresistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae
Overexpression of KPC contributes to ceftazidime-avibactam heteroresistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae Open
Ceftazidime–avibactam (CZA) is one of the effective antibiotics used for the treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections, but its resistance rate has increased recently. Previous studies have focused on the me…
View article: Ceftazidime-avibactam resistance in KPC-producing Klebsiella pneumoniae accompanied hypermucoviscosity acquisition
Ceftazidime-avibactam resistance in KPC-producing Klebsiella pneumoniae accompanied hypermucoviscosity acquisition Open
View article: Comparison of antimicrobial activities and resistance mechanisms of eravacycline and tigecycline against clinical Acinetobacter baumannii isolates in China
Comparison of antimicrobial activities and resistance mechanisms of eravacycline and tigecycline against clinical Acinetobacter baumannii isolates in China Open
Tigecycline (TGC) is currently used to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections, while eravacycline (ERV), a new-generation tetracycline, holds promise as a novel therapeutic option for these infections. However…
View article: Comparison of Hypervirulent and Non-Hypervirulent Carbapenem-Resistant Acinetobacter baumannii Isolated from Bloodstream Infections: Mortality, Potential Virulence Factors, and Combination Therapy In Vitro
Comparison of Hypervirulent and Non-Hypervirulent Carbapenem-Resistant Acinetobacter baumannii Isolated from Bloodstream Infections: Mortality, Potential Virulence Factors, and Combination Therapy In Vitro Open
Hypervirulent carbapenem-resistant Acinetobacter baumannii (hv-CRAB) has emerged in bloodstream infections (BSI). Cases of BSI caused by hv-CRAB (hv-CRAB-BSI) had posed a significant threat to hospitalized patients. In this study, 31 CRAB …
View article: Practice of standardization of CLSI M45 A3 antimicrobial susceptibility testing of Infrequently Isolated or Fastidious Bacteria strains isolated from blood specimens in Guangdong Province 2017–2021
Practice of standardization of CLSI M45 A3 antimicrobial susceptibility testing of Infrequently Isolated or Fastidious Bacteria strains isolated from blood specimens in Guangdong Province 2017–2021 Open
The concentration of antimicrobial agents in environments like water and food has increased rapidly, which led to a rapid increase in antimicrobial resistance levels in the environment. Monitoring of bacterial resistance levels is consider…
View article: Large-scale spatial data visualization method based on augmented reality
Large-scale spatial data visualization method based on augmented reality Open
Background: A task assigned to space exploration satellites involves detecting the physical environment within a certain space. However, space detection data are complex and abstract. These data are not conducive for researchers' visual pe…
View article: Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae: Risk Factors and Economic Burden Among Patients with Bloodstream Infections
Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae: Risk Factors and Economic Burden Among Patients with Bloodstream Infections Open
Patients with BSI due to ESBL-producing ESBL-EK incur higher costs compared to those with non-ESBL-EK BSI. This cost disparity is rooted in varying rates of effective empirical antimicrobial therapy and differences in hospital stay duratio…
View article: Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone
Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone Open
View article: Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Guangzhou, China: risk factors and economic burden among Patients with bloodstream infections
Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Guangzhou, China: risk factors and economic burden among Patients with bloodstream infections Open
Background. Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae (ESBL-EK) are important sources of bloodstream infection (BSI), but their economic impact has not been comprehensively evaluated. Patients and m…
View article: Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Guangzhou, China: risk factors and economic burden among Patients with bloodstream infections
Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Guangzhou, China: risk factors and economic burden among Patients with bloodstream infections Open
Background. Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae (ESBL-EK) are important sources of bloodstream infection (BSI), but their economic impact has not been comprehensively evaluated. Patients and m…
View article: Extended-Spectrum β-Lactamase Genes Traverse the Escherichia coli Populations of Intensive Care Unit Patients, Staff, and Environment
Extended-Spectrum β-Lactamase Genes Traverse the Escherichia coli Populations of Intensive Care Unit Patients, Staff, and Environment Open
ESBL resistance significantly impacts clinical management of E. coli infections in hospitals globally. It is important to understand the structures of ESBL-EC populations carried by hospital patients and staff, their capacity to persist in…
View article: Antibiotic Prescription Patterns for Acute Respiratory Infections in Rural Primary Healthcare Settings in Guangdong, China: Analysis of 162,742 Outpatient Prescriptions
Antibiotic Prescription Patterns for Acute Respiratory Infections in Rural Primary Healthcare Settings in Guangdong, China: Analysis of 162,742 Outpatient Prescriptions Open
Overuse and inappropriate use of antibiotics are important contributors to bacterial antimicrobial resistance (AMR), especially in ambulatory primary healthcare (PHC) settings in low- and middle-income countries. This study aimed to invest…
View article: Adaptive Evolution Compensated for the Plasmid Fitness Costs Brought by Specific Genetic Conflicts
Adaptive Evolution Compensated for the Plasmid Fitness Costs Brought by Specific Genetic Conflicts Open
New Delhi metallo-β-lactamase (NDM)-carrying IncX3 plasmids is important in the transmission of carbapenem resistance in Escherichia coli. Fitness costs related to plasmid carriage are expected to limit gene exchange; however, the causes o…
View article: Extended-spectrum β-lactamase genes traverse the<i>Escherichia coli</i>populations of ICU patients, staff and environment
Extended-spectrum β-lactamase genes traverse the<i>Escherichia coli</i>populations of ICU patients, staff and environment Open
Over a three-month period, we monitored the population of extended-spectrum β-lactam-resistant Escherichia coli (ESBL-EC) associated with the patients, staff and environment of an intensive care unit (ICU) in Guangzhou, China. Thirty-four …
View article: Colonization with Carbapenem-Resistant Enterobacteriaceae Contributes to Unfavorable Outcomes in End-Stage Liver Disease Patients
Colonization with Carbapenem-Resistant Enterobacteriaceae Contributes to Unfavorable Outcomes in End-Stage Liver Disease Patients Open
Carbapenem-resistant Enterobacteriaceae (CRE) are the highest priority pathogens of the World Health Organization, and their prevalence in end-stage liver disease (ESLD) patients is increasing. CRE colonization is an independent risk facto…
View article: In silico Evolution and Comparative Genomic Analysis of IncX3 Plasmids Isolated From China Over Ten Years
In silico Evolution and Comparative Genomic Analysis of IncX3 Plasmids Isolated From China Over Ten Years Open
IncX3 plasmids are correlated with the dissemination and acquisition of carbapenem resistance in Enterobacteriaceae and have been prevalent in China over the last 10 years. Since the distribution characteristics of IncX3 plasmids across Ch…
View article: Incidence and Characteristics of Co-infection and Secondary Infection in Patients with COVID-19
Incidence and Characteristics of Co-infection and Secondary Infection in Patients with COVID-19 Open
Objective The etiology and epidemiology of co-infection and secondary infection in COVID-19 patients remain unknown. The study aims to investigate the occurrence and characteristics of co-infection and secondary infection in COVID-19 patie…
View article: Mutations in porin LamB contribute to ceftazidime-avibactam resistance in KPC-producing Klebsiella <i>pneumoniae</i>
Mutations in porin LamB contribute to ceftazidime-avibactam resistance in KPC-producing Klebsiella <i>pneumoniae</i> Open
Ceftazidime-avibactam (CAZ-AVI) shows promising activity against carbapenem-resistant Klebsiella pneumoniae (CRKP), however, CAZ-AVI resistance have emerged recently. Mutations in KPCs, porins OmpK35 and/or OmpK36, and PBPs are known to co…
View article: A systematic review of the effectiveness and safety of Chinese herbal medicine formula Gualou Xiebai Banxia (GLXBBX) decoction for the treatment of stable angina pectoris
A systematic review of the effectiveness and safety of Chinese herbal medicine formula Gualou Xiebai Banxia (GLXBBX) decoction for the treatment of stable angina pectoris Open
Background: A growing number of studies suggest that Gualou Xiebai Banxia (GLXBBX) decoction, a well-known Chinese herbal formula, has beneficial effects on eliminating angina pectoris symptoms and improving condition of stable angina pect…