Yingying Mao
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View article: Smartphone-based nanozyme immunosensor for rapid quantification of rabies neutralizing antibody
Smartphone-based nanozyme immunosensor for rapid quantification of rabies neutralizing antibody Open
The level of rabies virus neutralizing antibody (RVNA) is a critical indicator to evaluate the protective immunity of vaccinees against rabies virus (RABV) infection. The fluorescent antibody virus neutralization test (FAVN) and the rapid …
View article: Factors affecting survival in patients with colorectal cancer: an umbrella review
Factors affecting survival in patients with colorectal cancer: an umbrella review Open
View article: Metabolic signatures for gastric cancer diagnosis and mechanistic insights: a multicenter study
Metabolic signatures for gastric cancer diagnosis and mechanistic insights: a multicenter study Open
Early detection of gastric cancer (GC) is critical for improving prognosis, yet conventional biomarkers lack sensitivity and specificity, necessitating non-invasive, high-performance diagnostic tools. This study integrated untargeted metab…
View article: Association between dietary carbohydrate intake and multiple sclerosis risk: a large-scale cohort study
Association between dietary carbohydrate intake and multiple sclerosis risk: a large-scale cohort study Open
Introduction Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by neuroinflammation and demyelination. Although diet may influence MS risk, evidence regarding carbohydrate intake remains unclear. Methods We examined th…
View article: Association between carbohydrate intake and the risk of psoriasis: a prospective cohort study based on UK Biobank
Association between carbohydrate intake and the risk of psoriasis: a prospective cohort study based on UK Biobank Open
Intake of total sugars, free sugar, and sucrose was positively associated with psoriasis risk, while fiber and starch were inversely associated.
View article: Incidence and prevalence of gout in Eastern China from 2011 to 2021: a retrospective population-based study
Incidence and prevalence of gout in Eastern China from 2011 to 2021: a retrospective population-based study Open
The incidence and prevalence of gout increased over time, showing age- and gender-specific patterns. The healthcare authorities need to focus on the burden of gout and guide targeted prevention and treatment strategies for gout.
View article: Novel rabies vaccine candidates development based on pseudotyped lentiviral vectors with rabies virus glycoprotein
Novel rabies vaccine candidates development based on pseudotyped lentiviral vectors with rabies virus glycoprotein Open
Rabies, caused by the rabies virus (RABV), remains a global public health issue. Traditional inactivated rabies vaccines are costly, risky, and require multiple doses for post-exposure prophylaxis. The rabies virus glycoprotein (RABV-G), e…
View article: Red cell indices as predictors of cancer risk: findings from a large prospective cohort study
Red cell indices as predictors of cancer risk: findings from a large prospective cohort study Open
View article: Single-dose GC101 gene therapy for spinal muscular atrophy types II and III: an open-label single-arm study
Single-dose GC101 gene therapy for spinal muscular atrophy types II and III: an open-label single-arm study Open
View article: Dietary carbohydrate intake and risks of overall and 21 site-specific cancers: a prospective cohort study
Dietary carbohydrate intake and risks of overall and 21 site-specific cancers: a prospective cohort study Open
Background Cancer is among the world’s top causes of death, and diet plays an important role in cancer risk. However, few studies have addressed a comprehensive atlas that details the connections between dietary carbohydrates and cancer ri…
View article: ABS0133 BIDIRECTIONAL MENDELIAN RANDOMIZATION ANALYSIS REVEALS CAUSAL RELATIONSHIPS BETWEEN IMMUNE TRAITS AND POLYMYALGIA RHEUMATICA
ABS0133 BIDIRECTIONAL MENDELIAN RANDOMIZATION ANALYSIS REVEALS CAUSAL RELATIONSHIPS BETWEEN IMMUNE TRAITS AND POLYMYALGIA RHEUMATICA Open
View article: ABS0114 MENDELIAN RANDOMIZATION STUDY REVEALS CAUSAL ASSOCIATIONS BETWEEN VIRAL INFECTIONS AND RHEUMATOID ARTHRITIS
ABS0114 MENDELIAN RANDOMIZATION STUDY REVEALS CAUSAL ASSOCIATIONS BETWEEN VIRAL INFECTIONS AND RHEUMATOID ARTHRITIS Open
View article: Association of non-phthalate plasticizer exposure during early pregnancy with gestational diabetes mellitus: The potential mediation effect of plasma lipidome
Association of non-phthalate plasticizer exposure during early pregnancy with gestational diabetes mellitus: The potential mediation effect of plasma lipidome Open
View article: Immunotherapy combined with chemotherapy: a promising therapeutic approach in the management of colonic squamous cell carcinoma—a case report
Immunotherapy combined with chemotherapy: a promising therapeutic approach in the management of colonic squamous cell carcinoma—a case report Open
Colorectal squamous cell carcinoma (CSCC) is an exceedingly rare malignancy, accounting for approximately 0.41% of all colorectal cancers. This case report describes a 52-year-old male with a history of chronic bronchitis, varicose vein of…
View article: Comparison of Lactobacillus rhamnosus GG and luxS mutant on gut barrier function of mice challenged with Escherichia coli
Comparison of Lactobacillus rhamnosus GG and luxS mutant on gut barrier function of mice challenged with Escherichia coli Open
Quorum sensing (QS) is an essential pathway for bacterial communication through autoinducers (AIs). The luxS gene involved in QS has been proven to regulate different behavior of Lactobacillus rhamnosus GG (LGG), whereas it is unclear whet…
View article: Overexpression of lncRNA22524 from Dongxiang Wild Rice Reduces Drought and Salt Stress Tolerance in Cultivated Rice
Overexpression of lncRNA22524 from Dongxiang Wild Rice Reduces Drought and Salt Stress Tolerance in Cultivated Rice Open
View article: Proteome-wide Mendelian randomization study of plasma proteins associated with mastitis and prediction of potential candidates from herbal medicine
Proteome-wide Mendelian randomization study of plasma proteins associated with mastitis and prediction of potential candidates from herbal medicine Open
View article: Plasma metabolite biomarker identification study for the early detection of gastric cancer
Plasma metabolite biomarker identification study for the early detection of gastric cancer Open
Background: Gastric cancer (GC) is the fifth most prevalent and the fifth deadliest cancer worldwide, and timely diagnosis of GC contributes to an increased survival rate. However, current detection methods for GC mainly rely on gastroscop…
View article: Facile Fabrication of Hydrophobic Poly(Lactic Acid)/Polydimethylsiloxane/ Octaisobutyl Polyhedral Oligomeric Silsesquioxane Fibers with Excellent Stain-Resistance
Facile Fabrication of Hydrophobic Poly(Lactic Acid)/Polydimethylsiloxane/ Octaisobutyl Polyhedral Oligomeric Silsesquioxane Fibers with Excellent Stain-Resistance Open
View article: The probiotic characteristics of <i>Lactobacillus reuteri</i> ZJ617 and its resistance to <i>Escherichia coli</i> O157:H7 challenge in HFD-fed mice
The probiotic characteristics of <i>Lactobacillus reuteri</i> ZJ617 and its resistance to <i>Escherichia coli</i> O157:H7 challenge in HFD-fed mice Open
A high-fat diet (HFD) increases susceptibility to Escherichia coli colonization in the intestine and raises the risk of intestinal diseases. Lactobacillus reuteri , a commensal bacterium, plays a crucial role in regulating intestinal funct…
View article: Smartphone-Based Nanozyme Immunosensor For Rapid Quantification of Rabies Neutralizing Antibody
Smartphone-Based Nanozyme Immunosensor For Rapid Quantification of Rabies Neutralizing Antibody Open
View article: Exploring the associations of plasma proteins with frailty based on Mendelian randomization
Exploring the associations of plasma proteins with frailty based on Mendelian randomization Open
View article: Air pollution, residential greenspace, and the risk of incident immune thrombocytopenic purpura: a prospective cohort study of 356,482 participants
Air pollution, residential greenspace, and the risk of incident immune thrombocytopenic purpura: a prospective cohort study of 356,482 participants Open
This study investigated the associations of air pollution and residential greenspace with immune thrombocytopenic purpura (ITP) risk, along with their combined effects, in a cohort of 356,482 UK Biobank participants free of ITP at baseline…
View article: Exploring the Association between Plasma Proteins and Frailty Based on Mendelian Randomization and Network Pharmacology
Exploring the Association between Plasma Proteins and Frailty Based on Mendelian Randomization and Network Pharmacology Open
Background Frailty is an emerging global burden of disease, characterized as an age-related clinical syndrome. Recent studies have suggested a potential link between plasma protein levels and the onset of frailty. This study aims to analyz…
View article: Kidney Injury Evoked by Fine Particulate Matter: Risk Factor, Causation, Mechanism and Intervention Study
Kidney Injury Evoked by Fine Particulate Matter: Risk Factor, Causation, Mechanism and Intervention Study Open
Fine particulate matter (PM 2.5 ) is suggested to pose a severe risk to the kidneys by inducing functional degradation and chronic kidney diseases (CKD). This study aims to explore the nephrotoxicity of PM 2.5 exposure and the underlying m…
View article: Dietary Carbohydrates, Genetic Susceptibility, and Gout Risk: A Prospective Cohort Study in the UK
Dietary Carbohydrates, Genetic Susceptibility, and Gout Risk: A Prospective Cohort Study in the UK Open
This study aimed to investigate the associations between carbohydrate intake and gout risk, along with interactions between genetic susceptibility and carbohydrates, and the mediating roles of biomarkers. We included 187,387 participants w…
View article: Association of serum 25-hydroxyvitamin D concentrations with all-cause and cause-specific mortality among individuals with gout and hyperuricemia
Association of serum 25-hydroxyvitamin D concentrations with all-cause and cause-specific mortality among individuals with gout and hyperuricemia Open
Serum 25(OH)D was negatively linearly correlated with mortality among gout patients, whereas U-shaped correlated with mortality in HUA patients. These results indicate that adequate vitamin D status could prevent premature death.
View article: Alcohol consumption and the risk of rheumatoid arthritis
Alcohol consumption and the risk of rheumatoid arthritis Open
Background Though accumulated evidence has indicated an inverse relationship between alcohol intake and rheumatoid arthritis (RA) risk, it remained uncertain whether such association was causal or biased by confounding. We aimed to explore…
View article: Associations of modifiable factors with risk of irritable bowel syndrome
Associations of modifiable factors with risk of irritable bowel syndrome Open
Background Modifiable factors were found to be associated with the risk of irritable bowel syndrome (IBS) in observational studies, but whether these associations are causal is uncertain. We conducted a Mendelian randomization (MR) study t…
View article: Associations of dietary magnesium intake with all-cause and cause-specific mortality among individuals with gout and hyperuricemia
Associations of dietary magnesium intake with all-cause and cause-specific mortality among individuals with gout and hyperuricemia Open
Background: We aimed to evaluate the relationship of dietary magnesium intake with all-cause and cause-specific mortality among patients with gout and hyperuricemia (HUA). Methods: We analyzed data of 1171 gout patients and 6707 patients w…