Yining Lu
YOU?
Author Swipe
View article: Associations of Mycoplasma pneumoniae load, co-infections, and macrolide resistance with clinical-laboratory profiles in hospitalized pediatric pneumonia: A targeted next-generation sequencing(tNGS) study of bronchoalveolar lavage fluid (BALF)
Associations of Mycoplasma pneumoniae load, co-infections, and macrolide resistance with clinical-laboratory profiles in hospitalized pediatric pneumonia: A targeted next-generation sequencing(tNGS) study of bronchoalveolar lavage fluid (BALF) Open
Purpose This study aimed to investigate the associations of Mycoplasma pneumoniae (MP) DNA load, co-infection, and macrolide resistance with clinical phenotypes in pediatric pneumonia, using targeted next-generation sequencing (tNGS) of br…
View article: A Decentralized Retrieval Augmented Generation System with Source Reliabilities Secured on Blockchain
A Decentralized Retrieval Augmented Generation System with Source Reliabilities Secured on Blockchain Open
Existing retrieval-augmented generation (RAG) systems typically use a centralized architecture, causing a high cost of data collection, integration, and management, as well as privacy concerns. There is a great need for a decentralized RAG…
View article: Learning to Optimize Multi-Objective Alignment Through Dynamic Reward Weighting
Learning to Optimize Multi-Objective Alignment Through Dynamic Reward Weighting Open
Prior works in multi-objective reinforcement learning typically use linear reward scalarization with fixed weights, which provably fail to capture non-convex Pareto fronts and thus yield suboptimal results. This limitation becomes especial…
View article: TRAF2 Promotes Liver Fibrosis via Regulation of the HIF-1α/GLUT1-Mediated Glycolysis in Hepatic Stellate Cells
TRAF2 Promotes Liver Fibrosis via Regulation of the HIF-1α/GLUT1-Mediated Glycolysis in Hepatic Stellate Cells Open
Tumor necrosis factor receptor-associated factor 2 (TRAF2) is an intracellular aptamer protein with E3 ligase activity and has been reported to be involved in the pathogenesis of hepatitis and liver cancer. However, the specific mechanism …
View article: Partial femoral head replacement: a new innovative surgical technique for precise minimally invasive treatment of association research circulation osseous stage III femoral head necrosis
Partial femoral head replacement: a new innovative surgical technique for precise minimally invasive treatment of association research circulation osseous stage III femoral head necrosis Open
View article: American academy of Orthopedic Surgeons' OrthoInfo provides more readable information regarding meniscus injury than ChatGPT-4 while information accuracy is comparable
American academy of Orthopedic Surgeons' OrthoInfo provides more readable information regarding meniscus injury than ChatGPT-4 while information accuracy is comparable Open
IV.
View article: American Academy of Orthopaedic Surgeons OrthoInfo provides more readable information regarding rotator cuff injury than ChatGPT
American Academy of Orthopaedic Surgeons OrthoInfo provides more readable information regarding rotator cuff injury than ChatGPT Open
IV.
View article: Graft Failure and Contralateral ACL Injuries After Primary ACL Reconstruction: An Analysis of Risk Factors Using Interpretable Machine Learning
Graft Failure and Contralateral ACL Injuries After Primary ACL Reconstruction: An Analysis of Risk Factors Using Interpretable Machine Learning Open
Background: Anterior cruciate ligament (ACL) reconstruction (ACLR) can be successful in restoring knee stability. However, secondary ACL injury, either through graft failure or contralateral injury, is a known complication and can signific…
View article: Identifying Racial Disparities in Utilization and Clinical Outcomes of Ambulatory Hip Arthroscopy: Analysis of Temporal Trends and Causal Inference via Machine Learning
Identifying Racial Disparities in Utilization and Clinical Outcomes of Ambulatory Hip Arthroscopy: Analysis of Temporal Trends and Causal Inference via Machine Learning Open
Background: Arthroscopic diagnosis and treatment of femoroacetabular pathology has experienced significant growth in the last 30 years; nevertheless, reduced utilization of orthopaedic procedures has been observed among the underrepresente…
View article: Identifying clinically meaningful subgroups following open reduction and internal fixation for proximal humerus fractures: a risk stratification analysis for mortality and 30-day complications using machine learning
Identifying clinically meaningful subgroups following open reduction and internal fixation for proximal humerus fractures: a risk stratification analysis for mortality and 30-day complications using machine learning Open
Unsupervised ML identified that "high-risk" patients have a higher risk of complications (8.9%) than "low-risk" groups (0.4%) with respect to 30-day complication rate. A supervised ML model selected greater body mass index, increasing age,…
View article: Unraveling the genetic basis of the causal association between inflammatory cytokines and osteonecrosis
Unraveling the genetic basis of the causal association between inflammatory cytokines and osteonecrosis Open
Background Previous studies have reported that the occurrence and development of osteonecrosis is closely associated with immune-inflammatory responses. Mendelian randomization was performed to further assess the causal correlation between…
View article: Micro femoral head prosthesis in applications to collapsed femoral head necrosis in the weight-bearing dome (ARCO III): A case series with short-term follow-up
Micro femoral head prosthesis in applications to collapsed femoral head necrosis in the weight-bearing dome (ARCO III): A case series with short-term follow-up Open
Osteonecrosis of the femoral head (ONFH) is mainly caused by a decrease in the vascular supply to the subchondral bone of the femoral head, leading to the death of bone cells, degeneration and necrosis of the subchondral bone, and eventual…
View article: Monocyte alteration in elderly hip fracture healing: monocyte promising role in bone regeneration
Monocyte alteration in elderly hip fracture healing: monocyte promising role in bone regeneration Open
View article: Podium Presentation Title: Is Biologic Augmentation Cost-Effective? PRP and Marrow Venting During Isolated Meniscal Repair
Podium Presentation Title: Is Biologic Augmentation Cost-Effective? PRP and Marrow Venting During Isolated Meniscal Repair Open
View article: GEAR: Augmenting Language Models with Generalizable and Efficient Tool Resolution
GEAR: Augmenting Language Models with Generalizable and Efficient Tool Resolution Open
View article: Deep Learning Artificial Intelligence Tool for Automated Radiographic Determination of Posterior Tibial Slope in Patients With ACL Injury
Deep Learning Artificial Intelligence Tool for Automated Radiographic Determination of Posterior Tibial Slope in Patients With ACL Injury Open
Background: An increased posterior tibial slope (PTS) corresponds with an increased risk of graft failure after anterior cruciate ligament (ACL) reconstruction (ACLR). Validated methods of manual PTS measurements are subject to potential i…
View article: No Differences in Exercise Performance, Perceptual Response, or Safety Were Observed Among 3 Blood Flow Restriction Devices
No Differences in Exercise Performance, Perceptual Response, or Safety Were Observed Among 3 Blood Flow Restriction Devices Open
View article: Risk factors for short-term mortality in elderly hip fracture patients with complicated heart failure in the ICU: A MIMIC-IV database analysis using nomogram
Risk factors for short-term mortality in elderly hip fracture patients with complicated heart failure in the ICU: A MIMIC-IV database analysis using nomogram Open
View article: Nano‐calcipotriol as a potent anti‐hepatic fibrosis agent
Nano‐calcipotriol as a potent anti‐hepatic fibrosis agent Open
Calcipotriol (CAL) has been widely studied as a fibrosis inhibitor and used to treat plaque psoriasis via transdermal administration. The clinical application of CAL to treat liver fibrosis is bottlenecked by its unsatisfactory pharmacokin…
View article: Artificial Intelligence Can Define and Predict the "Optimal Observed Outcome" After Anterior Shoulder Instability Surgery: An Analysis of 200 Patients With 11-Year Mean Follow-Up
Artificial Intelligence Can Define and Predict the "Optimal Observed Outcome" After Anterior Shoulder Instability Surgery: An Analysis of 200 Patients With 11-Year Mean Follow-Up Open
View article: GEAR: Augmenting Language Models with Generalizable and Efficient Tool Resolution
GEAR: Augmenting Language Models with Generalizable and Efficient Tool Resolution Open
Augmenting large language models (LLM) to use external tools enhances their performance across a variety of tasks. However, prior works over-rely on task-specific demonstration of tool use that limits their generalizability and computation…
View article: Paper 44: Deep Learning Artificial Intelligence Tool for Automated Radiographic Determination of Posterior Tibial Slope in Patients with Anterior Cruciate Ligament Injuries
Paper 44: Deep Learning Artificial Intelligence Tool for Automated Radiographic Determination of Posterior Tibial Slope in Patients with Anterior Cruciate Ligament Injuries Open
Objectives: An increased posterior tibial slope (PTS) corresponds with an increased risk of graft failure following anterior cruciate ligament reconstruction (ACLR). Validated methods of human PTS measurements are subject to interobserver …
View article: Poster 362: Identifying Racial Disparity in Utilization and Outcomes of Hip Arthroscopy using Machine Learning
Poster 362: Identifying Racial Disparity in Utilization and Outcomes of Hip Arthroscopy using Machine Learning Open
Objectives: Background: Arthroscopic diagnosis and treatment of femoroacetabular pathology has been increasingly used in the past thirty years with interventions resulting in improved hip function and ultimate delay of hip arthroplasty in …
View article: Poster 179: Unsupervised Machine Learning to Identify Clinically Meaningful Subgroups in Patients Undergoing Arthroscopic Rotator Cuff Repair
Poster 179: Unsupervised Machine Learning to Identify Clinically Meaningful Subgroups in Patients Undergoing Arthroscopic Rotator Cuff Repair Open
Objectives: Rotator cuff tears are estimated to affect 20.7% of the population, with the prevalence increasing with age. Surgery is indicated after non-response to nonoperative treatment, with arthroscopic rotator cuff repair (ARCR) as the…
View article: Paper 43: Defining and Predicting the “Optimal Observed Outcome” Following Surgical Treatment of Anterior Shoulder Instability: A Machine Learning Clustering Analysis of 200 patients with 11-year mean follow up.
Paper 43: Defining and Predicting the “Optimal Observed Outcome” Following Surgical Treatment of Anterior Shoulder Instability: A Machine Learning Clustering Analysis of 200 patients with 11-year mean follow up. Open
Objectives: Desirable outcomes following surgery for anterior shoulder instability (ASI) include a multitude of functional and clinical functions, yet it remains uncertain if all of these outcomes are simultaneously achievable (i.e. can pa…
View article: Associations between dairy consumption, physical activity, and blood pressure in Chinese young women
Associations between dairy consumption, physical activity, and blood pressure in Chinese young women Open
Introduction The prevalence of hypertension (HTN) has been increasing in young adults. A healthy dietary pattern and increasing physical activity (PA) are commonly recommended as lifestyle modifications needed to manage blood pressure (BP)…
View article: Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE<sup>-/-</sup>mice
Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE<sup>-/-</sup>mice Open
Background: Atherosclerosis (AS) is still the major cause of cardiovascular disease (CVD) as well as stroke. Endothelial metabolic disorder has been found to be activated and then promote endothelial cells (ECs) injury, which is reg…
View article: ProtSi: Prototypical Siamese Network with Data Augmentation for Few-Shot Subjective Answer Evaluation
ProtSi: Prototypical Siamese Network with Data Augmentation for Few-Shot Subjective Answer Evaluation Open
Subjective answer evaluation is a time-consuming and tedious task, and the quality of the evaluation is heavily influenced by a variety of subjective personal characteristics. Instead, machine evaluation can effectively assist educators in…
View article: Neuroanatomical substrates in Parkinson’s Disease psychosis and their association with serotonergic receptor gene expression: A coordinate-based meta-regression analysis
Neuroanatomical substrates in Parkinson’s Disease psychosis and their association with serotonergic receptor gene expression: A coordinate-based meta-regression analysis Open
Background Common neural underpinning of Parkinson’s Disease (PD) psychosis across different structural magnetic resonance imaging (MRI) studies remains unclear to this day with few studies and even fewer meta-analyses available. Objective…
View article: Early ACLR and Risk and Timing of Secondary Meniscal Injury Compared With Delayed ACLR or Nonoperative Treatment: A Time-to-Event Analysis Using Machine Learning
Early ACLR and Risk and Timing of Secondary Meniscal Injury Compared With Delayed ACLR or Nonoperative Treatment: A Time-to-Event Analysis Using Machine Learning Open
Background: Surgical and nonoperative management of anterior cruciate ligament (ACL) injuries seek to mitigate the risk of knee instability and secondary meniscal injury. However, the associated risk and timing of secondary meniscal tears …