Yi-Feng Xu
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View article: Direct circMAN1A2(2,3,4,5)-CENPB mRNA interaction regulates cell proliferation and cancer progression
Direct circMAN1A2(2,3,4,5)-CENPB mRNA interaction regulates cell proliferation and cancer progression Open
View article: Design of Wearable Intelligent Pulse Detection System Based on Flexible Sensors
Design of Wearable Intelligent Pulse Detection System Based on Flexible Sensors Open
The pulse serves as an early indicator of metabolic disorders and provides a measure of cardiovascular and pulmonary function. Monitoring pulse activity can help detect and prevent cardiovascular diseases and related conditions. Advances i…
View article: InterIDEAS: Philosophical Intertextuality via LLMs
InterIDEAS: Philosophical Intertextuality via LLMs Open
View article: Using <i>sno-</i> <i>lncRNAs</i> as potential markers for Prader-Willi syndrome diagnosis
Using <i>sno-</i> <i>lncRNAs</i> as potential markers for Prader-Willi syndrome diagnosis Open
The genetic disorder Prader-Willi syndrome (PWS) is mainly caused by the loss of multiple paternally expressed genes in chromosome 15q11-q13 (the PWS region). Early diagnosis of PWS is essential for timely treatment, leading to effectively…
View article: Using <i>sno-</i><i>lncRNAs</i> as potential markers for Prader-Willi syndrome diagnosis
Using <i>sno-</i><i>lncRNAs</i> as potential markers for Prader-Willi syndrome diagnosis Open
The genetic disorder Prader-Willi syndrome (PWS) is mainly caused by the loss of multiple paternally expressed genes in chromosome 15q11-q13 (the PWS region). Early diagnosis of PWS is essential for timely treatment, leading to effectively…
View article: RNA circles with minimized immunogenicity as potent PKR inhibitors
RNA circles with minimized immunogenicity as potent PKR inhibitors Open
View article: 895 Discovery of a safer 4–1BB agonist by targeting a membrane-proximal epitope combined with bispecific-mediated cross-bridging
895 Discovery of a safer 4–1BB agonist by targeting a membrane-proximal epitope combined with bispecific-mediated cross-bridging Open
Background Checkpoint inhibitors towards cytotoxic T-lymphocyte protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) have paved the way for a new frontier of anti-cancer therapies that modulate our pre-existing immune system to fi…
View article: Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells
Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells Open
View article: A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy
A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy Open
In the absence of a proven effective vaccine preventing infection by SARS-CoV-2, or a proven drug to treat COVID-19, the positive results of passive immune therapy using convalescent serum provide a strong lead. We have developed a new cla…
View article: Anaphase-promoting complex/cyclosome regulates RdDM activity by degrading DMS3 in <i>Arabidopsis</i>
Anaphase-promoting complex/cyclosome regulates RdDM activity by degrading DMS3 in <i>Arabidopsis</i> Open
During RNA-directed DNA methylation (RdDM), the DDR complex, composed of DRD1, DMS3, and RDM1, is responsible for recruiting DNA polymerase V (Pol V) to silence transposable elements (TEs) in plants. However, how the DDR complex is regulat…
View article: Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast
Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast Open
Starvation of diploid cells of the budding yeast Saccharomyces cerevisiae induces them to enter meiosis and differentiate into haploid spores. During meiosis, the precise timing of gene expression is controlled at the level of transcriptio…