Yipeng Ge
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View article: The dual challenges of urbanization and ecological protection: a new path for optimizing ecological patterns in semi-humid areas
The dual challenges of urbanization and ecological protection: a new path for optimizing ecological patterns in semi-humid areas Open
In semi-humid regions, urban expansion and uneven water distribution cause ecological stress, especially under water scarcity. Establishing ecological security patterns aids ecosystem restoration. Unlike hierarchical approaches, this study…
View article: Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study
Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study Open
Background The difference between cystatin C- and creatinine-based estimated glomerular filtration rate (eGFR diff ) is closely associated with various adverse outcomes. This study aims to comprehensively evaluate the association between e…
View article: Pgk1 activation restores endothelial metabolic homeostasis to alleviate vascular aging and atherosclerosis
Pgk1 activation restores endothelial metabolic homeostasis to alleviate vascular aging and atherosclerosis Open
View article: Dietary inflammatory potential, genetic susceptibility, and systemic inflammation indices in relation to abdominal aortic aneurysm risk: a prospective cohort study
Dietary inflammatory potential, genetic susceptibility, and systemic inflammation indices in relation to abdominal aortic aneurysm risk: a prospective cohort study Open
Background Chronic inflammation and genetic susceptibility are important factors in abdominal aortic aneurysm (AAA) pathogenesis, yet evidence regarding the impact of dietary inflammation on AAA risk remains limited. This study aimed to in…
View article: PDGFRα <sup>+</sup> DPP4 <sup>+</sup> Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway
PDGFRα <sup>+</sup> DPP4 <sup>+</sup> Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway Open
Thyroid eye disease (TED), the leading adult orbital disease, is an autoimmune disorder characterized by fibrosis. Effective anti‐fibrotic treatments are scarce, except for orbital decompression surgery involving orbital adipose tissue (OA…
View article: Spatial identification and corridor network analysis of cultural heritage based on multi-model fusion: A case study of western Henan
Spatial identification and corridor network analysis of cultural heritage based on multi-model fusion: A case study of western Henan Open
View article: Prospective analysis of metabolic syndrome and inflammation in aortic aneurysm risk: UK Biobank study
Prospective analysis of metabolic syndrome and inflammation in aortic aneurysm risk: UK Biobank study Open
Context/Objectives Metabolic syndrome (MetS) is associated with various diseases, yet its connection with aortic aneurysm (AA) is not well understood. The role of chronic inflammation as a mediator in this relationship also remains unclear…
View article: Study on the Distribution Characteristics and Cultural Landscape Zoning of Traditional Villages in North Henan Province
Study on the Distribution Characteristics and Cultural Landscape Zoning of Traditional Villages in North Henan Province Open
Traditional villages contain rich natural and humanistic information, and exploring the spatial distribution characteristics and cultural landscape zoning of traditional villages can provide scientific support for their centralized and con…
View article: Association of Shift Work and Lifestyle With Aortic Aneurysm Incidence: A Large Prospective Cohort Study in the UK Biobank
Association of Shift Work and Lifestyle With Aortic Aneurysm Incidence: A Large Prospective Cohort Study in the UK Biobank Open
Background Shift work is associated with various health problems, but its impact on aortic aneurysm (AA) is unclear. The role of lifestyle factors in this regard is also less clear. This study aimed to explore the combined effects of shift…
View article: Oral hypoglycemic drugs mediated the protective effect from type 2 diabetes on aortic aneurysm and aortic dissection
Oral hypoglycemic drugs mediated the protective effect from type 2 diabetes on aortic aneurysm and aortic dissection Open
Background Aortic disease is a series of life-threatening cardiovascular diseases, including aortic dissection (AD) and aortic aneurysm (AA). Rupture of the aorta is the main cause of death for AA and AD, the estimated global death rate re…
View article: A TLK2-mediated calcium-driven cell death pathway links neuronal degeneration to nuclear envelope disruption
A TLK2-mediated calcium-driven cell death pathway links neuronal degeneration to nuclear envelope disruption Open
Calcium overload drives neuronal cell death, but its mechanisms remain unclear. Previous studies in Drosophila implicated tousled-like kinase (TLK) in this process. Here, we investigated TLK2, the mammalian homolog, in calcium overload-ind…
View article: Relationship between perioperative plasma neutrophil gelatinase-associated lipocalin level and acute kidney injury after acute type A aortic dissection
Relationship between perioperative plasma neutrophil gelatinase-associated lipocalin level and acute kidney injury after acute type A aortic dissection Open
The perioperative levels of plasma NGAL in patients who developed AKI after ATAAD were notably elevated compared to those without AKI. Furthermore, plasma NGAL demonstrated strong predictive capability for severe postoperative AKI.
View article: A study on the relationship between internet popularity and emotional perception of urban parks using Weibo data in Luoyang, China
A study on the relationship between internet popularity and emotional perception of urban parks using Weibo data in Luoyang, China Open
The role of Internet Popularity (INPY) in shaping public perception of urban parks is increasingly significant. Although existing studies have explored the impact of parks on public perception, they primarily focus on traditional environme…
View article: Identification of the Hub Gene <scp>LDB3</scp> in Stanford Type A Aortic Dissection Based on Comprehensive Bioinformatics Analysis
Identification of the Hub Gene <span>LDB3</span> in Stanford Type A Aortic Dissection Based on Comprehensive Bioinformatics Analysis Open
Stanford type A aortic dissection (TAAD) is a life‐threatening disease. This study explored the role of LIM domain binding 3 (LDB3) in TAAD progression. Four datasets from the Gene Expression Omnibus were analyzed to identify TAAD‐related …
View article: Aortic arch-clamping technique without open distal anastomosis for extended ascending aortic aneurysms
Aortic arch-clamping technique without open distal anastomosis for extended ascending aortic aneurysms Open
Considering its short- and mid-term efficacy, the AAC technique is an alternative technique for extended ascending aneurysms.
View article: A Study on the Spatial, Structural, and Cultural Differentiation of Traditional Villages in Western Henan Using Geographic Detectors and ArcGIS
A Study on the Spatial, Structural, and Cultural Differentiation of Traditional Villages in Western Henan Using Geographic Detectors and ArcGIS Open
Traditional villages are an important cultural heritage left by China’s agrarian civilization and serve as a testament to the historical development of the Chinese nation. The study of spatial and cultural differentiation in traditional vi…
View article: Spatial Vitality Detection and Evaluation in Zhengzhou’s Main Urban Area
Spatial Vitality Detection and Evaluation in Zhengzhou’s Main Urban Area Open
Urban vitality is a concept that reflects dynamic changes in economic, social, and cultural aspects, emphasizing the importance of diversified land use and dense population. With technological advancements, research methods on urban vitali…
View article: Ecosystem Services and Public Perception of Green Infrastructure from the Perspective of Urban Parks: A Case Study of Luoyang City, China
Ecosystem Services and Public Perception of Green Infrastructure from the Perspective of Urban Parks: A Case Study of Luoyang City, China Open
As one form of urban green infrastructure, city parks provide essential ecosystem services and serve as a vital link connecting citizens with natural ecosystems. The public, as the primary beneficiaries of urban park ecosystem services, pl…
View article: A Study on the Internet Popularity and Emotional Perception Evaluation of Urban Green Spaces Based on Weibo Check-In Data: A Case Study of Luoyang, China
A Study on the Internet Popularity and Emotional Perception Evaluation of Urban Green Spaces Based on Weibo Check-In Data: A Case Study of Luoyang, China Open
View article: IL-6 signaling accelerates iron overload by upregulating DMT1 in endothelial cells to promote aortic dissection
IL-6 signaling accelerates iron overload by upregulating DMT1 in endothelial cells to promote aortic dissection Open
Aortic dissection (AD), caused by tearing of the intima and avulsion of the aortic media, is a severe threat to patient life and organ function. Iron is closely related to dissection formation and organ injury, but the mechanism of iron io…
View article: Surgical management and outcomes of coronary artery involvement secondary to acute type A aortic dissection: a retrospective cohort study
Surgical management and outcomes of coronary artery involvement secondary to acute type A aortic dissection: a retrospective cohort study Open
For patients with ATAAD undergoing TAR and FET implantation, concomitant CAI may complicate surgery and increase in-hospital morbidity and mortality. CAM secondary to CAI was identified as an independent risk factor. However, short-term su…
View article: Anzhen Risk Evaluation System for Acute Aortic Syndrome (AZSCORE-AAS): protocol for a multicentre prospective cohort study in northern China
Anzhen Risk Evaluation System for Acute Aortic Syndrome (AZSCORE-AAS): protocol for a multicentre prospective cohort study in northern China Open
Introduction Acute aortic syndrome (AAS) is a group of acute and critical conditions, including acute aortic dissection (AAD), acute intramural haematoma and penetrating aortic ulcer. High mortality and morbidity rates result in a poor pat…
View article: Aortic Arch-clamping Technique in Total Arch Replacement and Frozen Elephant Trunk for Acute Type A Aortic Dissection
Aortic Arch-clamping Technique in Total Arch Replacement and Frozen Elephant Trunk for Acute Type A Aortic Dissection Open
OBJECTIVES Moderate hypothermic circulatory arrest (MHCA) with selective antegrade cerebral perfusion (SACP) is safe and efficient in total arch replacement and frozen elephant trunk (TAR and FET) for acute type A aortic dissection (ATAAD)…
View article: Redo Total Aortic Arch Replacement in Patients with Aortic Dissection After Open-Heart Surgery and Long-Term Follow-Up Results
Redo Total Aortic Arch Replacement in Patients with Aortic Dissection After Open-Heart Surgery and Long-Term Follow-Up Results Open
Introduction: The objectives of this study were to investigate the main treatment strategies and long-term follow-up results of aortic dissection surgery after open-heart surgery (ADSOHS) and to analyze the risk factors that cause ADSOHS. …
View article: The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol
The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol Open
Introduction: Acute type A aortic dissection (ATAAD) is a catastrophic disease with fatal outcomes. Malperfusion syndrome (MPS) is a serious complication of ATAAD, with an incidence of 20–40%. Many studies have shown that MPS is the main r…
View article: Redo Total Aortic Arch Replacement in Patients with Aortic Dissection After Open-Heart Surgery and Long-Term Follow-Up Results
Redo Total Aortic Arch Replacement in Patients with Aortic Dissection After Open-Heart Surgery and Long-Term Follow-Up Results Open
ADSOHS treatment strategy is of high application value, and the risk of neurological complications and mortality is low. The main risk factors are postoperative low cardiac output, coma, stroke, and transient neurological dysfunction. The …
View article: Development and validation of a nomogram for postoperative severe acute kidney injury in acute type A aortic dissection.
Development and validation of a nomogram for postoperative severe acute kidney injury in acute type A aortic dissection. Open
We developed a prognostic model including age, cardiopulmonary bypass time, serum creatinine, and D-dimer to predict severe AKI after AAAD surgery. The prognostic model demonstrated an effective predictive capability for severe AKI, which …
View article: Sufentanil: a risk factor for lactic acidosis in patients after heart valve surgery
Sufentanil: a risk factor for lactic acidosis in patients after heart valve surgery Open
Backgrounds Hyperlactatemia is a common metabolic disorder after cardiac surgery with cardiopulmonary bypass. Epinephrine use has been identified as a potential cause of increased lactate levels after cardiac surgery. Stress can lead to an…
View article: Massive Bleeding After Surgical Repair in Acute Type A Aortic Dissection Patients: Risk Factors, Outcomes, and the Predicting Model
Massive Bleeding After Surgical Repair in Acute Type A Aortic Dissection Patients: Risk Factors, Outcomes, and the Predicting Model Open
Background Massive bleeding throughout aortic repair in acute type A aortic dissection (ATAAD) patients is a common but severe condition that can cause multiple serious clinical problems. Here, we report our findings regarding risk factors…
View article: Blood Transfusion Predicts Prolonged Mechanical Ventilation in Acute Stanford Type A Aortic Dissection Undergoing Total Aortic Arch Replacement
Blood Transfusion Predicts Prolonged Mechanical Ventilation in Acute Stanford Type A Aortic Dissection Undergoing Total Aortic Arch Replacement Open
Background This research aimed to evaluate the impacts of transfusing packed red blood cells (pRBCs), fresh frozen plasma (FFP), or platelet concentrate (PC) on postoperative mechanical ventilation time (MVT) in patients with acute Stanfor…