Yi‐Ping Phoebe Chen
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View article: Metabolic Reprogramming in Lung Cancer: Hallmarks, Mechanisms, and Targeted Strategies to Overcome Immune Resistance
Metabolic Reprogramming in Lung Cancer: Hallmarks, Mechanisms, and Targeted Strategies to Overcome Immune Resistance Open
Background Lung cancer remains the leading cause of cancer‐related mortality worldwide. Although immunotherapy has revolutionized lung cancer treatment, its efficacy is often hindered by primary and acquired immune resistance. Increasing e…
View article: ARCO-BO: Adaptive Resource-aware COllaborative Bayesian Optimization for Heterogeneous Multi-Agent Design
ARCO-BO: Adaptive Resource-aware COllaborative Bayesian Optimization for Heterogeneous Multi-Agent Design Open
Modern scientific and engineering design increasingly involves distributed optimization, where agents such as laboratories, simulations, or industrial partners pursue related goals under differing conditions. These agents often face hetero…
View article: CLTDA: Identifying Associations Between tsRNAs and Diseases Based on Contrastive Learning
CLTDA: Identifying Associations Between tsRNAs and Diseases Based on Contrastive Learning Open
Increasing evidences have highlighted the significant association between tsRNAs and diseases. Predicting potential tsRNA-disease associations based on computational methods can effectively reduce human and resource consumption. However, t…
View article: Radical radiation therapy for esophageal carcinoma in situs inversus totalis with the history of surgery for lung cancer: a case report
Radical radiation therapy for esophageal carcinoma in situs inversus totalis with the history of surgery for lung cancer: a case report Open
Situs inversus totalis (SIT) is a rare congenital anatomical variation. This case report describes the first instance of a patient with both lung and esophageal cancer along with SIT. Additionally, it presents the first successful radical …
View article: A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis
A trans-kingdom T6SS RNase effector targeting both prokaryotic and host cells for pathogenesis Open
View article: Construction and optimization of video-triggered cases in problem-based learning
Construction and optimization of video-triggered cases in problem-based learning Open
Objectives Problem-based learning (PBL) is widely used in medicine instruction worldwide. Little research has been done on video-triggered cases in medical education in China. The aim of this study is to determine whether video-triggered c…
View article: Effects of a positive psychological intervention on psychological states and functional brain imaging of nurses in transition training: a quasi-experimental study
Effects of a positive psychological intervention on psychological states and functional brain imaging of nurses in transition training: a quasi-experimental study Open
Objective To explore the effects of a positive psychological intervention on the psychological state and brain function of trained nurses during the transition period. Methods Randomization was used to assign 130 trained nurses to the obse…
View article: GA-S$^3$: Comprehensive Social Network Simulation with Group Agents
GA-S$^3$: Comprehensive Social Network Simulation with Group Agents Open
Social network simulation is developed to provide a comprehensive understanding of social networks in the real world, which can be leveraged for a wide range of applications such as group behavior emergence, policy optimization, and busine…
View article: Investigation of Frequency Response Sharing-Induced Power Oscillations in VSC-HVDC Systems for Asynchronous Interconnection
Investigation of Frequency Response Sharing-Induced Power Oscillations in VSC-HVDC Systems for Asynchronous Interconnection Open
Low-frequency power oscillations (LFPOs) may occur in voltage source converter-based high-voltage direct current (VSC-HVDC) systems when providing frequency support to asynchronously interconnected power grids. This phenomenon has been obs…
View article: HunyuanVideo-Avatar: High-Fidelity Audio-Driven Human Animation for Multiple Characters
HunyuanVideo-Avatar: High-Fidelity Audio-Driven Human Animation for Multiple Characters Open
Recent years have witnessed significant progress in audio-driven human animation. However, critical challenges remain in (i) generating highly dynamic videos while preserving character consistency, (ii) achieving precise emotion alignment …
View article: Oxygen nanobubble-induced hyperoxia: Effects on growth, digestive enzyme activity, intestinal morphology, and biochemical parameters in kuruma prawn (Penaeus japonicus)
Oxygen nanobubble-induced hyperoxia: Effects on growth, digestive enzyme activity, intestinal morphology, and biochemical parameters in kuruma prawn (Penaeus japonicus) Open
View article: Temporal Coherent Object Flow for Multi-Object Tracking
Temporal Coherent Object Flow for Multi-Object Tracking Open
Multi-object tracking is a challenging vision task that requires simultaneous reasoning about object detection and object association. Conventional solutions use frame as the basic unit and typically rely on a motion predictor that exploit…
View article: Discovery of Zoanthamine Alkaloids from <i>Zoanthus vietnamensis</i> with Antioxidant and Neuroprotective Activities
Discovery of Zoanthamine Alkaloids from <i>Zoanthus vietnamensis</i> with Antioxidant and Neuroprotective Activities Open
Two novel alkaloids, zoanides A and B (1 and 2), 12 new zoanthamine-type alkaloids (3-14), together with two known compounds (15 and 16) were obtained from the zoantharian Zoanthus vietnamensis<…
View article: The Discovery and Development of KH607 as a Treatment for Postpartum Depression(PPD)and Major Depressive Disorder (MDD)
The Discovery and Development of KH607 as a Treatment for Postpartum Depression(PPD)and Major Depressive Disorder (MDD) Open
Introduction Depression is a serious CNS-related disease that may require long-term treatment. Postpartum depression is a critical medical condition that affects the mother, as well as has a short and long-term impact on the growth of the …
View article: Factors influencing accessibility of palliative care: a systematic review and meta-analysis
Factors influencing accessibility of palliative care: a systematic review and meta-analysis Open
View article: Optimized agricultural site selection based on geographic similarity
Optimized agricultural site selection based on geographic similarity Open
In this study, we proposed an optimal agricultural site selection method based on the third law of geography and geographic similarity, and took the vegetable moss growing area in Hongshan District, Wuhan, China, as an example. The geograp…
View article: Numerical simulation analysis of pile-soil interaction under earthquake action
Numerical simulation analysis of pile-soil interaction under earthquake action Open
Pile foundation is a commonly recognized form of foundation, and earthquakes are a common seismic damage phenomenon. Accidents resulting from reduction in pile bearing capacity due to earthquakes pose a great threat to people’s lives and s…
View article: The influence of meaning in life on smartphone addiction among nursing undergraduates: the mediating roles of professional identity and achievement motivation
The influence of meaning in life on smartphone addiction among nursing undergraduates: the mediating roles of professional identity and achievement motivation Open
This study highlights the critical role of meaning in life in reducing smartphone addiction among nursing students. Professional identity and achievement motivation were identified as key mediating mechanisms. These findings provide valuab…
View article: Abdominal obesity and frailty progression in population across different Cardiovascular-Kidney-Metabolic syndrome stages: a nationwide longitudinal study
Abdominal obesity and frailty progression in population across different Cardiovascular-Kidney-Metabolic syndrome stages: a nationwide longitudinal study Open
Abdominal obesity, indicated by BRI, is a strong predictor of frailty progression, particularly in early CKM stages. High cumulative BRI, along with advanced CKM progression and persistent advanced CKM stages, further increases frailty ris…
View article: Phenome-wide associations of polygenic scores for schizophrenia and major depression in 100,000 Chinese adults
Phenome-wide associations of polygenic scores for schizophrenia and major depression in 100,000 Chinese adults Open
China faces significant mental health challenges, with unique associations between mental disorders and other traits observed in its population. Based on summary statistics in East Asian (EAS) and European (EUR) ancestries, we tested assoc…
View article: Intraoperative protective ventilation with or without periodic lung recruitment manoeuvres on pulmonary complications after major abdominal surgery (REMAIN-1): protocol for a randomised controlled trial
Intraoperative protective ventilation with or without periodic lung recruitment manoeuvres on pulmonary complications after major abdominal surgery (REMAIN-1): protocol for a randomised controlled trial Open
Introduction Postoperative pulmonary complications (PPCs) are frequent after abdominal surgery and significantly affect postoperative outcomes. Intraoperative protective ventilation (IPV) has been demonstrated to mitigate PPCs. However, th…
View article: Growth performance, intestinal health, and non-specific immunity were significantly affected by feeding different compound lactic acid bacteria supplementation in sea urchin (Strongylocentrotus intermedius)
Growth performance, intestinal health, and non-specific immunity were significantly affected by feeding different compound lactic acid bacteria supplementation in sea urchin (Strongylocentrotus intermedius) Open
A 50-day feeding trial was conducted to evaluate the effects of dietary supplementation with different levels of compound lactic acid bacteria on the growth performance, antioxidant capacity, intestinal microbiota composition, and immunity…
View article: Effects of Clostridium Butyricum on Intestinal Morphology, Serum Profiles, and Gut Microbiota in Weaned Piglets
Effects of Clostridium Butyricum on Intestinal Morphology, Serum Profiles, and Gut Microbiota in Weaned Piglets Open
View article: Graphics and Data Visualisation
Graphics and Data Visualisation Open
Understand the importance of data visualisation in communicating complex information effectively. Create various types of 2D and 3D plots using MATLAB functions such as , , , , , and . Visualise bfdata distributions using plots like histog…
View article: MULGONET: An interpretable neural network framework to integrate multi-omics data for cancer recurrence prediction and biomarker discovery
MULGONET: An interpretable neural network framework to integrate multi-omics data for cancer recurrence prediction and biomarker discovery Open
View article: Suzuki Segregation of Alloying Elements at Stacking Faults In Ag-Based Alloys
Suzuki Segregation of Alloying Elements at Stacking Faults In Ag-Based Alloys Open
View article: GA-S3: Comprehensive Social Network Simulation with Group Agents
GA-S3: Comprehensive Social Network Simulation with Group Agents Open
View article: Suzuki Segregation of Alloying Elements at Stacking Faults in Ag-Based Alloys
Suzuki Segregation of Alloying Elements at Stacking Faults in Ag-Based Alloys Open
View article: The Potential Relationship between GREM1 and Chronic Obstructive Pulmonary Disease
The Potential Relationship between GREM1 and Chronic Obstructive Pulmonary Disease Open
GREM1 has been confirmed to be involved in the mechanisms of fibrosis, tumors, and cardiovascular diseases. This article aims to discuss the potential relationship between GREM1 and Chronic Obstructive Pulmonary Disease (COPD), with mechan…
View article: Multi-Omics Analysis Reveals the Role of Tire Particles in the Mechanism of Neurodegeneration
Multi-Omics Analysis Reveals the Role of Tire Particles in the Mechanism of Neurodegeneration Open