Yiqun Hu
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View article: Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis
Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis Open
Trained immunity involves the reprogramming of innate immune cells after an initial exposure, resulting in heightened inflammatory responses to subsequent stimuli and enhanced bactericidal capacity during infection. However, this proinflam…
View article: Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis
Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis Open
Trained immunity involves the reprogramming of innate immune cells after an initial exposure, resulting in heightened inflammatory responses to subsequent stimuli and enhanced bactericidal capacity during infection. However, this proinflam…
View article: Author response: Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis
Author response: Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis Open
View article: The Casual Associations Between Brain Functional Networks and Fibromyalgia: A Large-Scale Genetic Correlation and Mendelian Randomization Study
The Casual Associations Between Brain Functional Networks and Fibromyalgia: A Large-Scale Genetic Correlation and Mendelian Randomization Study Open
While the central mechanisms of fibromyalgia have gained attention, the causal effects between brain networks and fibromyalgia remain unclear. Two-sample Mendelian randomization and Linkage Disequilibrium Score Regression were performed to…
View article: DSMentor: Enhancing Data Science Agents with Curriculum Learning and Online Knowledge Accumulation
DSMentor: Enhancing Data Science Agents with Curriculum Learning and Online Knowledge Accumulation Open
Large language model (LLM) agents have shown promising performance in generating code for solving complex data science problems. Recent studies primarily focus on enhancing in-context learning through improved search, sampling, and plannin…
View article: Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis
Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis Open
Trained immunity involves the reprogramming of innate immune cells after an initial exposure, resulting in heightened inflammatory responses to subsequent stimuli and enhanced bactericidal capacity during infection. However, this proinflam…
View article: A modified variable flip angle release device for endoscopic titanium clips
A modified variable flip angle release device for endoscopic titanium clips Open
View article: LCN2 deficiency mitigates the neuroinflammatory damage following acute glaucoma
LCN2 deficiency mitigates the neuroinflammatory damage following acute glaucoma Open
Rationale: Acute high intraocular pressure (IOP) induces retinal ischemia/reperfusion (RI/R) that further initiates neuroinflammatory responses. This event can cause retinal tissue damage and neuronal death, ultimately resulting in …
View article: CoddLLM: Empowering Large Language Models for Data Analytics
CoddLLM: Empowering Large Language Models for Data Analytics Open
Large Language Models (LLMs) have the potential to revolutionize data analytics by simplifying tasks such as data discovery and SQL query synthesis through natural language interactions. This work serves as a pivotal first step toward the …
View article: α-Methyl-Tryptophan Inhibits SLC6A14 Expression and Exhibits Immunomodulatory Effects in Crohn’s Disease
α-Methyl-Tryptophan Inhibits SLC6A14 Expression and Exhibits Immunomodulatory Effects in Crohn’s Disease Open
Our findings suggest that SLC6A14 could serve as a potential diagnostic biomarker and therapeutic target for CD. Furthermore, α-MT offers a novel approach for the clinical diagnosis and treatment of CD by targeting SLC6A14 for therapeutic …
View article: PRACTIQ: A Practical Conversational Text-to-SQL dataset with Ambiguous and Unanswerable Queries
PRACTIQ: A Practical Conversational Text-to-SQL dataset with Ambiguous and Unanswerable Queries Open
View article: Artificial intelligence models assisting physicians in quantifying pancreatic necrosis in acute pancreatitis
Artificial intelligence models assisting physicians in quantifying pancreatic necrosis in acute pancreatitis Open
Our proposed model could improve the effectiveness of clinicians in diagnosing pancreatic necrosis volume ratios in clinical settings.
View article: PRACTIQ: A Practical Conversational Text-to-SQL dataset with Ambiguous and Unanswerable Queries
PRACTIQ: A Practical Conversational Text-to-SQL dataset with Ambiguous and Unanswerable Queries Open
Previous text-to-SQL datasets and systems have primarily focused on user questions with clear intentions that can be answered. However, real user questions can often be ambiguous with multiple interpretations or unanswerable due to a lack …
View article: Physical activity combined with tea consumption could further reduce all-cause and cancer-specific mortality
Physical activity combined with tea consumption could further reduce all-cause and cancer-specific mortality Open
View article: Physical Activity Combined with Tea Consumption could further Reduce All-cause Mortality: Results from the US National Health and Nutrition Examination Survey, 2009-2018
Physical Activity Combined with Tea Consumption could further Reduce All-cause Mortality: Results from the US National Health and Nutrition Examination Survey, 2009-2018 Open
The study aimed to comprehensively assess the separate and combined effects of physical activity (PA) and tea consumption on all-cause mortality among 21,350 participants from The National Health and Nutrition Examination Survey (NHANES) b…
View article: The Diagnostic Role of Artificial Intelligence-Assisted Physicians in the Volume of Pancreatic Necrosis in Acute Pancreatitis
The Diagnostic Role of Artificial Intelligence-Assisted Physicians in the Volume of Pancreatic Necrosis in Acute Pancreatitis Open
View article: A Novel Diagnostic Model of Biomarkers in the Washing Fluid Obtained by Eus-Fna in Pancreatic Cancer
A Novel Diagnostic Model of Biomarkers in the Washing Fluid Obtained by Eus-Fna in Pancreatic Cancer Open
View article: Learning Mixed Multinomial Logits with Provable Guarantees and its Applications in Multi-product Pricing
Learning Mixed Multinomial Logits with Provable Guarantees and its Applications in Multi-product Pricing Open
View article: Effectiveness comparison between ustekinumab and infliximab for Crohn’s disease complicated with intestinal stenosis: a multicenter real-world study
Effectiveness comparison between ustekinumab and infliximab for Crohn’s disease complicated with intestinal stenosis: a multicenter real-world study Open
Background: The efficacy of ustekinumab (UST) and infliximab (IFX) in Crohn’s disease (CD) patients with intestinal stenosis remains uncertain. Objective: This study aims to compare the efficacy of UST and IFX in the treatment of CD patien…
View article: Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC
Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC Open
View article: Trends and projections of inflammatory bowel disease at the global, regional and national levels, 1990–2050: a bayesian age-period-cohort modeling study
Trends and projections of inflammatory bowel disease at the global, regional and national levels, 1990–2050: a bayesian age-period-cohort modeling study Open
View article: Real-time Sequence Images Registration based on Fast Least Squares Feature Point Tracking
Real-time Sequence Images Registration based on Fast Least Squares Feature Point Tracking Open
This study addresses the issues of diminished precision and sluggish computational pace observed in current sequence image registration algorithms. A sequence image registration algorithm based on adaptive feature point selection (AFPS) an…
View article: A deep learning method for foot-type classification using plantar pressure images
A deep learning method for foot-type classification using plantar pressure images Open
Background: Flat foot deformity is a prevalent and challenging condition often leading to various clinical complications. Accurate identification of abnormal foot types is essential for appropriate interventions. Method: A dataset consisti…
View article: Trends and projections of inflammatory bowel disease at the global and national levels, 1990–2050: A bayesian age-period-cohort modeling study
Trends and projections of inflammatory bowel disease at the global and national levels, 1990–2050: A bayesian age-period-cohort modeling study Open
Background: Inflammatory bowel disease (IBD) is a global health concern with varying levels and trends across countries and regions. Understanding these differences is crucial for effective prevention and treatment strategies. Methods: Usi…
View article: UNITE: A Unified Benchmark for Text-to-SQL Evaluation
UNITE: A Unified Benchmark for Text-to-SQL Evaluation Open
A practical text-to-SQL system should generalize well on a wide variety of natural language questions, unseen database schemas, and novel SQL query structures. To comprehensively evaluate text-to-SQL systems, we introduce a UNIfied benchma…
View article: Identification of calcium and integrin-binding protein 1 as a reprogrammed glucose metabolism mediator to restrict immune cell infiltration in the stromal compartment of pancreatic ductal adenocarcinoma
Identification of calcium and integrin-binding protein 1 as a reprogrammed glucose metabolism mediator to restrict immune cell infiltration in the stromal compartment of pancreatic ductal adenocarcinoma Open
An increasing body of evidence has suggested that reprogrammed metabolism plays a critical role in the progression of pancreatic ductal adenocarcinoma (PDAC) by affecting the tumor and stromal cellular components in the tumor microenvironm…
View article: The relationship between learning style and critical thinking based on learning modes
The relationship between learning style and critical thinking based on learning modes Open
Objective: This study is dedicated to uncovering the relationship between critical thinking (CT) and learning styles and the level of each learning mode, as a way of proposing a predictive model of CT that relies on the learning mode. Meth…
View article: PD-1+CD8+ T Cells Proximal to PD-L1+CD68+ Macrophages Are Associated with Poor Prognosis in Pancreatic Ductal Adenocarcinoma Patients
PD-1+CD8+ T Cells Proximal to PD-L1+CD68+ Macrophages Are Associated with Poor Prognosis in Pancreatic Ductal Adenocarcinoma Patients Open
Immune complexity status in the TME has been linked to clinical outcomes in pancreatic ductal adenocarcinoma (PDAC) patients. TME assessments with current cell marker and cell density-based analyses do not identify the original phenotypes …
View article: P321 Increased modified DUBLIN scores are associated with serious ulcerative colitis and treatment failure
P321 Increased modified DUBLIN scores are associated with serious ulcerative colitis and treatment failure Open
Background Grading of endoscopic lesions is important for determining the severity of ulcerative colitis and developing treatment strategies, but the commonly used methods are not sufficient.This study aimed to investigate whether new endo…
View article: Specific fungi associated with response to capsulized fecal microbiota transplantation in patients with active ulcerative colitis
Specific fungi associated with response to capsulized fecal microbiota transplantation in patients with active ulcerative colitis Open
Objective Fecal microbiota transplantation (FMT) is a novel microbial treatment for patients with ulcerative colitis (UC). In this study, we performed a clinical trial of capsulized FMT in UC patients to determine the association between t…