Yangyang Qu
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View article: Life-Threatening Ventricular Arrhythmia Identification Based on Multiple Complex Networks
Life-Threatening Ventricular Arrhythmia Identification Based on Multiple Complex Networks Open
Ventricular arrhythmias (VAs) are critical cardiovascular diseases that require rapid and accurate detection. Conventional approaches relying on multi-lead ECG or deep learning models have limitations in computational cost, interpretabilit…
View article: ADAM8 deficiency in macrophages promotes cardiac repair after myocardial infarction via ANXA2-mTOR-autophagy pathway
ADAM8 deficiency in macrophages promotes cardiac repair after myocardial infarction via ANXA2-mTOR-autophagy pathway Open
ADAM8 was increased in cardiac macrophages after AMI. The ADAM8-ANXA2-mTOR-autophagy axis in macrophages is responsible for regulating angiogenesis and inflammation following MI. Thus, ADAM8 may be a new target in MI treatment.
View article: ADAM8 deficiency in macrophages promotes angiogenesis to antagonize post-myocardial infarction cardiac injury
ADAM8 deficiency in macrophages promotes angiogenesis to antagonize post-myocardial infarction cardiac injury Open
Background A disintegrin and metallopeptidase domain 8 (ADAM8) may be closely related to the progress of cardiovascular diseases. ADAM8 was first found in macrophages from mice, and ADAM family is closely related to the secretion function …
View article: Isolation and identification of a pathogenic strain of Bacillus cereus from bovine and establishment of a rapid detection method for RPA-LF
Isolation and identification of a pathogenic strain of Bacillus cereus from bovine and establishment of a rapid detection method for RPA-LF Open
In order to identify the cause of death of a cattle that suddenly died on a cattle farm in Tongliao City, Inner Mongolia Autonomous Region, we isolated a strain of bacteria from the spleen and identified the pathogen. The study demonstrate…
View article: Very high HDL-C (high-density lipoprotein cholesterol) is associated with increased cardiovascular risk in patients with NSTEMI (non-ST-segment elevation myocardial infarction) undergoing PCI (percutaneous coronary intervention)
Very high HDL-C (high-density lipoprotein cholesterol) is associated with increased cardiovascular risk in patients with NSTEMI (non-ST-segment elevation myocardial infarction) undergoing PCI (percutaneous coronary intervention) Open
Background Studies in populations with or without cardiovascular disease have shown that very high HDL-C levels are associated with an increased risk of cardiovascular events. However, the exact relationship between HDL-C levels and long-t…
View article: [Prediction of 1p/19q codeletion status in diffuse lower-grade glioma using multimodal MRI radiomics].
[Prediction of 1p/19q codeletion status in diffuse lower-grade glioma using multimodal MRI radiomics]. Open
Multiparametric MRI radiomics models show good performance for noninvasive prediction of 1p/19q codeletion status in patients with in diffuse lower-grade glioma.
View article: Upregulation of Biomarker Limd1 Was Correlated with Immune Infiltration in Doxorubicin-Related Cardiotoxicity
Upregulation of Biomarker Limd1 Was Correlated with Immune Infiltration in Doxorubicin-Related Cardiotoxicity Open
Doxorubicin is one of the most common antitumor drugs. However, cardiotoxicity’s side effect limits its clinical applicability. In the present study, Gene Expression Omnibus (GEO) datasets were applied to reanalyze differentially expressed…
View article: Age-Related Utilization of Thrombus Aspiration in Patients With ST-Segment Elevation Myocardial Infarction: Findings From the Improving Care for Cardiovascular Disease in China Project
Age-Related Utilization of Thrombus Aspiration in Patients With ST-Segment Elevation Myocardial Infarction: Findings From the Improving Care for Cardiovascular Disease in China Project Open
Background There are some controversies on the utilization and benefits of thrombus aspiration in patients with ST-segment elevation myocardial infarction (STEMI). However, a few studies investigated this issue and the age-associated effec…
View article: Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium
Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium Open
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can target cardiomyocytes (CMs) to directly invade the heart resulting in high mortality. This study aims to explore the biological characteristics of SARS-CoV-2 infected myo…
View article: Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium
Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium Open
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can target cardiomyocytes (CMs) to directly invade the heart resulting in high mortality. This study aims to explore the biological characteristics of SARS-CoV-2 infected myo…
View article: Quantifying Patient-Specific in vivo Coronary Plaque Material Properties for Accurate Stress/Strain Calculations: An IVUS-Based Multi-Patient Study
Quantifying Patient-Specific in vivo Coronary Plaque Material Properties for Accurate Stress/Strain Calculations: An IVUS-Based Multi-Patient Study Open
Introduction: Mechanical forces are closely associated with plaque progression and rupture. Precise quantifications of biomechanical conditions using in vivo image-based computational models depend heavily on the accurate estimation of pat…
View article: Optical coherence tomography-defined vulnerable plaque characteristics in relation to functional severity of coronary stenoses stratified by quantitative flow ratio
Optical coherence tomography-defined vulnerable plaque characteristics in relation to functional severity of coronary stenoses stratified by quantitative flow ratio Open
Background The functional severity and morphological features of epicardial lesions are both related to plaque vulnerability and adverse coronary events. However, their relationship remains controversial, especially in patients with non-ST…
View article: The Neutrophil-to-Lymphocyte Ratio Is an Important Indicator Predicting In-Hospital Death in AMI Patients
The Neutrophil-to-Lymphocyte Ratio Is an Important Indicator Predicting In-Hospital Death in AMI Patients Open
Objective: To explore the role of neutrophil-to-lymphocyte ratio (NLR) in predicting the short-term prognosis of NSTEMI and STEMI. Methods: This study was a single-center, retrospective and observational study. 2618 patients including 1289…
View article: The Association Between Quantitative Flow Ratio and Intravascular Imaging-defined Vulnerable Plaque Characteristics in Patients With Stable Angina and Non-ST-segment Elevation Acute Coronary Syndrome
The Association Between Quantitative Flow Ratio and Intravascular Imaging-defined Vulnerable Plaque Characteristics in Patients With Stable Angina and Non-ST-segment Elevation Acute Coronary Syndrome Open
Background: This study aimed to examine whether quantitative flow ratio (QFR), an angiography-based computation of fractional flow reserve, was associated with intravascular imaging-defined vulnerable plaque features, such as thin cap fibr…
View article: Quantitative Assessment of Left and Right Atrial Strains Using Cardiovascular Magnetic Resonance Based Tissue Tracking
Quantitative Assessment of Left and Right Atrial Strains Using Cardiovascular Magnetic Resonance Based Tissue Tracking Open
Background: Left and right atrium (LA and RA) exert an essential and dynamic role in ventricular filling and hence affect heart performance. Strain quantification has been reported as a novel parameter to assess function. However, the asse…
View article: Peer Review #1 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.1)"
Peer Review #1 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.1)" Open
Background.Acute myocardial infarction (AMI) is one of the fatal cardiac emergencies.The detection of Triggering receptor expressed on myeloid cells 1 (TREM1), a cell surface immunoglobulin that amplifies pro-inflammatory responses, screen…
View article: Peer Review #1 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.2)"
Peer Review #1 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.2)" Open
Background.Acute myocardial infarction (AMI) is one of the fatal cardiac emergencies.The detection of Triggering receptor expressed on myeloid cells 1 (TREM1), a cell surface immunoglobulin that amplifies pro-inflammatory responses, screen…
View article: Peer Review #2 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.1)"
Peer Review #2 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.1)" Open
Background.Acute myocardial infarction (AMI) is one of the fatal cardiac emergencies.The detection of Triggering receptor expressed on myeloid cells 1 (TREM1), a cell surface immunoglobulin that amplifies pro-inflammatory responses, screen…
View article: Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study
Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study Open
Background Acute myocardial infarction (AMI) is one of the fatal cardiac emergencies. The detection of triggering receptor expressed on myeloid cells 1 (TREM1), a cell surface immunoglobulin that amplifies pro-inflammatory responses, scree…
View article: Clinical prediction models of fractional flow reserve: an exploration of the current evidence and appraisal of model performance
Clinical prediction models of fractional flow reserve: an exploration of the current evidence and appraisal of model performance Open
Almost half of the existing FFR CPMs had been externally validated. Due to their good discrimination abilities, these FFR CPMs are useful tools that could reduce the need for invasive hemodynamic measurements. Future research that adheres …
View article: Left ventricular myocardial strain quantification with two- and three-dimensional cardiovascular magnetic resonance based tissue tracking
Left ventricular myocardial strain quantification with two- and three-dimensional cardiovascular magnetic resonance based tissue tracking Open
CMR-TT is a feasible and reproducible technique for assessing LV myocardial deformation, especially at the global level. The establishment of specific reference values of LV global and segmental systolic strains and the investigation of di…
View article: Quantification of Biventricular Myocardial Strain Using CMR Feature Tracking: Reproducibility in Small Animals
Quantification of Biventricular Myocardial Strain Using CMR Feature Tracking: Reproducibility in Small Animals Open
Myocardial strain is a well‐validated parameter for evaluating myocardial contraction. Cardiovascular magnetic resonance myocardial feature tracking (CMR‐FT) is a novel method for the quantitative measurements of myocardial strain from rou…
View article: N-methyladenosine methyltransferase plays a role in hypoxic preconditioning partially through the interaction with lncRNA H19
N-methyladenosine methyltransferase plays a role in hypoxic preconditioning partially through the interaction with lncRNA H19 Open
N6-methyladenosine (m6A), a methylation in the N6 position of adenosine especially in the mRNA, exerts diverse physiological and pathological functions. However, the precise role of m6A methylation in hypoxic preconditioning (HPC) is still…
View article: Triglyceride to high-density lipoprotein cholesterol ratio as a risk factor of repeat revascularization among patients with acute coronary syndrome after first-time percutaneous coronary intervention
Triglyceride to high-density lipoprotein cholesterol ratio as a risk factor of repeat revascularization among patients with acute coronary syndrome after first-time percutaneous coronary intervention Open
The TG/HDL-C ratio and Gensini score could serve as risk factors for repeat revascularization in ACS patients after a first-time successful PCI.
View article: Outcomes after percutaneous coronary intervention and comparison among scoring systems in predicting procedural success in elderly patients (≥ 75 years) with chronic total occlusion
Outcomes after percutaneous coronary intervention and comparison among scoring systems in predicting procedural success in elderly patients (≥ 75 years) with chronic total occlusion Open
Despite the lower procedural success rate, percutaneous coronary intervention in elderly patients with CTO is feasible and safe. J-CTO, PROGRESS, ORA, and CL scoring systems have moderate discriminatory capacity.
View article: Age- and gender-related reference values of biventricular strains measured by cardiovascular magnetic resonance based tissue tracking
Age- and gender-related reference values of biventricular strains measured by cardiovascular magnetic resonance based tissue tracking Open
Background: Cardiovascular magnetic resonance based tissue tracking (CMR-TT) was reported to provide detailed insight into bi-ventricular contractile function and deformation with two- and/or three-dimensional (2/3D) algorithms. This study…