Yiwei Zhao
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View article: Shoulder balance in Lenke type 2 adolescent idiopathic scoliosis: the role of upper instrumented vertebrae selection and risk factor analysis
Shoulder balance in Lenke type 2 adolescent idiopathic scoliosis: the role of upper instrumented vertebrae selection and risk factor analysis Open
View article: Risk Factors for Neurological Complications in Severe Spinal Deformity Surgery
Risk Factors for Neurological Complications in Severe Spinal Deformity Surgery Open
Objective Severe spinal deformities, including scoliosis and kyphosis, present significant challenges in corrective surgery due to the elevated risk of neurological complications. The identification of preoperative risk factors is of param…
View article: Long-term growth and risk factors for crankshaft phenomenon following posterior hemivertebra resection with mono-segment fusion in congenital early-onset scoliosis
Long-term growth and risk factors for crankshaft phenomenon following posterior hemivertebra resection with mono-segment fusion in congenital early-onset scoliosis Open
View article: Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation
Mechanical tension-induced Dalrd3 elevation enhances osteogenic differentiation of bone suture stem cells by upregulating Id3 translation Open
These findings reveal a translational regulatory mechanism in SuSCs activated by mechanical tension and underscore the pivotal role of Dalrd3 in suture remodeling and bone formation. The insights provided by this study have the potential t…
View article: Long-term results of single-stage posterior hemivertebra resection and short segment fusion using pedicle screws fixation in thoracolumbar congenital early-onset scoliosis: an 8.97-year average follow-up study
Long-term results of single-stage posterior hemivertebra resection and short segment fusion using pedicle screws fixation in thoracolumbar congenital early-onset scoliosis: an 8.97-year average follow-up study Open
One-stage posterior hemivertebra resection and short segment fusion with pedicle screw fixation effectively correct TLCEOS long-term, offering significant improvements in patient appearance and satisfaction, with a manageable complication …
View article: Is It Enough to Stop Distal Fusion at <scp>L3</scp> in Mild to Moderate Lenke <scp>5C</scp> Adolescent Idiopathic Scoliosis Patients?
Is It Enough to Stop Distal Fusion at <span>L3</span> in Mild to Moderate Lenke <span>5C</span> Adolescent Idiopathic Scoliosis Patients? Open
Objective There has been no definitive conclusion on the selection of the lowest instrumented vertebra (LIV) in Lenke 5C adolescent idiopathic scoliosis (AIS) patients. The purpose of this study was to evaluate whether it is enough to stop…
View article: Classification of Emerging Scoliosis in Congenital Scoliosis After Hemivertebra Resection and Short Segmental Fusion
Classification of Emerging Scoliosis in Congenital Scoliosis After Hemivertebra Resection and Short Segmental Fusion Open
Objective Emerging scoliosis (ES) is a rare phenomenon after hemivertebra (HV) resection and short segmental fusion. Since the introduction of the ES, there have been rare in‐depth studies. The aim of the present study was to further analy…
View article: A Novel growth guidance system for early onset scoliosis: a preliminary in vitro study
A Novel growth guidance system for early onset scoliosis: a preliminary in vitro study Open
Purpose The purpose of the study was to describe a novel growth guidance system, which can avoid metal debris and reduce the sliding friction forces, and test the durability and glidability of the system by in vitro test. Method Two major …
View article: Lowest Instrumented Vertebra at L3 Versus L4 in Posterior Fusion for Moderate Lenke 5C Type Adolescent Idiopathic Scoliosis: A Case-Match Radiological Study
Lowest Instrumented Vertebra at L3 Versus L4 in Posterior Fusion for Moderate Lenke 5C Type Adolescent Idiopathic Scoliosis: A Case-Match Radiological Study Open
Objective: To compare the radiological outcomes in Lenke 5C type patients whose lowest instrumented vertebra (LIV) was L3 or L4 in a case-match study.Methods: We conducted a retrospective case-match study and included 82 patients in the st…
View article: Traditional Dual Growing Rods With 2 Different Apical Control Techniques in the Treatment of Early-Onset Scoliosis
Traditional Dual Growing Rods With 2 Different Apical Control Techniques in the Treatment of Early-Onset Scoliosis Open
Objective: Based on traditional dual growing rods (TDGR), apical control techniques (ACTs) were introduced as adjuvant procedures to improve deformity correction at the apex segment in the treatment of early-onset scoliosis (EOS). We aimed…
View article: The Causal Association Between Gestational Diabetes Mellitus and Arthritis: A Bidirectional Two-Sample Mendelian Randomization Analysis
The Causal Association Between Gestational Diabetes Mellitus and Arthritis: A Bidirectional Two-Sample Mendelian Randomization Analysis Open
Background The long-term complications of gestational diabetes mellitus (GDM) may be associated with the development of arthritis, particularly rheumatoid arthritis (RA) and osteoarthritis (OA). However, the possible relationship between t…
View article: Dynamic Ins2 gene activity defines β-cell maturity states
Dynamic Ins2 gene activity defines β-cell maturity states Open
Transcriptional and functional cellular specialization has been described for insulin-secreting β-cells of the endocrine pancreas. However, it is not clear whether β-cell heterogeneity is stable or reflects dynamic cellular states. We inve…
View article: Dynamic <i>Ins2</i> Gene Activity Defines β-Cell Maturity States
Dynamic <i>Ins2</i> Gene Activity Defines β-Cell Maturity States Open
Transcriptional and functional cellular specialization has been described for insulin-secreting β-cells of the endocrine pancreas. However, it is not clear whether β-cell heterogeneity is stable or reflects dynamic cellular states. We inve…
View article: Dynamic Ins2 gene activity defines β-cell maturity states
Dynamic Ins2 gene activity defines β-cell maturity states Open
Transcriptional and functional cellular specialization has been described for insulin-secreting β-cells of the endocrine pancreas. However, it is not clear whether β-cell heterogeneity is stable or reflects dynamic cellular states. We inve…
View article: Dynamic Ins2 gene activity defines β-cell maturity states
Dynamic Ins2 gene activity defines β-cell maturity states Open
Transcriptional and functional cellular specialization has been described for insulin-secreting β-cells of the endocrine pancreas. However, it is not clear whether β-cell heterogeneity is stable or reflects dynamic cellular states. We inve…
View article: The Verification of Differentially Expressed Genes Related to Feather Colour in Quail Embryos by RT-qPCR Based on RNA-seq
The Verification of Differentially Expressed Genes Related to Feather Colour in Quail Embryos by RT-qPCR Based on RNA-seq Open
Many differentially expressed genes associated with feather colour in quail embryos can be screened using RNA-seq technology. The aim of this study was to verify the accuracy of RNA-seq using RT-qPCR. The transcriptome of embryonic s…
View article: CCT2 enhances the proliferation and migration of head and neck squamous cell carcinoma via regulating cell cycle
CCT2 enhances the proliferation and migration of head and neck squamous cell carcinoma via regulating cell cycle Open
Recent therapeutic advances have improved the survival of head and neck squamous cell carcinoma (HNSCC) patients, but the prognosis of HNSCC remains dismal. Further understanding of the underlying mechanism of HNSCC progression is still an…
View article: A Novel Berberine–Glycyrrhizic Acid Complex Formulation Enhanced the Prevention Effect to Doxorubicin-Induced Cardiotoxicity by Pharmacokinetic Modulation of Berberine in Rats
A Novel Berberine–Glycyrrhizic Acid Complex Formulation Enhanced the Prevention Effect to Doxorubicin-Induced Cardiotoxicity by Pharmacokinetic Modulation of Berberine in Rats Open
Developing a new drug delivery system is one of the useful approaches to overcome the limited use of berberine (BBR) to enhance its absorption and bioavailability. We prepared a novel berberine–glycyrrhizic acid (BBR–GL) complex formulatio…
View article: Water-Sealed Blasting Control Measures of the Metro Station Undercrossing Existing Structures in Ultra-Close Distances: A Case Study
Water-Sealed Blasting Control Measures of the Metro Station Undercrossing Existing Structures in Ultra-Close Distances: A Case Study Open
Based on the project of People’s Hall Station of Qingdao Metro Line 4 in China, the method of water-sealed blasting construction for vibration damping is proposed, as the blasting vibration of adjacent structures (Qingdao Metro Line 3) doe…
View article: Adalimumab in Japanese patients with active ulcers of pyoderma gangrenosum: Final analysis of a <scp>52‐week</scp> phase 3 open‐label study
Adalimumab in Japanese patients with active ulcers of pyoderma gangrenosum: Final analysis of a <span>52‐week</span> phase 3 open‐label study Open
In this 52‐week, phase 3 open‐label study, efficacy and safety of adalimumab were evaluated in Japanese patients with active ulcers due to pyoderma gangrenosum (PG) during a 26‐week treatment period and another 26‐week extension period. Pa…
View article: Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics Open
View article: Additional file 2 of Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics
Additional file 2 of Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics Open
Additional file 2: Table S2. Genes differentially expressed between genotypes for each cell cluster.
View article: Surpassing Pt Hydrogen Production from {200} Facet-Riched Polyhedral Rh2p Nanoparticles by One-Step Synthesis
Surpassing Pt Hydrogen Production from {200} Facet-Riched Polyhedral Rh2p Nanoparticles by One-Step Synthesis Open
View article: Surpassing Pt Hydrogen Production from {200} Facet-Riched Polyhedral Rh2p Nanoparticles by One-Step Synthesis
Surpassing Pt Hydrogen Production from {200} Facet-Riched Polyhedral Rh2p Nanoparticles by One-Step Synthesis Open
View article: Long‐term safety of risankizumab from 17 clinical trials in patients with moderate‐to‐severe plaque psoriasis*
Long‐term safety of risankizumab from 17 clinical trials in patients with moderate‐to‐severe plaque psoriasis* Open
Risankizumab demonstrated a favourable safety profile over short- and long-term treatment in patients with moderate-to-severe psoriasis.
View article: Posterior Temporary C1-2 Pedicle Screws Fixation for the Treatment of Unstable C1-2 Complex Fractures: Minimum of 2-Year Follow-Up
Posterior Temporary C1-2 Pedicle Screws Fixation for the Treatment of Unstable C1-2 Complex Fractures: Minimum of 2-Year Follow-Up Open
Study Design: Retrospective. Objectives: To present rarely reported complex fractures of the upper cervical spine (C1-C2) and discuss the clinical results of the posterior temporary C1-2 pedicle screws fixation for C1-C2 stabilization. Met…
View article: Long‐term efficacy and safety of risankizumab for the treatment of moderate‐to‐severe plaque psoriasis: interim analysis of the LIMMitless open‐label extension trial beyond 3 years of follow‐up
Long‐term efficacy and safety of risankizumab for the treatment of moderate‐to‐severe plaque psoriasis: interim analysis of the LIMMitless open‐label extension trial beyond 3 years of follow‐up Open
Overall, long-term continuous RZB was well tolerated and showed high and durable efficacy over 172 weeks.
View article: An unusual injury mechanism of atlantoaxial dislocation: illustrative case
An unusual injury mechanism of atlantoaxial dislocation: illustrative case Open
BACKGROUND Atlantoaxial dislocation (AAD) is a rare and potentially life-threatening condition. Various underlying mechanisms of injury are described in the literature. Here, the authors report an unusual nontraumatic injury mechanism of A…
View article: Clinical Validity of 3 Different Grading Systems for Facet Joint Violation: A Retrospective Study and In-Depth Review
Clinical Validity of 3 Different Grading Systems for Facet Joint Violation: A Retrospective Study and In-Depth Review Open
Study Design: Retrospective. Objectives: To study the violation rate of 3 different types of facet joint violation (FJV) grading systems (Babu, Shah, and Park), and to evaluate the accuracy, reliability, and association with clinical outco…
View article: Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics Open
Hyperinsulinemia is independently associated with increased risk and mortality of pancreatic cancer. We recently reported that a ∼50% reduction in pancreatic intraepithelial neoplasia (PanIN) pre-cancerous lesions in mice could be achieved…