Yinglei Miao
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View article: Impact of dietary emulsifiers on the presence of adherent-invasive Escherichia coli in Crohn’s disease
Impact of dietary emulsifiers on the presence of adherent-invasive Escherichia coli in Crohn’s disease Open
Adherent-invasive Escherichia coli (AIEC) has been implicated in Crohn’s disease (CD) pathogenesis. We aimed to evaluate the impact of dietary factors on the presence of AIEC in patients with CD and to identify AIEC-associated mucosa…
View article: Fermented dairy products intake and stroke risk: analyses of NHANES 2007–2018 data
Fermented dairy products intake and stroke risk: analyses of NHANES 2007–2018 data Open
Background Stroke ranks among the main diseases resulting in death and disability, imposing a heavy burden on both the country and individuals. Healthy foods can effectively prevent the occurrence of stroke, and fermented dairy products ar…
View article: Discovery and Validation of Novel Biomarkers for Colorectal Neoplasia Detection via Plasma Metabolomics
Discovery and Validation of Novel Biomarkers for Colorectal Neoplasia Detection via Plasma Metabolomics Open
Metabolic disturbance plays a critical role in the initiation of colorectal cancer (CRC), yet the identification of metabolites that are useful for early detection of CRC and its precursor lesions remains elusive. We conducted an untargete…
View article: Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity Open
Chemoresistance is a main cause of colorectal cancer (CRC) treatment failure. We identified that Bacteroides fragilis is enriched in patients with CRC resistant to chemotherapy in two independent cohorts, and its abundance is associated wi…
View article: Heat shock transcription factor 2 reduces mitochondrial pathway apoptosis in intestinal epithelial cells by inhibiting the increase in mitochondrial membrane permeability in ulcerative colitis
Heat shock transcription factor 2 reduces mitochondrial pathway apoptosis in intestinal epithelial cells by inhibiting the increase in mitochondrial membrane permeability in ulcerative colitis Open
The destruction of intestinal mucosal mechanical barrier homeostasis caused by excessive apoptosis of intestinal epithelial cells (IECs) is an important reason for the occurrence and development of ulcerative colitis (UC). The increase in …
View article: Differences in Lung Cancer-related Clinical Practice and Basic Research Background between Japan and China: A Narrative Review
Differences in Lung Cancer-related Clinical Practice and Basic Research Background between Japan and China: A Narrative Review Open
With its increasing incidence, lung cancer has become one of the leading causes of cancer-related deaths worldwide, posing a great threat to the health and lives of patients. Due to varying economic and cultural backgrounds, there are sign…
View article: Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function
Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function Open
Numerous studies have confirmed that gut microbiota is a key driver in the occurrence and progression of inflammatory bowel disease (IBD). Based on the bacterial collection constructed in our previous studies, we founded that Bifidobacteri…
View article: Keratin 1 modulates intestinal barrier and immune response <i>via</i> kallikrein kinin system in ulcerative colitis
Keratin 1 modulates intestinal barrier and immune response <i>via</i> kallikrein kinin system in ulcerative colitis Open
BACKGROUND External factors in ulcerative colitis (UC) exacerbate colonic epithelial permeability and inflammatory responses. Keratin 1 (KRT1) is crucial in regulating these alterations, but its specific role in the progression of UC remai…
View article: Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3
Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3 Open
Ubiquitin-specific protease 25 (USP25), a member of the deubiquitination family, plays an important role in protein ubiquitination, degradation, inflammation, and immune regulation. However, the role and mechanism of USP25 in ulcerative co…
View article: Long Non‐Coding <scp>RNA LINC01116</scp> Promotes the Proliferation of Lung Adenocarcinoma by Targeting <scp>miR</scp>‐9‐5p/<scp>CCNE1</scp> Axis
Long Non‐Coding <span>RNA LINC01116</span> Promotes the Proliferation of Lung Adenocarcinoma by Targeting <span>miR</span>‐9‐5p/<span>CCNE1</span> Axis Open
Long non‐coding RNA (lncRNA) LINC01116 is crucial in promoting cell proliferation, invasion and migration in solid tumours, including lung adenocarcinoma (LUAD). LINC01116 acts as a competing endogenous RNAs (ceRNA) that binds competitivel…
View article: Changes in amino acid concentrations and the gut microbiota composition are implicated in the mucosal healing of ulcerative colitis and can be used as noninvasive diagnostic biomarkers
Changes in amino acid concentrations and the gut microbiota composition are implicated in the mucosal healing of ulcerative colitis and can be used as noninvasive diagnostic biomarkers Open
Altered concentrations of amino acids and their associations with the gut microbiota are implicated in the mucosal healing of UC patients and can serve as noninvasive diagnostic biomarkers.
View article: Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011–2018 data
Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011–2018 data Open
Background Epidemiological surveys show that there is a significant gender difference in the incidence of stroke, with females having a noticeably higher rate than males. Accordingly, it is crucial to seek preventive measures for stroke sp…
View article: Pericentriolar material 1 promotes intestinal inflammation in ulcerative colitis by activating <scp>NLRP3</scp> /gasdermin D‐mediated macrophage pyroptosis
Pericentriolar material 1 promotes intestinal inflammation in ulcerative colitis by activating <span>NLRP3</span> /gasdermin D‐mediated macrophage pyroptosis Open
Excessive proinflammatory cytokine release induced by pyroptosis plays a vital role in intestinal mucosal inflammation in ulcerative colitis (UC). Several pyroptosis‐related factors are regulated by the centrosome. Pericentriolar material …
View article: Natural course of ulcerative colitis in China: Differences from the West?
Natural course of ulcerative colitis in China: Differences from the West? Open
Background and Aims Whether the natural course of ulcerative colitis (UC) in mainland China is similar or different from that in Western countries is unknown, and data on it is limited. We aimed to provide a comprehensive description of th…
View article: Independent and Joint Associations of Socioeconomic Status and Lifestyle behaviors with Cognitive Impairment among Elderly Chinese Population
Independent and Joint Associations of Socioeconomic Status and Lifestyle behaviors with Cognitive Impairment among Elderly Chinese Population Open
Cognitive impairment has socioeconomic disparities among the elderly Chinese population. A healthy lifestyle may attenuate the impact of socioeconomic inequality on cognitive impairment, emphasizing the important role of LBs modification i…
View article: Gut mycobiome alterations in obesity in geographically different regions
Gut mycobiome alterations in obesity in geographically different regions Open
The gut fungi play important roles in human health and are involved in energy metabolism. This study aimed to examine gut mycobiome composition in obese subjects in two geographically different regions in China and to identify specific gut…
View article: The gut ileal mucosal virome is disturbed in patients with Crohn’s disease and exacerbates intestinal inflammation in mice
The gut ileal mucosal virome is disturbed in patients with Crohn’s disease and exacerbates intestinal inflammation in mice Open
Gut bacteriome dysbiosis is known to be implicated in the pathogenesis of inflammatory bowel disease (IBD). Crohn’s disease (CD) is an IBD subtype with extensive mucosal inflammation, yet the mucosal virome, an empirical modulator of the b…
View article: The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic Stages
The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic Stages Open
During the 20th century, inflammatory bowel disease (IBD) was considered a disease of early-industrialized regions in North America, Europe, and Oceania. At the turn of the 21st century, incidence of IBD increased in newly-industrialized a…
View article: Heme Oxygenase-1 Alleviates Ischemia-Reperfusion Injury by Inhibiting Hepatocyte Pyroptosis after Liver Transplantation in Rats
Heme Oxygenase-1 Alleviates Ischemia-Reperfusion Injury by Inhibiting Hepatocyte Pyroptosis after Liver Transplantation in Rats Open
Objective: Heme oxygenase-1 (HO-1) is a protein involved in the inflammatory response following ischemia-reperfusion injury (IRI). Evidence suggests that pyroptosis plays an important role in IRI. However, the underlying mechanism between …
View article: Immunological function and prognostic value of lymphoid-specific helicase in liver hepatocellular carcinoma
Immunological function and prognostic value of lymphoid-specific helicase in liver hepatocellular carcinoma Open
BACKGROUND: Lymphoid-specific helicase (HELLS), a SNF2-like chromatin-remodeling enzyme, plays a key role in tumor progression via its DNA methylation function. However, the effects of HELLS on immune infiltration and prognosis in liver he…
View article: Editorial: Microbiome in IBD: From Composition to Therapy, Volume II
Editorial: Microbiome in IBD: From Composition to Therapy, Volume II Open
EDITORIAL article Front. Pharmacol., 05 April 2023Sec. Gastrointestinal and Hepatic Pharmacology Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1184269
View article: Constructing a prediction model of inflammatory bowel disease recurrence based on factors affecting the quality of life
Constructing a prediction model of inflammatory bowel disease recurrence based on factors affecting the quality of life Open
Aim This study aimed to determine the factors affecting the quality of life of patients with inflammatory bowel disease (IBD) and to construct a disease recurrence prediction model based on these influencing factors. Methods A prospective,…
View article: Alterations in metabolome and microbiome signatures provide clues to the role of antimicrobial peptide KT2 in ulcerative colitis
Alterations in metabolome and microbiome signatures provide clues to the role of antimicrobial peptide KT2 in ulcerative colitis Open
Introduction Ulcerative colitis (UC) is an inflammatory disease of the intestinal tract with unknown etiology. Both genetic and environmental factors are involved in the occurrence and development of UC. Understanding changes in the microb…