Explanipedia

Correlation risk analysis of serum Ang1-7 levels, ALBI scores and cardiac function in patients with heart failure Open

Jianhua Shen, Junyang Chen, Yiyong Liu, Mingchuan Zhang · 2025

Objective: To explore the relationships between the serum angiotensin 1‒7 (Ang1‒7) and albumin‒bilirubin (ALBI) scores and cardiac function and short-term prognosis in patients with acute decompensated heart failure (ADHF). Methods: A tota…

The GPCR NMUR-1 mediates neural regulation of energy homeostasis in response to pathogen infection Open

Phillip Wibisono, Yiyong Liu, Kenneth P. Roberts, Dodge L. Baluya, Jingru Sun · 2025

A key challenge in immunology is understanding how the innate immune system achieves specificity against diverse pathogens. Our previous work in Caenorhabditis elegans identified NMUR-1, a neuronal G protein-coupled receptor homologous to …

The GCN-2/eIF-2α/ATF-4 signaling pathway is involved in C. elegans defense against Salmonella enterica infection Open

Shawndra Wibisono, Phillip Wibisono, Yiyong Liu, Jingru Sun · 2025

In response to external or endogenous stress, eukaryotic cells can activate a common adaptive pathway called the integrated stress response (ISR). The ISR reduces global protein translation but upregulates the expression of stress response…

DATA MODEL OF COMPONENTS OF COMPLEX TECHNICAL SYSTEMS BASED ON SEMANTIC NETWORKS Open

Pavlo Pustovoitov, Volodymyr Kompaniiets, Yiyong Liu, Галіна Сокол, Medhat Awadalla · 2025

The article addresses the problem of ontological modeling of technical objects characterized by complex multi-level structure, diverse functional properties, and significant volume of accompanying documentation. A method for representing t…

Complete genome sequence of frog virus 3 isolated from a wild Eastern box turtle ( Terrapene carolina carolina ) in New Jersey, USA Open

Amany Hassan, Joseph M. Groff, Yiyong Liu, J. M. Reno, Kathleen M. McMenamin-Snekvik , et al. · 2025

The complete genome sequence of a frog virus 3 (FV3) isolate from a wild Eastern box turtle was determined. Comparative genomic analyses confirmed the close genetic relationship of this virus to previous FV3 isolates from reptiles includin…

The Caenorhabditis elegans neuronal GPCR OCTR-1 modulates longevity responses to both warm and cold temperatures Open

Shawndra Wibisono, Phillip Wibisono, Chia-Hui Chen, Jingru Sun, Yiyong Liu · 2025

Neuronal GPCR NMUR-1 regulates energy homeostasis in response to pathogen infection Open

Phillip Wibisono, Yiyong Liu, Kenneth P. Roberts, Dodge L. Baluya, Jingru Sun · 2024

SUMMARY A key question in current immunology is how the innate immune system generates high levels of specificity. Our previous study in Caenorhabditis elegans revealed that NMUR-1, a neuronal G protein-coupled receptor homologous to mamma…

Efficient Data-Free Model Stealing with Label Diversity Open

Yiyong Liu, Rui Wen, Michael Backes, Yang Zhang · 2024

Machine learning as a Service (MLaaS) allows users to query the machine learning model in an API manner, which provides an opportunity for users to enjoy the benefits brought by the high-performance model trained on valuable data. This int…

Transferable Availability Poisoning Attacks Open

Yiyong Liu, Michael Backes, Zhang Xiao · 2023

We consider availability data poisoning attacks, where an adversary aims to degrade the overall test accuracy of a machine learning model by crafting small perturbations to its training data. Existing poisoning strategies can achieve the a…

Integrated miRNA and mRNA Transcriptome Analysis Reveals Eggplant’s (Solanum melongena L.) Responses to Waterlogging Stress Open

Zheng Jiang, Xia Xin, Yiyong Liu, Jie He, Xu Yang · 2023

Waterlogging stress poses a significant threat to eggplants (Solanum melongena L.), causing root oxygen deficiency and subsequent plant damage. This study aims to explore the morphological changes and chlorophyll and lignin indicators of e…

The longevity response to warm temperature is neurally controlled via the regulation of collagen genes Open

Sankara Naynar Palani, Durai Sellegounder, Phillip Wibisono, Yiyong Liu · 2023

Studies in diverse species have associated higher temperatures with shorter lifespan and lower temperatures with longer lifespan. These inverse effects of temperature on longevity are traditionally explained using the rate of living theory…

Auditing Membership Leakages of Multi-Exit Networks Open

Zheng Li, Yiyong Liu, Xinlei He, Yu Ning, Michael Backes , et al. · 2023

Relying on the fact that not all inputs require the same amount of computation to yield a confident prediction, multi-exit networks are gaining attention as a prominent approach for pushing the limits of efficient deployment. Multi-exit ne…

Membership Inference Attacks by Exploiting Loss Trajectory Open

Yiyong Liu, Zhengyu Zhao, Michael Backes, Yang Zhang · 2022

Machine learning models are vulnerable to membership inference attacks in which an adversary aims to predict whether or not a particular sample was contained in the target model’s training dataset. Existing attack methods have commonly exp…

Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Background Caenorhabditis elegans is an excellent research model whose populations have been used in many studies to address various biological questions. Although worm-to-worm phenotypic variations in isogenic populations have been persis…

Molecular identification and phylogenesis analysis of gastrointestinal nematode in different populations of Kazakh sheep Open

Xiaofei Yan, Sangang He, Yiyong Liu, Bing Han, Ning Zhang , et al. · 2022

Three dominant species of gastrointestinal nematodes, Haemonchus contortus , Trichostrongylus spp., and Teladorsagia circumcincta from the various populations of Kazakh sheep were subjected to molecular identification and phylogenetic anal…

Membership Inference Attacks by Exploiting Loss Trajectory Open

Yiyong Liu, Zhengyu Zhao, Michael Backes, Shuicheng Yan · 2022

Machine learning models are vulnerable to membership inference attacks in which an adversary aims to predict whether or not a particular sample was contained in the target model's training dataset. Existing attack methods have commonly exp…

Correction: An epidemiological study of gastrointestinal nematode and Eimeria coccidia infections in different populations of Kazakh sheep Open

Xiaofei Yan, Mingjun Liu, Sangang He, Ting Tong, Yiyong Liu , et al. · 2022

[This corrects the article DOI: 10.1371/journal.pone.0251307.].

Effect Analyses of Thermal Deformation on Magnetic Performance of the CPMU Prototype in SSRF Open

Jian Wang, Li Wang, Yiyong Liu, Wei Zhang · 2022

A cryogenic permanent magnet undulator (CPMU) prototype cooled by sub-cooled liquid nitrogen was developed in Shanghai Synchrotron Radiation Facility (SSRF) in 2016. The CPMU prototype mainly consist of NdFeB based hybrid magnet arrays wit…

Neuronal GPCR NMUR-1 regulates distinct immune responses to different pathogens Open

Phillip Wibisono, Shawndra Wibisono, Jan Watteyne, Chia‐Hui Chen, Durai Sellegounder , et al. · 2022

Additional file 6 of Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Additional file 6: Table S5. Enriched biological processes revealed by single-worm RNA-seq (infected samples relative to uninfected samples).

Additional file 5 of Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Additional file 5: Table S4. Enriched biological processes revealed by single-worm RNA-seq relative to standard RNA-seq.

Additional file 8 of Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Additional file 8: Table S7. Enriched biological processes revealed by standard RNA-seq (infected samples relative to uninfected samples).

Additional file 9 of Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Additional file 9: Table S8. Attenuated biological processes revealed by standard RNA-seq (infected samples relative to uninfected samples).

Additional file 7 of Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Additional file 7: Table S6. Attenuated biological processes revealed by single-worm RNA-seq (infected samples relative to uninfected samples).

Additional file 4 of Using single-worm RNA sequencing to study C. elegans responses to pathogen infection Open

Archer J. Wang, Phillip Wibisono, Blake M. Geppert, Yiyong Liu · 2022

Additional file 4: Table S3. Enriched biological processes revealed by standard RNA-seq relative to single-worm RNA-seq.

The longevity response to warm temperature is neurally controlled via the regulation of collagen genes Open

Sankara Naynar Palani, Durai Sellegounder, Yiyong Liu · 2021

Studies in diverse species have associated higher temperatures with shorter lifespan and lower temperatures with longer lifespan. However, the mechanisms behind these inverse effects of temperature on longevity are not well understood. Her…

The neuronal GPCR OCTR-1 mediates temperature effects on longevity by regulating immune response genes inC. elegans Open

Shawndra Wibisono, Phillip Wibisono, Chia-Hui Chen, Jingru Sun, Yiyong Liu · 2021

Researchers have long known that many animals live longer in colder climates than in warmer climates. The inverse relationship between temperature and lifespan was traditionally explained using the rate of living theory, which suggests tha…

Detection of Pathogens and Regulation of Immunity by the Caenorhabditis elegans Nervous System Open

Yiyong Liu, Jingru Sun · 2021

Although Caenorhabditis elegans has been used as a model host for studying host-pathogen interactions for more than 20 years, the mechanisms by which it identifies pathogens are not well understood. This is largely due to its lack of most …

A novel in vitro Caenorhabditis elegans transcription system Open

Phillip Wibisono, Yiyong Liu, Jingru Sun · 2020

Background Caenorhabditis elegans is an excellent model organism for biological research, but its contributions to biochemical elucidation of eukaryotic transcription mechanisms have been limited. One of the biggest obstacles for C. elegan…

Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway Open

Yiyong Liu, Yanan Fang, Hongbing Shao, Laura A. Lindsey‐Boltz, Aziz Sancar , et al. · 2020

At clinically relevant doses, chemotherapeutic SN1 DNA methylating agents induce an ATR-mediated checkpoint response in human cells that is dependent on functional MutSα and MutLα. Deficiency of either mismatch repair activity renders cell…

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