Explanipedia

Determinants Impacting Daily Physical Activity Levels Among Chinese Adults and Its Association with Obesity Open

Yizhi Tang, S. Ruan, Xinyu Zhou, Junyang Chen, Qi Zhu · 2025

Background/Objectives: This study investigated the influencing factors of daily physical activity among Chinese adults and its association with obesity. Methods: A nationwide online questionnaires survey was conducted using Question star, …

Identification of Outer Membrane Vesicles as a New Vehicle Mediating Antibiotic Resistance Gene Transfer in Campylobacter Open

Mengyu Zhao, Xiaolong Lin, Ke Wu, Haozheng Li, Changwei Lei , et al. · 2025

The emergence and worldwide dissemination of antibiotic resistance genes (ARGs) compromise antibiotic therapy and are a major public health crisis. Horizontal gene transfer (HGT) plays a major role in the spread of ARGs among bacterial pat…

A comprehensive PDCoV-host proteome interaction map reveals potential antiviral targets Open

Wenjun Yan, Kailu Wang, Song Liu, Rongbin Qiu, Qingcheng Yang , et al. · 2025

Porcine deltacoronavirus (PDCoV), an enteric member of the coronavirus family, has emerged globally over the past decade, causing significant impacts on the swine industry. While studies of virus-host protein interactions provide crucial i…

Unveiling a Novel Mechanism of Enhanced Secretion, Cargo Loading, and Accelerated Dynamics of Bacterial Extracellular Vesicles Following Antibiotic Exposure Open

Jinpeng Li, Chao Li, Han Yun, Yulian Hu, Jian Yang , et al. · 2025

Antibiotic exposure substantially alters the production mechanisms of bacterial extracellular vesicles (BEVs), which serve as carriers for intercellular exchange of DNA, proteins, and nutrients, yet the underlying mechanisms remain elusive…

Genomic adaptation of Clostridium perfringens to human intestine Open

Ke Wu, Juan Wang, Zelin Yan, Yanyan Zhu, Shaolin Wang , et al. · 2024

Clostridium perfringens is often associated with foodborne diseases, posing significant public health risks. However, genomic investigation of C. perfringens isolates from the human population has been lacking. This study aims to fill this…

Field Investigation of the Dynamic Response of Culvert–Embankment–Culvert Transitions in a High-Speed Railway Open

Ping Hu, Huo Liu, Yizhi Tang, Yu-liang Lin · 2023

The stiffnesses of embankments and culverts differ in the transition sections of high-speed railways (HSRs) due to their different supporting conditions. The dynamic irregularity caused by the different stiffnesses makes this transition ar…

“Negative Capability”: Imagination in Ode to a Nightingale Open

Yizhi Tang · 2023

Keats was one of the most famous English Romantic poets of the 19th century. Although he had a difficult life and died young, Keats still produced many unsurpassed works in his short life, and even today, his achievements shine like a star…

Insights on genetic characterization and pathogenesis of a GI-19 (QX-like) infectious bronchitis virus isolated in China Open

Wenjun Yan, Qingcheng Yang, Siyu Huang, Song Liu, Kailu Wang , et al. · 2023

Comparative Analysis of Phylogenetic Relationships and Virulence Factor Characteristics between Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates Derived from Clinical Sites and Chicken Farms Open

Chao Li, Xuan Chen, Zijing Ju, Cui Li, Ying Xu , et al. · 2022

Bacterial drug resistance has become one of the most significant threats to human health worldwide, especially for extended-spectrum β-lactamase-producing E. coli (ESBL- E. coli ). Timely and accurate epidemiological surveys can provide sc…

Chicken interferon-induced transmembrane protein 1 promotes replication of coronavirus infectious bronchitis virus in a cell-specific manner Open

Hao Li, Ruiqi Ni, Kailu Wang, Yiming Tian, Huilin Gong , et al. · 2022

Withdrawal of antibiotic growth promoters in China and its impact on the foodborne pathogen Campylobacter coli of swine origin Open

Renqiao Wen, Chao Li, Mengyu Zhao, Hongning Wang, Yizhi Tang · 2022

Antibiotic growth promoters (AGPs) have been used as feed additives to improve feed efficiency in food animals for more than six decades. However, the wide use of AGPs has led to the emergence of antibiotic-resistant pathogens of animal or…

Pathogen-Specific Bactericidal Method Mediated by Conjugative Delivery of CRISPR-Cas13a Targeting Bacterial Endogenous Transcripts Open

Zihao Song, Yue Yu, Xinpeng Bai, Yiguo Jia, Jiayi Tian , et al. · 2022

Antibiotics with broad-spectrum activities are known to disturb both pathogens and beneficial gut microbiota and cause many undesired side effects, prompting increased interest in developing therapies that specifically eliminate pathogenic…

TENET: Transformer Encoding Network for Effective Temporal Flow on Motion Prediction Open

Yuting Wang, Hangning Zhou, Zhigang Zhang, Feng Chen, Huadong Lin , et al. · 2022

This technical report presents an effective method for motion prediction in autonomous driving. We develop a Transformer-based method for input encoding and trajectory prediction. Besides, we propose the Temporal Flow Header to enhance the…

Risk Coupling Evaluation of Social Stability of Major Engineering Based on N-K Model Open

Hongyan Yan, Zhouwei Zheng, Hanjie Huang, Xinyi Zhou, Yizhi Tang , et al. · 2022

In view of the sociality, complexity, and uncertainty of major engineering projects, social stability poses many problems for social contradictions and conflicts in the whole life cycle of the project. This study aimed to investigate the a…

Outer Membrane Vesicles of Avian PathogenicEscherichia coli Mediate the Horizontal Transmission of blaCTX-M-55 Open

Chao Li, Renqiao Wen, Rongrong Mu, Xuan Chen, Peng Ma , et al. · 2022

The CTX-M-55 type extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae is increasing in prevalence worldwide without the transmission mechanism being fully clarified, which threatens public and livestock health. Outer membrane…

Development of nanobody-horseradish peroxidase-based sandwich ELISA to detect Salmonella Enteritidis in milk and in vivo colonization in chicken Open

Kui Gu, Zengxu Song, Changyu Zhou, Peng Ma, Chao Li , et al. · 2022

Immunocapture Magnetic Beads Enhanced the LAMP-CRISPR/Cas12a Method for the Sensitive, Specific, and Visual Detection of Campylobacter jejuni Open

Chao Li, Xuan Chen, Renqiao Wen, Peng Ma, Kui Gu , et al. · 2022

Campylobacter jejuni is one of the most important causes of food-borne infectious disease, and poses challenges to food safety and public health. Establishing a rapid, accurate, sensitive, and simple detection method for C. jejuni enables …

Identification of Three Novel PmGRI1 Genomic Resistance Islands and One Multidrug Resistant Hybrid Structure of Tn7-like Transposon and PmGRI1 in Proteus mirabilis Open

Boheng Ma, Xuechun Wang, Changwei Lei, Yizhi Tang, Juan He , et al. · 2021

The widespread use of antibiotics in large-scale livestock production has led to serious antibiotic resistance. Proteus mirabilis is an important pathogenic bacterium on large-scale farms. Chromosomally localized mobilizable genetic elemen…

Preventive Antibiotic Treatment Increases Susceptibility of Neonatal chicks to Salmonella Infection via Disrupting Gut Microbiota and Linoleic Acid Metabolis Open

Xueran Mei, Boheng Ma, Xiwen Zhai, Anyun Zhang, Changwei Lei , et al. · 2020

Background: Antibiotics are widely employed in animal husbandry to prevent and treat diseases. Increasing evidence suggests they may alter the animals’ natural microbiota and increase their susceptibility to pathogen. However, the mechanis…

Preventive Antibiotic Treatment Increases Neonatal Chicks Susceptibility to Salmonella Infection Via Disrupting Gut Microbiota and Linoleic Acid Metabolism Open

Xueran Mei, Boheng Ma, Xiwen Zhai, Anyun Zhang, Changwei Lei , et al. · 2020

Background: Antimicrobial agents have been widely used in animal farms to prevent and treat animal diseases. However, antimicrobial agents may change the bacterial community and increase susceptibility to the pathogenic bacteria infection.…

Emergence of fexA in Mediating Resistance to Florfenicols in Campylobacter Open

Biao Tang, Yizhi Tang, Ling Zhang, Xiao Liu, Jiang Chang , et al. · 2020

Florfenicol belongs to a class of phenicol antimicrobials widely used as feed additives and for the treatment of respiratory infections. In recent years, increasing resistance to florfenicol has been reported in Campylobacter spp., the lea…

HIV positive secondary gastric syphilis with Helicobacter Pylori infection, a case report and literature review Open

Jingli Zhang, Na Wei, Weifeng Li, Qun Huang, Guoqing Hu , et al. · 2020

Gastric syphilis is an uncommon disease, presenting nonspecific clinical and histological features.We present a rare case of 17-year-old women who had 2-week abdominal pain and sought for medical help.The patient was diagnosed with gastric…

High Prevalence of Fluoroquinolone-Resistant Campylobacter Bacteria in Sheep and Increased Campylobacter Counts in the Bile and Gallbladders of Sheep Medicated with Tetracycline in Feed Open

Jing Xia, Jinji Pang, Yizhi Tang, Zuowei Wu, Lei Dai , et al. · 2019

Campylobacter is a major cause of foodborne illness in humans, and antibiotic-resistant Campylobacter is considered a serious threat to public health in the United States and worldwide. As a foodborne pathogen, Campylobacter commonly exist…

Antibiotic resistance trends and mechanisms in the foodborne pathogen,Campylobacter Open

Yizhi Tang, Liang‐Xing Fang, Changyun Xu, Qijing Zhang · 2017

Campylobacter is a major foodborne pathogen and is commonly present in food producing animals. This pathogenic organism is highly adaptable and has become increasingly resistant to various antibiotics. Recently, both the Centers for Diseas…

A Mutator Phenotype Promoting the Emergence of Spontaneous Oxidative Stress-Resistant Mutants in Campylobacter jejuni Open

Lei Dai, Orhan Şahin, Yizhi Tang, Qijing Zhang · 2017

Campylobacter jejuni is a leading cause of foodborne illnesses worldwide. As a microaerophilic organism, C. jejuni must be able to defend against oxidative stress encountered both in the host and in the environment. How Campylobacter utili…

Wide but Variable Distribution of a Hypervirulent Campylobacter jejuni Clone in Beef and Dairy Cattle in the United States Open

Yizhi Tang, Richard J. Meinersmann, Orhan Şahin, Zuowei Wu, Lei Dai , et al. · 2017

Campylobacter jejuni clone SA is the major cause of sheep abortion and contributes significantly to foodborne illnesses in the United States. Clone SA is hypervirulent because of its distinct ability to produce systemic infection and its p…

Key Role of Capsular Polysaccharide in the Induction of Systemic Infection and Abortion by Hypervirulent Campylobacter jejuni Open

Orhan Şahin, Samantha Terhorst, Eric Burrough, Zhangqi Shen, Zuowei Wu , et al. · 2017

Campylobacter jejuni is a zoonotic pathogen, and a hypervirulent clone, named clone SA, has recently emerged as the predominant cause of ovine abortion in the United States. To induce abortion, orally ingested Campylobacter must translocat…

Rising fluoroquinolone resistance in Campylobacter isolated from feedlot cattle in the United States Open

Yizhi Tang, Orhan Şahin, Nada Pavlovic, Jeff LeJeune, James R. Carlson , et al. · 2017

Emergence of a plasmid-borne multidrug resistance gene cfr(C) in foodborne pathogen Campylobacter Open

Yizhi Tang, Lei Dai, Orhan Şahin, Zuowei Wu, Mingyuan Liu , et al. · 2017

These results identify cfr (C) as a new multidrug resistance mechanism in Campylobacter and suggest the potential transmission of this mechanism via the foodborne route, warranting enhanced efforts to monitor its spread in Campylobacter an…

Campylobacter in cattle: molecular epidemiology and antibiotic resistance Open

Yizhi Tang · 2017

Ruminant Campylobacter, (C. jejuni and C. coli), contributes significantly to foodborne illnesses in humans. A recently emerged C. jejuni clone (named SA) is also a major cause of ruminant abortion in the United States. Despite the importa…

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