Yohann Clément
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View article: Using suspect and non-targeted analysis (NTA) by high-resolution mass spectrometry to gain deeper insight into organic contamination of freshwater sediments
Using suspect and non-targeted analysis (NTA) by high-resolution mass spectrometry to gain deeper insight into organic contamination of freshwater sediments Open
Synthetic organic micropollutants produced and used worldwide ultimately find their way into aquatic ecosystems through wastewater discharge and surface runoff. This contamination can migrate into sediment, where it forms archives. The pot…
View article: Metabolomic and Lipidomic Alterations in Patients with Atopic Dermatitis with Dupilumab-Associated Ocular Surface Disease
Metabolomic and Lipidomic Alterations in Patients with Atopic Dermatitis with Dupilumab-Associated Ocular Surface Disease Open
View article: Advancing Specific Local Wine Identification Through Integration of Icp-Ms Mineral Wine Profiles and Artificial Intelligence: A Case Study on Discrimination Among the Ten Beaujolais Crus
Advancing Specific Local Wine Identification Through Integration of Icp-Ms Mineral Wine Profiles and Artificial Intelligence: A Case Study on Discrimination Among the Ten Beaujolais Crus Open
View article: Enhancing wine authentication: leveraging 12,000+ international mineral wine profiles and artificial intelligence for accurate origin and variety prediction
Enhancing wine authentication: leveraging 12,000+ international mineral wine profiles and artificial intelligence for accurate origin and variety prediction Open
For the wine industry, ensuring quality and authenticity hinges on the precise determination of wine origin. In our study, we developed a fast semi-quantitative method to analyse 41 chemical elements in wine, employing inductively coupled …
View article: Concomitant investigation of crustacean amphipods lipidome and metabolome during the molting cycle by Zeno SWATH data-independent acquisition coupled with electron activated dissociation and machine learning
Concomitant investigation of crustacean amphipods lipidome and metabolome during the molting cycle by Zeno SWATH data-independent acquisition coupled with electron activated dissociation and machine learning Open
Reproducible detection of features and confident identification of putative compounds are pivotal stages within analytical pipelines. The DIA approach combined with Zeno pulsing enhances detection sensitivity and targeted fragmentation wit…
View article: Electron-activated dissociation (EAD) for the complementary annotation of metabolites and lipids through data-dependent acquisition analysis and feature-based molecular networking, applied to the sentinel amphipod Gammarus fossarum
Electron-activated dissociation (EAD) for the complementary annotation of metabolites and lipids through data-dependent acquisition analysis and feature-based molecular networking, applied to the sentinel amphipod Gammarus fossarum Open
View article: Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model of ischemia-reperfusion injury
Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model of ischemia-reperfusion injury Open
View article: Concomitant investigation of crustacean amphipods lipidome and metabolome during molting stage by Zeno SWATH Data-Independent Acquisition coupled with Electron Activated Dissociation and machine learning
Concomitant investigation of crustacean amphipods lipidome and metabolome during molting stage by Zeno SWATH Data-Independent Acquisition coupled with Electron Activated Dissociation and machine learning Open
Background DIA (Data-Independent Acquisition) is a powerful technique in Liquid Chromatography coupled with high-resolution tandem Mass Spectrometry (LC-MS/MS) in metabolomics and lipidomics, for comprehensive profiling of molecules in bio…
View article: Artificial Intelligence for reverse engineering: application to detergents using Raman spectroscopy
Artificial Intelligence for reverse engineering: application to detergents using Raman spectroscopy Open
The reverse engineering of a complex mixture, regardless of its nature, has become significant today. Being able to quickly assess the potential toxicity of new commercial products in relation to the environment presents a genuine analytic…
View article: Une situation pédagogique sur microcontrôleur pour faire émerger les besoins en analyse de données - le tri des matières plastiques
Une situation pédagogique sur microcontrôleur pour faire émerger les besoins en analyse de données - le tri des matières plastiques Open
View article: Ultraviolet exposure regulates skin metabolome based on the microbiome
Ultraviolet exposure regulates skin metabolome based on the microbiome Open
View article: Challenges and perspectives in MS-based omics approaches for ecotoxicology studies: An insight on Gammarids sentinel amphipods
Challenges and perspectives in MS-based omics approaches for ecotoxicology studies: An insight on Gammarids sentinel amphipods Open
The aquatic environment is one of the most complex biosystems, as organism at all trophic levels may be exposed to a multitude of pollutants. As major goals, ecotoxicology typically investigates the impact of toxic pollutants on the ecosys…
View article: Artificial Intelligence for Reverse Engineering:Application to Detergents Using Raman Spectroscopy
Artificial Intelligence for Reverse Engineering:Application to Detergents Using Raman Spectroscopy Open
View article: Early detection of ureteropelvic junction obstruction in neonates with prenatal diagnosis of renal pelvis dilatation using 1H NMR urinary metabolomics
Early detection of ureteropelvic junction obstruction in neonates with prenatal diagnosis of renal pelvis dilatation using 1H NMR urinary metabolomics Open
Renal pelvis dilatation (RPD) is diagnosed in utero on prenatal ultrasonography (US) and can resolve spontaneously. However, isolated RPD can also reflect ureteropelvic junction obstruction (UPJO), which requires surgical treatment to prev…
View article: Determination of enantiomeric and stable isotope ratio fingerprints of active secondary metabolites in neroli (Citrus aurantium L.) essential oils for authentication by multidimensional gas chromatography and GC-C/P-IRMS
Determination of enantiomeric and stable isotope ratio fingerprints of active secondary metabolites in neroli (Citrus aurantium L.) essential oils for authentication by multidimensional gas chromatography and GC-C/P-IRMS Open
View article: Orbitool: a software tool for analyzing online Orbitrap mass spectrometry data
Orbitool: a software tool for analyzing online Orbitrap mass spectrometry data Open
The Orbitrap mass spectrometer has recently been proved to be a powerful instrument to accurately measure gas-phase and particle-phase organic compounds with a greater mass resolving power than other widely used online mass spectrometers i…
View article: Multi-element (13C, 2H and 34S) bulk and compound-specific stable isotope analysis for authentication of Allium species essential oils
Multi-element (13C, 2H and 34S) bulk and compound-specific stable isotope analysis for authentication of Allium species essential oils Open
View article: Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition
Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition Open
View article: Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in lipid composition in<i>Gammarus fossarum</i>
Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in lipid composition in<i>Gammarus fossarum</i> Open
Summary Sentinel species are playing an indispensable role in monitoring environmental pollution in aquatic ecosystems. Many pollutants found in water prove to be endocrine disrupting chemicals that could cause disruptions in lipid homeost…
View article: Orbitool: A software tool for analyzing online Orbitrap mass spectrometry data
Orbitool: A software tool for analyzing online Orbitrap mass spectrometry data Open
The Orbitrap mass spectrometer has recently been proved to be a powerful instrument to accurately measure gas-phase and particle-phase organic compounds with a greater mass resolving power than other widely-used online mass spectrometers i…
View article: Controlled Release of Retinol in Cationic Co-Polymeric Nanoparticles for Topical Application
Controlled Release of Retinol in Cationic Co-Polymeric Nanoparticles for Topical Application Open
Retinol is a compound used in many skin care formulations to act against skin conditions like acne, wrinkles, psoriasis, and ichthyosis. While retinol is used as an active ingredient, its efficacy is limited by an extreme sensitivity to li…
View article: In situ isobaric lipid mapping by MALDI–ion mobility separation–mass spectrometry imaging
In situ isobaric lipid mapping by MALDI–ion mobility separation–mass spectrometry imaging Open
The highly diverse chemical structures of lipids make their analysis directly from biological tissue sections extremely challenging. Here, we report the in situ mapping and identification of lipids in a freshwater crustacean Gammarus fossa…
View article: Shotgun Lipidomics and Mass Spectrometry Imaging Unveil Diversity and Dynamics in Lipid Composition in <i>Gammarus Fossarum</i>
Shotgun Lipidomics and Mass Spectrometry Imaging Unveil Diversity and Dynamics in Lipid Composition in <i>Gammarus Fossarum</i> Open
View article: Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure–Activity Relationship) Models
Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure–Activity Relationship) Models Open
Besides their established antioxidant activity, many phenolic compounds may exhibit significant antibacterial activity. Here, the effect of a large dataset of 35 polyphenols on the growth of 6 foodborne pathogenic or food-spoiling bacteria…
View article: Ultrasensitive Immunosensor Array for TNF-α Detection in Artificial Saliva using Polymer-Coated Magnetic Microparticles onto Screen-Printed Gold Electrode
Ultrasensitive Immunosensor Array for TNF-α Detection in Artificial Saliva using Polymer-Coated Magnetic Microparticles onto Screen-Printed Gold Electrode Open
Tumor necrosis factor-α (TNF-α) is a biomarker of inflammation that occurs in patients suffering from heart failure (HF). Saliva can be sampled in a non-invasive way, and it is currently gaining importance as matrix alternative to blood in…
View article: Effect of interactions of plant phenolics with bovine meat proteins on their antibacterial activity
Effect of interactions of plant phenolics with bovine meat proteins on their antibacterial activity Open
View article: Heavy Metal Pollution of Chari River Water during the Crossing of N’Djamena (Chad)
Heavy Metal Pollution of Chari River Water during the Crossing of N’Djamena (Chad) Open
This study was carried out to identify and assess the water quality of the Chari River. The Chari, 1200 km long, is Chad’s major water source. Municipal sewage, industrial wastewater discharge, and seasonal run-off from agriculture are reg…
View article: A Highly Sensitive Potentiometric Amphetamine Microsensor Based on All-Solid-State Membrane Using a New Ion-Par Complex, [3,3′-Co(1,2-closo-C2B9H11)2]− C9H13NH+
A Highly Sensitive Potentiometric Amphetamine Microsensor Based on All-Solid-State Membrane Using a New Ion-Par Complex, [3,3′-Co(1,2-closo-C2B9H11)2]− C9H13NH+ Open
In the present work a highly sensitive ion-selective microelectrode for the detection of amphetamine is presented. For this purpose, a novel ion-par complex based on the metallocarborane, cobalt bis(dicarbollide) anion ([3,3′-Co(1,2-C2B9H1…
View article: Polyamide Microparticles Containing Vitamin C by Interfacial Polymerization: An Approach by Design of Experimentation
Polyamide Microparticles Containing Vitamin C by Interfacial Polymerization: An Approach by Design of Experimentation Open
Vitamin C is widely use in cosmetics and pharmaceutics products for its active properties. However ascorbic acid shows unfavourable chemical instability such as oxidation leading to formulation problems. Therefore, carriers, such as micro-…