Yoko Mikami
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View article: Machine learning prediction of atrial fibrillation in cardiovascular patients using cardiac magnetic resonance and electronic health information
Machine learning prediction of atrial fibrillation in cardiovascular patients using cardiac magnetic resonance and electronic health information Open
Background Atrial fibrillation (AF) is a commonly encountered cardiac arrhythmia associated with morbidity and substantial healthcare costs. While patients with cardiovascular disease experience the greatest risk of new-onset AF, no risk m…
View article: Influence of Sex-Based Differences in Cardiac Phenotype on Atrial Fibrillation Recurrence in Patients Undergoing Pulmonary Vein Isolation
Influence of Sex-Based Differences in Cardiac Phenotype on Atrial Fibrillation Recurrence in Patients Undergoing Pulmonary Vein Isolation Open
Background Pulmonary vein isolation (PVI) is a commonly engaged therapy for symptomatic atrial fibrillation (AF). Prior studies have documented elevated AF recurrence rates among females vs. males. Sex-specific mechanisms underlying this p…
View article: Machine Learning Patient-Specific Prediction of Heart Failure Hospitalization Using Cardiac MRI-Based Phenotype and Electronic Health Information
Machine Learning Patient-Specific Prediction of Heart Failure Hospitalization Using Cardiac MRI-Based Phenotype and Electronic Health Information Open
Background Heart failure (HF) hospitalization is a dominant contributor of morbidity and healthcare expenditures in patients with systolic HF. Cardiovascular magnetic resonance (CMR) imaging is increasingly employed for the evaluation of H…
View article: Study of Rapid HPLC Method for the Determination of Antioxidants in Foods, and Standard Solution Stability during Storage
Study of Rapid HPLC Method for the Determination of Antioxidants in Foods, and Standard Solution Stability during Storage Open
In this study, we simultaneously determined three antioxidants, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), and tert-butylhydroquinone (TBHQ), using HPLC equipped both with a photodiode array detector and a fluorescence…
View article: Mid-wall striae fibrosis predicts heart failure admission, composite heart failure events, and life-threatening arrhythmias in dilated cardiomyopathy
Mid-wall striae fibrosis predicts heart failure admission, composite heart failure events, and life-threatening arrhythmias in dilated cardiomyopathy Open
View article: Prevalence and predictors of right ventricular dysfunction in cancer patients treated with cardiotoxic chemotherapy – a prospective cardiovascular magnetic resonance study
Prevalence and predictors of right ventricular dysfunction in cancer patients treated with cardiotoxic chemotherapy – a prospective cardiovascular magnetic resonance study Open
Background Right ventricular (RV) function has an established incremental prognostic value in cardiomyopathy. Studies on cancer therapeutics-related cardiac dysfunction (CTRCD) primarily focused on the left ventricle (LV), with conflicting…
View article: Cardiac remodelling predicts outcome in patients with chronic heart failure
Cardiac remodelling predicts outcome in patients with chronic heart failure Open
Aims Surveillance imaging is often used to detect remodelling, a change in cardiac geometry, and/or function; however, there are limited data in patients with chronic heart failure (HF). We sought to characterize cardiac remodelling in pat…
View article: Effect of Active Cancer on the Cardiac Phenotype: A Cardiac Magnetic Resonance Imaging‐Based Study of Myocardial Tissue Health and Deformation in Patients With Chemotherapy‐Naïve Cancer
Effect of Active Cancer on the Cardiac Phenotype: A Cardiac Magnetic Resonance Imaging‐Based Study of Myocardial Tissue Health and Deformation in Patients With Chemotherapy‐Naïve Cancer Open
Background The overlap between cancer and cardiovascular care continues to expand, with intersections emerging before, during, and following cancer therapies. To date, emphasis has been placed on how cancer therapeutics influence downstrea…
View article: Right ventricular insertion site fibrosis in a dilated cardiomyopathy referral population: phenotypic associations and value for the prediction of heart failure admission or death
Right ventricular insertion site fibrosis in a dilated cardiomyopathy referral population: phenotypic associations and value for the prediction of heart failure admission or death Open
RVI site fibrosis in the absence of MWS fibrosis is associated with bi-ventricular remodelling and intermediate risk of heart failure admission or death. Our study findings suggest RVI site fibrosis to be pre-requisite for the incremental …
View article: Right Ventricular Ejection Fraction for the Prediction of Major Adverse Cardiovascular and Heart Failure-Related Events
Right Ventricular Ejection Fraction for the Prediction of Major Adverse Cardiovascular and Heart Failure-Related Events Open
Background: There is increasing evidence that right ventricular ejection fraction (RVEF) may provide incremental value to left ventricular (LV) ejection fraction for the prediction of major adverse cardiovascular events. To date, generaliz…
View article: Identifying the value of RVEF for the prediction of major cardiovascular outcomes: a study of 7,131 patients undergoing cardiovascular magnetic resonance imaging
Identifying the value of RVEF for the prediction of major cardiovascular outcomes: a study of 7,131 patients undergoing cardiovascular magnetic resonance imaging Open
Background Right ventricular (RV) function remains poorly recognized for its value in predicting cardiovascular events at a population level. Cardiovascular Magnetic Resonance (CMR) imaging is the gold standard for RV assessment. Purpose T…
View article: Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury
Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury Open
Coronary heart disease is a leading cause of death. Tissue remodeling and fibrosis results in cardiac pump dysfunction and ischemic heart failure. Cardiac fibroblasts may rebuild damaged tissues when prompted by suitable environmental cues…
View article: Sex-specific relationships between patterns of ventricular remodelling and clinical outcomes
Sex-specific relationships between patterns of ventricular remodelling and clinical outcomes Open
Aims Left ventricular hypertrophy (LVH) is the most common form of myocardial remodelling and predicts adverse outcomes in patients with coronary artery disease (CAD). However, sex-specific prevalence and prognostic significance of LVH pat…
View article: Layer-specific strain in patients with heart failure using cardiovascular magnetic resonance: not all layers are the same
Layer-specific strain in patients with heart failure using cardiovascular magnetic resonance: not all layers are the same Open
Global strains measured on endocardium, epicardium or averaged across the wall thickness are not equivalent for the identification of systolic dysfunction or outcomes prediction in HF. The endocardium-specific strains were shown to have po…
View article: Natural History of Myocardial Injury and Chamber Remodeling in Acute Myocarditis
Natural History of Myocardial Injury and Chamber Remodeling in Acute Myocarditis Open
Background: Cardiovascular magnetic resonance (CMR) imaging is commonly used to diagnose acute myocarditis. However, the natural history of CMR-based tissue markers and their association with left ventricular recovery is poorly explored. W…
View article: Cardiovascular risk is associated with a transmural gradient of myocardial oxygenation during adenosine infusion
Cardiovascular risk is associated with a transmural gradient of myocardial oxygenation during adenosine infusion Open
Aims In patients with coronary artery disease (CAD), a transmural gradient of myocardial perfusion has been repeatedly observed, with the subendocardial layer showing more pronounced perfusion deficits. Oxygenation-sensitive cardiovascular…
View article: Effects of age, gender, and risk‐factors for heart failure on native myocardial T<sub>1</sub> and extracellular volume fraction using the SASHA sequence at 1.5T
Effects of age, gender, and risk‐factors for heart failure on native myocardial T<sub>1</sub> and extracellular volume fraction using the SASHA sequence at 1.5T Open
View article: Clinical feasibility and validation of 3D principal strain analysis from cine MRI: comparison to 2D strain by MRI and 3D speckle tracking echocardiography
Clinical feasibility and validation of 3D principal strain analysis from cine MRI: comparison to 2D strain by MRI and 3D speckle tracking echocardiography Open
View article: The Prognostic Significance of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Patients with Non-ischemic Cardiomyopathy
The Prognostic Significance of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Patients with Non-ischemic Cardiomyopathy Open
Late Gadolinium Enhanced (LGE) Cardiovascular Magnetic Resonance (CMR) imaging has a unique ability to characterize diverse mechanisms of non-ischemic myocardial injury. The pattern and extent of LGE findings have been studied across a wid…
View article: Right Ventricular Ejection Fraction Is Incremental to Left Ventricular Ejection Fraction for the Prediction of Future Arrhythmic Events in Patients With Systolic Dysfunction
Right Ventricular Ejection Fraction Is Incremental to Left Ventricular Ejection Fraction for the Prediction of Future Arrhythmic Events in Patients With Systolic Dysfunction Open
Background— Left ventricular ejection fraction remains the primary risk stratification tool used in the selection of patients for implantable cardioverter defibrillator therapy. However, this solitary marker fails to identify a substantial…
View article: Markers of abnormal tissue deformation and fibrosis in remote myocardium following acute myocardial infarction: a comparison of diabetics versus non-diabetics performed using spatially matched 4D strain and native T1 mapping
Markers of abnormal tissue deformation and fibrosis in remote myocardium following acute myocardial infarction: a comparison of diabetics versus non-diabetics performed using spatially matched 4D strain and native T1 mapping Open
View article: Relative influence of peak strain delay and peak strain amplitude of non-scarred myocardium in response to cardiac resynchronization therapy: insights from segmental 4D strain analysis
Relative influence of peak strain delay and peak strain amplitude of non-scarred myocardium in response to cardiac resynchronization therapy: insights from segmental 4D strain analysis Open
Background The burden and location of replacement fibrosis by Late Gadolinium Enhancement (LGE) MRI is a recognized predictor of non-response in patients undergoing cardiac resynchronization therapy (CRT). However, the capacity of the non-…
View article: Comparison of Semi-automated Late Gadolinium Enhancement Quantification Techniques in Measuring Septal Fibrosis in Patients with Dilated Non-Ischemic Cardiomyopathy
Comparison of Semi-automated Late Gadolinium Enhancement Quantification Techniques in Measuring Septal Fibrosis in Patients with Dilated Non-Ischemic Cardiomyopathy Open
View article: Inter-center variability in the application of the Lake Louise Criteria to the diagnosis of myocarditis
Inter-center variability in the application of the Lake Louise Criteria to the diagnosis of myocarditis Open
View article: Left atrial volume and function are predictive of cardiac death or appropriate device therapy in patients with non-ischemic dilated cardiomyopathy
Left atrial volume and function are predictive of cardiac death or appropriate device therapy in patients with non-ischemic dilated cardiomyopathy Open
View article: Do whole body impedance cardiography estimates of left ventricular structure, volumes and function correlate with the gold standard of cardiac magnetic resonance imaging?
Do whole body impedance cardiography estimates of left ventricular structure, volumes and function correlate with the gold standard of cardiac magnetic resonance imaging? Open
View article: Refining the characterization of residual function in hypertrophic cardiomyopathy through remote segment 4D strain analysis
Refining the characterization of residual function in hypertrophic cardiomyopathy through remote segment 4D strain analysis Open
View article: 4D strain analysis within non-infarcted myocardium of patients with ischemic cardiomyopathy: potential marker for the prediction of adverse cardiac events
4D strain analysis within non-infarcted myocardium of patients with ischemic cardiomyopathy: potential marker for the prediction of adverse cardiac events Open
View article: Segmental strain analysis by deformation of a mesh model: comparison of segmental strain metrics and late gadolinium enhancement quantification in myocardial infarction
Segmental strain analysis by deformation of a mesh model: comparison of segmental strain metrics and late gadolinium enhancement quantification in myocardial infarction Open
Background The presence and transmurality of posterolateral scar within the left ventricle by late gadolinium enhancement (LGE) imaging has been shown to portend poor response to cardiac resynchronization therapy due to placement of the LV…
View article: Objective criteria for septal fibrosis in non-ischemic dilated cardiomyopathy: validation for the prediction of future cardiovascular events
Objective criteria for septal fibrosis in non-ischemic dilated cardiomyopathy: validation for the prediction of future cardiovascular events Open
Novice readers were able to achieve superior risk prediction for future cardiovascular events versus experts using objective criteria for septal fibrosis in patients with NIDCM. Patients with a septal fibrosis burden >2.74 % of the LV mass…