Yonca Steubing
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Interdisciplinary therapy of extremity soft tissue sarcomas: current evidence on systemic treatments and the role of reconstructive surgery Open
Objectives Soft tissue sarcomas are rare and heterogenous tumors, that often pose diagnostic and therapeutic challenges. Guideline-compliant therapy includes surgical resection with negative margins, supplementary radiotherapy and, if nece…
Hypoxia-driven metastatic progression in synovial sarcoma: insights from SYO-1 and SW982 models Open
Background Synovial sarcoma (SS) is a rare but aggressive soft tissue malignancy characterized by a high rate of pulmonary metastasis and limited response to conventional therapies. Hypoxia, a common feature of tumor microenvironment, has …
Establishing a new rat model to investigate pathophysiology and bone healing in posttraumatic lymphedema Open
Introduction Posttraumatic lymphedema is a common complication after open and closed fractures with soft tissue trauma. Even though there is quite certain consensus about the basic mechanisms of lymphedema formation, the pathophysiology on…
Social Media Exposure and Muscle Dysmorphia Risk in Young German Athletes: A Cross-Sectional Survey with Machine-Learning Insights Using the MDDI-1 Open
Background and Objectives: Excessive social media use is repeatedly linked to negative body image outcomes, yet its association with muscle dysmorphia, especially in athletic youth, remains underexplored. We investigated how social media e…
Explosion-Related Polytrauma from Illicit Pyrotechnics: Two Case Reports and a Public Health Perspective Open
Firework-related injuries remain a serious public health issue in Germany, especially during New Year’s Eve. While many injuries are minor, the misuse of illegal or homemade fireworks can cause severe trauma resembling military combat inju…
Implementation of a CAM Assay Using Fibrosarcoma Spheroids Open
Fibrosarcomas represent a rare but highly aggressive tumor entity among soft tissue tumors. Due to its rarity, questions regarding its development and pathophysiology remain unclear. The chorioallantoic membrane (CAM) assay represents an e…
Metallosis after Motec metal-on-PEEK wrist replacement: A case report Open
Despite its increasing popularity, total wrist arthroplasty (TWA) remains a treatment option that is often viewed critically and is still rarely used in patients with partial or complete osteoarthritis of the wrist. TWA is an appropriate a…
Surgical Management of Septic Arthritis of the Wrist: An Analysis of Short- and Long-Term Functional and Clinical Outcomes Open
Septic arthritis of the wrist is a rare but severe condition requiring urgent diagnosis and treatment to prevent joint destruction and functional impairment. The objective of this study was to investigate prognostic parameters and the long…
View article: Generation Z in Plastic Surgery: Challenges, Solutions and New Horizons – A European and transatlantic overview
Generation Z in Plastic Surgery: Challenges, Solutions and New Horizons – A European and transatlantic overview Open
Introduction The entrance of Generation Z (born 1997–2012) into professional life, including the practice of medicine, marks a transformational shift in priorities and values. This generation, shaped by digital immersion and a strong focus…
Characteristics, Outcomes, and Risk Factors in Primary and Secondary Angiosarcoma: A Retrospective Cohort Study Open
Background Angiosarcomas (ASs) are a heterogeneous subtype of soft tissue sarcomas. They can be subdivided into primary and secondary AS, with secondary AS being predominant, particularly those following radiotherapy. The aim of this study…
View article: Risk Stratification with Sarculator and MSKCC in Patients with Primary and Secondary Angiosarcoma
Risk Stratification with Sarculator and MSKCC in Patients with Primary and Secondary Angiosarcoma Open
Background: Sarculator and Memorial Sloan Kettering Cancer Center (MSKCC) nomograms are freely available risk prediction scores for surgically treated patients with primary sarcomas. Due to the rarity of angiosarcomas, these scores have on…