Yong Hyun Jang
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View article: Effects of Inhaling the Cypress Essential Oil Complex on the Nasal Microbiome
Effects of Inhaling the Cypress Essential Oil Complex on the Nasal Microbiome Open
Background: Aromatherapy using natural essential oils has been proposed as a complementary strategy to prevent respiratory infections, particularly in elderly populations vulnerable to microbial colonization and antibiotic resistance. Obje…
View article: Inflammation dynamics of atopic dermatitis: Phase transition and scaling law of remission time
Inflammation dynamics of atopic dermatitis: Phase transition and scaling law of remission time Open
Atopic dermatitis (AD) is a prevalent skin disorder affecting individuals globally, with many patients experiencing a range of symptoms. A pronounced clinical phenomenon associated with AD is the cyclic alternation of two distinct phases i…
View article: Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part II): Biologics and JAK inhibitors
Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part II): Biologics and JAK inhibitors Open
KADA's updated AD treatment guidelines incorporate the latest evidence and expert opinion to provide a comprehensive approach to AD treatment. The guidelines will help clinicians optimize patient-specific therapies.
View article: Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): Basic Therapy, Topical Therapy, and Conventional Systemic Therapy
Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): Basic Therapy, Topical Therapy, and Conventional Systemic Therapy Open
KADA's updated AD guidelines offer clinicians evidence-based strategies focused on basic therapies, topical therapies, and conventional systemic therapies, equipping them to enhance quality of care and improve patient outcomes in AD manage…
View article: Comparative Efficacy of Ustekinumab and Guselkumab in Improving Itch in Severe Psoriasis Patients
Comparative Efficacy of Ustekinumab and Guselkumab in Improving Itch in Severe Psoriasis Patients Open
While guselkumab is generally preferred for psoriatic skin lesions, ustekinumab may provide superior itch relief.
View article: A Study on Scratching Behavior Characteristics in Patients With Various Types of Chronic Pruritus
A Study on Scratching Behavior Characteristics in Patients With Various Types of Chronic Pruritus Open
We analyzed scratching behavior patterns in patients with chronic pruritus. Our findings support the need for education on the importance of applying moisturizer before sleep. The results are also important for helping patients with prurig…
View article: Unraveling the Pathogenesis of Asian Atopic Dermatitis: Key Characteristics and Insights
Unraveling the Pathogenesis of Asian Atopic Dermatitis: Key Characteristics and Insights Open
Atopic dermatitis (AD) is a chronic skin condition influenced by genetic, environmental, and immune factors, with notable ethnic variations in its prevalence and mechanisms. In Asian populations, distinct immunopathogenic features include …
View article: Cutaneous Manifestations of COVID-19 Vaccinationand COVID-19 Infection: a Questionnaire-based,Multi-center Study in Korea
Cutaneous Manifestations of COVID-19 Vaccinationand COVID-19 Infection: a Questionnaire-based,Multi-center Study in Korea Open
Background: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause various cutaneous complications, including dermatologic adverse reactions to SARS-CoV-2 vaccines reported by several studies. Objective: To d…
View article: 2023 Consensus Korean Diagnostic Criteria for Atopic Dermatitis
2023 Consensus Korean Diagnostic Criteria for Atopic Dermatitis Open
This study streamlined and updated the diagnostic criteria for AD in Korea, making them more practicable for use in real-world clinical field.
View article: Long-Term Use of Oral Corticosteroids and Safety Outcomes for Patients With Atopic Dermatitis
Long-Term Use of Oral Corticosteroids and Safety Outcomes for Patients With Atopic Dermatitis Open
Importance The use of oral corticosteroids for prolonged periods may be associated with adverse events (AEs). Nevertheless, the risk of AEs with oral corticosteroids, especially among patients with atopic dermatitis (AD), has not been comp…
View article: Ethanol Extract of Ampelopsis brevipedunculata Rhizomes Suppresses IgE-Mediated Mast Cell Activation and Anaphylaxis
Ethanol Extract of Ampelopsis brevipedunculata Rhizomes Suppresses IgE-Mediated Mast Cell Activation and Anaphylaxis Open
More than 20% of the world’s population suffers from allergic diseases, including allergic asthma, rhinitis, and atopic dermatitis that severely reduce the patient’s quality of life. The treatment of allergy has been developed, but there a…
View article: Korean Consensus Criteria for the Severity Classification of Alopecia Areata
Korean Consensus Criteria for the Severity Classification of Alopecia Areata Open
These consensus criteria can help clinicians accurately diagnose AA, provide appropriate treatment, and monitor its progression.
View article: Factors Affecting the Response and Patient Satisfaction of Topical Immunotherapy in Alopecia Areata: A Nationwide Study
Factors Affecting the Response and Patient Satisfaction of Topical Immunotherapy in Alopecia Areata: A Nationwide Study Open
DPCP immunotherapy is an effective treatment for AA, and the study demonstrated the factors affecting DPCP treatment response and patients' satisfaction and may contribute to standardizing the DPCP treatment method for better outcomes.
View article: Survey on Alopecia Areata Patients’ Reported Factors that Determine Severity of Alopecia Areata: A Nationwide Multicenter Study
Survey on Alopecia Areata Patients’ Reported Factors that Determine Severity of Alopecia Areata: A Nationwide Multicenter Study Open
This survey underscores the significant impact of AA on patients' quality of life and highlights existing unmet needs in current treatment modalities.
View article: Herpes Zoster Granulomatous Dermatitis: A Rare but Memorable Complication
Herpes Zoster Granulomatous Dermatitis: A Rare but Memorable Complication Open
There have been reports of benign and cancerous cutaneous reactions developing at the site of resolved herpes zoster weeks to years after the acute infection. This case study describes a 71-year-old male patient with herpes zoster granulom…
View article: Interferon‐γ‐inducible protein 10 augments atopic dermatitis via amplifying Th2 immune response
Interferon‐γ‐inducible protein 10 augments atopic dermatitis via amplifying Th2 immune response Open
To the Editor Interferon-γ-inducible protein 10 (IP-10; CXCL10) is a T-helper 1 (Th1)-associated chemokine.1 However, IP-10 can reportedly be involved in Th2-mediated inflammation in allergic asthma,2 and elevated levels in the lesions and…
View article: Candidal Granuloma on the Lip Masquerading asSquamous Cell Carcinoma
Candidal Granuloma on the Lip Masquerading asSquamous Cell Carcinoma Open
Skin fungal infections are sometimes misdiagnosed as malignancies and vice versa. Herein, we present the case of a 78-year-old woman who visited our clinic because of a rapidly growing "hard-crusted nodule" on the lower lip persisting for …
View article: Survival rates for invasive cutaneous malignant melanoma in South Korea in accordance with the Eighth edition AJCC Cancer Staging Manual: A retrospective single center study
Survival rates for invasive cutaneous malignant melanoma in South Korea in accordance with the Eighth edition AJCC Cancer Staging Manual: A retrospective single center study Open
Background Cutaneous malignant melanoma is known to have a poorer prognosis in Asian patients as compared to Caucasians. Few studies have analysed the overall survival rate (OS) and melanoma-specific survival rate (MSS) of patients with cu…
View article: Lupeol alleviates atopic dermatitis-like skin inflammation in 2,4-dinitrochlorobenzene/Dermatophagoides farinae extract-induced mice
Lupeol alleviates atopic dermatitis-like skin inflammation in 2,4-dinitrochlorobenzene/Dermatophagoides farinae extract-induced mice Open
Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects from children to adults widely, presenting symptoms such as pruritus, erythema, scaling, and dryness. Lupeol, a pentacyclic triterpenoid, has anti-inflam…
View article: Management of Steroid-Induced Glaucoma in a Patient with Pyoderma Gangrenosum
Management of Steroid-Induced Glaucoma in a Patient with Pyoderma Gangrenosum Open
Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder typically presenting as painful skin ulcers, which may also exhibit extracutaneous findings. PG can occur at the site of trauma or surgery, which is known as the pathergic…
View article: Controlled Single Freezing Cryotherapy for Mild Facial Actinic Keratosis
Controlled Single Freezing Cryotherapy for Mild Facial Actinic Keratosis Open
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View article: Clinical Examination of Stenotrophomonas maltophiliaInfection in Patient with Pyoderma Gangrenosum
Clinical Examination of Stenotrophomonas maltophiliaInfection in Patient with Pyoderma Gangrenosum Open
View article: Dermatophagoides farinae Extract Induces Interleukin 33-Mediated Atopic Skin Inflammation via Activation of RIP1
Dermatophagoides farinae Extract Induces Interleukin 33-Mediated Atopic Skin Inflammation via Activation of RIP1 Open
Receptor-interacting protein kinase (RIP) family 1 signaling has complex effects on inflammatory processes and cell death, but little is known concerning allergic skin diseases. We examined the role of RIP1 in Dermatophagoides farinae extr…
View article: Cutaneous adverse drug reactions
Cutaneous adverse drug reactions Open
Background: Cutaneous adverse drug reactions are common and produce easily identifiable clinical symptoms. These may range from mild maculopapular rashes to severe reactions associated with systemic disease.Current Concepts: The most commo…
View article: Guidelines for the Management of Patients with Alopecia Areata in Korea: Part II Systemic Treatment
Guidelines for the Management of Patients with Alopecia Areata in Korea: Part II Systemic Treatment Open
The present study produced up-to-date, evidence-based treatment guidelines for AA associated with the consensus obtained by experts based on the Korean healthcare system.
View article: Erratum: Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea
Erratum: Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea Open
This corrects the article on p. 419 in vol. 34, PMID: 36478424.
View article: Effect of COVID-19 (SARS-CoV-2) Vaccination on Patients with Atopic Dermatitis Treated with Dupilumab: A Multicenter, Observational Study
Effect of COVID-19 (SARS-CoV-2) Vaccination on Patients with Atopic Dermatitis Treated with Dupilumab: A Multicenter, Observational Study Open
No serious adverse reactions were observed in patients with AD after COVID-19 vaccination. Exacerbation of pruritus and AD symptoms was observed but was mostly mild and transient.
View article: Guidelines for the Management of Patients with Alopecia Areata in Korea: Part I Topical and Device-based Treatment
Guidelines for the Management of Patients with Alopecia Areata in Korea: Part I Topical and Device-based Treatment Open
The present study provides up-to-date, evidence-based treatment guidelines for AA based on the consensus reached among experts after considering regional healthcare circumstances, adding diversity to the previous guidelines.
View article: Oleanolic Acid Acetate Inhibits Mast Cell Activation in Ovalbumin-Induced Allergic Airway Inflammation
Oleanolic Acid Acetate Inhibits Mast Cell Activation in Ovalbumin-Induced Allergic Airway Inflammation Open
Our study showed that OAA can inhibit mast cell-mediated allergic reaction. Consequently, the application of OAA to mast cells for the allergic airway inflammation facilitate a new direction of treating allergic asthma.
View article: Pemphigus Vulgaris in a Healthy Adult afterCOVID-19 Vaccination
Pemphigus Vulgaris in a Healthy Adult afterCOVID-19 Vaccination Open