Yong Huang
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View article: Application of pancreaticojejunostomy without suturing main pancreatic duct in laparoscopic pancreaticoduodenectomy for small main pancreatic duct (≤ 3 mm)
Application of pancreaticojejunostomy without suturing main pancreatic duct in laparoscopic pancreaticoduodenectomy for small main pancreatic duct (≤ 3 mm) Open
View article: Application experience of left hemihepatectomy using the left Glissonean pedicle transverse method combined with cholangiolithotomy via the anterior bile duct wall of the LHD to treat left hepatolithiasis
Application experience of left hemihepatectomy using the left Glissonean pedicle transverse method combined with cholangiolithotomy via the anterior bile duct wall of the LHD to treat left hepatolithiasis Open
View article: Simultaneous OCT A-scan depth ranging and C-scan volume imaging for intraoperative robotic retinal surgery guidance
Simultaneous OCT A-scan depth ranging and C-scan volume imaging for intraoperative robotic retinal surgery guidance Open
Current subretinal injection systems combine surgical microscopy, optical coherence tomography (OCT), and robotic assistance to enable precise, depth-resolved, and tremor-free drug delivery to targeted retinal sites. Nevertheless, subretin…
View article: BIOM-49. CLINICAL UTILITY OF CEREBROSPINAL FLUID CELL-FREE DNA MOLECULAR PROFILING AS A DIAGNOSTIC ADJUNCT IN REAL-WORLD NEURO-ONCOLOGY
BIOM-49. CLINICAL UTILITY OF CEREBROSPINAL FLUID CELL-FREE DNA MOLECULAR PROFILING AS A DIAGNOSTIC ADJUNCT IN REAL-WORLD NEURO-ONCOLOGY Open
Cerebrospinal fluid (CSF) cell-free DNA (cfDNA) is under evaluation as a liquid biopsy tool across multiple neuro-oncologic indications, including diagnosing lesions of uncertain etiology, delineating progression from pseudoprogression, an…
View article: The improvement of pancreatic duct stent tube in internal drainage during pancreaticojejunostomy—surgical technique
The improvement of pancreatic duct stent tube in internal drainage during pancreaticojejunostomy—surgical technique Open
The success of pancreaticojejunostomy (PJ) critically depends on achieving optimal pancreatic juice drainage. Clinical evidence demonstrates that internal stent placement is highly safe and effective in reducing postoperative complications…
View article: Effects of Three Aerobic Exercise Protocols on Acute Glucose Response and Continuous Glucose Monitoring Trends in Patients with Type 2 Diabetes Mellitus and Stroke: A Randomized Controlled Trial
Effects of Three Aerobic Exercise Protocols on Acute Glucose Response and Continuous Glucose Monitoring Trends in Patients with Type 2 Diabetes Mellitus and Stroke: A Randomized Controlled Trial Open
Objective This study aims to assess the acute and chronic effects of three aerobic exercise protocols, namely, Moderate-Intensity Interval Training (MIIT), Low-to-Moderate Intensity Continuous Training (LMICT), and Reduced-Exertion High-In…
View article: Impact of diverse aerobic exercise plans on glycemic control, lipid levels, and functional activity in stroke patients with type 2 diabetes mellitus
Impact of diverse aerobic exercise plans on glycemic control, lipid levels, and functional activity in stroke patients with type 2 diabetes mellitus Open
Aims This study aimed to assess the effects of Low-to-Moderate Intensity Continuous Training (LMICT), Moderate-Intensity Interval Training (MIIT), and Reduced-Exertion High-Intensity Training (REHIT) on blood glucose regulation, functional…
View article: Establishing a nausea-free ward model to reduce chemotherapy-induced nausea and vomiting: A retrospective study
Establishing a nausea-free ward model to reduce chemotherapy-induced nausea and vomiting: A retrospective study Open
The objective of this study was to establish a nausea-free ward model and evaluate the effect of an intervention procedure guided by this model on chemotherapy-induced nausea and vomiting (CINV) in cancer patients. A total of 105 chemother…
View article: The safety and feasibility of laparoscopic anatomical left hemihepatectomy along the middle hepatic vein from the head side approach
The safety and feasibility of laparoscopic anatomical left hemihepatectomy along the middle hepatic vein from the head side approach Open
Background Laparoscopic left hemihepatectomy (LLH) is commonly used for benign and malignant left liver lesions. We compared the benefits and drawbacks of LLH from the head side approach (LLHH) with those of conventional laparoscopic left …
View article: Nanocluster-antibody-drug conjugates (NADC) as an intravesical precision theranostic agent for interstitial cystitis
Nanocluster-antibody-drug conjugates (NADC) as an intravesical precision theranostic agent for interstitial cystitis Open
Interstitial cystitis (IC) is a chronic inflammatory bladder disorder with recurring severe pain, lacking timely diagnostic and therapeutic options. Here, we propose a unitary theranostic nanocluster-antibody-drug conjugate (NADC) by coval…
View article: Primary bone solitary B-cell lymphoblastic lymphoma aberrant expression Fli-1 and ERG: A case report
Primary bone solitary B-cell lymphoblastic lymphoma aberrant expression Fli-1 and ERG: A case report Open
Primary non-Hodgkin bone lymphoma is a rare disease, and within this category, B-cell lymphoblastic lymphoma (B-LBL) is an even rare clinical entity that has only been reported in small case series or individual case reports. B-LBL can mim…
View article: Comparing triple scope-combined bile duct exploration lithotripsy with laparoscopic hepatectomy for hepatolithiasis (with video)
Comparing triple scope-combined bile duct exploration lithotripsy with laparoscopic hepatectomy for hepatolithiasis (with video) Open
TS is a safe and effective treatment for HL and is superior to LH in terms of overall treatment outcome and complications.
View article: Combining Network Pharmacology, Pharmacokinetic-Pharmacodynamic Modeling and Metabolomics to Identify Active Components of Shuganning Injection and the Mechanism for Alleviation of Acute Liver Injury
Combining Network Pharmacology, Pharmacokinetic-Pharmacodynamic Modeling and Metabolomics to Identify Active Components of Shuganning Injection and the Mechanism for Alleviation of Acute Liver Injury Open
View article: Combining Network Pharmacology, Pharmacokinetic-Pharmacodynamic Modeling and Metabolomics to Reveal the Mechanism of Shuganning Injection in Alleviating Acute Liver Injury
Combining Network Pharmacology, Pharmacokinetic-Pharmacodynamic Modeling and Metabolomics to Reveal the Mechanism of Shuganning Injection in Alleviating Acute Liver Injury Open
View article: Efficacy and safety of patient-controlled epidural analgesia versus patient-controlled intravenous analgesia following open hepatectomy: A single-center retrospective study
Efficacy and safety of patient-controlled epidural analgesia versus patient-controlled intravenous analgesia following open hepatectomy: A single-center retrospective study Open
In patients undergoing open hepatectomy, PCEA was more effective than PCIA in relieving moderate to severe pain on POD1. However, improving the safety and effectiveness of PCEA remains a challenge.
View article: Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation
Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation Open
Interstitial cystitis/bladder pain syndrome (IC/BPS) seriously reduces the patient’s quality of life, yet current therapies only provide partial relief. In the spinal dorsal horn (SDH), neuroinflammation plays a pivotal role in the develop…
View article: Preservation versus resection of Denonvilliers’ fascia in total mesorectal excision for male rectal cancer: follow-up analysis of the randomized PUF-01 trial
Preservation versus resection of Denonvilliers’ fascia in total mesorectal excision for male rectal cancer: follow-up analysis of the randomized PUF-01 trial Open
Traditional total mesorectal excision (TME) for rectal cancer requires partial resection of Denonvilliers’ fascia (DVF), which leads to injury of pelvic autonomic nerve and postoperative urogenital dysfunction. It is still unclear whether …
View article: Resistin targets TAZ to promote osteogenic differentiation through PI3K/AKT/mTOR pathway
Resistin targets TAZ to promote osteogenic differentiation through PI3K/AKT/mTOR pathway Open
Osteogenic differentiation (OD) of bone marrow mesenchymal stem cells (BMSCs) contributes significantly to the regeneration of bone defects. Resistin, an adipose tissue-specific secretory factor, has been shown to involve many different fu…
View article: Comparative analysis of postoperative curative effect of liver wedge resection and liver IVb + V segment resection in patients with T2b gallbladder cancer
Comparative analysis of postoperative curative effect of liver wedge resection and liver IVb + V segment resection in patients with T2b gallbladder cancer Open
Objective To compare the therapeutic effects of wedge resection and liver segment IVb + V resection on patients with T2b gallbladder cancer. Methods The clinical and pathological data of 40 patients with gallbladder cancer admitted to the …
View article: Application experience of left hemihepatectomy with left glissonian pedicle transverse method combined cholangiolithotomy via anterior bile duct wall to treat left Hepatolithiasis
Application experience of left hemihepatectomy with left glissonian pedicle transverse method combined cholangiolithotomy via anterior bile duct wall to treat left Hepatolithiasis Open
Objective. To investigate the clinical significance of left hemihepatectomy with left glissonian pedicle transverse method combined cholangiolithotomy via anterior bile duct wall to treat left hepatolithiasis. Methods. A retrospective anal…
View article: Laparoscopic distal pancreatectomy may be an ideal surgical method for benign tumors in the pancreatic neck
Laparoscopic distal pancreatectomy may be an ideal surgical method for benign tumors in the pancreatic neck Open
Aims The two surgical methods that can remove pancreatic neck lesions are laparoscopic distal pancreatectomy (LDP) and laparoscopic central pancreatectomy (LCP). However, the benefits of the two surgical methods remain controversial. Metho…
View article: HO-1 alleviates neuroinflammation and cystitis-related symptoms in cyclophosphamide-induced cystitis via the SIRT1 pathway
HO-1 alleviates neuroinflammation and cystitis-related symptoms in cyclophosphamide-induced cystitis via the SIRT1 pathway Open
Background Our previous study suggested that astrocytes and microglia are activated in the spinal dorsal horn (SDH) of interstitial cystitis/bladder pain syndrome (IC/BPS) rats and induce neuroinflammation by secreting proinflammatory cyto…
View article: Intrathecal injection of human umbilical cord mesenchymal stem cells genetically engineered to overexpress Heme oxygenase 1 promotes symptoms recovery in cyclophosphamide-induced cystitis rats by alleviating neuroinflammation
Intrathecal injection of human umbilical cord mesenchymal stem cells genetically engineered to overexpress Heme oxygenase 1 promotes symptoms recovery in cyclophosphamide-induced cystitis rats by alleviating neuroinflammation Open
Background Interstitial cystitis/bladder pain syndrome (IC/BPS) seriously affect the patient's quality of life, yet current therapies for IC/BPS only provide partial relief. Neuroinflammation in the spinal dorsal horn (SDH) plays a pivotal…
View article: Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation Open
Background Neuroinflammation in spinal dorsal horn (SDH) plays an important role in the pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS). Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) exert potent anti-…
View article: Qi Sui Zhu Shui Plaster Inhibits AQP1 and MAPK Signaling Reduces Liver Damage Induced by Cirrhotic Ascites
Qi Sui Zhu Shui Plaster Inhibits AQP1 and MAPK Signaling Reduces Liver Damage Induced by Cirrhotic Ascites Open
Objective. At present, there is no special treatment for cirrhotic ascites in modern medicine. Qi Sui Zhu Shui plaster (QSZSP) has been used in ascites. The purpose of this study was to investigate the mechanism of action of QSZSP in the t…
View article: Urine- and Blood-Based Molecular Profiling of Human Prostate Cancer
Urine- and Blood-Based Molecular Profiling of Human Prostate Cancer Open
Objective Prostate cancer (PCa) is one of the most common malignant tumors, accounting for 20% of total tumors ranked first in males. PCa is usually asymptomatic at the early stage and the specificity of the current biomarkers for the dete…
View article: Circulating Cell-Free DNA-Based Detection of Tumor Suppressor Gene Copy Number Loss and Its Clinical Implication in Metastatic Prostate Cancer
Circulating Cell-Free DNA-Based Detection of Tumor Suppressor Gene Copy Number Loss and Its Clinical Implication in Metastatic Prostate Cancer Open
Current liquid biopsy assays lack sufficient sensitivity to detect copy number loss, which limits the interrogation of critical tumor suppressor gene deletions during cancer progression and treatment. Here we describe a liquid biopsy assay…
View article: Integrating Constituents Absorbed into Blood, Network Pharmacology, and Quantitative Analysis to Reveal the Active Components in Rubus chingii var. suavissimus that Regulate Lipid Metabolism Disorder
Integrating Constituents Absorbed into Blood, Network Pharmacology, and Quantitative Analysis to Reveal the Active Components in Rubus chingii var. suavissimus that Regulate Lipid Metabolism Disorder Open
Rubus chingii var. suavissimus (S. K. Lee) L. T. Lu (RS)—a sweet plant also known as Tiancha distributed in the south of China where it is used as a beverage—recently gained extensive attention as adjuvant therapy of diabetes and hypertens…
View article: Safety and feasibility of laparoscopic left hepatectomy for the treatment of hepatolithiasis in patients with previous abdominal surgery
Safety and feasibility of laparoscopic left hepatectomy for the treatment of hepatolithiasis in patients with previous abdominal surgery Open
Background: The aim of the study was to compare the benefits and drawbacks of laparoscopic left hepatectomy (LLH) in patients with previous abdominal surgery (PAS) with those in patients without PAS and confirm the safety and feasibility o…
View article: Alcohol Consumption and Tryptophan Metabolism Among People with HIV Prior to Antiretroviral Therapy Initiation: The Uganda ARCH Cohort Study
Alcohol Consumption and Tryptophan Metabolism Among People with HIV Prior to Antiretroviral Therapy Initiation: The Uganda ARCH Cohort Study Open
Aims Alcohol is hypothesized to have effects on the kynurenine pathway of tryptophan catabolism, a potential mechanism for alcohol-induced depression and aggression. A biomarker of this pathway, the plasma kynurenine to tryptophan ratio (K…