Yong Cui
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View article: Quantitative analysis of bone cement dispersion height in percutaneous vertebroplasty and kyphoplasty and comparison of therapeutic effects
Quantitative analysis of bone cement dispersion height in percutaneous vertebroplasty and kyphoplasty and comparison of therapeutic effects Open
Both PVP and PKP can significantly improve pain and other symptoms and improve the prognosis of patients with osteoporotic vertebral compression fracture.The PVP procedure has significant advantages in terms of operation time, frequency of…
View article: Integrated Multi‐Omics and Experimental Validation Unveil the GZMK/NF‐κB Axis Driving Inflammation and Fibroblast Proliferation in Rosacea: A Novel Drug Target Selection Strategy
Integrated Multi‐Omics and Experimental Validation Unveil the GZMK/NF‐κB Axis Driving Inflammation and Fibroblast Proliferation in Rosacea: A Novel Drug Target Selection Strategy Open
The prevalence of rosacea is high, while the drug options remain limited. Mendelian randomization (MR) is an effective way to prioritize plasma proteins as novel drug targets based on their causal effects on rosacea. The plasma proteins we…
View article: Efficacy and safety of secukinumab in Chinese patients with psoriasis: Update of six-year real-world data and a meta-analysis
Efficacy and safety of secukinumab in Chinese patients with psoriasis: Update of six-year real-world data and a meta-analysis Open
View article: Entropy-driven multi agent deep reinforcement learning for resilient distribution networks: coordinating MESS and microgrids
Entropy-driven multi agent deep reinforcement learning for resilient distribution networks: coordinating MESS and microgrids Open
In extreme disasters where severe main grid failures lead to widespread power outages in distribution networks, rapid critical load restoration (CLR) becomes crucial for enhancing power supply reliability. Aiming to improve distribution ne…
View article: Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment
Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment Open
PURPOSE: Alopecia Areata (AA) is an inflammatory non-cicatricial alopecia with a high prevalence. Some patients with AA show an inferior response to treatment. To find key proteins in AA, Genome-wide association study data from three cohor…
View article: Strategizing data compliance in intelligent healthcare: A four-step solution
Strategizing data compliance in intelligent healthcare: A four-step solution Open
View article: Deciphering the causal relationship between atopic dermatitis and lymphoma via multi-omics Mendelian randomization and colocalization analyses
Deciphering the causal relationship between atopic dermatitis and lymphoma via multi-omics Mendelian randomization and colocalization analyses Open
View article: Divergent and convergent evolution underlie the cocoon-spinning diversity
Divergent and convergent evolution underlie the cocoon-spinning diversity Open
Silk production and use are widespread and highly diversified in insects, yet the evolution and molecular bases underlying this diversity remain enigmatic. The Bombycoidea insects consist of sublineages that spin large cocoons (silk lineag…
View article: The deconstruction of the psoriasis system based on the theory of state‐target differentiation and treatment
The deconstruction of the psoriasis system based on the theory of state‐target differentiation and treatment Open
Psoriasis is a chronic, inflammatory skin condition characterized by its recurrent nature, often accompanied by various systemic comorbidities. It may not fully satisfy the precise diagnostic and therapeutic demands for psoriasis by the th…
View article: Reflectance Confocal Microscopy and Dermoscopic Imaging Features in Extramammary Paget’s Disease: A Retrospective Study
Reflectance Confocal Microscopy and Dermoscopic Imaging Features in Extramammary Paget’s Disease: A Retrospective Study Open
Objective: Extramammary Paget’s disease (EMPD) is often misdiagnosed as chronic dermatitis or eczema of the scrotum because of its clinical manifestations, leading to delayed diagnosis and treatment. Reflectance confocal microscopy (RCM) a…
View article: Dual‐Action Psoriasis Therapy: Antiproliferative and Immunomodulatory Effects via Self‐Locking Microneedles
Dual‐Action Psoriasis Therapy: Antiproliferative and Immunomodulatory Effects via Self‐Locking Microneedles Open
Psoriasis is a chronic, immune‐mediated disorder characterized by immune regulation disorders and abnormal keratinocyte proliferation. Deucravacitinib (Deu), a selective oral Tyrosine Kinase 2 (TYK2) inhibitor, shows promise in treating ps…
View article: Commentator Discussion: An innovative minimally invasive approach for hypertrophic obstructive cardiomyopathy: Transaortic septal myectomy via right infra-axillary incision
Commentator Discussion: An innovative minimally invasive approach for hypertrophic obstructive cardiomyopathy: Transaortic septal myectomy via right infra-axillary incision Open
View article: An innovative minimally invasive approach for hypertrophic obstructive cardiomyopathy: Transaortic septal myectomy via right infra-axillary incision
An innovative minimally invasive approach for hypertrophic obstructive cardiomyopathy: Transaortic septal myectomy via right infra-axillary incision Open
The transaortic modified Morrow procedure, performed through a minimally invasive right infra-axillary incision, shows favorable short-term outcomes.
View article: Selective attention function impairment in HIV-negative patients with early forms of neurosyphilis
Selective attention function impairment in HIV-negative patients with early forms of neurosyphilis Open
The orienting and alerting functions but not executive function were significantly less efficient in early forms of NS group than in the Non-NS group (P < 0.01). This indicates deficits in selective attention in patients with early forms o…
View article: SPATS2L is a positive feedback regulator of the type I interferon signaling pathway and plays a vital role in lupus
SPATS2L is a positive feedback regulator of the type I interferon signaling pathway and plays a vital role in lupus Open
Through genome-wide association studies (GWAS) and integrated expression quantitative trait locus (eQTL) analyses, numerous susceptibility genes ("eGenes", whose expressions are significantly associated with common variants) associated wit…
View article: Genetic prediction of the causal relationship between systemic lupus erythematosus and interstitial lung disease: a two-sample Mendelian randomized study
Genetic prediction of the causal relationship between systemic lupus erythematosus and interstitial lung disease: a two-sample Mendelian randomized study Open
Background Systemic lupus erythematosus (SLE) and interstitial lung disease (ILD) are often associated with clinical practice, and their co-pathogenesis and clinical features have been reported. However, genetic causality between SLE and I…
View article: Investigating Propionibacterium acnes antibiotic susceptibility and response to bacteriophage in vitro and in vivo
Investigating Propionibacterium acnes antibiotic susceptibility and response to bacteriophage in vitro and in vivo Open
Introduction A total of 94 Propionibacterium acnes ( P. acnes ) isolates were obtained from a hospital in Beijing to evaluate their susceptibility to erythromycin, clarithromycin, doxycycline, and minocycline. As well as the determination …
View article: Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese
Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese Open
View article: Adalimumab-Induced Erythrodermic Psoriasis Associated with Alopecia in a Patient with Palmoplantar Pustulosis
Adalimumab-Induced Erythrodermic Psoriasis Associated with Alopecia in a Patient with Palmoplantar Pustulosis Open
In recent years, with the increased usage of tumour necrosis factor (TNF) inhibitors, more side effects have been revealed. Paradoxical psoriasis, including psoriasis vulgaris, palmoplantar pustulosis, scalp psoriasis and their combination…
View article: Epigenetic regulation of H3K27me3 in laying hens with fatty liver hemorrhagic syndrome induced by high-energy and low-protein diets
Epigenetic regulation of H3K27me3 in laying hens with fatty liver hemorrhagic syndrome induced by high-energy and low-protein diets Open
Background： Fatty liver hemorrhagic syndrome (FLHS) in the modern poultry industry is primarily caused by nutrition. Despite encouraging progress on FLHS, the mechanism through which nutrition influences susceptibility to FLHS is still lac…
View article: Selective attention function impairment in HIV-negative patients with early forms of neurosyphilis
Selective attention function impairment in HIV-negative patients with early forms of neurosyphilis Open
Background: Attentional Network Test (ANT), was widely used to evaluate the performance of three attentional networks, i.e., alerting, orienting and executive attention networks. This study aimed to explore the characteristics of attention…
View article: Characterization of severe and critical COVID-19 infected individuals outside of Wuhan, China
Characterization of severe and critical COVID-19 infected individuals outside of Wuhan, China Open
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible among people，and the critical cases are still tough to treat, even leading to death. METHODS We retrospectively collected the clinical data of …
View article: At the beginning
At the beginning Open
Traditional Chinese Medicine (TCM) is an esteemed medical system that originated in China and has safeguarded the survival and prosperity of the Chinese nation for over three millennia. TCM stands not only as a cherished national treasure …
View article: Study on the mechanism of Cutaneous and Respiratory Comorbidities with Chinese and Western medicine theories and research
Study on the mechanism of Cutaneous and Respiratory Comorbidities with Chinese and Western medicine theories and research Open
In the realms of traditional Chinese medicine and Western medicine research, the skin and lungs are recognized for their integral roles in both the physiological functions and pathological mechanisms affecting the human body. These organs …
View article: Application of Cut-and-Sew Technique in Thoracoscopic Minimally Invasive Mitral Valve Surgery and Concomitant Maze Procedure
Application of Cut-and-Sew Technique in Thoracoscopic Minimally Invasive Mitral Valve Surgery and Concomitant Maze Procedure Open
The minimally invasive cut-and-sew technique for electrical isolation of left pulmonary veins can improve sinus conversion rate of patients suffering from both mitral valve disease and atrial fibrillation. In selected subjects, it is safe …
View article: Non-invasive imaging of pathological scars using a portable handheld two-photon microscope
Non-invasive imaging of pathological scars using a portable handheld two-photon microscope Open
Background: Pathological scars are a disorder that can lead to various cosmetic, psychological, and functional problems, and no effective assessment methods are currently available. Assessment and treatment of pathological scars are based …
View article: Submicron resolution techniques: Multiphoton microscopy in skin disease
Submicron resolution techniques: Multiphoton microscopy in skin disease Open
Non‐invasive optical examination plays a crucial role in various aspects of dermatology, such as diagnosis, management and research. Multiphoton microscopy uses a unique submicron technology to stimulate autofluorescence (AF), allowing for…
View article: Efficacy and safety of 1565‐nm nonablative fractional laser combined with mucopolysaccharide polysulfate cream for erythematous acne scars
Efficacy and safety of 1565‐nm nonablative fractional laser combined with mucopolysaccharide polysulfate cream for erythematous acne scars Open
Purpose To evaluate the efficacy and safety of 1565‐nm nonablative fractional laser (NAFL) combined with mucopolysaccharide polysulfate (MPS) cream in the treatment of erythematous acne scars. Methods A total of 28 subjects with erythemato…
View article: LSO-054 Genetic fine mapping of independent variants in MHC region associated with predisposition and clinical feature of systemic lupus erythematosus in Han Chinese population
LSO-054 Genetic fine mapping of independent variants in MHC region associated with predisposition and clinical feature of systemic lupus erythematosus in Han Chinese population Open
Background The association between major histocompatibility complex (MHC) regions and systemic lupus erythematosus (SLE) has been widely established. Methods To refined the most significant independent MHC loci with SLE susceptibility and …
View article: LO-036 Inhibition of transcolbalamin2 overexpression ameliorated renal injury in systemic lupus erythema via reducing pathogenic Tfh and B cell infiltration
LO-036 Inhibition of transcolbalamin2 overexpression ameliorated renal injury in systemic lupus erythema via reducing pathogenic Tfh and B cell infiltration Open
Background Transcolbalamin2 (TCN2) is a vitamin B12 transport plasma protein that facilitates cellular uptake of cobalamin. TCN2 deficiency displays a metabolic disorder with immunodeficiency disease. However, its functions in autoimmunity…