Explanipedia

Quality characteristics and printability of isolated soy protein subjected to physical and thermal treatments Open

Jin‐Won Kim, Yong-Sik Cho, Ha-Yun Kim, Kyung-Mi Kim, Hyeonbin Oh , et al. · 2025

CTRP3 exacerbates tendinopathy by dysregulating tendon stem cell differentiation and altering extracellular matrix composition Open

Yong-Sik Cho, Hyeon-Seop Kim, Donghyun Kang, Hyeonkyeong Kim, Narae Lee , et al. · 2021

Neutralization of CTRP3 opposes degenerative tendon matrix remodeling during tendinopathy.

Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions Open

Yong-Sik Cho, Su‐Min Jeong, Hyeonkyeong Kim, Donghyun Kang, Jeeyeon Lee , et al. · 2021

Suppression of Osteoarthritis progression by post-natal Induction of Nkx3.2 Open

Hye-Kyoung Oh, Minsun Park, Seung Won Choi, Daun Jeong, Byoung‐Ju Kim , et al. · 2021

Osteoarthritis (OA) is an incurable joint disease affecting 240 million elderly population, and major unmet medical needs exist for better therapeutic options for OA. During skeletal development, Nkx3.2 has been shown to promote chondrocyt…

Optimizing of Enzyme Hydrolysis Condition for Bitterness Suppression of Soybean Protein Using Response Surface Methodology (RSM) Open

Ha-Na Ra, Yong-Sik Cho, Young Hwang, Hyun-Wook Jang, Kyungmi Kim · 2020

Enzyme hydrolysis of soybean protein can be adjusted according to purposes, but should be optimized for reaction time, concentration and substrate conditions to prevent bitterness caused by excessive hydrolysis. This study was carried out …

A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression Open

Hyeonkyeong Kim, Yong-Sik Cho, Hyeon Seop Kim, Donghyun Kang, Donghyeon Cheon , et al. · 2020

Chondrosarcomas, malignant cartilaginous neoplasms, are capable of transitioning to highly aggressive, metastatic, and treatment-refractory states, resulting in significant patient mortality. Here, we aim to uncover the transcriptional pro…

Effect of Acidulant Treatment on the Quality and Storage Period of Topokkidduck Open

Ha-Na Ra, Yong-Sik Cho, Young Hwang, Hyun-Wook Jang, Kyung-Mi Kim · 2020

Quality Characteristics of Aronia Juice by Adding Water-Soluble Protein Open

Ji Hyun Park, Yong-Sik Cho, Young Hwang, Gyung Mee Gim, Hyun-Wook Jang , et al. · 2020

Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation Open

Sukyeong Kim, Sangbin Han, Yeongjae Kim, Hyeon-Seop Kim, Young-Ran Gu , et al. · 2019

Optimization of the Manufacturing Process for Mandarin Dry Chip Using Response Surface Methodology (RSM) Open

Ha-Na Ra, Ga-Yeong Park, Hayun Kim, Yong-Sik Cho, Kyung-Mi Kim · 2019

Optimization of the High-Pressure Condition for Rice Protein Extracting Using Response Surface Methodology (RSM) Open

Ha-Na Ra, Sa-Ra Park, Ha-Yun Kim, Yong-Sik Cho, Kyungmi Kim · 2019

Effects of Addition of Mixed Gelling Agent on Quality of Peach (Prunus persica L. Batsch) Jelly Open

Ga-Yeong Park, Ha-Na Ra, Yong-Sik Cho, Ha-Yun Kim, Kyungmi Kim · 2018

Change of quality properties of Doenjang according to soaking method in brine Open

Boyoung Choi, Na-Young Gil, Shin-Young Park, Yong-Sik Cho, So-Young Kim · 2017

This study was carried out to examine the quality characteristics of Doenjang manufactured with or without soaking Meju in brine according to salt concentrations (8 and 12%) during fermentation for 6 months. The moisture content and salini…

Physicochemical components of Cynanchi wilfordii Radix fermented with Rhizopus delemar Open

Bit-Na Song, Eunju Kim, Da-Som Jeong, So-Young Kim, Yong-Sik Cho , et al. · 2017

This study carried out to determine the physicochemical components of Cynanchi wilfordii Radix (CWR) fermented with Rhizopus delemar. The physicochemical components such as changes on moisture content, pH, total acidity, reducing sugars, a…

Physicochemical properties of Doenjang using grain type Meju fermented by Aspergillus oryzae and protease Open

Na-Young Gil, Boyoung Choi, Shin-Young Park, Yong-Sik Cho, So-Young Kim · 2017

The purpose of this study was to investigate the physiochemical properties of Doenjang was fermented by added with fungi and protease. The moisture content and pH of Doenjang added with protease (WP) were lower than those of control w/o pr…

비대칭 파봉선 길이에 따른 원형섬에서 고립파의 처오름높이 Open

조혜린, Yong-Sik Cho · 2017

우리나라 해안지역에는 많은 섬들이 위치하고 있어 대규모 지진해일이 발생하였을 때 섬과 지진해일의 상호작용으로 예기치 않은 지진해일 피해가 우려된다. 2011년 발생한 동일본 지진해일의 경우 제주도를 비롯한 남해안 섬들에 영향을 미쳤다. 본 연구에서는 천수이론에 근거한 수치모형을 이용하여 섬 중앙에 대하여 비대칭으로 입사하는 고립파의 처오름높이에 관하여 연구한다. 연구에서 얻은 결과는 지진해일의 급습에 대비한 방재대책을 수립하…

Distribution of Wave Forces at Points on a Vertical Structure of Semi-Infinite Breakwater Considering Diffraction Open

Jae-Sang Jung, Changhoon Lee, Yong-Sik Cho · 2016

본 연구에서는 회절을 고려하여 반무한방파제 형식의 직립구조물에 작용하는 지점별 파력 분포를 검토하였다. 비쇄파 조건에서 직립구조물에 작용하는 규칙파 및 불규칙파의 파력에 대해 방파제 전, 후면의 회절을 모두 고려하여 연구하였다. 방파제의 폭이 0인 조건을 비교 대상의 기준 조건으로 채택하였다. 규칙파의 경우 방파제 두부(head of breakwater)에서는 전후면의 입사파 및 회절파가 동시에 작용하여 상대 파력이 0이 되…

Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis Open

Yoonkyung Won, Youngnim Shin, Churl Hong Chun, Yong-Sik Cho, Chul‐Won Ha , et al. · 2016

MTs play an antiapoptotic role in post-traumatic OA. However, aberrant and chronic upregulation of MT2 triggers an imbalance between chondrocyte anabolism and catabolism, consequently accelerating OA development. Our findings collectively …

Three-dimensional Laboratory Experiments for Tsunami Force Coefficient at Imwon Port Open

Byung Ho Kim, Jae-Seon Yoon, Se Jong Han, Yong-Sik Cho · 2015

주로 갑작스러운 해저지진에 의해 발생하는 지진해일은 가장 파괴적인 자연재해 중의 하나이다. 지진해일은 진원지로부터 모든 방향으로 전파되며, 부근의 국가뿐만 아니라 멀리 떨어진 국가에도 피해를 일으킨다. 예를 들어, 1983년 5월 26일 일본의 서해안에서 발생한 동해중부 지진해일은 동해를 가로질러 우리나라의 동해안에도 피해를 일으켰다. 지진해일은 임원항에서 3명의 인명피해와 막대한 재산피해를 초래하였다. 따라서 지진해일에 의…

Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis Open

Hyeonkyeong Kim, Donghyun Kang, Yong-Sik Cho, Jin‐Hong Kim · 2015

Osteoarthritis (OA) is one of the most prevalent forms of joint disorder, associated with a tremendous socioeconomic burden worldwide. Various non-genetic and lifestyle-related factors such as aging and obesity have been recognized as majo…

Shear Current Effects on Monochromatic Water Waves Crossing Trenches Open

Jun‐Whan Lee, Koo-Yong Park, Yong-Sik Cho · 2015

The reflection coefficients of monochromatic water waves over trenches with shear current are estimated analytically. The diffraction of waves by an abrupt depth change and shear current is formulated by the matched eigenfunction expansion…

Numerical Simulation of Wind-Driven Circulation in a Thermally Stratified Flow Open

Jin Woo Lee, He-Rin Cho, Yong-Sik Cho · 2015

The closed water bodies, such as reservoirs and lakes, can be polluted by an inflow of pollutants in the upstream as well as a stratification caused by seasonal natural phenomena. The vertical circulation particularly plays an important ro…

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