Explanipedia

Clinical significance of regions of homozygosity detection in prenatal chromosomal microarray analysis Open

Ying Hao, Geng Qian, Xing‐Ping Li, Yang Jingxin, Yang Liu , et al. · 2025

Chromosomal microarray analysis (CMA) detects pathogenic copy-number variants (pCNVs) and regions of homozygosity (ROHs) in prenatal genetic analysis. This study evaluates the clinical significance of ROH detection in prenatal settings. We…

The memory-dependent FPK equation for fractional Gaussian noise Open

Lifang Feng, Bin Pei, Yong Xu · 2025

This paper aims to explore non-Markovian dynamics of nonlinear dynamical systems subjected to fractional Gaussian noise (FGN) and Gaussian white noise (GWN). A novel memory-dependent Fokker-Planck-Kolmogorov (memFPK) equation is developed …

Synchronization transitions and spike dynamics in a higher-order Kuramoto model with Lévy noise Open

Dan Zhao, Jürgen Kurths, Norbert Marwan, Yong Xu · 2025

Synchronization in various complex networks is significantly influenced by higher-order interactions combined with non-Gaussian stochastic perturbations, yet their mechanisms remain mainly unclear. In this paper, we systematically investig…

The relationship between the triglyceride to high-density lipoprotein cholesterol ratio and positive blood or pus cultures in patients with pyogenic liver abscess Open

Qian Huang, Zixuan Huang, Haiyan Lin, Yong Xu, Xiaoxu Xie , et al. · 2025

The TG/HDL-C ratio demonstrates a nonlinear relationship with the risk of positive blood or pus cultures in patients with PLA, with a pivotal threshold value identified at 9.2. This readily obtainable ratio may help clinicians individualiz…

Graph neural network-based drug-drug interaction prediction Open

Khushnood Abbas, Hao Chen, Yong Xu, Mohammad Kamrul Hasan, Shayla Islam , et al. · 2025

With the growing variety of pharmacological compounds and the increasing need for polypharmacy, accurately predicting drug-drug interactions (DDIs) is essential to ensure both treatment efficacy and patient safety. Beneficial DDIs can enha…

Alternative escape for run-and-tumble particles from a potential with spatially random perturbations Open

Yongge Li, R.J. Zhang, Xinwei Zheng, Yong Xu, Yongqiang Liu · 2025

The dynamics of self-propelled particles are naturally affected by both spatial and temporal perturbations due to the disordered landscapes and thermal fluctuations in their living environment. Here, we investigate the escape properties of…

Flutter Suppression Enhancement in Coupled Nonlinear Airfoils with Intermittent Mixed Interactions Open

Qi Liu, Riccardo Muolo, Hiroya Nakao, Yong Xu · 2025

Flutter suppression facilitates the improvement of structural reliability to ensure the flight safety of an aircraft. In this study, we propose a novel strategy for enlarging amplitude death (AD) regime to enhance flutter suppression in tw…

Transition path properties of a run and tumble particle subjected to an external potential Open

H. B. Li, Yong Xu, Ralf Metzler, Z. Wang, Kheder Suleiman · 2025

Run-and-tumble particle (RTP) motion is a key model for certain bacteria and other actively moving microscopic particles, combining phases of directed motion with ‘tumbles’, stationary phases during which the particle reorients itself. We …

The pseudo-analytical density solution to parameterized Fokker-Planck equations via deep learning Open

Xiaolong Wang, Jing Feng, Gege Wang, Tong Li, Yong Xu · 2025

Efficiently solving the Fokker-Planck equation (FPE) is crucial for understanding the probabilistic evolution of stochastic particles in dynamical systems, however, analytical solutions or density functions are only attainable in specific …

Data-based nonlinear and stochastic dynamics Open

Yong Xu, Jürgen Kurths, Yongge Li, Stefano Lenci · 2025

Dynamic Responses of Flexible Wing Panels With Random Loads Open

Yong Xu, Qi Liu · 2025

Personal Wellbeing Amid Pandemic Response: Impacts of Neighborhood Built Environment, Risk Communication and Health Open

Chunlan Guo, Kit Fai Wong, Yong Xu, Kevin Kei Ching Hung, Hung Chak Ho · 2024

Maintaining personal wellbeing is essential for an effective pandemic response due to its multifaceted impacts on various aspects of society. This study aimed to evaluate personal wellbeing during pandemic response and investigate the effe…

Averaging principle for semilinear slow-fast rough partial differential equations Open

Miaomiao Li, Yunzhang Li, Bin Pei, Yong Xu · 2024

In this paper, we investigate the averaging principle for a class of semilinear slow-fast partial differential equations driven by finite-dimensional rough multiplicative noise. Specifically, the slow component is driven by a general rando…

Large deviation principle for slow-fast systems with infinite-dimensional mixed fractional Brownian motion Open

Weishuang Xu, Yong Xu, Xiaoyu Yang, Bin Pei · 2024

This work is concerned with the large deviation principle for a family of slow-fast systems perturbed by infinite-dimensional mixed fractional Brownian motion with Hurst parameter $H\in(\frac12,1)$. We adopt the weak convergence method whi…

Complex dynamics of a magnetic microrobot driven by single deformation soft tail in random environment Open

Xinpeng Shi, Yongge Li, Yong Xu, Qi Liu · 2024

This study focuses on exploring the complex dynamical behaviors of a magnetic microrobot in a random environment. The purpose is to reveal the mechanism of influence of random disturbance on microrobot dynamics. This paper establishes stoc…

AlphaFin: Benchmarking Financial Analysis with Retrieval-Augmented Stock-Chain Framework Open

Xiang Li, Zhenyu Li, Shi Chen, Yong Xu, Qing Du , et al. · 2024

The task of financial analysis primarily encompasses two key areas: stock trend prediction and the corresponding financial question answering. Currently, machine learning and deep learning algorithms (ML&DL) have been widely applied for st…

Dynamical Behaviours of the Nose Landing Gear with Freeplay and Stochastic Disturbance Open

Xingbin Du, Yong Xu · 2024

Shimmy dynamics of a dual wheel nose landing gear system with torsional freeplay under stochastic lateral disturbances is studied. Dynamic characteristics of the deterministic case are numerically analyzed, especially the shimmy of the lan…

Enhanced fault diagnosis via stochastic resonance in a piecewise asymmetric bistable system Open

Yongge Li, Qisheng Zhu, Yong Xu, Ruilan Tian · 2024

Weak fault signals are often overwhelmed by strong noise or interference. The key issue in fault diagnosis is to accurately extract useful fault characteristics. Stochastic resonance is an important signal processing method that utilizes n…

Moderate deviations for two-time scale systems with mixed fractional Brownian motion Open

Xiaoyu Yang, Yuzuru Inahama, Yong Xu · 2023

This work focuses on moderate deviations for two-time scale systems with mixed fractional Brownian motion. Our proof uses the weak convergence method which is based on the variational representation formula for mixed fractional Brownian mo…

Almost Sure Averaging for Fast-slow Stochastic Differential Equations via Controlled Rough Path Open

Bin Pei, Robert Hesse, Bjoern Schmalfuss, Yong Xu · 2023

This paper establishes the averaging method to a coupled system consisting of two stochastic differential equations which has a slow component driven by fractional Brownian motion (FBM) with less regularity $1/3< H \leq 1/2$ and a fast dyn…

Almost Sure Averaging for Evolution Equations driven by fractional Brownian motions Open

Bin Pei, Bjoern Schmalfuss, Yong Xu · 2023

We apply the averaging method to a coupled system consisting of two evolution equations which has a slow component driven by fractional Brownian motion (FBM) with the Hurst parameter $H_1> \frac12$ and a fast component driven by additive F…

Advance on stochastic dynamics/nonlinear and stochastic dynamics Open

Yong Xu, Yongge Li, Stefano Lenci · 2023

Global dynamics of a dengue fever model incorporating transmission seasonality Open

Min Zhu, Tingting Feng, Yong Xu, Jinde Cao · 2023

The changes of seasons cause that the transmission of dengue fever is characterized by periodicity. We develop a dengue fever transmission model incorporating seasonal periodicity and spatial heterogeneity. Based on the well-posedness of s…

Safety and efficacy of esketamine for postoperative analgesia in pediatric patients with hypospadias Open

Yong Xu, Quan Chen, Ping Li, Xingrong Song · 2023

Objective To explore the safety and efficacy of the combination of continuous intravenous infusion of esketamine with sacral block for postoperative analgesia in pediatric patients undergoing surgery for hypospadias Methods Pediatric patie…

Supplementary Methods, Tables 1-4, Figures 1-4 from SKLB1206, a Novel Orally Available Multikinase Inhibitor Targeting EGFR Activating and T790M Mutants, ErbB2, ErbB4, and VEGFR2, Displays Potent Antitumor Activity Both <i>In Vitro</i> and <i>In Vivo</i> Open

Youli Pan, Yong Xu, Feng Shan, Shidong Luo, Renlin Zheng , et al. · 2023

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Supplemental Figure S1 from RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells Open

Xiaowei Wei, Yong Xu, Fang Fang Xu, Luksana Chaiswing, David Schnell , et al. · 2023

The effect of PEG-CAT on radiosensitization of AA in PC3 cells was determined by MTT assay.

supplemental tables and figures from Scavenger Receptor A1 Prevents Metastasis of Non–Small Cell Lung Cancer via Suppression of Macrophage Serum Amyloid A1 Open

Yan Zhang, Yongyue Wei, Bin Jiang, Lili Chen, Hui Bai , et al. · 2023

table S1-3,population data;Fig S1,SR-A1 deficiency exacerbates LLC metastasis;Fig S2, signal pathways in LLC cells;Fig S3,macrophage migration assay;Fig S4,qRT-PCR data.

Supplemental Table S1 from RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells Open

Xiaowei Wei, Yong Xu, Fang Fang Xu, Luksana Chaiswing, David Schnell , et al. · 2023

Mutually exclusive CIs for the AA-IR combined treatment for PC3 cells and PZ cells at indicated doses.

Data from RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells Open

Xiaowei Wei, Yong Xu, Fang Fang Xu, Luksana Chaiswing, David Schnell , et al. · 2023

Cancer cells typically experience higher oxidative stress than normal cells, such that elevating pro-oxidant levels can trigger cancer cell death. Although pre-exposure to mild oxidative agents will sensitize cancer cells to radiation, thi…

Supplemental Figure S2 from RelB Expression Determines the Differential Effects of Ascorbic Acid in Normal and Cancer Cells Open

Xiaowei Wei, Yong Xu, Fang Xu, Luksana Chaiswing, David Schnell , et al. · 2023

After treatment with AA, the expression of RelB, Bcl-xL, and Bax in PC3 and PZ cells was quantified by western blots by RT-PCR.

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