Yongbin Lu
YOU?
Author Swipe
View article: Propylparaben Promotes Estrogen Receptor-Positive Breast Cancer Risk through PIK3R1: A Comprehensive Integrative Study
Propylparaben Promotes Estrogen Receptor-Positive Breast Cancer Risk through PIK3R1: A Comprehensive Integrative Study Open
Background Propylparaben (PP), a preservative in cosmetics, food, and pharmaceuticals, is a potential endocrine disruptor. However, the molecular mechanisms linking PP exposure to estrogen receptor-positive (ER⁺) breast cancer (BC) remain …
View article: KLF5 facilitates lung adenocarcinoma metastasis by regulating the epithelial-mesenchymal transition pathway through RHPN2
KLF5 facilitates lung adenocarcinoma metastasis by regulating the epithelial-mesenchymal transition pathway through RHPN2 Open
View article: Synergistic effects of cadmium exposure and hypertension on all-cause and cardiovascular mortality in individuals with prediabetes
Synergistic effects of cadmium exposure and hypertension on all-cause and cardiovascular mortality in individuals with prediabetes Open
Environmental factors play a critical role in the pathogenesis of abnormal blood glucose and its complications. However, research on the relationship between environmental factors, blood glucose, and mortality is limited. Using NHANES (199…
View article: Environmental cadmium exposure promotes lung cancer via DHX34: A molecular toxicology perspective
Environmental cadmium exposure promotes lung cancer via DHX34: A molecular toxicology perspective Open
Although cadmium (Cd) exposure has been implicated in lung cancer development, systematic investigations into its association with cancer mortality, particularly lung cancer mortality remain limited, and the molecular mechanisms driving Cd…
View article: KLF5 facilitates lung adenocarcinoma metastasis via regulating the epithelial-mesenchymal transition pathway through RHPN2
KLF5 facilitates lung adenocarcinoma metastasis via regulating the epithelial-mesenchymal transition pathway through RHPN2 Open
Background Distant metastasis is the primary reason shortening the survival time for patients with advanced lung adenocarcinoma. Transcription factor Kruppel-like factor 5 (KLF5) has been confirmed to facilitate the progression of lung ade…
View article: Comparative Effectiveness of Paclitaxel‐Containing Regimens for Treatment of Triple‐Negative Breast Cancer: A Network Meta‐Analysis
Comparative Effectiveness of Paclitaxel‐Containing Regimens for Treatment of Triple‐Negative Breast Cancer: A Network Meta‐Analysis Open
Objective To evaluate the efficacy and safety of paclitaxel‐based regimens, including traditional Chinese medicine (TCM) combinations, for the treatment of triple‐negative BC (TNBC) using a network meta‐analysis. Methods PubMed, EMBASE, Th…
View article: The impact of cadmium exposure on breast cancer risk: Exploring dose-response relationships and mediating effects
The impact of cadmium exposure on breast cancer risk: Exploring dose-response relationships and mediating effects Open
View article: Rnf5-Mediated Ubiquitination of Acsl4 Attenuates Ferroptosis and Confers Cardioprotection Against Myocardial Ischemia/Reperfusion Injury
Rnf5-Mediated Ubiquitination of Acsl4 Attenuates Ferroptosis and Confers Cardioprotection Against Myocardial Ischemia/Reperfusion Injury Open
View article: PVT1 acts as a molecular scaffold to mediate PPARγ transcription and promote macrophage reprogramming in triple-negative breast cancer
PVT1 acts as a molecular scaffold to mediate PPARγ transcription and promote macrophage reprogramming in triple-negative breast cancer Open
Objective The long non-coding RNA (lncRNA) PVT1 plays a significant role in regulating the development and progression of various cancers. However, its clinical relevance in triple-negative breast cancer (TNBC) and its immunoregulatory mec…
View article: Turning the Tables: Estradiol as a Protective Factor in Breast Cancer Risk - Findings from a NHANES-Based Study on Lead and Cadmium Exposure
Turning the Tables: Estradiol as a Protective Factor in Breast Cancer Risk - Findings from a NHANES-Based Study on Lead and Cadmium Exposure Open
View article: MYC/MAX-Activated LINC00958 Promotes Lung Adenocarcinoma by Oncogenic Transcriptional Reprogramming Through HOXA1 Activation
MYC/MAX-Activated LINC00958 Promotes Lung Adenocarcinoma by Oncogenic Transcriptional Reprogramming Through HOXA1 Activation Open
Background Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer. The role of the long non-coding RNA (lncRNA) LINC00958, which regulates the malignant behavior of multiple tumors, in LUAD has not been elucidate…
View article: TRIM65 Promotes Malignant Cell Behaviors in Triple‐Negative Breast Cancer by Impairing the Stability of LATS1 Protein
TRIM65 Promotes Malignant Cell Behaviors in Triple‐Negative Breast Cancer by Impairing the Stability of LATS1 Protein Open
TNBC is a malignant tumor that easily relapses and metastasizes, with a poor prognosis in women. Ubiquitination plays a key role in promoting the tumor process. In various tumors, TRIM65 can affect malignant biological tumor behavior by ub…
View article: Upregulated cyclins may be novel genes for triple-negative breast cancer based on bioinformatic analysis
Upregulated cyclins may be novel genes for triple-negative breast cancer based on bioinformatic analysis Open
Our results suggest that cyclin CDK1, CCNB1, and CCNA2 are overexpressed in TNBC and they could act as novel biomarkers for the diagnosis and treatment of TNBC.
View article: Effects of parity on the age at menopause and menopausal syndrome: a cross-sectional study in Northwest China
Effects of parity on the age at menopause and menopausal syndrome: a cross-sectional study in Northwest China Open
Objective This study evaluated the relationship between the number of births and the age at menopause and menopausal syndrome among Chinese women in Gansu. Methods A cross-sectional study was conducted by a local university from March to N…
View article: <p><em>EPS8</em> is a Potential Oncogene in Glioblastoma</p>
<em>EPS8</em> is a Potential Oncogene in Glioblastoma Open
EP8S plays a role in the development of GBM and may be a potential therapeutic target for GBM.
View article: Effectiveness of long-term using statins in COPD – a network meta-analysis
Effectiveness of long-term using statins in COPD – a network meta-analysis Open