Yufei Ma
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View article: Replacing cholesterol and PEGylated lipids with zwitterionic ionizable lipids in LNPs for spleen-specific mRNA translation
Replacing cholesterol and PEGylated lipids with zwitterionic ionizable lipids in LNPs for spleen-specific mRNA translation Open
The spleen is emerging as a key vaccination target. However, existing lipid nanoparticles (LNPs) primarily accumulate in the liver, limiting their efficacy in vaccine therapy. The cholesterol in current LNP formulations promotes their upta…
View article: InfoGain-RAG: Boosting Retrieval-Augmented Generation via Document Information Gain-based Reranking and Filtering
InfoGain-RAG: Boosting Retrieval-Augmented Generation via Document Information Gain-based Reranking and Filtering Open
Retrieval-Augmented Generation (RAG) has emerged as a promising approach to address key limitations of Large Language Models (LLMs), such as hallucination, outdated knowledge, and lacking reference. However, current RAG frameworks often st…
View article: Engineering Study on Targeted Therapy of Osteosarcoma Using Tripterine Loaded Polydopamine Mesoporous Microspheres Combined with Photothermal Therapy
Engineering Study on Targeted Therapy of Osteosarcoma Using Tripterine Loaded Polydopamine Mesoporous Microspheres Combined with Photothermal Therapy Open
MPDA-PEG-CLT significantly enhances celastrol's targeted delivery efficiency, promotes mitochondrial apoptosis in osteosarcoma cells, synergizes with photothermal therapy to eradicate tumors, and improves the bone tissue microenvironment i…
View article: An ultra-highly sensitive LITES sensor based on multi-pass cell with ultra-dense spot pattern designed by multi-objective algorithm
An ultra-highly sensitive LITES sensor based on multi-pass cell with ultra-dense spot pattern designed by multi-objective algorithm Open
Multi-pass cell (MPC) with long optical path length (OPL) and high ratio of optical path length to volume (RLV) can significantly enhance the detection performance of light-induced thermoelastic spectroscopy (LITES) sensor and facilitate s…
View article: Robust CH<sub>4</sub>-TDLAS sensor based on state-switching adaptive Kalman filtering
Robust CH<sub>4</sub>-TDLAS sensor based on state-switching adaptive Kalman filtering Open
Tunable diode laser absorption spectroscopy (TDLAS) is a highly advantageous technique for trace gas detection, characterized by its low cost, high precision, and compact design. However, in complex field environments, external disturbance…
View article: All-Fiber LITES Sensor Based on Hollow-Core Anti-Resonant Fiber and Self-Designed Low-Frequency Quartz Tuning Fork
All-Fiber LITES Sensor Based on Hollow-Core Anti-Resonant Fiber and Self-Designed Low-Frequency Quartz Tuning Fork Open
In this paper, an all-fiber light-induced thermoelastic spectroscopy (LITES) sensor based on hollow-core anti-resonant fiber (HC-ARF) and self-designed low-frequency quartz tuning fork (QTF) is reported for the first time. By utilizing HC-…
View article: Parts-per-quadrillion level gas molecule detection: CO-LITES sensing
Parts-per-quadrillion level gas molecule detection: CO-LITES sensing Open
Highly sensitive gas detection plays a crucial role in advanced scientific and technological fields. This paper presents a parts-per-quadrillion (ppq) level ultra-highly sensitive light-induced thermoelectric spectroscopy (LITES) sensor fo…
View article: LITES-Based Sensitive CO2 Detection Using 2 μm Diode Laser and Self-Designed 9.5 kHz Quartz Tuning Fork
LITES-Based Sensitive CO2 Detection Using 2 μm Diode Laser and Self-Designed 9.5 kHz Quartz Tuning Fork Open
A carbon dioxide (CO2) sensor based on light-induced thermoelastic spectroscopy (LITES) using a 2 μm diode laser and a self-designed low-frequency trapezoidal-head QTF is reported for the first time in this invited paper. The self-designed…
View article: Load capacitance matching for resonant frequency adjusting-based multi-quartz tuning fork-enhanced laser spectroscopic sensing
Load capacitance matching for resonant frequency adjusting-based multi-quartz tuning fork-enhanced laser spectroscopic sensing Open
What we believe to be a novel load capacitance matching method is proposed for adjusting the resonant frequency of a quartz tuning fork (QTF) in a multi-QTF-based laser spectroscopy gas sensor for the first time. A sensing system integrati…
View article: Highly sensitive H2S-LITES sensor with 80 m fiber-coupled multi-pass cell based on optical path multiplexing technology
Highly sensitive H2S-LITES sensor with 80 m fiber-coupled multi-pass cell based on optical path multiplexing technology Open
This paper presented a highly sensitive light-induced thermoelastic spectroscopy (LITES) sensor for detecting hydrogen sulfide (H₂S) gas. Optical path multiplexing (OPM) technology was implemented within the fiber-coupled multi-pass cell (…
View article: A Highly Sensitive Light-Induced Thermoelastic Spectroscopy Sensor Using a Charge Amplifier to Improve the Signal-to-Noise Ratio
A Highly Sensitive Light-Induced Thermoelastic Spectroscopy Sensor Using a Charge Amplifier to Improve the Signal-to-Noise Ratio Open
A highly sensitive light-induced thermoelastic spectroscopy (LITES) sensor employing a charge amplifier (CA) is reported for the first time in this invited paper. CA has the merits of high input impedance and strong anti-interference abili…
View article: A Highly Sensitive TDLAS-Based Water Vapor Isotopes Sensor Using a Quantum Cascade Laser
A Highly Sensitive TDLAS-Based Water Vapor Isotopes Sensor Using a Quantum Cascade Laser Open
Based on tunable diode laser absorption spectroscopy (TDLAS), a water isotopes detection system was developed to detect the isotopic abundance of water vapor in the atmosphere. A single 1483.79 cm−1 quantum cascade laser (QCL) and a 3120 c…
View article: A high sensitive methane QEPAS sensor based on self-designed trapezoidal-head quartz tuning fork and high power diode laser
A high sensitive methane QEPAS sensor based on self-designed trapezoidal-head quartz tuning fork and high power diode laser Open
A high sensitive methane (CH4) sensor based on quartz-enhanced photoacoustic spectroscopy (QEPAS) using self-designed trapezoidal-head quartz tuning fork (QTF) and high power diode laser is reported for the first time in this paper. The tr…
View article: Highly sensitive laser spectroscopy sensing based on a novel four-prong quartz tuning fork
Highly sensitive laser spectroscopy sensing based on a novel four-prong quartz tuning fork Open
In this paper, a novel four-prong quartz tuning fork (QTF) was designed with enlarged deformation area, large prong gap, and low resonant frequency to improve its performance in laser spectroscopy sensing. A theoretical simulation model wa…
View article: Highly Sensitive T-Shaped Quartz Tuning Fork Based CH4-Light-Induced Thermoelastic Spectroscopy Sensor with Hydrogen and Helium Enhanced Technique
Highly Sensitive T-Shaped Quartz Tuning Fork Based CH4-Light-Induced Thermoelastic Spectroscopy Sensor with Hydrogen and Helium Enhanced Technique Open
In this paper, a highly sensitive methane (CH4) sensor based on light-induced thermoelastic spectroscopy (LITES) and a T-shaped quartz tuning fork (QTF) with hydrogen (H2) and helium (He) enhancement techniques are reported for the first t…
View article: Design of multipass cell with dense spot patterns and its performance in a light-induced thermoelastic spectroscopy-based methane sensor
Design of multipass cell with dense spot patterns and its performance in a light-induced thermoelastic spectroscopy-based methane sensor Open
In this study, a ray tracing model based on the law of reflection in vector form was developed to obtain the design parameters of multipass cells (MPC) with dense spot patterns. Four MPCs with distinct patterns were obtained using an estab…
View article: Highly sensitive CH<sub>4,</sub>C<sub>2</sub>H<sub>2</sub>and CO simultaneous measurement LITES sensor based on multi-pass cell with overlapped spots pattern and QTFs with low resonant frequency
Highly sensitive CH<sub>4,</sub>C<sub>2</sub>H<sub>2</sub>and CO simultaneous measurement LITES sensor based on multi-pass cell with overlapped spots pattern and QTFs with low resonant frequency Open
This paper presents a simultaneous measurement light-induced thermoelectric spectroscopy (LITES) sensor with high sensitivity for detecting methane (CH 4 ), carbon monoxide (CO) and acetylene (C 2 H 2 ). It employs a multi-pass cell (MPC) …
View article: Design and Fabrication of Quartz MEMS Based Double-ended Tuning Fork Resonator
Design and Fabrication of Quartz MEMS Based Double-ended Tuning Fork Resonator Open
This paper presents the design and fabrication of double-ended tuning fork (DETF) resonator based on quartz. DETF resonator was designed with two tines structure, due to this configuration has the advantage of providing dynamic balance. Bo…