Yong‐cheng Hu
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View article: Temperature-based protection of biochemical and biomechanical characteristics during 25 kGy 60Co irradiation for allograft tendons
Temperature-based protection of biochemical and biomechanical characteristics during 25 kGy 60Co irradiation for allograft tendons Open
Deep cryogenic preservation (-70 °C) demonstrates enhanced protective effects over conventional refrigeration for γ-irradiated tendon allografts, suggesting temperature optimization as critical in clinical processing protocols.
View article: Exploring the asynchronous changes of articular cartilage and osteochondral junction in knee osteoarthritis based on T2 mapping and ultrashort echo time imaging: a pilot study
Exploring the asynchronous changes of articular cartilage and osteochondral junction in knee osteoarthritis based on T2 mapping and ultrashort echo time imaging: a pilot study Open
The T2 and UTE-T2* values, respectively, provide quantitative and non-invasive measures of the degeneration in the AC and the OCJ during the early stages of KOA. Quantitative MRI biomarkers reveal biochemical alterations in both the AC and…
View article: Design and Practical Application of a Waveform Cryogenic Clamp: Innovation in Low-temperature Control and Tendon Biomechanics
Design and Practical Application of a Waveform Cryogenic Clamp: Innovation in Low-temperature Control and Tendon Biomechanics Open
This study innovatively developed a waveform cryogenic clamp to address issues like insufficient low - temperature maintenance, slippage, and structural damage in connective tissue biomechanical testing. The cooling efficiency of the clamp…
View article: U-shaped kirschner wire transfixation: effective treatment for Skier’s thumb
U-shaped kirschner wire transfixation: effective treatment for Skier’s thumb Open
Background Skier’s thumb is a type of injury to the ulnar collateral ligament of the metacarpophalangeal joint of the thumb, which can result in bone fragmentation and joint instability. Objective The objective of this study was to compare…
View article: Modular intercalary prosthetic reconstruction for malignant and metastatic tumours of the proximal femur
Modular intercalary prosthetic reconstruction for malignant and metastatic tumours of the proximal femur Open
To illustrate the surgical technique and explore clinical outcomes of the reconstruction for the malignant and metastatic bone tumour of proximal femur with metallic modular intercalary prosthesis. Sixteen patients who underwent modular in…
View article: Temperature-based protection of biochemical and biomechanical characteristics during 25 kGy 60Co irradiation for allograft tendons
Temperature-based protection of biochemical and biomechanical characteristics during 25 kGy 60Co irradiation for allograft tendons Open
Background: Nowadays, there is a lack of effective treatment for reducing damage to the collagen proteins in tendons during the gamma irradiation process. We aim to investigate different temperatures on the protection of allogeneic tendons…
View article: Can the Sterilization Protocol Be Improved to Enhance the Healing of Allograft Tendons? An In Vivo Study in Rabbit Tendons
Can the Sterilization Protocol Be Improved to Enhance the Healing of Allograft Tendons? An In Vivo Study in Rabbit Tendons Open
Background Peracetic acid and irradiation are common sterilization methods for allograft tendons; however, under some conditions, both methods adversely affect the fiber arrangement and ultimate load of the tendon. An in vitro study showed…
View article: Limitations and modifications in the clinical application of calcium sulfate
Limitations and modifications in the clinical application of calcium sulfate Open
Calcium sulfate and calcium sulfate-based biomaterials have been widely used in non-load-bearing bone defects for hundreds of years due to their superior biocompatibility, biodegradability, and non-toxicity. However, lower compressive stre…
View article: Microwave-induced hyperthermia in situ in the treatment of tumors of proximal humerus: long-term results with functionary sparing surgery
Microwave-induced hyperthermia in situ in the treatment of tumors of proximal humerus: long-term results with functionary sparing surgery Open
Background The present study aimed to evaluate the indications, feasibility, clinical effectiveness and complications of the treatment with microwave in situ inactivation followed by curettage and bone grafting assisted with internal fixat…
View article: Effect of decalcified RGD peptide-modified bone matrix on osteoblast differentiation
Effect of decalcified RGD peptide-modified bone matrix on osteoblast differentiation Open
View article: Pulmonary Function in Patients with Solitary Spinal Metastases: A Hospital-Based Cross-Sectional Study
Pulmonary Function in Patients with Solitary Spinal Metastases: A Hospital-Based Cross-Sectional Study Open
Thoracic vertebral metastasis was the main type of solitary spinal metastatic tumor. Spinal metastases were more common at ages 60-69 years. There was no significant difference in pulmonary function among patients with spinal metastasis at…
View article: Postoperative Functional Assessment in Patients with Tumors Around the Knee Treated with Endoprosthetic Reconstruction: A Multicenter Retrospective Cohort Study
Postoperative Functional Assessment in Patients with Tumors Around the Knee Treated with Endoprosthetic Reconstruction: A Multicenter Retrospective Cohort Study Open
Objectives The restoration of as much normal function as possible has become an important goal following the endoprosthetic reconstruction. The objective of this study was to assess the functional outcome after endoprosthetic reconstructio…
View article: Clinical guidelines for microwave ablation of spinal metastases
Clinical guidelines for microwave ablation of spinal metastases Open
Spinal metastases are the most common source of morbidity in patients with cancer. Recently, microwave ablation has produced satisfactory results in the management of spinal metastases. However, there is still controversy in terms of clini…
View article: Novel Three‐Holed Titanium Plate Fixation during Open Door Laminoplasty for Cervical Spondylotic Myelopathy: Comparison with Conventional Titanium Plate
Novel Three‐Holed Titanium Plate Fixation during Open Door Laminoplasty for Cervical Spondylotic Myelopathy: Comparison with Conventional Titanium Plate Open
Objective For reconstructing the posterior cervical muscular–ligament complex, attachment points and various modified techniques were designed and applied in clinical practice. This study investigated the clinical and radiographic outcomes…
View article: Effects of Chemical Sterilization and Gamma Irradiation on the Biochemical and Biomechanical Properties of Human Tendon Allografts In Vitro Study
Effects of Chemical Sterilization and Gamma Irradiation on the Biochemical and Biomechanical Properties of Human Tendon Allografts In Vitro Study Open
Objective Pre‐implantation sterilization procedures for tendons are important measures to reduce the risk of disease transmission, however these procedures may compromise tendon microarchitecture and biomechanical properties to varying deg…
View article: [Research progress of cementless intercalary prosthesis stem].
[Research progress of cementless intercalary prosthesis stem]. Open
Improving the design and fixation method of the cementless intercalary prosthesis stem can further improve the stability of the prosthesis. Under the premise of avoiding increasing surgical trauma as much as possible, addition of the auxil…
View article: Chinese Clinical Practice Guidelines in Treating Knee Osteoarthritis by Periarticular Knee Osteotomy
Chinese Clinical Practice Guidelines in Treating Knee Osteoarthritis by Periarticular Knee Osteotomy Open
Unicompartmental knee osteoarthritis (UKOA) is the early stage of knee joint degeneration, which is characterized by unicompartmental degeneration and mostly occurs in medial compartment. Pain and limited motion are main symptoms, which af…
View article: Prognostic Factors for Bone Survival and Functional Outcomes in Patients With Breast Cancer Spine Metastases
Prognostic Factors for Bone Survival and Functional Outcomes in Patients With Breast Cancer Spine Metastases Open
According to the Global Cancer Statistics 2020 report, breast cancer is the most commonly diagnosed cancer worldwide. Patients with mammary cancer live longer due to the continuous optimization of chemotherapy, targeted drugs, and hormone …
View article: Separation Surgery in the Treatment of Spinal Metastasis
Separation Surgery in the Treatment of Spinal Metastasis Open
The life expectancy of patients with advanced cancer has been prolonged with the development of systemic treatment technology. Spinal metastasis is one of the common ways of metastasis of advanced tumors, leading to spinal cord compression…
View article: Application of Controlled Hypotension During Surgery for Spinal Metastasis
Application of Controlled Hypotension During Surgery for Spinal Metastasis Open
With advances in tumor treatment, metastasis to bone is increasing, and surgery has become the only choice for most terminal patients. However, spinal surgery has a high risk and is prone to heavy bleeding. Controlled hypotension during su…
View article: Bisphosphonates May Reduce Intraoperative Blood Loss in Surgery for Metastatic Spinal Disease: A Retrospective Cohort Study
Bisphosphonates May Reduce Intraoperative Blood Loss in Surgery for Metastatic Spinal Disease: A Retrospective Cohort Study Open
We found that the preoperative use of bisphosphonates could reduce the amount of intraoperative blood loss during metastatic spinal tumor surgery, especially for surgery with longer operative time.
View article: Peracetic Acid‐Ethanol Processed Human Tendon Allograft: A Morphological, Biochemical, and Biomechanical Study <scp> <i>In Vitro</i> </scp>
Peracetic Acid‐Ethanol Processed Human Tendon Allograft: A Morphological, Biochemical, and Biomechanical Study <span> <i>In Vitro</i> </span> Open
PES treatment for 30 min has no adverse effect on the properties of human hamstring tendon allografts, longer processing time could not promise better properties preservation.
View article: A novel tool for predicting the survival of endoprosthesis used for reconstruction of the knee following tumor resection: a retrospective cohort study
A novel tool for predicting the survival of endoprosthesis used for reconstruction of the knee following tumor resection: a retrospective cohort study Open
View article: Comparison of Outcomes Following TiRobot-Assisted Sacroiliac Screw Fixation with Bone Grafting and Traditional Screw Fixation without Bone Grafting for Unstable Osteoporotic Sacral Fracture: A Single-Center Retrospective Study of 33 Patients
Comparison of Outcomes Following TiRobot-Assisted Sacroiliac Screw Fixation with Bone Grafting and Traditional Screw Fixation without Bone Grafting for Unstable Osteoporotic Sacral Fracture: A Single-Center Retrospective Study of 33 Patients Open
BACKGROUND This retrospective study from a single center aimed to compare patient outcomes following TiRobot-assisted sacroiliac screw fixation and bone grafting with traditional screw fixation without bone grafting in 33 patients with uns…
View article: Nomogram for Predicting the Postoperative Venous Thromboembolism in Spinal Metastasis Tumor: A Multicenter Retrospective Study
Nomogram for Predicting the Postoperative Venous Thromboembolism in Spinal Metastasis Tumor: A Multicenter Retrospective Study Open
Introduction Venous thromboembolism can be divided into deep vein thrombosis and pulmonary embolism. These diseases are a major factor affecting the clinical prognosis of patients and can lead to the death of these patients. Unfortunately,…
View article: Research Progress on Assessment of Blood Supply of Spinal Tumors and Methods of Reducing Intraoperative Blood Loss
Research Progress on Assessment of Blood Supply of Spinal Tumors and Methods of Reducing Intraoperative Blood Loss Open
In order to avoid the intra- and post-operative risks caused by massive blood loss, there are various clinical methods for evaluating the blood supply of the tumor and the distribution of blood vessels around the tumor before surgery, such…
View article: Influence of a metaphyseal sleeve on the stress-strain state of a bone-tumor implant system in the distal femur: an experimental and finite element analysis
Influence of a metaphyseal sleeve on the stress-strain state of a bone-tumor implant system in the distal femur: an experimental and finite element analysis Open
View article: Admission deep venous thrombosis of lower extremity after intertrochanteric fracture in the elderly: a retrospective cohort study
Admission deep venous thrombosis of lower extremity after intertrochanteric fracture in the elderly: a retrospective cohort study Open
Objective The purpose of this study was to investigate the incidence, location, and related factors of deep venous thrombosis (DVT) of the bilateral lower extremities after intertrochanteric fractures in the elderly. Methods Retrospective …
View article: Clinical Guideline for Microwave Ablation of Bone Tumors in Extremities
Clinical Guideline for Microwave Ablation of Bone Tumors in Extremities Open
Microwave ablation has been used to treat bone tumors in extremities for more than 30 years. With improved recognition, updated microwave equipment, and expanded clinical application, microwave ablation has recently been widely used to tre…
View article: Clinical factors affecting prognosis of limb osteosarcoma in China: a multicenter retrospective analysis
Clinical factors affecting prognosis of limb osteosarcoma in China: a multicenter retrospective analysis Open
Objective This study was performed to explore the relationship between various clinical factors and the prognosis of limb osteosarcoma. Methods We retrospectively analyzed the clinical data of 336 patients with limb osteosarcoma treated fr…