Yang Shu
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View article: CrossAD: Time Series Anomaly Detection with Cross-scale Associations and Cross-window Modeling
CrossAD: Time Series Anomaly Detection with Cross-scale Associations and Cross-window Modeling Open
Time series anomaly detection plays a crucial role in a wide range of real-world applications. Given that time series data can exhibit different patterns at different sampling granularities, multi-scale modeling has proven beneficial for u…
View article: The effect of negative emotions on smoking craving: the chain-mediating role of self-control and self-exempting beliefs
The effect of negative emotions on smoking craving: the chain-mediating role of self-control and self-exempting beliefs Open
Background Previous studies have demonstrated that negative emotions increase smoking cravings. To date, the specific action pathways between negative emotions and smoking cravings remain unclear. This study aimed to investigate the associ…
View article: Comparative validation of surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation in endoscopy: Results of the PhaKIR 2024 challenge
Comparative validation of surgical phase recognition, instrument keypoint estimation, and instrument instance segmentation in endoscopy: Results of the PhaKIR 2024 challenge Open
Reliable recognition and localization of surgical instruments in endoscopic video recordings are foundational for a wide range of applications in computer- and robot-assisted minimally invasive surgery (RAMIS), including surgical training,…
View article: Serum zinc as a biomarker to predict the efficacy of immune checkpoint inhibitors in cancers
Serum zinc as a biomarker to predict the efficacy of immune checkpoint inhibitors in cancers Open
Purpose The aim of this study was to investigate whether serum zinc levels correlate with the response to immune checkpoint inhibitors (ICIs) and whether they can be used as a useful prognostic biomarker in patients with advanced or metast…
View article: The pan genome analysis of <i>WOX</i> gene family in apple and the two sides of <i>MdWUS-1</i> in promoting leaf-borne shoot
The pan genome analysis of <i>WOX</i> gene family in apple and the two sides of <i>MdWUS-1</i> in promoting leaf-borne shoot Open
Unlike animals, plants are sessile organisms that cannot move freely in response to fluctuating and complex environments. As a result, plant development follows post-embryonic processes, enabling flexible developmental strategies to adapt …
View article: A single-cell RNA-seq dataset of synovial fluid from rheumatoid arthritis treated with TNF-α/JAK inhibitor
A single-cell RNA-seq dataset of synovial fluid from rheumatoid arthritis treated with TNF-α/JAK inhibitor Open
Although multiple single-cell RNA sequencing (scRNA-seq) based studies have explored rheumatoid arthritis (RA), most have focused on synovial tissue, limiting the ability to perform paired pre- and post-treatment comparisons and to elucida…
View article: Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury Open
Ferroptosis is a newly identified cell death triggered by iron‐induced lipid peroxidation. Numerous studies reveal that ferroptosis participates in multiple types of tissue injury including ischaemia–reperfusion (I/R) injury and doxorubici…
View article: Dominance of acetoclastic methanogenesis in municipal solid waste (MSW) decomposition despite high variability in microbial community composition: insights form natural stable carbon isotope and metagenomic analyses
Dominance of acetoclastic methanogenesis in municipal solid waste (MSW) decomposition despite high variability in microbial community composition: insights form natural stable carbon isotope and metagenomic analyses Open
View article: Single-cell transcriptomic analysis reveals gut microbiota-immunotherapy synergy through modulating tumor microenvironment
Single-cell transcriptomic analysis reveals gut microbiota-immunotherapy synergy through modulating tumor microenvironment Open
The gut microbiota crucially regulates the efficacy of immune checkpoint inhibitor (ICI) based immunotherapy, but the underlying mechanisms remain unclear at the single-cell resolution. Using single-cell RNA sequencing and subsequent valid…
View article: Why Reasoning Matters? A Survey of Advancements in Multimodal Reasoning (v1)
Why Reasoning Matters? A Survey of Advancements in Multimodal Reasoning (v1) Open
Reasoning is central to human intelligence, enabling structured problem-solving across diverse tasks. Recent advances in large language models (LLMs) have greatly enhanced their reasoning abilities in arithmetic, commonsense, and symbolic …
View article: Context Aware Multimodal Fusion YOLOv5 Framework for Pedestrian Detection under IoT Environment
Context Aware Multimodal Fusion YOLOv5 Framework for Pedestrian Detection under IoT Environment Open
Pedestrian detection based on deep networks has become a research hotspot in the field of computer vision. With the rapid development of the Internet of Things (IoT) and autonomous driving technology, the deployment of pedestrian detection…
View article: Learning Generalizable Skills from Offline Multi-Task Data for Multi-Agent Cooperation
Learning Generalizable Skills from Offline Multi-Task Data for Multi-Agent Cooperation Open
Learning cooperative multi-agent policy from offline multi-task data that can generalize to unseen tasks with varying numbers of agents and targets is an attractive problem in many scenarios. Although aggregating general behavior patterns …
View article: Comparison of machine learning and nomogram to predict 30-day in-hospital mortality in patients with acute myocardial infarction combined with cardiogenic shock: a retrospective study based on the eICU-CRD and MIMIC-IV databases
Comparison of machine learning and nomogram to predict 30-day in-hospital mortality in patients with acute myocardial infarction combined with cardiogenic shock: a retrospective study based on the eICU-CRD and MIMIC-IV databases Open
View article: Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment
Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment Open
View article: Natural-selected plastics biodegradation species and enzymes in landfills
Natural-selected plastics biodegradation species and enzymes in landfills Open
Biodegradation is a promising and environmentally friendly strategy for plastic pollution management. Landfills decompose municipal solid waste, including almost 50% of global plastic debris and even some of the oldest synthetic plastics, …
View article: The relationship between social support and smartphone addiction: the mediating role of negative emotions and self-control
The relationship between social support and smartphone addiction: the mediating role of negative emotions and self-control Open
Clinical trial number: not applicable.
View article: β-eudesmol inhibits cell growth and enhances cell chemosensitivity of NPC through targeting FGF1/FGFR signaling
β-eudesmol inhibits cell growth and enhances cell chemosensitivity of NPC through targeting FGF1/FGFR signaling Open
β-eudesmol suppressed cell growth, metastasis and chemoresistance in NPC through targetingFGF1/FGFR signaling, thereby blocking the Akt signaling, STAT3 signaling andERKsignaling, as well as down-regulating ABCC1 expression. Our findings p…
View article: The Application of the Enhanced Recovery after Surgery Concept in the Perioperative Management of Early Gastric Cancer Patients Undergoing Endoscopic Submucosal Dissection
The Application of the Enhanced Recovery after Surgery Concept in the Perioperative Management of Early Gastric Cancer Patients Undergoing Endoscopic Submucosal Dissection Open
View article: Response of methanogenesis to the local environment along a 2.0-km deep Quaternary Saline Lacustrine Source Rocks
Response of methanogenesis to the local environment along a 2.0-km deep Quaternary Saline Lacustrine Source Rocks Open
Biogenic gas in deep subsurface has gained significant attention as a clean and efficient energy source. Due to the challenges associated with sample extraction, knowledge regarding the methanogenesis mechanism in deep biogenic gas fields …
View article: Diagnostic value of methylated SEPT9 and RNF180 for gastric cancer in high-risk population: a multi-centre retrospective study in Yunnan, Southwest China
Diagnostic value of methylated SEPT9 and RNF180 for gastric cancer in high-risk population: a multi-centre retrospective study in Yunnan, Southwest China Open
View article: A dendritic cell vaccine for both vaccination and neoantigen-reactive T cell preparation for cancer immunotherapy in mice
A dendritic cell vaccine for both vaccination and neoantigen-reactive T cell preparation for cancer immunotherapy in mice Open
Adoptive cell transfer (ACT) using neoantigen-specific T cells is an effective immunotherapeutic strategy. However, the difficult isolation of neoantigen-specific T cells limits the clinical application of ACT. Here, we propose a method to…
View article: Generalizing Hyperedge Expansion for Hyper-relational Knowledge Graph Modeling
Generalizing Hyperedge Expansion for Hyper-relational Knowledge Graph Modeling Open
By representing knowledge in a primary triple associated with additional attribute-value qualifiers, hyper-relational knowledge graph (HKG) that generalizes triple-based knowledge graph (KG) has been attracting research attention recently.…
View article: MultiRC: Joint Learning for Time Series Anomaly Prediction and Detection with Multi-scale Reconstructive Contrast
MultiRC: Joint Learning for Time Series Anomaly Prediction and Detection with Multi-scale Reconstructive Contrast Open
Many methods have been proposed for unsupervised time series anomaly detection. Despite some progress, research on predicting future anomalies is still relatively scarce. Predicting anomalies is particularly challenging due to the diverse …
View article: The Role of long non‐coding RNA MEG3 in Cancer‐Associated Fibroblasts at Single Cell Pan‐cancer Level (4/2024)
The Role of long non‐coding RNA MEG3 in Cancer‐Associated Fibroblasts at Single Cell Pan‐cancer Level (4/2024) Open
View article: [<i>Pterocarya hupehensis</i> Skan total flavones ameliorate rheumatoid arthritis in rats by suppressing formation of neutrophil extracellular traps].
[<i>Pterocarya hupehensis</i> Skan total flavones ameliorate rheumatoid arthritis in rats by suppressing formation of neutrophil extracellular traps]. Open
PHSTF can alleviate RA by inhibiting the formation of NETs.
View article: The role of long non‐coding RNA Maternally Expressed Gene 3 in cancer‐associated fibroblasts at single cell pan‐cancer level
The role of long non‐coding RNA Maternally Expressed Gene 3 in cancer‐associated fibroblasts at single cell pan‐cancer level Open
Long non‐coding RNAs (lncRNAs) can crucially regulate activation and transformation of cancer‐associated fibroblasts (CAFs) but have not been systematically investigated at single cell resolution. Here, by utilizing integrated single‐cell …
View article: Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer Open
Magnesium (Mg) deficiency is associated with increased risk and malignancy in colorectal cancer (CRC), yet the underlying mechanisms remain elusive. Here, we used genomic, proteomic, and phosphoproteomic data to elucidate the impact of Mg …
View article: Species pool and soil properties in mangrove habitats influence the species-immigration process of diazotrophic communities across southern China
Species pool and soil properties in mangrove habitats influence the species-immigration process of diazotrophic communities across southern China Open
Microbial immigration is an ecological process in natural environments; however, the ecological trade-off mechanisms that govern the balance between species extinction and migration are still lacking. In this study, we investigated the mec…
View article: Development and Clinical Applications of Therapeutic Cancer Vaccines with Individualized and Shared Neoantigens
Development and Clinical Applications of Therapeutic Cancer Vaccines with Individualized and Shared Neoantigens Open
Neoantigens, presented as peptides on the surfaces of cancer cells, have recently been proposed as optimal targets for immunotherapy in clinical practice. The promising outcomes of neoantigen-based cancer vaccines have inspired enthusiasm …
View article: Symbiodiniaceae and Ruegeria sp. Co-Cultivation to Enhance Nutrient Exchanges in Coral Holobiont
Symbiodiniaceae and Ruegeria sp. Co-Cultivation to Enhance Nutrient Exchanges in Coral Holobiont Open
The symbiotic relationship between corals and their associated microorganisms is crucial for the health of coral reef eco-environmental systems. Recently, there has been a growing interest in unraveling how the manipulation of symbiont nut…