Yongfeng Shao
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View article: Nomogram predictive model for the incidence and risk factors of persistent fever after cardiovascular surgery
Nomogram predictive model for the incidence and risk factors of persistent fever after cardiovascular surgery Open
Background A persistent fever following cardiovascular surgery presents a significant clinical challenge and often leads to adverse patient outcomes. This study aims to develop a nomogram predictive model for persistent postoperative fever…
View article: NPAS2 attenuates VSMC phenotypic switching in ascending thoracic aortic aneurysm via LPCAT3/PC-PUFA2S-mediated ferroptosis
NPAS2 attenuates VSMC phenotypic switching in ascending thoracic aortic aneurysm via LPCAT3/PC-PUFA2S-mediated ferroptosis Open
Ascending thoracic aortic aneurysm (ATAA) is a life-threatening disorder with limited therapeutic options, critically linked to vascular smooth muscle cell (VSMC) phenotypic switching. Neuronal PAS Domain Protein 2 (NPAS2), a circadian rhy…
View article: Procalcitonin as a biomarker for postoperative pneumonia: a study on dynamics following cardiopulmonary bypass in adults
Procalcitonin as a biomarker for postoperative pneumonia: a study on dynamics following cardiopulmonary bypass in adults Open
View article: Incorporating Circulating Plasma Interleukin-10 Enhanced Risk Predictability of Mortality in Acute Type A Aortic Dissection Surgery
Incorporating Circulating Plasma Interleukin-10 Enhanced Risk Predictability of Mortality in Acute Type A Aortic Dissection Surgery Open
Background: Acute type A aortic dissection (TAAD) is a life-threatening cardiovascular emergency with a high mortality rate. The peri-operative factors influencing in-hospital mortality among surgically treated TAAD patients remain unclear…
View article: Efficacy and safety of the blood-based cardioplegia solution Huaxi-1 in cardiopulmonary bypass surgery: protocol for a multicentre randomised controlled trial
Efficacy and safety of the blood-based cardioplegia solution Huaxi-1 in cardiopulmonary bypass surgery: protocol for a multicentre randomised controlled trial Open
Introduction Cardioplegia during cardiopulmonary bypass is essential for ensuring a surgical field free of blood and cardiac movement. Numerous cardioplegia solutions are available, but consensus guidelines about the safest or most effecti…
View article: Comparison of clinical outcomes between double arterial cannulation and single arterial cannulation in type A aortic dissection
Comparison of clinical outcomes between double arterial cannulation and single arterial cannulation in type A aortic dissection Open
It remains controversial as to which optimal cannulation strategy ought to be employed in surgery for type A aortic dissection (TAAD). The aim of this study was to make a comparison of the clinical outcomes between single and double arteri…
View article: Protective effect of ulinastatin against negative inflammatory response and organ dysfunction in acute aortic dissection surgery: The PANDA trial
Protective effect of ulinastatin against negative inflammatory response and organ dysfunction in acute aortic dissection surgery: The PANDA trial Open
Ulinastatin is a protease-inhibiting drug with anti-inflammatory and other pharmacological properties. Little is known regarding its role following acute type A aortic dissection (ATAAD) surgery. We perform a randomized controlled trial to…
View article: In situ needle fenestration for aortic arch conditions during thoracic endovascular aortic repair
In situ needle fenestration for aortic arch conditions during thoracic endovascular aortic repair Open
The mid-term results of the ISNF technique during TEVAR for aortic arch conditions were within the acceptable range; however, further follow-up results are needed and long-term stability and durability needs to be assessed. Related fenestr…
View article: Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation
Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation Open
View article: A nomogram for predicting the risk of postoperative delirium in individuals undergoing cardiovascular surgery
A nomogram for predicting the risk of postoperative delirium in individuals undergoing cardiovascular surgery Open
Background and Purpose Delirium is a common mental disorder after adult cardiovascular surgery. Fifteen to 23% of patients undergoing cardiovascular surgery and cardiomyopathy experience delirium, and the efficacy of treatment intervention…
View article: Corrigendum to “MicroRNA-30c functions as a tumor suppressor via targeting SNAI1 in esophageal squamous cell carcinoma” [Biomed. Pharmacother. 98 (2018) 680–686]
Corrigendum to “MicroRNA-30c functions as a tumor suppressor via targeting SNAI1 in esophageal squamous cell carcinoma” [Biomed. Pharmacother. 98 (2018) 680–686] Open
View article: Inflammatory signature-based theranostics for acute lung injury in acute type A aortic dissection
Inflammatory signature-based theranostics for acute lung injury in acute type A aortic dissection Open
Acute lung injury (ALI) is a serious adverse event in the management of acute type A aortic dissection (ATAAD). Using a large-scale cohort, we applied artificial intelligence-driven approach to stratify patients with different outcomes and…
View article: miR-19a-3p enhances TGF-β1-induced cardiac fibroblast activation <i>via</i> targeting BAMBI
miR-19a-3p enhances TGF-β1-induced cardiac fibroblast activation <i>via</i> targeting BAMBI Open
Myocardial fibrosis is a major pathogenic factor contributing to cardiac remodeling and heart failure. Recent research has indicated that microRNAs play a crucial role in the progression of cardiac fibrosis. Bone morphogenetic protein and …
View article: Author Correction: Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification
Author Correction: Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification Open
View article: Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation
Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation Open
Macrophage activation is a hallmark of atherosclerosis, accompanied by a switch in core metabolism from oxidative phosphorylation to glycolysis. The crosstalk between metabolic rewiring and histone modifications in macrophages is worthy of…
View article: Operative Mortality After Type A Aortic Dissection Surgery
Operative Mortality After Type A Aortic Dissection Surgery Open
View article: ASF1A-dependent P300-mediated histone H3 lysine 18 lactylation promotes atherosclerosis by regulating EndMT
ASF1A-dependent P300-mediated histone H3 lysine 18 lactylation promotes atherosclerosis by regulating EndMT Open
Endothelial-to-mesenchymal transition (EndMT) is a key driver of atherosclerosis. Aerobic glycolysis is increased in the endothelium of atheroprone areas, accompanied by elevated lactate levels. Histone lactylation, mediated by lactate, ca…
View article: Chinese Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (5A) Registry protocol: rationale, design and methodology
Chinese Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (5A) Registry protocol: rationale, design and methodology Open
View article: A rare case of mitral valve dysplasia and left ventricular noncompaction: surgical management and genetic investigation
A rare case of mitral valve dysplasia and left ventricular noncompaction: surgical management and genetic investigation Open
View article: Anti-inflammatory response-based risk assessment in acute type A aortic dissection: A national multicenter cohort study
Anti-inflammatory response-based risk assessment in acute type A aortic dissection: A national multicenter cohort study Open
This risk model reflecting inflammatory, coagulation, and metabolic pathways achieved acceptable predictive performances of operative mortality following TAAD surgery, which will contribute to individualized anti-inflammatory pharmacothera…
View article: Postoperative thrombocytopenia and subsequent consequences in acute type A aortic dissection
Postoperative thrombocytopenia and subsequent consequences in acute type A aortic dissection Open
Early postoperative thrombocytopenia following type A aortic dissection surgery is a risk factor for morbidity and mortality. Because postoperative thrombocytopenia can indicate a poor prognosis, monitoring early postoperative platelets he…
View article: Contemporary use and outcome of Cabrol shunt in type A aortic dissection surgery: insight from China 5A study
Contemporary use and outcome of Cabrol shunt in type A aortic dissection surgery: insight from China 5A study Open
Objective Cabrol shunt has been introduced for surgical repair of type A aortic dissection (TAAD) without robust evidence supporting its routine preventive use. Methods Adult patients with TAAD from China 5A study were included if surgical…
View article: In Situ Needle Fenestration for Aortic Arch Pathologies During Thoracic Endovascular Aortic Repair
In Situ Needle Fenestration for Aortic Arch Pathologies During Thoracic Endovascular Aortic Repair Open
Background To evaluate the clinical outcomes and the validity of the in situ needle fenestration (ISNF) technique during thoracic endovascular aortic repair (TEVAR) for patients with aortic arch pathologies. Methods In total, 115 patients …
View article: 2023 APHRS expert consensus statements on surgery for <scp>AF</scp>
2023 APHRS expert consensus statements on surgery for <span>AF</span> Open
A variety of surgical procedures for atrial fibrillation (AF) with different approaches have become available during the last quarter century, starting with the Maze procedure to the minimally invasive procedures. Asia-Pacific region is an…
View article: Traumatic Gerbode defect and aortic dissection
Traumatic Gerbode defect and aortic dissection Open
View article: False lumen–dependent segmental arteries are associated with spinal cord injury in frozen elephant trunk procedure for acute type I aortic dissection
False lumen–dependent segmental arteries are associated with spinal cord injury in frozen elephant trunk procedure for acute type I aortic dissection Open
FL dependency of SAs at the T9-L3 levels was significantly associated with the development of SCI following FET implantation in AAD, warning against its uses on patients presenting with FL dependency of SAs at critical segments.
View article: Frequency of prothrombin time-international normalized ratio monitoring and the long-term prognosis in patients with mechanical valve replacement
Frequency of prothrombin time-international normalized ratio monitoring and the long-term prognosis in patients with mechanical valve replacement Open
View article: Inflammatory risk stratification individualizes anti-inflammatory pharmacotherapy for acute type A aortic dissection
Inflammatory risk stratification individualizes anti-inflammatory pharmacotherapy for acute type A aortic dissection Open
The systemic benefits of anti-inflammatory pharmacotherapy vary across cardiovascular diseases in clinical practice. We aimed to evaluate the application of artificial intelligence to acute type A aortic dissection (ATAAD) patients to dete…
View article: Valve-in-valve/valve-in-ring transcatheter mitral valve implantation vs. redo surgical mitral valve replacement for patients with failed bioprosthetic valves or annuloplasty rings: A systematic review and meta-analysis
Valve-in-valve/valve-in-ring transcatheter mitral valve implantation vs. redo surgical mitral valve replacement for patients with failed bioprosthetic valves or annuloplasty rings: A systematic review and meta-analysis Open
ViV/ViR TMVI is a reliable alternative to redo SMVR for failed bioprosthetic valves or annuloplasty rings as a result of lower in-hospital mortality, higher 30-day survival, and lower early postoperative complication rates, although there …
View article: Preoperative Predictors of Late Aortic Expansion in Acute Type B Aortic Dissection Treated with TEVAR
Preoperative Predictors of Late Aortic Expansion in Acute Type B Aortic Dissection Treated with TEVAR Open
Background: A patent false lumen (FL) in patients with thoracic endovascular aortic repair (TEVAR)-treated type B aortic dissection (TBAD) can cause a significant risk for late aortic expansion (LAE). We hypothesize that preoperative featu…