Yonghui Wang
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View article: Polyethylene terephthalate (PET) microplastics induced male reproductive toxicity in mice by activating the p38-MAPK pathway
Polyethylene terephthalate (PET) microplastics induced male reproductive toxicity in mice by activating the p38-MAPK pathway Open
View article: Biogeographic Patterns and Ecological Roles of Microorganisms in Sediments Along an Estuarine Salinity Gradient
Biogeographic Patterns and Ecological Roles of Microorganisms in Sediments Along an Estuarine Salinity Gradient Open
The distribution patterns and driving mechanisms of microbial biogeographic patterns are fundamental questions in microbiology. This study analysed and compared the bacterial biogeographic patterns in the coastal environment, focusing on t…
View article: HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction Open
This study indicated that the gut microecological mechanism of FSN might be associated with its herbal components, which regulate gut microbiota diversity, restore the intestinal barrier, and boost microbial metabolite production. Furtherm…
View article: Management of a female patient with thyroid storm accompanied by acute airway obstruction: A case report
Management of a female patient with thyroid storm accompanied by acute airway obstruction: A case report Open
Thyroid storm (TS) is a life-threatening exacerbation of the hyperthyroid state. Acute airway obstruction is a life-threatening disease that requires emergency intervention. The present report describes a case of concomitant TS (Burch-Wart…
View article: Metabolic pathway and genetically causal links of 1,400 circulating metabolites on the risk of intracranial aneurysms and aneurysmal subarachnoid hemorrhage
Metabolic pathway and genetically causal links of 1,400 circulating metabolites on the risk of intracranial aneurysms and aneurysmal subarachnoid hemorrhage Open
This study found that nine circulating metabolites and their ratios with significant causal associations to aSAH, while no metabolites and their ratios were causally linked to IAs. These results suggest possible mechanisms and predictive m…
View article: Effects of Allyloxy Substitution on Photochemical Properties of Thioxanthones and Their Application in Visible-Led Photopolymerization
Effects of Allyloxy Substitution on Photochemical Properties of Thioxanthones and Their Application in Visible-Led Photopolymerization Open
View article: Propolis does not significantly modulate immune function in an older population: A preliminary study
Propolis does not significantly modulate immune function in an older population: A preliminary study Open
Chinese propolis could stimulate IgG secretion within a certain period, but it was restored to baseline levels over time. Propolis does not significantly affect other immune markers in the elderly.
View article: Ultrasonic‐assisted extraction of nanocellulose from sweet potato residue and its application in noodles
Ultrasonic‐assisted extraction of nanocellulose from sweet potato residue and its application in noodles Open
Enhancing the amount of dietary fiber without compromising the quality of noodles remains a challenge in the food industry. This study aimed to optimize the ultrasound‐assisted extraction parameters to enhance the yield of nanocellulose fr…
View article: Enhanced One/Two‐Photon Initiating Performance of Nitro‐Carbazole‐Styrene Based Oxime/Ketoxime Esters
Enhanced One/Two‐Photon Initiating Performance of Nitro‐Carbazole‐Styrene Based Oxime/Ketoxime Esters Open
Comprehensive Summary Photoinitiators of the oxime ester (OXE) or ketoxime ester (OXE‐CO) type can rapidly undergo N—O bond cleavage and generate free radicals to initiate photopolymerization under LED excitation, occupying an important po…
View article: Modifiers of the Effects of Vitamin D Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis
Modifiers of the Effects of Vitamin D Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis Open
The inconsistent findings concerning the effects of vitamin D supplementation on cardiometabolic risk factors and the large heterogeneity in the published literature call for further research to identify sources of heterogeneity and potent…
View article: Monodisperse Manganese‐Vanadium‐Oxo Clusters with Extraordinary Lithium Storage
Monodisperse Manganese‐Vanadium‐Oxo Clusters with Extraordinary Lithium Storage Open
Although possessing well‐defined nanostructures and excellent multi‐electron redox properties, polyoxometalate clusters have poor intrinsic electrical conductivity and are prone to aggregation due to large surface energy, which makes them …
View article: GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus
GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus Open
Recombinant adenovirus (rAdV) is a commonly used vector system for gene transfer. Efficient initial packaging and subsequent production of rAdV remains time-consuming and labor-intensive, possibly attributable to rAdV infection-associated …
View article: Correction to “Mannosylated STING Agonist Drugamers for Dendritic Cell-Mediated Cancer Immunotherapy”
Correction to “Mannosylated STING Agonist Drugamers for Dendritic Cell-Mediated Cancer Immunotherapy” Open
[This corrects the article DOI: 10.1021/acscentsci.3c01310.].
View article: Mannosylated STING Agonist Drugamers for Dendritic Cell-Mediated Cancer Immunotherapy
Mannosylated STING Agonist Drugamers for Dendritic Cell-Mediated Cancer Immunotherapy Open
The Stimulator of Interferon Genes (STING) pathway is a promising target for cancer immunotherapy. Despite recent advances, therapies targeting the STING pathway are often limited by routes of administration, suboptimal STING activation, o…
View article: A unilateral external fixator combined with bone transport and tibio-talar fusion for the treatment of severe postoperative infection of peri-ankle fractures: retrospective analysis of 32 cases
A unilateral external fixator combined with bone transport and tibio-talar fusion for the treatment of severe postoperative infection of peri-ankle fractures: retrospective analysis of 32 cases Open
View article: Preparation and demulsification performance of magnetic demulsifier Fe<sub>3</sub>N@F
Preparation and demulsification performance of magnetic demulsifier Fe<sub>3</sub>N@F Open
By observing the microdroplet microstructure before and after demulsification, it is found that the Fe 3 N@F magnetic demulsifier exhibits favorable coalescence, flocculation, and bridging capabilities.
View article: Mof@Cof Nanocomposite with Multiple Active Sites: Efficient Adsorbents for Carbamate Pesticides Removal
Mof@Cof Nanocomposite with Multiple Active Sites: Efficient Adsorbents for Carbamate Pesticides Removal Open
View article: Closed-Loop Recyclable Polyimine Vitrimer with Multi-Stimulus Response and Flame Retardancy
Closed-Loop Recyclable Polyimine Vitrimer with Multi-Stimulus Response and Flame Retardancy Open
View article: Mild Preparation and Photocuring Performance of Itaconic Acid-Derived Hyperbranched Macromers with Internal and Terminal C=C Bonds Catalyzed by Tetramethylguanidine
Mild Preparation and Photocuring Performance of Itaconic Acid-Derived Hyperbranched Macromers with Internal and Terminal C=C Bonds Catalyzed by Tetramethylguanidine Open
View article: Mechanism insight into the high-efficiency catalytic killing of <i>E. coli</i> by metal–phenolic network as a nanozyme
Mechanism insight into the high-efficiency catalytic killing of <i>E. coli</i> by metal–phenolic network as a nanozyme Open
CuTA nanozymes with dual functional properties similar to peroxidase-like activity and GSH depletion. CuTA can catalyze the decomposition of H 2 O 2 to hydroxyl radicals (˙OH). CuTA has an excellent antibacterial effect against E. coli .
View article: Adipose-derived mesenchymal stem cells (MSCs) are a superior cell source for bone tissue engineering
Adipose-derived mesenchymal stem cells (MSCs) are a superior cell source for bone tissue engineering Open
View article: Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy
Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy Open
The master transcription factor receptor retinoic acid receptor-related orphan receptor γt (RORγt) regulates the differentiation of T-helper 17 (Th17) cells and the production of interleukin-17 (IL-17). Activation of RORγt+ T ce…
View article: Educational value of mixed reality combined with a three-dimensional printed model of aortic disease for vascular surgery in the standardized residency training of surgical residents in China: a case control study
Educational value of mixed reality combined with a three-dimensional printed model of aortic disease for vascular surgery in the standardized residency training of surgical residents in China: a case control study Open
Background The simulated three-dimensional (3D) printed anatomical model of the aorta, which has become the norm in medical education, has poor authenticity, tactility, feasibility, and interactivity. Therefore, this study explored the edu…
View article: Fast Fluorescence Sensing of Aflatoxin B1 Employing a Europium Metal--Organic Framework Avoiding Self-Fluorescence Interference of Target
Fast Fluorescence Sensing of Aflatoxin B1 Employing a Europium Metal--Organic Framework Avoiding Self-Fluorescence Interference of Target Open
The rapid monitoring of food safety plays a key role in the food industry. Here, we have prepared a lanthanide metallo-organic framework Eu-TCPP, which can selectively detect aflatoxin B1, showing an ultrafast response of 5 min, a detectio…
View article: Clinical characteristics and treatment efficacy of immune checkpoint inhibitors (ICIs) in patients with ICIs-induced Adrenal insufficiency
Clinical characteristics and treatment efficacy of immune checkpoint inhibitors (ICIs) in patients with ICIs-induced Adrenal insufficiency Open
ICI-induced AI is a rare irAE, and close monitoring of cortisol levels is important. Patients diagnosed with AI after receiving immunotherapy seem to have a favorable outcome.
View article: Mixed medullary‑follicular thyroid carcinoma: A case report and literature review
Mixed medullary‑follicular thyroid carcinoma: A case report and literature review Open
Papillary thyroid cancer (PTC) and medullary thyroid cancer (MTC) originate from follicular and neuroendocrine parafollicular C cells, respectively. PTC and MTC simultaneously exist in tumors containing both MTC and PTC features in a rare …
View article: Author Correction: Study on the preparation and mechanical properties of purple ceramics
Author Correction: Study on the preparation and mechanical properties of purple ceramics Open
View article: The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities
The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities Open
View article: Structural insights into dual-antagonize mechanism of AB928 on adenosine A<sub>2</sub>receptors
Structural insights into dual-antagonize mechanism of AB928 on adenosine A<sub>2</sub>receptors Open
The adenosine subfamily G protein-coupled receptors A 2A R and A 2B R were identified as promising candidates for cancer immunotherapy within recent years. One of the A 2A R/A 2B R dual antagonist, AB928, has progressed to phase II clinic …
View article: Identification of tau-tubulin kinase 1 inhibitors by microfluidics-based mobility shift assay from a kinase inhibitor library
Identification of tau-tubulin kinase 1 inhibitors by microfluidics-based mobility shift assay from a kinase inhibitor library Open
Tau tubulin kinase 1 (TTBK1) is a serine/threonine/tyrosine kinase that phosphorylates multiple residues in tau protein. Hyperphosphorylated tau is the main cause of tauopathy, such as Alzheimer's disease (AD). Therefore, preventing tau ph…