Explanipedia

Noninvasive monitoring of fetal tissue oxygenation level using time-domain NIRS Open

Zhen Guo, Yongyi Zhao, Yongfeng Yang, Ankit Raghuram, Martin P. Debreczeny , et al. · 2025

The results suggest a significant potential for the use of TD-NIRS to noninvasively and safely monitor the fetal oxygenation level.

Reconstruction of total-body multi parametric images with shortened-duration dynamic [<sup>68</sup>Ga]Ga-PSMA-11 and [<sup>68</sup>Ga]Ga-FAPI-04 PET scans Open

Yunlong Gao, Zixiang Chen, Wenjie Zhao, Yongfeng Yang, Hairong Zheng , et al. · 2025

Objective. The lengthy 1 h dynamic positron emission tomography (PET) scans discomfort patients, add motion artifacts, and inflate costs, highlighting the need for tech advancements to reduce scan times. Therefore, we attempted to reconstr…

The Mirage of Multimodality: Where Truth is Tested and Honesty Unravels Open

Jiaming Ji, Sitong Fang, Wenjing Cao, Jiahao Li, X. Wang , et al. · 2025

Reasoning models have recently attracted significant attention, especially for tasks that involve complex inference. Their strengths exemplify the System II paradigm (slow, structured thinking), contrasting with the System I (rapid, heuris…

Machine learning positioning algorithms for long semi-monolithic scintillator PET detectors Open

Samuel Mungai Kinyanjui, Zhonghua Kuang, Zheng Liu, Ning Ren, Yongfeng Yang · 2025

Objective. In this work, machine learning positioning algorithms are developed to improve the spatial resolutions of the semi-monolithic scintillator detectors in both monolithic ( y ) and depth of interaction ( z ) directions. Approach. T…

Phosphoenolpyruvate carboxykinase 2 Could Be Used For distiguishment Of Hepatoblastoma And Affecting Ferroptosis Open

Wei Li, Xinlong ZHANG, Yongfeng Yang, Zhengcun ZHOU, Zhenzhen Huang , et al. · 2025

Hepatoblastoma (HB) is the most common malignant liver tumor in children, with low cure rates due to the lack of accurate predictive tar-gets. Phosphoenolpyruvate carboxykinase 2 (PCK2) has been implicated in various tumors and may regulat…

Bidirectional dynamic frame prediction network for total-body [68Ga]Ga-PSMA-11 and [68Ga]Ga-FAPI-04 PET images Open

Qianyi Yang, Wenbo Li, Zhenxing Huang, Zixiang Chen, Wenjie Zhao , et al. · 2024

In this work, we propose a bidirectional dynamic frame prediction network for total-body ⁶⁸Ga-PSMA and ⁶⁸Ga-FAPI PET imaging with a reduced scan duration. Visual and quantitative analyses demonstrated that our approac…

From Incomplete Coarse-Grained to Complete Fine-Grained: A Two-Stage Framework for Spatiotemporal Data Reconstruction Open

Zhixin Sun, Haoyang Su, En Wang, Funing Yang, Yongfeng Yang , et al. · 2024

With the rapid development of various sensing devices, spatiotemporal data is becoming increasingly important nowadays. However, due to sensing costs and privacy concerns, the collected data is often incomplete and coarse-grained, limiting…

Pharmacovigilance study of GLP-1 receptor agonists for metabolic and nutritional adverse events Open

Long He, Qiuyu Li, Yongfeng Yang, Jiahao Li, Wei Luo , et al. · 2024

Aims: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are employed extensively in the management of type 2 diabetes and obesity. However, there is a paucity of real-world data on their safety and tolerability for metabolic and nutrit…

Correction: Comparing Sonazoid contrast-enhanced ultrasound to contrast-enhanced CT and MRI for differentially diagnosing renal lesions: a prospective multicenter study Open

Qinxian Zhao, Chong Wu, Shuilian Tan, Yongfeng Yang, Xin‐Wu Cui , et al. · 2024

The role of dynamic, static, and delayed total-body PET imaging in the detection and differential diagnosis of oncological lesions Open

Yaping Wu, Fangfang Fu, Nan Meng, Zhenguo Wang, Xiaochen Li , et al. · 2024

Objectives Commercialized total-body PET scanners can provide high-quality images due to its ultra-high sensitivity. We compared the dynamic, regular static, and delayed 18F-fluorodeoxyglucose (FDG) scans to detect lesions in oncologic pat…

Reducing pediatric total-body PET/CT imaging scan time with multimodal artificial intelligence technology Open

Qiyang Zhang, Yingying Hu, Chao Zhou, Yumo Zhao, Na Zhang , et al. · 2024

Objectives This study aims to decrease the scan time and enhance image quality in pediatric total-body PET imaging by utilizing multimodal artificial intelligence techniques. Methods A total of 270 pediatric patients who underwent total-bo…

Effect of depth of interaction resolution on the spatial resolution of SIAT aPET Open

Zhonghua Kuang, Ling Zhang, Ning Ren, Samuel M. Kinyanjui, Zheng Liu , et al. · 2023

Objective. Spatial resolution is a crucial parameter for a positron emission tomography (PET) scanner. The spatial resolution of a high-resolution small animal PET scanner is significantly influenced by the effect of depth of interaction (…

Low-count PET image reconstruction based on truncated inverse radon layer and U-shaped network Open

Jianbo Ye, Zhonghua Kuang, Yongfeng Yang, Ke Cui, Xiangyu Li · 2023

Objective. Positron emission tomography (PET) is a functional imaging widely used in various applications such as tumour detection. PET image reconstruction is an ill-posed inverse problem, and the model-based iterative reconstruction meth…

Front Cover Open

Min-Jun Fu, Mingfu Wang, Yonghui Wu, Nong Zhang, Yongfeng Yang , et al. · 2023

Edge effect reduction of high-resolution PET detectors using LYSO and GAGG phoswich crystals Open

Zheng Liu, Samuel Mungai, Ming Niu, Zhonghua Kuang, Ning Ren , et al. · 2023

Objective . Small-animal positron emission tomography (PET) is a powerful preclinical imaging tool in animal model studies. The spatial resolution and sensitivity of current PET scanners developed for small-animal imaging need to be improv…

Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity Open

Liang Yang, Junfeng Shen, Chunhua Liu, Zhonghua Kuang, Yong Tang , et al. · 2023

Imbalances in NAD + homeostasis have been linked to aging and various diseases. Nicotine, a metabolite of the NAD + metabolic pathway, has been found to possess anti-inflammatory and neuroprotective properties, yet the underlying molecular…

Review of: "centrifugeR: Non-trivial balance of centrifuge rotors" Open

Yongfeng Yang · 2023

Potential competing interests: No potential competing interests to declare.I think this paper focus on the balancing of an centrifuges instruments.If the test sample is even number.It's quite easy.The key question is the odd number test sa…

Toward a Dual Dose Reduction Strategy of a Total-Body PET/CT System for Attenuation-Corrected PET Imaging via Deep Learning Open

Zhenxing Huang, Wenbo Li, Yanhua Duan, Haiyan Wang, Yongfeng Yang , et al. · 2023

Motion correction and its impact on quantification in dynamic total-body 18F-fluorodeoxyglucose PET Open

Tao Sun, Yaping Wu, Wei Wei, Fangfang Fu, Nan Meng , et al. · 2022

Comparison between a dual-time-window protocol and other simplified protocols for dynamic total-body 18F-FDG PET imaging Open

Zhenguo Wang, Yaping Wu, Xiaochen Li, Yan Bai, Hongzhao Chen , et al. · 2022

Identifying the individual metabolic abnormities from a systemic perspective using whole-body PET imaging Open

Tao Sun, Zhenguo Wang, Yaping Wu, Fengyun Gu, Xiaochen Li , et al. · 2022

High resolution detectors for whole-body PET scanners by using dual-ended readout Open

Zheng Liu, Ming Niu, Zhonghua Kuang, Ning Ren, S. Wu , et al. · 2022

Identifying Mild Alzheimer's Disease With First 30-Min 11C-PiB PET Scan Open

Chushu Shen, Zhenguo Wang, Hongzhao Chen, Yan Bai, Xiaochen Li , et al. · 2022

Introduction 11 C-labeled Pittsburgh compound B ( 11 C-PiB) PET imaging can provide information for the diagnosis of Alzheimer's disease (AD) by quantifying the binding of PiB to β-amyloid deposition in the brain. Quantification index, suc…

In vivo development and single‐cell transcriptome profiling of human brain organoids Open

Shichao Huang, Fei Huang, Huiying Zhang, Yongfeng Yang, Juan Lu , et al. · 2022

Objectives Human brain organoids can provide not only promising models for physiological and pathological neurogenesis but also potential therapies in neurological diseases. However, technical issues such as surgical lesions due to transpl…

Low-Dose 68 Ga-PSMA Prostate PET/MRI Imaging Using Deep Learning Based on MRI Priors Open

Fuquan Deng, Xiaoyuan Li, Fengjiao Yang, Hongwei Sun, Jianmin Yuan , et al. · 2022

Background 68 Ga-prostate-specific membrane antigen (PSMA) PET/MRI has become an effective imaging method for prostate cancer. The purpose of this study was to use deep learning methods to perform low-dose image restoration on PSMA PET/MRI…

Ultralow-Dose Pediatric Total-Body PET/CT Imaging Using an Artificial Intelligence Technique Open

Qiyang Zhang, Zizheng Xiao, Xu Zhang, Yingying Hu, Yumo Zhao , et al. · 2022

Accurate Total-Body Ki Parametric Imaging with Shortened Dynamic 18F-FDG PET Scan Durations via Effective Data Processing Open

Zixiang Chen, Zhaoping Cheng, Yanhua Duan, Fengyun Gu, Ying Wang , et al. · 2021

Background : Total-body dynamic PET (dPET) imaging using 18 F-fluorodeoxyglucose ( 18 F-FDG) has received widespread attention in clinical oncology. However, the conventionally required scan duration of approximately one hour seriously lim…

Low-Dose 68 Ga-PSMA Prostate PET/MRI Imaging Using Deep Learning Based On MR Priors Open

Fuquan Deng, Xiaoyuan Li, Fengjiao Yang, Hongwei Sun, Jianmin Yuan , et al. · 2021

Purpose: 68 Ga-prostate-specific membrane antigen (PSMA) PET/MRI has become an effective imaging method for prostate cancer. The purpose of this study was to use deep learning methods to perform low-dose image restoration on PSMA PET/MRI a…

High temporal resolution total-body dynamic PET/CT imaging based on third-order Hermite interpolation Open

Zixiang Chen, Yaping Wu, Na Zhang, Yu Shen, Chenwei Li , et al. · 2021

Dynamic positron emission tomography (dPET) is currently a widely used medical imaging technique for the clinical diagnosis, staging and therapy guidance of all kinds of human cancers. Higher temporal imaging resolution for the early stage…

Valuable Characteristic of Patlak Parametric Imaging Based on Total-Body Dynamic PET Imaging: Higher Contrast For Tumor Lesions With Respect To Hypermetabolic Tissues Open

Zixiang Chen, Yanhua Duan, Chenwei Li, Ying Wang, Yongfeng Yang , et al. · 2021

Purpose To demonstrate the characteristics of high-contrast tumor lesions on total-body dynamic positron emission tomography (dPET) parametric images qualitatively and quantitatively. Method We reported the results of Patlak parametric ima…

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