Yongjiang Chen
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View article: Effect of the tubeless approach on the non-operative lung in thoracic surgery: a retrospective cohort study
Effect of the tubeless approach on the non-operative lung in thoracic surgery: a retrospective cohort study Open
Tubeless approach is associated with lower mechanical ventilation pressures and less overall image abnormalities, potentially protecting the non-operative lung. These findings suggest that tubeless approach has protective effect on the non…
View article: Expert Consensus on Subxiphoid and Subcostal Arch Thoracoscopic Resection for the Treatment of Thymoma
Expert Consensus on Subxiphoid and Subcostal Arch Thoracoscopic Resection for the Treatment of Thymoma Open
Surgery is the primary treatment for thymoma. Although subxiphoid and subcostal arch thoracoscopic thymoma surgery is widely used, there is currently a lack of consensus regarding its use, nor have standards been established. Based on the …
View article: Ex-vivo lung resection and autotransplantation for primary pulmonary artery sarcoma
Ex-vivo lung resection and autotransplantation for primary pulmonary artery sarcoma Open
View article: A better option for localization of multiple pulmonary nodules in the ipsilateral lung: electromagnetic navigation bronchoscopy-guided preoperative localization
A better option for localization of multiple pulmonary nodules in the ipsilateral lung: electromagnetic navigation bronchoscopy-guided preoperative localization Open
For patients with multiple ipsilateral pulmonary nodules, ENBDM can achieve the similar localization accuracy as CT-guided lung puncture, with shorter localization time and no complications. ENBDM is a safe and effective preoperative local…
View article: Lung autotransplantation for advanced central lung cancer after neoadjuvant immuno-chemotherapy: a case series study
Lung autotransplantation for advanced central lung cancer after neoadjuvant immuno-chemotherapy: a case series study Open
Lung autotransplantation for advanced central NSCLC after neoadjuvant immuno-chemotherapy is feasible and safe, with maximal preservation of lung function and a high rate of R0 resection. This also demonstrates the advantages of organ pres…
View article: A high-fat plus high-sucrose diet induces age-related macular degeneration in an experimental rabbit model
A high-fat plus high-sucrose diet induces age-related macular degeneration in an experimental rabbit model Open
Age-related macular degeneration (AMD) is a leading cause of blindness. Metabolic disorders and diets are risk factors. We compared lipid profiles and retinal phenotypes with long-term feeding of four diets in male Chinchilla rabbits. Anim…
View article: Sub-lobar resection versus lobectomy for challenging intraoperative frozen sections in lung adenocarcinoma within 3 cm
Sub-lobar resection versus lobectomy for challenging intraoperative frozen sections in lung adenocarcinoma within 3 cm Open
Indeterminate intraoperative FSs, posing diagnostic challenges in distinguishing between MIA and IAC. Sub-lobar resection presented the same long term survival benefit compared with the lobectomy for indeterminate lung adenocarcinoma withi…
View article: Performance verification of a biochemical detection system for hydrothorax and ascites and clinical diagnostic accuracy evaluation of exudate and tuberculous effusion
Performance verification of a biochemical detection system for hydrothorax and ascites and clinical diagnostic accuracy evaluation of exudate and tuberculous effusion Open
The LDH, TP, Glu, and ADA assays were validated for use with the Mindray BS-2800 analyzer for hydrothorax and ascites evaluation. LDH, TP, and Glu in hydrothorax and ascites are applicable to the differential diagnosis of exudates and tran…
View article: The role of the microbiota in glaucoma
The role of the microbiota in glaucoma Open
Glaucoma is a common irreversible vision loss disorder because of the gradual loss of retinal ganglion cells (RGCs) and the optic nerve axons. Major risk factors include elder age and high intraocular pressure (IOP). However, high IOP is n…
View article: Hyperlipidemia and lipid-lowering therapy in diabetic retinopathy (DR): A bibliometric study and visualization analysis in 1993–2023
Hyperlipidemia and lipid-lowering therapy in diabetic retinopathy (DR): A bibliometric study and visualization analysis in 1993–2023 Open
View article: Utilization of intraoperative indocyanine green fluorescence imaging to identify vascular anatomy in severe pleural adhesions in uniportal video-assisted thoracoscopic surgery: a case report
Utilization of intraoperative indocyanine green fluorescence imaging to identify vascular anatomy in severe pleural adhesions in uniportal video-assisted thoracoscopic surgery: a case report Open
The ICG fluorescence imaging is used to illustrate the vessels and help to dissect them safely, which is a feasible, visualizable, and user-friendly method in severe pleural adhesions in uniportal VATS.
View article: Feasibility of resection after neoadjuvant chemotherapy for mediastinal yolk sac tumor
Feasibility of resection after neoadjuvant chemotherapy for mediastinal yolk sac tumor Open
View article: The heterogeneity of astrocytes in glaucoma
The heterogeneity of astrocytes in glaucoma Open
Glaucoma is a leading cause of blindness with progressive degeneration of retinal ganglion cells. Aging and increased intraocular pressure (IOP) are major risk factors. Lowering IOP does not always stop the disease progression. Alternative…
View article: The Role of the Microbiota in Graves’ Disease and Graves’ Orbitopathy
The Role of the Microbiota in Graves’ Disease and Graves’ Orbitopathy Open
Graves‘ disease (GD) is a clinical syndrome with an enlarged and overactive thyroid gland, an accelerated heart rate, Graves’ orbitopathy (GO), and pretibial myxedema (PTM). GO is the most common extrathyroidal complication of GD. GD/GO ha…
View article: Clinical Pathological Features and Current Animal Models of Type 3 Macular Neovascularization
Clinical Pathological Features and Current Animal Models of Type 3 Macular Neovascularization Open
Type 3 macular neovascularization (MNV3), or retinal angiomatous proliferation (RAP), is a distinct type of neovascular age-related macular degeneration (AMD), which is a leading cause of vision loss in older persons. During the past decad…
View article: Body Composition Parameters May Be Prognostic Factors in Upper Urinary Tract Urothelial Carcinoma Treated by Radical Nephroureterectomy
Body Composition Parameters May Be Prognostic Factors in Upper Urinary Tract Urothelial Carcinoma Treated by Radical Nephroureterectomy Open
Objective This study assessed the association between body composition and prognosis of patients with upper urinary tract urothelial carcinoma (UTUC) patients treated by radical nephroureterectomy. Methods We retrospectively collected base…
View article: Interaction Between Mesenchymal Stem Cells and Retinal Degenerative Microenvironment
Interaction Between Mesenchymal Stem Cells and Retinal Degenerative Microenvironment Open
Retinal degenerative diseases (RDDs) are a group of diseases contributing to irreversible vision loss with yet limited therapies. Stem cell-based therapy is a promising novel therapeutic approach in RDD treatment. Mesenchymal stromal/stem …
View article: The Role of Gut Microbiome in Autoimmune Uveitis
The Role of Gut Microbiome in Autoimmune Uveitis Open
The gut microbiome has important physiological functions and plays an indispensable role in the human body. Currently, there are an increasing number of studies revealing the close correlation between dysbiosis of the gut microbiome and a …
View article: Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma
Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma Open
Von Hippel-Lindau (Vhl) protein inhibits hypoxia-inducible factor (Hif), yet its deletion in murine retina does not cause the extensive angiogenesis expected with Hif induction. The mechanism is unclear. Here we show that retinoblastoma tu…
View article: Rb is required for retinal angiogenesis and lamination
Rb is required for retinal angiogenesis and lamination Open
Retinoblastoma tumor suppressor (Rb) promotes cell cycle exit, survival, differentiation, and tumor suppression in the retina. Here, we show it is also essential for vascularization and lamination. Despite minimal effects on Hif1a target e…