Yaohua Chen
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View article: The Global Impact of COVID‐19 Control Measures on People With Dementia Living at Home and Their Carers: A Systematic Review of Quantitative and Qualitative Research Across 27 Countries
The Global Impact of COVID‐19 Control Measures on People With Dementia Living at Home and Their Carers: A Systematic Review of Quantitative and Qualitative Research Across 27 Countries Open
Background COVID‐19 control measures have had a unique impact on people with dementia (PWD) and their carers living at home. Yet, uncertainty exists regarding the global impact of such measures and whether differences exist between countri…
View article: Light-triggered carbon monoxide-induced activation of enhanced ferritinophagy-mediated ferroptosis for bone metastases therapy
Light-triggered carbon monoxide-induced activation of enhanced ferritinophagy-mediated ferroptosis for bone metastases therapy Open
Bone metastases, as a common disabling and life-threatening complication in the advanced stages of various solid tumors, continue to pose substantial therapeutic challenges due to high drug toxicity and tumor resistance. To overcome the li…
View article: The global impact of COVID-19 control measures on people with dementia living at home and their carers during the two first waves: A systematic review of quantitative and qualitative research across 27 countries
The global impact of COVID-19 control measures on people with dementia living at home and their carers during the two first waves: A systematic review of quantitative and qualitative research across 27 countries Open
Background COVID-19 control measures have had a unique impact on people with dementia (PWD) and their carers living at home. Yet, uncertainty exists regarding the global impact of such measures, and whether differences exist between countr…
View article: Prediction of the Efficacy and Prognosis of Anlotinib in Lung Cancer Patients Using CT Radiomics
Prediction of the Efficacy and Prognosis of Anlotinib in Lung Cancer Patients Using CT Radiomics Open
Purpose: Our study aimed to develop and validate a predictive model based on chest CT radiomics features combined with clinical variables to evaluate the efficacy of anlotinib and its prognostic value in patients with advanced lung cancer.…
View article: Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus
Case Report: Sympathetic nerve block treat chronic kidney disease-associated pruritus Open
Uremia is the advanced stage of chronic kidney disease (CKD), characterized by the accumulation of metabolic waste products in the blood as a result of the kidneys' inability to meet the body's metabolic demands. Patients with uremia frequ…
View article: Fall Risk Factors and Other Geriatric Syndromes in Older Adults With Diabetes: Experience of a Multidisciplinary Fall Consultation
Fall Risk Factors and Other Geriatric Syndromes in Older Adults With Diabetes: Experience of a Multidisciplinary Fall Consultation Open
Aims: The aim of this study is to assess the prevalence of diabetes in patients attending a multidisciplinary consultation for fall risk assessment and to compare fall risk factors and the prevalence of other geriatric syndromes in patient…
View article: Factors associated with loneliness in Latin-American family care partners during the COVID-19 pandemic
Factors associated with loneliness in Latin-American family care partners during the COVID-19 pandemic Open
Background COVID-19-related restrictions led to an increase in overall loneliness and social isolation. Before the pandemic, care partners reported higher levels of loneliness and higher loneliness prevalence compared to non-care partners.…
View article: New horizons in hospital-associated deconditioning: a global condition of body and mind
New horizons in hospital-associated deconditioning: a global condition of body and mind Open
Hospital-associated deconditioning is a broad term, which refers non-specifically to declines in any function of the body secondary to hospitalisation. Older people, particularly those living with frailty, are known to be at greatest risk.…
View article: Identifying Gaps and Barriers in Alzheimer’s Disease and Related Dementia Research and Management in Low- and Middle-Income Countries: A Survey of Health Professionals and Researchers
Identifying Gaps and Barriers in Alzheimer’s Disease and Related Dementia Research and Management in Low- and Middle-Income Countries: A Survey of Health Professionals and Researchers Open
Background: The significant increase in Alzheimer’s disease and related dementia prevalence is a global health crisis, acutely impacting low- and lower-middle and upper-middle-income countries (LLMICs/UMICs). Objective: The objective of th…
View article: Construction and analysis of a lysosome-dependent cell death score-based prediction model for non-small cell lung cancer
Construction and analysis of a lysosome-dependent cell death score-based prediction model for non-small cell lung cancer Open
The study showed a significant increase in the proportion of monocytes in NSCLC tissues, suggesting their important role in cancer progression. Cell communication analysis indicated that macrophages, smooth muscle cells, and myeloid cells …
View article: Assessment of Mendelian and risk-factor genes in Alzheimer disease: A prospective nationwide clinical utility study and recommendations for genetic screening
Assessment of Mendelian and risk-factor genes in Alzheimer disease: A prospective nationwide clinical utility study and recommendations for genetic screening Open
View article: Exploration of nursing cooperation strategies for intravenous indwelling needle in CT enhanced examination
Exploration of nursing cooperation strategies for intravenous indwelling needle in CT enhanced examination Open
To investigate nursing collaboration strategies concerning intravenous indwelling needles in CT-enhanced examinations, an experiment was conducted among patients undergoing diagnosis and treatment at a Chinese hospital between August 2020 …
View article: Clinical value of enhanced CT in the diagnosis of pulmonary sequestration
Clinical value of enhanced CT in the diagnosis of pulmonary sequestration Open
To explore the clinical value of enhanced CT in the diagnosis of pulmonary sequestration, our hospital randomly selected 100 patients with suspected pulmonary sequestration as the experimental study subjects between 2014 and 2021. All pati…
View article: The early diagnostic value of dimer combined with abdominal CT in patients with ischemic colitis
The early diagnostic value of dimer combined with abdominal CT in patients with ischemic colitis Open
To analyze the value of intraperitoneal injection of Maikangping in the early diagnosis of ischemic colitis (IC) patients, the results of abdominal digital subtraction angiography (DSA) were used as a control. By organizing time and combin…
View article: The Impact of the COVID-19 Pandemic on the Psychological Well-Being of Caregivers of People with Dementia or Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
The Impact of the COVID-19 Pandemic on the Psychological Well-Being of Caregivers of People with Dementia or Mild Cognitive Impairment: A Systematic Review and Meta-Analysis Open
The aim of this systematic review was to investigate the effects of the COVID-19 lockdown on the psychological well-being of caregivers of people with dementia or mild cognitive impairment (PwD/MCI). Electronic databases were searched from…
View article: Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline
Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline Open
View article: Emerging disease modifying therapies for older adults with Alzheimer disease: perspectives from the EuGMS special interest group in dementia
Emerging disease modifying therapies for older adults with Alzheimer disease: perspectives from the EuGMS special interest group in dementia Open
View article: A call for clinical trial globalization in Alzheimer's disease and related dementia
A call for clinical trial globalization in Alzheimer's disease and related dementia Open
Background The burden of Alzheimer's disease and related dementia (ADRD) is projected to disproportionally impact low‐middle‐income countries (LMICs). However, there is a systematic under‐representation of LMICs in ADRD clinical trial plat…
View article: Impact of COVID-19 Pandemic on Caregivers of People with an Intellectual Disability, in Comparison to Carers of Those with Other Disabilities and with Mental Health Issues: A Multicountry Study
Impact of COVID-19 Pandemic on Caregivers of People with an Intellectual Disability, in Comparison to Carers of Those with Other Disabilities and with Mental Health Issues: A Multicountry Study Open
Carers supporting people with an intellectual disability often rely on others to manage the burden of care. This research aims to compare the differences between carer groups and understand the predictors of loneliness changes and burden f…
View article: The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature
The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature Open
Background: In older people, dementia is a well-established risk factor for falls. However, the association and the causal relationship between falls and the earlier stages of cognitive impairment remains unclear. The purpose of the study …
View article: Personal Determinants of Information and Communication Technology (ICT) Modality by South Asian Care Partners of Individuals with Life-Limiting Health Conditions Experiencing Social Isolation and Loneliness Before and During the COVID-19 Pandemic
Personal Determinants of Information and Communication Technology (ICT) Modality by South Asian Care Partners of Individuals with Life-Limiting Health Conditions Experiencing Social Isolation and Loneliness Before and During the COVID-19 Pandemic Open
View article: Does the LHPP gene share a common biological function in pancancer progression?
Does the LHPP gene share a common biological function in pancancer progression? Open
View article: The challenges of mental health of staff working with people with intellectual disabilities during COVID-19––A systematic review
The challenges of mental health of staff working with people with intellectual disabilities during COVID-19––A systematic review Open
Background The COVID-19 pandemic has posed a great risk to the mental health of health workers (HWs). There are likely to be particular concerns for staff working with adults with an intellectual disability, where infection control may be …
View article: Effect of AMPK Subunit Alpha 2 Polymorphisms on Postherpetic Pain Susceptibility in Southwestern Han Chinese
Effect of AMPK Subunit Alpha 2 Polymorphisms on Postherpetic Pain Susceptibility in Southwestern Han Chinese Open
PHN occurrence may be related to the PRKAA2 rs10789038 A>G genetic polymorphism in the southwestern Chinese Han population.
View article: Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes
Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes Open
View article: Retracted: MiR-10b alleviates high glucose-induced human retinal endothelial cell injury by regulating TIAM1 signaling
Retracted: MiR-10b alleviates high glucose-induced human retinal endothelial cell injury by regulating TIAM1 signaling Open
This article previously published in Volume 19 Issue 8 of this journal in August 2020 has been retracted in line with the guidelines from the Committee on Publication Ethics (COPE, http://publication ethics.org/resources/guidelines).Retrac…
View article: Care partner needs of people with neurodegenerative disorders: What are the needs, and how well do the current assessment tools capture these needs? A systematic meta‐review
Care partner needs of people with neurodegenerative disorders: What are the needs, and how well do the current assessment tools capture these needs? A systematic meta‐review Open
Objectives The burden on care partners, particularly once dementia emerges, is among the greatest of all caregiving groups. This meta‐review aimed to (1) synthesis evidence on the self‐reported needs of care partners supporting people livi…
View article: Care burden, loneliness, and social isolation in caregivers of people with physical and brain health conditions in English‐speaking regions: Before and during the COVID‐19 pandemic
Care burden, loneliness, and social isolation in caregivers of people with physical and brain health conditions in English‐speaking regions: Before and during the COVID‐19 pandemic Open
Background Public health restrictions due to the COVID‐19 (SARS CoV‐2) pandemic have disproportionately affected informal caregivers of people living with long term health conditions. We aimed to explore levels of care burden, loneliness, …
View article: Dementia among international migrants: An urgent call for better care
Dementia among international migrants: An urgent call for better care Open
COMMENTARYwith large differences between regions of the country (e.g., North vs. South) [6].This latter feature may be in part explained by the reduced number of older migrants in the Southern regions of Italy, but also by the lower availa…
View article: Staff mental health while providing care to people with intellectual disability during the COVID‐19 pandemic
Staff mental health while providing care to people with intellectual disability during the COVID‐19 pandemic Open
Background The COVID‐19 pandemic has placed enormous strain on health systems around the world, undermining the mental health and wellbeing of healthcare workers. Supporting people with intellectual disabilities may be particularly challen…