Yongmei Qian
YOU?
Author Swipe
View article: Cancer-associated Fibroblasts Confer Osimertinib Resistance in Non-small Cell Lung Cancer Cells via NRG1-mediated HER3/AKT Signaling
Cancer-associated Fibroblasts Confer Osimertinib Resistance in Non-small Cell Lung Cancer Cells via NRG1-mediated HER3/AKT Signaling Open
Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI); it has achieved favorable progression-free survival (PFS) in non-small cell lung cancer (NSCLC) patients with EGFR mutation, however…
View article: Effect of Pile Spacing on Load Bearing Performance of NT-CEP Pile Group Foundation
Effect of Pile Spacing on Load Bearing Performance of NT-CEP Pile Group Foundation Open
The NT-CEP pile is an innovative type of pile that builds upon the conventional concrete straight-hole cast-in-place pile. It primarily consists of two components: the main pile and the bearing plate. The key factors influencing its load-b…
View article: Analysis of the Influence of Bearing Plate Position on the Uplift Bearing Capacity of Low-Header CEP Single-Pile Foundations
Analysis of the Influence of Bearing Plate Position on the Uplift Bearing Capacity of Low-Header CEP Single-Pile Foundations Open
This study investigates the impact of the bearing plate position on the uplift bearing capacity of low-header concrete expanded pile (CEP) foundations using the ANSYS finite element simulation method. Nine models of low-header CEP single p…
View article: Influence of bearing platform size on bearing capacity of NT-CEP pile group foundation under compound force
Influence of bearing platform size on bearing capacity of NT-CEP pile group foundation under compound force Open
The compressive bearing capacity of a new type of concrete-expanded plate pile (NT-CEP pile) is significantly affected by the size of the bearing platform; however, research in this area remains limited. Therefore, this study investigates …
View article: Theoretical study on the influence of plate end spacing on the uplift bearing capacity of CEP double-pile foundation
Theoretical study on the influence of plate end spacing on the uplift bearing capacity of CEP double-pile foundation Open
View article: Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells
Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells Open
Cancer-associated fibroblasts (CAFs) are major component of stromal cells. Growing evidence suggests that CAFs promote tumor growth and metastasis; however, the reprogramming of normal fibroblasts (NFs) into CAFs by tumor cells still remai…
View article: Finite Element Simulation Analysis of the Influence of Pile Spacing on the Uplift Bearing Performance of Concrete Expanding-Plate Pile Groups
Finite Element Simulation Analysis of the Influence of Pile Spacing on the Uplift Bearing Performance of Concrete Expanding-Plate Pile Groups Open
Concrete expanding-plate piles (CEP piles) represent a novel type of variable cross-section concrete cast-in-place pile, wherein one or more bearing plates are added to the pile body to enhance its load-bearing capacity. Compared to tradit…
View article: Effects of disc overhang diameter on the uplift bearing capacity of new-type concrete expanded-plate pile groups
Effects of disc overhang diameter on the uplift bearing capacity of new-type concrete expanded-plate pile groups Open
View article: Influence of Pile Spacing on the Compressive Bearing Performance of CEP Groups
Influence of Pile Spacing on the Compressive Bearing Performance of CEP Groups Open
Pile spacing is an important factor affecting the bearing capacity of concrete expansion pile (CEP) groups. In this study, a pile group was simulated and analyzed using ANSYS software R19.0. The influence of pile spacing on the bearing cap…
View article: High LGALS3 expression induced by HCP5/hsa-miR-27b-3p correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma
High LGALS3 expression induced by HCP5/hsa-miR-27b-3p correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma Open
View article: Effects of Staggered Plates on the Uplift Failure State and Bearing Capacity of NT-CEP Pile Groups
Effects of Staggered Plates on the Uplift Failure State and Bearing Capacity of NT-CEP Pile Groups Open
Plate position is an important parameter of a New Type Concrete Expanded-Plate (NT-CEP) pile. In this study, two small-scale test models and two, four, six, and nine finite element models were established using a visual small-scale model o…
View article: Prognostic Value and Immune Landscapes of Four Types of RNA Modification Writer-Related LncRNAs Signature in Lung Adenocarcinoma
Prognostic Value and Immune Landscapes of Four Types of RNA Modification Writer-Related LncRNAs Signature in Lung Adenocarcinoma Open
Background: Lung adenocarcinoma (LUAD) is the predominant pathological subtype of non-small cell lung cancer (NSCLC). The four primary forms of RNA adenosine modifications, N6-methyladenosine (m6A), N1-methyladenosine (m<…
View article: Influence of Plate Position on Uplift Failure State and Bearing Capacity of NT‐CEP Pile Groups
Influence of Plate Position on Uplift Failure State and Bearing Capacity of NT‐CEP Pile Groups Open
The previous research results of the research group demonstrated that the plate position is the main factor affecting the uplift bearing capacity of the new type of concrete expanded plate pile (NT‐CEP pile) group and the failure state of …
View article: Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification
Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification Open
View article: Theoretical Analysis of the Influence of Bearing Plate Position on the Bearing Performance of Soil around the CEP Antipull Force Double Pile
Theoretical Analysis of the Influence of Bearing Plate Position on the Bearing Performance of Soil around the CEP Antipull Force Double Pile Open
With the development of large-scale projects such as high-rise buildings, deep-sea platforms, bridges, etc., these construction facilities are affected by many factors such as environment and geological conditions, which put forward higher…
View article: Simulation Analysis of the Effect of Pile Spacing on the Compressive Load-Bearing Performance of CEP Double Piles
Simulation Analysis of the Effect of Pile Spacing on the Compressive Load-Bearing Performance of CEP Double Piles Open
Under the action of vertical pressure, the variation of pile spacing affects the bearing performance of concrete expanded-plate (CEP) double pile and the damaged state of soil around the pile. In this study, finite element simulation analy…
View article: Seismic-wave path attenuation and local site responses in eastern Guangdong province revealed by the ground-motion spectral analyses
Seismic-wave path attenuation and local site responses in eastern Guangdong province revealed by the ground-motion spectral analyses Open
In an effort to investigate the attenuation characteristics and site effects in eastern Guangdong, 659 strong-motion recordings received by 27 stations were selected for spectral analysis to separate path attenuation, site effects and sour…
View article: Cancer-associated fibroblasts promote migration and invasion of non-small cell lung cancer cells via METTL3-mediated RAC3 m<sup>6</sup>A modification
Cancer-associated fibroblasts promote migration and invasion of non-small cell lung cancer cells via METTL3-mediated RAC3 m<sup>6</sup>A modification Open
Cancer progression depends on the communication between tumor cells and tumor microenvironment. Cancer-associated fibroblasts (CAFs) are a major component of stromal cells. CAFs promote cancer metastasis; however, it has not been evaluated…
View article: Influence of the α Angle of Flexible Concrete Expanded-Plate Piles on the Bearing Capacity under Horizontal Load
Influence of the α Angle of Flexible Concrete Expanded-Plate Piles on the Bearing Capacity under Horizontal Load Open
Concrete expanded-plate piles have significant advantages in the bearing capacity, settlement, and construction period. The added bearing expanded plate is the key reason for their many advantages; moreover, the slope angle (α angle: the m…
View article: Study of undisturbed soil test about slope angle of the expanded-plate affecting the failure mechanism of the NT-CEP pile under vertical tension
Study of undisturbed soil test about slope angle of the expanded-plate affecting the failure mechanism of the NT-CEP pile under vertical tension Open
In this paper, it is computer simulation studied that the influence of the slope angle of expanded-plate of the new-type concrete expanded-plate pile (the NT-CEP pile) to the uplift failure mechanism. The model piles of different slope ang…
View article: Investigation on Fatigue Performance of Diatomite/Basalt Fiber Composite Modified Asphalt Mixture
Investigation on Fatigue Performance of Diatomite/Basalt Fiber Composite Modified Asphalt Mixture Open
The fatigue resistance of asphalt mixture is an important indicator to evaluate the durability of asphalt pavement. In order to improve the fatigue properties of asphalt mixture, diatomite and environmental basalt fiber were added. Four ty…
View article: INFLUENCE OF SIZE EFFECT ON THE BEARING CAPACITY OF THE AXIALLY COMPRESSED COMPONENTS OF CORN STRAW INTEGRATED MATERIAL AND ITS CALCULATION METHOD
INFLUENCE OF SIZE EFFECT ON THE BEARING CAPACITY OF THE AXIALLY COMPRESSED COMPONENTS OF CORN STRAW INTEGRATED MATERIAL AND ITS CALCULATION METHOD Open
Our paper proposed a new type of environmentally friendly biomass material, corn straw integrated material (CSIM). In this paper, the ultimate bearing capacity of the axially compressed components under parallel, vertical and combined text…
View article: An Extensive Design Approach Integrating Offshore Residential Buildings and Solar Collectors
An Extensive Design Approach Integrating Offshore Residential Buildings and Solar Collectors Open
Utilization of energy has boosted socio-economic development but meanwhile exacerbated the environmental problems. Offshore areas in China boast abundant solar energy resources. The present work explores the application of solar energy in …
View article: Study on Soil Displacement Fields around the Expanded Body of Drill-Expanded Concrete Piles Based on DIC Technique
Study on Soil Displacement Fields around the Expanded Body of Drill-Expanded Concrete Piles Based on DIC Technique Open
The soil displacement field around a drill-expanded concrete pile is noticeably different from that of an equivalent section pile placed under axial load due to the mutual embedment between the expanded body and the soil. It is important t…
View article: Theoretical study on the load carrying capacity of concrete drilled and expanded piles with different stiffness under horizontal load
Theoretical study on the load carrying capacity of concrete drilled and expanded piles with different stiffness under horizontal load Open
Concrete drilling and expanding pile is a new type of pile in the field of foundation engineering, which has been improved compared with the traditional straight-hole pile. The expansion technology improves the bearing capacity of the pile…
View article: Finite-Element Analysis on Compressive Performance of a Novel Glue-Laminated Cornstalk Scrimber
Finite-Element Analysis on Compressive Performance of a Novel Glue-Laminated Cornstalk Scrimber Open
Novel glue-laminated cornstalk scrimber is a new timber substitute produced by special techniques, without damaging the original fibers in cornstalks. This novel material outperforms ordinary timber in the resistance to water, damping, ins…
View article: Tensile Performance of a Novel Glue-Laminated Cornstalk Scrimber
Tensile Performance of a Novel Glue-Laminated Cornstalk Scrimber Open
Glue-laminated cornstalk scrimber is a novel composite to substitute timber. This composite can be prepared in three steps: selecting flawless cornstalks, laying them parallel to grain, and gluing the scrimbers under high pressure. Compare…
View article: Research on the integrated design of solar thermal energy systems and existing multi-storey residential buildings
Research on the integrated design of solar thermal energy systems and existing multi-storey residential buildings Open
To save energy and commit to the environmental protection and sustainable development of green ecological buildings, how to integrate solar energy systems with the reconstruction of multi-storey residential buildings has become a key area …
View article: Anti‐Overturning Bearing Capacity of Rigid and Flexible Concrete Expanded Piles Subjected to Horizontal Load
Anti‐Overturning Bearing Capacity of Rigid and Flexible Concrete Expanded Piles Subjected to Horizontal Load Open
The concrete expanded pile is a new type of pile in the field of foundation engineering, which exhibits improved performance compared to the ordinary straight‐hole pile. The expanded technique increases the bearing capacity of the pile, ch…
View article: Anti-PD-1 therapy combined with chemotherapy or target therapy in patients with advanced biliary tract cancer in real-world clinical setting
Anti-PD-1 therapy combined with chemotherapy or target therapy in patients with advanced biliary tract cancer in real-world clinical setting Open
Background: Biliary tract cancer (BTC) is associated with poor prognosis and lack of effective treatment. As the deregulation of the immune system playing a key role in the pathogenesis of BTC, immunotherapy has emerged as a promising trea…