Explanipedia

Neonatal outcomes among pregnant women with COVID-19: a systematic scoping review and meta-analysis Open

Yongqiu Li, Ying Lü, Huilin Tang, Eliot Spector, Xiaoxiao Wen , et al. · 2025

Correction: A scoping review of human papillomavirus related data system in China Open

Yongqiu Li, Ruixuan Wang, Jun Zhang, Yating Chen, Siyan Zhan , et al. · 2025

A scoping review of human papillomavirus related data system in China Open

Yongqiu Li, Ruixuan Wang, Jun Zhang, Yating Chen, Siyan Zhan , et al. · 2025

China has made significant progress in addressing HPV-related diseases and prevention, but more integrated and comprehensive data systems are needed to effectively support research, improve interventions, and achieve national and global go…

The complex relationships among self-acceptance, perceived social support, drug use stereotype threat, and subthreshold depression in people with substance use disorder: exploring the mediating and buffering effects Open

Yongqiu Li, Rufang Wang, Jun Liu, Zuoliang Li, Yinghua Zhou · 2025

Introduction Depression levels are significantly higher among people with substance use disorder (SUD) than in the general population; however, studies on the level of subthreshold depression in this population are scarce. Research shows a…

Factors influencing the type of self-acceptance in drug addicts and the relationship with subthreshold depression: evidence based on latent profile analysis Open

Yongqiu Li, Rufang Wang, Jun Liu, Yinghua Zhou · 2025

Heterogeneity exists in drug addicts' self-acceptance, and gender, HIV-positive or not, education level, and drug use stereotype threat are factors influencing self-acceptance in compulsory isolated drug addicts. High self-appraisal-high s…

Breast Cancer Screening and Risk of Advanced Stage Cancer Diagnosis and Mortality in Patients with Alzheimer's Disease and Related Dementias Open

Yushi Huang, Yongqiu Li, Xiwei Lou, Jessica Y. Islam, Muxuan Liang , et al. · 2025

Factors influencing the type of self-acceptance in drug addicts and the relationship with subthreshold depression: evidence based on latent profile analysis Open

Yongqiu Li, Rufang Wang, Jun Liu, Yinghua Zhou · 2024

Objective To study the heterogeneity and influencing factors of self-acceptance of drug addicts in compulsory isolation in 2 drug rehabilitation centers in Sichuan Province, and to analyze the effects of different types of self-acceptance …

Analysis of Factors Associated to Hemorrhagic Transformation After Recanalization of Acute Ischemic Stroke Open

Lei Yang, Yongqiu Li · 2024

Ischemic stroke is associated with high rates of mortality and disability, making it an urgent issue that requires immediate attention. However, patients with acute ischemic stroke (AIS) can open the occluded cerebral vessels timelier, res…

Relationship between morning blood pressure variability and cerebral microbleed burden in patients with hypertension Open

Dongsen Zhang, H. Ma, Chunqin Liu, Yongqiu Li · 2024

Cerebral microbleeds (CMBs) can be understood as a type of target organ damage caused by hypertension. We aimed to explore the association of the CMB burden with morning blood pressure (BP) variability in patients with hypertension. We div…

The Burden of Cancer and Pre-cancerous Conditions Among Transgender Individuals in a Large Healthcare Network Open

Shuang Yang, Yongqiu Li, Christopher W. Wheldon, Mattia Prosperi, Thomas J. George , et al. · 2024

The current study aimed to examine the prevalence of and risk factors for cancer and pre-cancerous conditions, comparing transgender and cisgender individuals, using 2012-2023 electronic health record data from a large healthcare system. W…

Feasibility of Identifying Factors Related to Alzheimer’s Disease and Related Dementia in Real-World Data Open

Aokun Chen, Qian Li, Yü Huang, Yongqiu Li, Yu-Neng Chuang , et al. · 2024

A comprehensive view of factors associated with AD/ADRD will significantly aid in studies to develop new treatments for AD/ADRD and identify high-risk populations and patients for prevention efforts. In our study, we summarized the risk fa…

Feasibility of Identifying Factors Related to Alzheimer's Disease and Related Dementia in Real-World Data Open

Aokun Chen, Qian Li, Yu Huang, Yongqiu Li, Yu-Neng Chuang , et al. · 2024

A comprehensive view of factors associated with AD/ADRD will significantly aid in studies to develop new treatments for AD/ADRD and identify high-risk populations and patients for prevention efforts. In our study, we summarized the risk fa…

Thrombolysis with Recombinant Human Prourokinase 4.5–6 h After Acute Ischemic Stroke: A Phase IIa, Randomized, and Open-Label Multicenter Clinical Trial Open

Haiqing Song, Yuan Wang, Qingfeng Ma, Dawei Chen, Bo Liu , et al. · 2023

Efficacy and Safety of Recombinant Human Prourokinase in the Treatment of Acute Ischemic Stroke Within 4.5 Hours of Stroke Onset Open

Haiqing Song, Yuan Wang, Qingfeng Ma, Wuwei Feng, Rui Liu , et al. · 2023

Importance Recombinant human prourokinase (rhPro-UK) is a thrombolytic agent that has shown promising findings in a phase 2 clinical trial in patients with acute ischemic stroke (AIS). Objective To evaluate the efficacy and safety of rhPro…

A Computable Phenotype for the Identification of Sexual and Gender Minorities in Electronic Health Records. Open

Yongqiu Li, Xing He, Christopher W. Wheldon, Yonghui Wu, Mattia Prosperi , et al. · 2023

Sexual gender minorities, including lesbian, gay, and bisexual (LGB) individuals face unique challenges due to discrimination, stigma, and marginalization, which negatively impact their well-being. Electronic health record (EHR) systems pr…

The Impact of Race–Ethnicity and Diagnosis of Alzheimer’s Disease and Related Dementias on Mammography Use Open

Aokun Chen, Yongqiu Li, Jennifer Woodard, Jessica Y. Islam, Shuang Yang , et al. · 2022

Breast cancer screening (BCS) with mammography is a crucial method for improving cancer survival. In this study, we examined the association of Alzheimer’s disease (AD) and AD-related dementias (ADRD) diagnosis and race–ethnicity with mamm…

Risk factors and predictive scoring system for twice or more strokes in patients with cerebral small vessel disease Open

Jiali Ma, Yongqiu Li, Hongying Ma, Haifeng Gao, Xuan Gao , et al. · 2022

Objectives To explore the independent risk factors of twice or more strokes in patients with cerebral small vessel disease, and to construct a predictive scoring system. Methods A retrospective study was carried out in Tangshan, Hebei Prov…

Clinical Prediction Model for Screening Acute Ischemic Stroke Patients With More Than 10 Cerebral Microbleeds Open

Yifan Li, Haifeng Gao, Dongsen Zhang, Xuan Gao, Lin Lu , et al. · 2022

Background Hemorrhagic transformation is one of the most serious complications in intravenous thrombolysis. Studies show that the existence of more than 10 cerebral microbleeds is strongly associated with hemorrhagic transformation. The cu…

Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke Open

Yongjun Wang, Yuesong Pan, Hao Li, Pierre Amarenco, Hans Denison , et al. · 2021

ClinicalTrials.gov Identifier: NCT03354429.

Unilateral cerebral cortical encephalitis (CCE) with positive anti-MOG antibodies Open

Hongbing Nie, Haifeng Gao, Yongqiu Li, Yaoyao Shen · 2021

Rationale: Nowadays, myelin oligodendrocyte glycoprotein (MOG)-antibody-associated disease (MOGAD) is regarded as an independent inflammatory demyelinating disease. Here, we report a rare case of unilateral cerebral cortical encephalitis (…

2020 expert consensus statement on neuro-protection after cardiac arrest in China Open

Qingbian Ma, Liqun Feng, Tao Wang, Yongqiu Li, LI Zhen-zhong , et al. · 2021

Data and Model Biases in Social Media Analyses: A Case Study of COVID-19 Tweets. Open

Yunpeng Zhao, Pengfei Yin, Yongqiu Li, Xing He, Jingcheng Du , et al. · 2021

During the coronavirus disease pandemic (COVID-19), social media platforms such as Twitter have become a venue for individuals, health professionals, and government agencies to share COVID-19 information. Twitter has been a popular source …

Ticagrelor Added to Aspirin in Acute Nonsevere Ischemic Stroke or Transient Ischemic Attack of Atherosclerotic Origin Open

Pierre Amarenco, Hans Denison, Scott Evans, Anders Himmelmänn, Stefan James , et al. · 2020

Background and Purpose: Among patients with a transient ischemic attack or minor ischemic strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the highest risk of recurrent vascular events. Methods: I…

Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Transient Ischemic Attack in Prevention of Disabling Stroke Open

Pierre Amarenco, Hans Denison, Scott Evans, Anders Himmelmänn, Stefan James , et al. · 2020

ClinicalTrials.gov Identifier: NCT03354429.

Downregulation of microRNA‑451 improves cell migration, invasion and tube formation in hypoxia‑treated HUVECs by targeting MIF Open

Qian Li, Yongqiu Li, Dongsen Zhang, Haifeng Gao, Xuan Gao · 2019

Angiogenesis is a critical process of recovery from cerebrovascular disease. A growing body of evidence has confirmed that microRNAs (miRNAs/miRs) have an important role in the modulation of angiogenesis under physiological and pathologica…

Exploring Lung Cancer Screening Discussions on Twitter Open

Yunpeng Zhao, Jinhai Huo, Mattia Prosperi, Yi Guo, Yongqiu Li , et al. · 2019

Lung cancer is the leading cause of cancer-related death in the United States. Low-dose computed tomography (LDCT) for lung cancer screening (LCS) can reduce lung cancer deaths by 20% compared to chest x-rays. Nevertheless, the uptake of L…

Early antihypertensive treatment and clinical outcomes in acute ischemic stroke Open

William He, Chongke Zhong, Tan Xu, Dali Wang, Yingxian Sun , et al. · 2018

ClinicalTrials.gov Identifier: NCT01840072.

Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke Open

Chongke Zhong, Jingyuan Yang, Tan Xu, Tian Xu, Yanbo Peng , et al. · 2017

Higher serum MMP-9 levels in the acute phase of ischemic stroke were associated with increased risk of mortality and major disability, suggesting that serum MMP-9 could be an important prognostic factor for ischemic stroke.

Blood pressure reduction in acute ischemic stroke according to time to treatment Open

Tan Xu, Yonghong Zhang, Xiaoqing Bu, Dali Wang, Yingxian Sun , et al. · 2017

ClinicalTrials.gov Identifier: NCT01840072.

Sex-specific Association Between Uric Acid and Outcomes After Acute Ischemic Stroke: A Prospective Study from CATIS Trial Open

Lihua Chen, Chongke Zhong, Tan Xu, Tian Xu, Yanbo Peng , et al. · 2016

The relationship between serum uric acid (UA) and outcomes after acute ischemic stroke remains debatable in human studies, and the sex effect on this association has yet to be explored. Here, we investigated these associations in a prospec…

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