Yongquan Lin
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View article: Double Orientation Integrated Cutting Tool Wear for Surface Milling Multi-Directional Cfrp with Ball-End Cutter
Double Orientation Integrated Cutting Tool Wear for Surface Milling Multi-Directional Cfrp with Ball-End Cutter Open
View article: Double orientation integrated cutting tool wear for surface milling multi-directional CFRP with ball-end cutter
Double orientation integrated cutting tool wear for surface milling multi-directional CFRP with ball-end cutter Open
View article: A multicenter prospective study of comprehensive metagenomic and transcriptomic signatures for predicting outcomes of patients with severe community-acquired pneumonia
A multicenter prospective study of comprehensive metagenomic and transcriptomic signatures for predicting outcomes of patients with severe community-acquired pneumonia Open
National Natural Science Foundation of China (No. 82161138018), Shanghai Municipal Key Clinical Specialty (shslczdzk02202), Shanghai Top-Priority Clinical Key Disciplines Construction Project (2017ZZ02014), Shanghai Key Laboratory of Emerg…
View article: Introducing big data to measure the spatial heterogeneity of human activities for optimizing the ecological security pattern: A case study from Guangzhou City, China
Introducing big data to measure the spatial heterogeneity of human activities for optimizing the ecological security pattern: A case study from Guangzhou City, China Open
Spatial heterogeneity of human activities (SHHA) is part of the heterogeneity of urban ecosystems, which influences the understanding of ecological processes and landscape functions. Few ecological security pattern (ESP) studies have compr…
View article: Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Open
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public health. However, efforts to identify effectively supportive therapeutic drugs and tre…
View article: Inconsistent Patterns of Soil Fauna Biodiversity and Soil Physicochemical Characteristic Along an Urbanization Gradient
Inconsistent Patterns of Soil Fauna Biodiversity and Soil Physicochemical Characteristic Along an Urbanization Gradient Open
Urbanization has induced substantial changes in soil physicochemical characteristic, which plays an important role in regulating soil fauna biodiversity in forests and grasslands. However, less is known about the urbanization effect on soi…
View article: Enterovirus 71 Activates GADD34 via Precursor 3CD to Promote IRES-Mediated Viral Translation
Enterovirus 71 Activates GADD34 via Precursor 3CD to Promote IRES-Mediated Viral Translation Open
Identification of host factors involved in viral replication is an important approach in discovering viral pathogenic mechanisms and identifying potential therapeutic targets. Previously, we screened host proteins that were upregulated by …
View article: Environmental evolution of Lake Taibai (Hubei Province) over the past century revealed by cladoceran subfossils
Environmental evolution of Lake Taibai (Hubei Province) over the past century revealed by cladoceran subfossils Open
During the past century, shallow lakes in the middle and lower reaches of the Yangtze River experienced climate change and increasing human disturbance, resulting in widespread lake eutrophication, regime shifts of hydrodynamic condition a…
View article: Identification of the internal ribosome entry sites in the 5'‑untranslated region of the <i>c‑fos</i> gene
Identification of the internal ribosome entry sites in the 5'‑untranslated region of the <i>c‑fos</i> gene Open
The Fos proto‑oncogene, activator protein‑1 (AP‑1) transcription factor subunit (c‑fos) gene, a member of the immediate early gene family, encodes c‑Fos, which is a subunit of the AP‑1 transcription factor. The present study aimed t…
View article: Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Open
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public health. However, efforts to identify effectively supportive therapeutic drugs and tre…
View article: Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Open
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public health. However, efforts to identify effectively supportive therapeutic drugs and tre…
View article: Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Open
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public health. However, efforts to identify effectively supportive therapeutic drugs and tre…
View article: MicroRNA‑539 inhibits cell proliferation, colony formation and invasion in pancreatic ductal adenocarcinoma by directly targeting IGF‑1R
MicroRNA‑539 inhibits cell proliferation, colony formation and invasion in pancreatic ductal adenocarcinoma by directly targeting IGF‑1R Open
MicroRNAs (miRNAs) possess oncogenic and tumour‑suppressive roles in the carcinogenesis and progression of pancreatic ductal adenocarcinoma (PDAC) by regulating the expression of numerous cancer‑related genes. Thus, the investigation on th…
View article: Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff Open
View article: Excessive nNOS/NO/AMPK signaling activation mediated by the blockage of the CBS/H2S system contributes to oxygen-glucose deprivation-induced endoplasmic reticulum stress in PC12 cells
Excessive nNOS/NO/AMPK signaling activation mediated by the blockage of the CBS/H2S system contributes to oxygen-glucose deprivation-induced endoplasmic reticulum stress in PC12 cells Open
Hypoxic‑ischemia stress causes severe brain injury, leading to death and disability worldwide. Although it has been reported that endoplasmic reticulum (ER) stress is an essential step in the progression of hypoxia or ischemia‑induced brai…
View article: Enterovirus 71 3C Promotes Apoptosis through Cleavage of PinX1, a Telomere Binding Protein
Enterovirus 71 3C Promotes Apoptosis through Cleavage of PinX1, a Telomere Binding Protein Open
Enterovirus 71 (EV71) is an emerging pathogen causing hand, foot, and mouth disease (HFMD) and fatal neurological diseases in infants and young children due to their underdeveloped immunocompetence. EV71 infection can induce cellular apopt…
View article: HIV-1 Vpr protein activates the NF-κB pathway to promote G2/M cell cycle arrest
HIV-1 Vpr protein activates the NF-κB pathway to promote G2/M cell cycle arrest Open