Yongquan Zheng
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View article: Extracellular matrix dysregulation in PCOS: pathogenesis, therapeutic strategies, and innovative technologies
Extracellular matrix dysregulation in PCOS: pathogenesis, therapeutic strategies, and innovative technologies Open
View article: Elucidating the Molecular Mechanisms of Hederagenin-Regulated Mitophagy in Cervical Cancer SiHa Cells through an Integrative Approach Combining Proteomics and Advanced Network Association Algorithm
Elucidating the Molecular Mechanisms of Hederagenin-Regulated Mitophagy in Cervical Cancer SiHa Cells through an Integrative Approach Combining Proteomics and Advanced Network Association Algorithm Open
Hederagenin (Hed), a natural triterpenoid, exhibits antitumor potential in cervical cancer. The present study was designed to explore Hed's regulatory mechanisms on mitophagy in SiHa cervical cancer cells, employing tandem mass tag (TMT) p…
View article: Unraveling shared diagnostic genes and cellular microenvironmental changes in endometriosis and recurrent implantation failure through multi-omics analysis
Unraveling shared diagnostic genes and cellular microenvironmental changes in endometriosis and recurrent implantation failure through multi-omics analysis Open
Endometriosis and Recurrent Implantation Failure (RIF) are both pivotal clinical issues within the realm of reproductive medicine, sharing significant overlap in their pathophysiological mechanisms. However, research exploring the commonal…
View article: Abiotic Degradation of Isofetamid in Aquatic Environments: Kinetics, Mechanisms, and Toxicity Evaluation
Abiotic Degradation of Isofetamid in Aquatic Environments: Kinetics, Mechanisms, and Toxicity Evaluation Open
View article: Abiotic Degradation of Isofetamid in Aquatic Environments: Kinetics, Mechanisms, and Toxicity Evaluation
Abiotic Degradation of Isofetamid in Aquatic Environments: Kinetics, Mechanisms, and Toxicity Evaluation Open
View article: Degradation of a novel herbicide fluchloraminopyr in soil: Dissipation kinetics, degradation pathways, transformation products identification and ecotoxicity assessment
Degradation of a novel herbicide fluchloraminopyr in soil: Dissipation kinetics, degradation pathways, transformation products identification and ecotoxicity assessment Open
With the continuous application of new agricultural chemicals in agricultural systems, it is imperative to study the environmental fate and potential transformation products (TPs) of these chemicals to better assess their ecological and he…
View article: Thiophanate-methyl and its major metabolite carbendazim weaken rhizobacteria-mediated defense responses in cucumbers against Fusarium wilt
Thiophanate-methyl and its major metabolite carbendazim weaken rhizobacteria-mediated defense responses in cucumbers against Fusarium wilt Open
The effect of fungicides on the plant-rhizosphere microbiome is a subject of ongoing debate, but whether any alteration in the rhizosphere microbiome could affect plant health is an issue that has not been thoroughly investigated. To addre…
View article: Enantioselective differentiation of chiral succinate dehydrogenase inhibitor fungicides
Enantioselective differentiation of chiral succinate dehydrogenase inhibitor fungicides Open
Chiral succinate dehydrogenase inhibitor (SDHI) fungicides have undergone rapid development and extensive application in plant protection. Due to the common existing differences in bioactivity, toxicity, and environmental behavior between …
View article: Biochar prevents soybean seedling injury caused by atrazine residue by regulating the concentration of this herbicide in soil pore water
Biochar prevents soybean seedling injury caused by atrazine residue by regulating the concentration of this herbicide in soil pore water Open
The residue of atrazine in field soils poses a major threat to crop growth in the rotation system, raising concerns about grain security and food safety. Current agricultural production requires more efficient and cost-effective mitigation…
View article: Quantitative screening of organophosphorus and organochlorine pesticides in water and soil using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry
Quantitative screening of organophosphorus and organochlorine pesticides in water and soil using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry Open
Organophosphorus and organochlorine pesticides, historically or currently widely used in agriculture, are prevalent in the environment and pose significant risks to public health and ecosystems. This study aimed to develop a robust analyti…
View article: Optimizing Analysis Methods: Rapid and Accurate Determination of Cuaminosulfate Residues with LC-MS/MS Based on Box–Behnken Design Study
Optimizing Analysis Methods: Rapid and Accurate Determination of Cuaminosulfate Residues with LC-MS/MS Based on Box–Behnken Design Study Open
In view of the defects in the previous detection of cuaminosulfate, which only focused on the analysis of copper ions, there is currently no analysis method available to determine the actual state of cuaminosulfate as chelated or bound. In…
View article: Gut microbiota-derived metabolites associate with circulating immune cell subsets in unexplained recurrent spontaneous abortion
Gut microbiota-derived metabolites associate with circulating immune cell subsets in unexplained recurrent spontaneous abortion Open
Currently, the precise causes of over 40 % of recurrent spontaneous abortion (RSA) cases cannot be identified, leading to the term "unexplained RSA" (URSA). Through an exploration of the gut microbiota, metabolites, and immune cell subsets…
View article: Effects of Fungicides and Nontarget Pesticides on Accumulation of the Mycotoxin Deoxynivlenol in Wheat
Effects of Fungicides and Nontarget Pesticides on Accumulation of the Mycotoxin Deoxynivlenol in Wheat Open
Deoxynivalenol (DON) is an important virulence factor of the Fusarium head blight of wheat and threatens the health of humans. The effect of fungicides on DON production after stressing wheat to produce H2O2 and the effect of nontarget pes…
View article: Highly-Selective Analytical Strategy for 90 Pesticides and Metabolites Residues in Fish and Shrimp Samples
Highly-Selective Analytical Strategy for 90 Pesticides and Metabolites Residues in Fish and Shrimp Samples Open
The analysis of pesticide residues in aquatic products is challenging due to low residue levels and the complex matrix interference. In this study, we developed a simple, fast method for the trace analysis of 90 pesticides and metabolites …
View article: Spontaneous In-Source Fragmentation Reaction Mechanism and Highly Sensitive Analysis of Dicofol by Electrospray Ionization Mass Spectrometry
Spontaneous In-Source Fragmentation Reaction Mechanism and Highly Sensitive Analysis of Dicofol by Electrospray Ionization Mass Spectrometry Open
Although dicofol has been widely banned all over the world as a kind of organochlorine contaminant, it still exists in the environment. This study developed a high-performance liquid chromatography coupled with mass spectrometry (HPLC-MS/M…
View article: Catalytic degradation of dimethomorph by nitrogen-doped rice husk biochar
Catalytic degradation of dimethomorph by nitrogen-doped rice husk biochar Open
N-doped biochar is widely used for activating persulfate to degrade organic pollutants. Which type of N atom is the key factor for activation is still unclear and needs to be further explored and analyzed. In this study, four kinds of bioc…
View article: Zif-8 and Humic Acid Modified Magnetic Corn Stalk Biochar: An Efficient, Magnetically Stable, and Eco-Friendly Adsorbent for Imidacloprid and Thiamethoxam Removal
Zif-8 and Humic Acid Modified Magnetic Corn Stalk Biochar: An Efficient, Magnetically Stable, and Eco-Friendly Adsorbent for Imidacloprid and Thiamethoxam Removal Open
View article: Assessment on the Stereoselective Behavior of Cyflumetofen to Earthworm (Eisenia Foetida): Degradation, Bioaccumulation, Toxicity Mechanism, and Metabolites
Assessment on the Stereoselective Behavior of Cyflumetofen to Earthworm (Eisenia Foetida): Degradation, Bioaccumulation, Toxicity Mechanism, and Metabolites Open
View article: A Sensitive Fluoroimmunoassay for Quantitative Detection of Imidacloprid Based on Quantum Dot-Streptavidin Conjugate
A Sensitive Fluoroimmunoassay for Quantitative Detection of Imidacloprid Based on Quantum Dot-Streptavidin Conjugate Open
View article: Highly Sensitive Analysis of Dicofol in Ultrahigh-Performance Liquid Chromatography-Electrospray Ionization-Mass Spectrometry by In-Source Fragmentation Reaction and the Study on the Spontaneous Reaction Mechanism
Highly Sensitive Analysis of Dicofol in Ultrahigh-Performance Liquid Chromatography-Electrospray Ionization-Mass Spectrometry by In-Source Fragmentation Reaction and the Study on the Spontaneous Reaction Mechanism Open
View article: Dissipation dynamics and comparative dietary exposure assessment of mefentrifluconazole in rice
Dissipation dynamics and comparative dietary exposure assessment of mefentrifluconazole in rice Open
A fast and sensitive analytical method based on UHPLC coupled with tandem mass spectrometry was established to investigate the dissipation and final residual amounts of mefentrifluconazole in rice, and dietary risk to consumers was evaluat…
View article: Modified Biochar as a More Promising Amendment Agent for Remediation of Pesticide-Contaminated Soils: Modification Methods, Mechanisms, Applications, and Future Perspectives
Modified Biochar as a More Promising Amendment Agent for Remediation of Pesticide-Contaminated Soils: Modification Methods, Mechanisms, Applications, and Future Perspectives Open
With the acceleration of the process of agricultural modernization, many pesticides (insecticides, fungicides, and herbicides) are applied to the field and finally brought into the soils, causing serious damage to the environment. The prob…
View article: WITHDRAWN: Development of a quantitative screening method for 100 pesticides in plant- derived foods using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry
WITHDRAWN: Development of a quantitative screening method for 100 pesticides in plant- derived foods using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry Open
View article: Insight into the uptake and metabolism of a new insecticide cyetpyrafen in plants
Insight into the uptake and metabolism of a new insecticide cyetpyrafen in plants Open
As new agrochemicals are continuously introduced into agricultural systems, it is essential to investigate their uptake and metabolism by plants to better evaluate their fate and accumulation in crops and the subsequent risks to human expo…
View article: Differential effects of ketoconazole, fluconazole, and itraconazole on the pharmacokinetics of pyrotinib in vitro and in vivo
Differential effects of ketoconazole, fluconazole, and itraconazole on the pharmacokinetics of pyrotinib in vitro and in vivo Open
It has been reported that drug-drug interactions (DDIs) can affect the pharmacokinetics and pharmacodynamics of various oral drugs. To better understand the effects of azole antifungal drugs (ketoconazole, fluconazole, and itraconazole) on…
View article: Efficiency of Four Extraction Methods to Assess the Bioavailability of Oxyfluorfen to Earthworms in Soil Amended with Fresh and Aged Biochar
Efficiency of Four Extraction Methods to Assess the Bioavailability of Oxyfluorfen to Earthworms in Soil Amended with Fresh and Aged Biochar Open
Due to its high persistence in soil, oxyfluorfen has negative effects on environmental and human health. To reduce soil contamination and impacts on non-target organisms, biochar is introduced into soils to immobilize and sequestrate oxyfl…
View article: Regulatory Role and Potential Importance of GDF-8 in Ovarian Reproductive Activity
Regulatory Role and Potential Importance of GDF-8 in Ovarian Reproductive Activity Open
Growth differentiation factor-8 (GDF-8) is a member of the transforming growth factor-beta superfamily. Studies in vitro and in vivo have shown GDF-8 to be involved in the physiology and pathology of ovarian reproductive functions. In vitr…
View article: Characterization of Montmorillonite–Biochar Composite and Its Application in the Removal of Atrazine in Aqueous Solution and Soil
Characterization of Montmorillonite–Biochar Composite and Its Application in the Removal of Atrazine in Aqueous Solution and Soil Open
Atrazine is a widely used triazine herbicide, which poses a serious threat to human health and aquatic ecosystem. A montmorillonite–biochar composite (MMT/BC) was prepared for atrazine remediation. Biochar samples were characterized by usi…
View article: Short‐chain fatty acids regulate B cells differentiation via the FFA2 receptor to alleviate rheumatoid arthritis
Short‐chain fatty acids regulate B cells differentiation via the FFA2 receptor to alleviate rheumatoid arthritis Open
Background and Purpose Short‐chain fatty acids (SCFAs) are metabolites from gut microbes involved in the host's inflammatory response and immunity. The aim of this study was to investigate the role of SCFAs in rheumatoid arthritis (RA) and…
View article: Trifluralin Impacts Soil Microbial Community and Functions
Trifluralin Impacts Soil Microbial Community and Functions Open
A 3-month experiment was designed to research the impact of trifluralin (TFL) on soil microbial communities and functions under the condition of greenhouse. In this work, silty loam from Langfang was treated with three doses of TFL (1,260,…