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View article: Microenvironment-responsive multifunctional enzyme-linked hydrogel for diabetic bone defect regeneration
Microenvironment-responsive multifunctional enzyme-linked hydrogel for diabetic bone defect regeneration Open
Diabetes mellitus (DM) bone defects face impaired healing due to hyperglycemia, chronic inflammation, and dysregulated bone remodeling, yet existing therapies lack comprehensive strategies targeting these interconnected issues. Herein, a g…
View article: Oxygen‐Releasing Hydrogels in Biomedicine: Present and Future
Oxygen‐Releasing Hydrogels in Biomedicine: Present and Future Open
Oxygen‐releasing hydrogels (ORHs) have emerged as innovative biomedical platforms capable of delivering controlled oxygen through chemical, physical, or biological mechanisms, demonstrating significant potential in enhancing tissue regener…
View article: A sandwich-like nanofibrous scaffold with macrophage phenotype transformation and myogenic differentiation for skeletal muscle regeneration
A sandwich-like nanofibrous scaffold with macrophage phenotype transformation and myogenic differentiation for skeletal muscle regeneration Open
View article: Back Cover: Revolutionizing Bone Regeneration: Vascularized Bone Tissue Engineering with Advanced 3D Printing Technology
Back Cover: Revolutionizing Bone Regeneration: Vascularized Bone Tissue Engineering with Advanced 3D Printing Technology Open
View article: Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface
Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface Open
View article: Revolutionizing Bone Regeneration: Vascularized Bone Tissue Engineering with Advanced 3D Printing Technology
Revolutionizing Bone Regeneration: Vascularized Bone Tissue Engineering with Advanced 3D Printing Technology Open
The repair and functional reconstruction of bone defects resulting from trauma, surgical resection, degenerative diseases, and congenital malformations are major clinical challenges. Bone tissue engineering has significant advantages in th…
View article: A Sandwich-Like Nanofibrous Scaffold with Macrophage Reprogramming and Myogenic Differentiation for Muscle Regeneration
A Sandwich-Like Nanofibrous Scaffold with Macrophage Reprogramming and Myogenic Differentiation for Muscle Regeneration Open
View article: Multifunctional and immunoregulatory microenvironment-responsive hydrogel for whole course management of infected diabetic wounds
Multifunctional and immunoregulatory microenvironment-responsive hydrogel for whole course management of infected diabetic wounds Open
View article: Association between disease activity of rheumatoid arthritis and risk of complications following total hip arthroplasty: a retrospective cohort study
Association between disease activity of rheumatoid arthritis and risk of complications following total hip arthroplasty: a retrospective cohort study Open
Background Identifying rheumatoid arthritis patients at higher risk of complications after total hip arthroplasty could make perioperative management more effective. Here we examined whether disease activity is associated with risk of such…
View article: Perioperative Short‐Term Glucocorticoids Do Not Increase Incidence of Complications after Total Joint Arthroplasty in Patients with Rheumatoid Arthritis
Perioperative Short‐Term Glucocorticoids Do Not Increase Incidence of Complications after Total Joint Arthroplasty in Patients with Rheumatoid Arthritis Open
Objectives The safety and analgesic efficacy of perioperative glucocorticoids have been established for patients without rheumatoid arthritis. Therefore, our study aims to investigate whether similar benefits can be observed in patients wi…
View article: The Long‐term Efficacy of Total Knee Arthroplasty on End‐stage <scp>Kashin–Beck</scp> Disease of the Knee in Highland Tibetan Areas Patients: A Retrospective Study with 10‐Year Follow‐up
The Long‐term Efficacy of Total Knee Arthroplasty on End‐stage <span>Kashin–Beck</span> Disease of the Knee in Highland Tibetan Areas Patients: A Retrospective Study with 10‐Year Follow‐up Open
Objective Despite the established success of total knee arthroplasty (TKA) with end‐stage osteoarthritis, there is a notable scarcity of research on its long‐term outcomes in individuals suffering from end‐stage Kashin–Beck disease (KBD). …
View article: Multifunctional mesoporous polydopamine near-infrared photothermal controlled release of kartogenin for cartilage repair
Multifunctional mesoporous polydopamine near-infrared photothermal controlled release of kartogenin for cartilage repair Open
Improving chondrogenic differentiation while inhibiting hypertrophic differentiation of mesenchymal stem cells (MSCs) is of vital importance to effectively repairing cartilage injury. Accordingly, kartogenin (KGN) and antioxidants, which p…
View article: Inflammation induced epigenetic activation of bivalent genes in osteoarthritic cartilage
Inflammation induced epigenetic activation of bivalent genes in osteoarthritic cartilage Open
Osteoarthritis (OA) is the most prevalent joint disorder occurring with articular cartilage degradation, which includes a switch from an articular to a growth-plate chondrocyte phenotype. Epigenetics serves as a new therapeutic target but …
View article: Pharmacological use of gamma-aminobutyric acid derivatives in osteoarthritis pain management: a systematic review
Pharmacological use of gamma-aminobutyric acid derivatives in osteoarthritis pain management: a systematic review Open
View article: Pharmacological Use of Gamma-Aminobutyric Acid Derivatives in Osteoarthritis Pain Management: A Systematic Review
Pharmacological Use of Gamma-Aminobutyric Acid Derivatives in Osteoarthritis Pain Management: A Systematic Review Open
Background Pain is the major complication of osteoarthritis (OA) patients and is a decisive symptom for medical intervention. Gamma-aminobutyric acid (GABA) derivatives are optional painkillers but not widely used in pain management of OA …
View article: Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study
Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study Open
View article: Does systemic lupus erythematosus increase the risk of complications from total hip arthroplasty?
Does systemic lupus erythematosus increase the risk of complications from total hip arthroplasty? Open